Published in Biophys Chem on February 01, 1981
Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation. Proc Natl Acad Sci U S A (2004) 2.74
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet (1999) 7.04
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. Nature (1994) 4.28
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med (2001) 4.17
A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat Med (1995) 2.65
Advances in the gas chromatographic analysis of amino acid phenyl- and methylthiohydantoins. Anal Biochem (1972) 2.56
Human apolipoprotein B-100: cloning, analysis of liver mRNA, and assignment of the gene to chromosome 2. Proc Natl Acad Sci U S A (1985) 2.53
Cellular localization and trafficking of the human ABCA1 transporter. J Biol Chem (2001) 2.26
Bovine parathyroid hormone: amino acid sequence. Proc Natl Acad Sci U S A (1970) 2.08
Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively. Am J Hum Genet (2001) 2.08
Cardiovascular features of homozygous familial hypercholesterolemia: analysis of 16 patients. Am J Cardiol (1984) 1.99
Abnormal in vivo metabolism of apolipoprotein E4 in humans. J Clin Invest (1986) 1.98
Apolipoprotein specificity for lipid efflux by the human ABCAI transporter. Biochem Biophys Res Commun (2001) 1.91
Familial apolipoprotein E deficiency. J Clin Invest (1986) 1.87
The amino acid sequence of human APOA-I, an apolipoprotein isolated from high density lipoproteins. Biochem Biophys Res Commun (1978) 1.75
A mutation in apolipoprotein A-I in the Iowa type of familial amyloidotic polyneuropathy. Genomics (1990) 1.74
Quantitation of plasma apolipoproteins in the primary and secondary prevention of coronary artery disease. Ann Intern Med (1994) 1.70
Amino acid sequence of human apoLp-Gln-II (apoA-II), an apolipoprotein isolated from the high-density lipoprotein complex. Proc Natl Acad Sci U S A (1972) 1.68
The plasma lipoproteins. Adv Protein Chem (1977) 1.65
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice. J Clin Invest (2001) 1.61
Plasma apolipoprotein A-1 absence associated with a marked reduction of high density lipoproteins and premature coronary artery disease. Arteriosclerosis (1982) 1.57
Undifferentiated febrile illnesses amongst British troops in Helmand, Afghanistan. J R Army Med Corps (2011) 1.51
Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding. Biochemistry (1975) 1.50
Elevated plasma lipoprotein(a) in patients with the nephrotic syndrome. Ann Intern Med (1993) 1.50
Interaction of choleragen with the oligosaccharide of ganglioside GM1: evidence for multiple oligosaccharide binding sites. Biochemistry (1978) 1.50
High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase. Nat Med (1997) 1.48
Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I). Biochem Biophys Res Commun (1980) 1.46
Abnormal metabolism of shellfish sterols in a patient with sitosterolemia and xanthomatosis. J Clin Invest (1986) 1.46
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred. Proc Natl Acad Sci U S A (1999) 1.42
Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence. Proc Natl Acad Sci U S A (1986) 1.42
Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease). Ann Intern Med (1980) 1.41
NIH conference. Type III hyperlipoproteinemia: diagnosis, molecular defects, pathology, and treatment. Ann Intern Med (1983) 1.36
Isolation and characterization of apoLp-Gln-II (apoA-II), a plasma high density apolipoprotein containing two identical polypeptide chains. J Biol Chem (1972) 1.36
3-Hydroxy-3-methylglutaryl coenzyme A reductase: regulation of enzymatic activity by phosphorylation and dephosphorylation. Proc Natl Acad Sci U S A (1978) 1.34
Isolation and characterization of apolipoproteins A-I, A-II, and A-IV. Methods Enzymol (1986) 1.34
Pectin methylesterase inhibitor. Biochim Biophys Acta (2004) 1.34
Human chylomicron apolipoprotein metabolism. Biochem Biophys Res Commun (1978) 1.34
Decreased reverse cholesterol transport from Tangier disease fibroblasts. Acceptor specificity and effect of brefeldin on lipid efflux. Arterioscler Thromb Vasc Biol (1997) 1.32
Human apolipoprotein A-I and A-II metabolism. J Lipid Res (1982) 1.32
The amino acid sequence of porcine thyrocalcitonin. Proc Natl Acad Sci U S A (1968) 1.31
Studies on inactivation of lipoprotein lipase: role of the dimer to monomer dissociation. Biochemistry (1985) 1.30
Type III hyperlipoproteinemia: defective metabolism of an abnormal apolipoprotein E. Science (1981) 1.29
Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis. Proc Natl Acad Sci U S A (1996) 1.27
Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. Proc Natl Acad Sci U S A (2000) 1.26
A glycoprotein inhibitor of pectin methylesterase in kiwi fruit (Actinidia chinensis). Eur J Biochem (1990) 1.26
The association of LDL receptor activity, LDL cholesterol level, and clinical course in homozygous familial hypercholesterolemia. Metabolism (1985) 1.23
Metabolism of high-density lipoprotein apolipoproteins in Tangier disease. N Engl J Med (1978) 1.23
Human parathyroid hormone: amino-acid sequence of the amino-terminal residues 1-34. Proc Natl Acad Sci U S A (1972) 1.22
The effects of estrogen administration on plasma lipoprotein metabolism in premenopausal females. J Clin Endocrinol Metab (1983) 1.22
The complete amino acid sequence of alanine apolipoprotein (apoC-3), and apolipoprotein from human plasma very low density lipoproteins. J Biol Chem (1974) 1.22
Adrenal cholesterol uptake from plasma lipoproteins: regulation by corticotropin. Proc Natl Acad Sci U S A (1976) 1.21
Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice. J Biol Chem (1999) 1.21
Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice. J Biol Chem (2001) 1.21
Determination of tyrosine exposure in proteins by second-derivative spectroscopy. Biochemistry (1984) 1.21
Increased prevalence of apolipoprotein E4 in type V hyperlipoproteinemia. J Clin Invest (1982) 1.20
Regulation of liver 3-hydroxy-3-methylglutaryl-CoA reductase. Curr Top Cell Regul (1981) 1.20
Purification and properties of calmodulin-stimulated phosphodiesterase from mammalian brain. J Biol Chem (1984) 1.19
Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects. J Clin Invest (1984) 1.18
Cubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosis. Proc Natl Acad Sci U S A (1999) 1.18
Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production. J Clin Invest (1993) 1.17
3-Hydroxy-3-methylglutaryl--coenzyme A reductase inhibitors in the treatment of hypercholesterolemia. JAMA (1987) 1.17
Lipid-protein interactions in high density lipoproteins. Proc Natl Acad Sci U S A (1974) 1.17
Two-dimensional electrophoresis of human plasma apolipoproteins. Clin Chem (1984) 1.17
Escherichia coli heat-labile enterotoxin. Ganglioside specificity and ADP-ribosyltransferase activity. J Biol Chem (1981) 1.16
Sulfobetaine derivatives of bile acids: nondenaturing surfactants for membrane biochemistry. Anal Biochem (1983) 1.15
Cholesteryl ester storage disease and Wolman disease: phenotypic variants of lysosomal acid cholesteryl ester hydrolase deficiency. Am J Hum Genet (1984) 1.15
New micromethod for measuring cholesterol in plasma lipoprotein fractions. Clin Chem (1977) 1.15
The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate. J Clin Invest (1994) 1.14
Pet rats as a source of hantavirus in England and Wales, 2013. Euro Surveill (2013) 1.14
Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL. J Biol Chem (1997) 1.13
Identification of a novel in-frame translational stop codon in human intestine apoB mRNA. Biochem Biophys Res Commun (1987) 1.13
Plasma-triglycerides in regulation of H.D.L.-cholesterol levels. Lancet (1978) 1.13
Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia. J Clin Invest (1986) 1.13
Apolipoprotein EBethesda: a new variant of apolipoprotein E associated with type III hyperlipoproteinemia. J Clin Endocrinol Metab (1983) 1.13
The molecular biology of human apoA-I, apoA-II, apoC-II and apoB. Adv Exp Med Biol (1986) 1.12
Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen. Proc Natl Acad Sci U S A (1977) 1.11
Lipoprotein abnormalities in primary biliary cirrhosis. Association with hepatic lipase inhibition as well as altered cholesterol esterification. Gastroenterology (1985) 1.11
Erdheim-Chester disease: a rare multisystem histiocytic disorder associated with interstitial lung disease. Am J Med Sci (2001) 1.10
Calmodulin-activated cyclic nucleotide phosphodiesterase from brain. Relationship of subunit structure to activity assessed by radiation inactivation. J Biol Chem (1981) 1.09
Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine. Proc Natl Acad Sci U S A (1988) 1.09
Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency. J Biol Chem (1997) 1.08
Hypertriglyceridaemia due to genetic defects in lipoprotein lipase and apolipoprotein C-II. J Intern Med (1992) 1.08
In vivo metabolism of a mutant apolipoprotein, apoA-IIowa, associated with hypoalphalipoproteinemia and hereditary systemic amyloidosis. J Lipid Res (1992) 1.08
Purification and characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase from chicken liver. FEBS Lett (1977) 1.08
cDNA cloning of human apoA-I: amino acid sequence of preproapoA-I. Biochem Biophys Res Commun (1983) 1.07
A deletion mutation in the ApoC-II gene (ApoC-II Nijmegen) of a patient with a deficiency of apolipoprotein C-II. J Biol Chem (1988) 1.07
In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II. J Lipid Res (1991) 1.06
Circulatory, plasma catecholamine, cortisol, lipid, and psychological responses to a real-life stress (third molar extractions): effects of diazepam sedation and of inclusion of epinephrine with the local anesthetic. Psychosom Med (1982) 1.06
Human apolipoprotein A-I and C-III genes reside in the p11----q13 region of chromosome 11. Biochem Biophys Res Commun (1984) 1.06
Nucleotide sequence and the encoded amino acids of human apolipoprotein A-I mRNA. Proc Natl Acad Sci U S A (1984) 1.06
Modulation of the enzymic activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by multiple kinase systems involving reversible phosphorylation: a review. Metabolism (1987) 1.06
Structural studies on rabbit muscle glycogen synthase. I. Subunit composition. J Biol Chem (1975) 1.06
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. J Clin Invest (1995) 1.05
Levels of lipoprotein Lp(a) decline with neomycin and niacin treatment. Atherosclerosis (1985) 1.05
Regulation and intracellular trafficking of the ABCA1 transporter. J Lipid Res (2001) 1.04
Amino acid sequence of human plasma apolipoprotein C-II from normal and hyperlipoproteinemic subjects. J Biol Chem (1984) 1.04
Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241. J Biol Chem (1992) 1.04
Isolation and characterization of the tryptic and cyanogen bromide peptides of apoLp-Gln-II (apoA-II), plasma high density apolipoprotein. J Biol Chem (1972) 1.04
Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase. J Biol Chem (1985) 1.03