A Aynsley-Green

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Avoidable factors contributing to death of children with head injury. BMJ 1990 4.33
2 Causes of fatal childhood accidents involving head injury in northern region, 1979-86. BMJ 1990 3.29
3 Observations on central and peripheral temperatures in the understanding and management of shock. Br J Surg 1969 3.11
4 What is a normal rate of weight gain in infancy? Acta Paediatr 1994 2.95
5 A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene. Nat Genet 2000 2.87
6 Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds. Pediatrics 2000 2.73
7 Measuring exposure to injury risk in schoolchildren aged 11-14. BMJ 1994 2.52
8 Breast vs bottle: endocrine responses are different with formula feeding. Lancet 1980 2.52
9 Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat Med 1996 2.40
10 Nesidioblastosis of the pancreas: definition of the syndrome and the management of the severe neonatal hyperinsulinaemic hypoglycaemia. Arch Dis Child 1981 2.36
11 Comparison of the use of Tanner and Whitehouse, NCHS, and Cambridge standards in infancy. Arch Dis Child 1993 2.30
12 Unethical age assessment. Br Dent J 2009 2.25
13 Neural dysfunction during hypoglycaemia. Arch Dis Child 1988 2.19
14 Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion. J Clin Invest 2001 2.01
15 Annual incidence of unintentional injury among 54,000 children. Inj Prev 1996 1.91
16 Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. Lancet 1987 1.78
17 Patterns of metabolic adaptation for preterm and term infants in the first neonatal week. Arch Dis Child 1992 1.73
18 Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor. N Engl J Med 1997 1.55
19 Hypoglycemia in infancy: the need for a rational definition. A Ciba Foundation discussion meeting. Pediatrics 1990 1.52
20 Lymphocyte subpopulations in the blood of newborn infants. Clin Exp Immunol 1974 1.48
21 Gut regulatory peptides and intestinal permeability in acute infantile gastroenteritis. Arch Dis Child 1992 1.46
22 Neonatal hypoglycaemia--the controversy regarding definition. Arch Dis Child 1988 1.44
23 Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. Lancet 1987 1.43
24 Plasma motilin, gastrin, and enteroglucagon and feeding in the human newborn. Arch Dis Child 1980 1.42
25 p57(KIP2) expression in normal islet cells and in hyperinsulinism of infancy. Diabetes 2001 1.42
26 Effect of deprivation on weight gain in infancy. Acta Paediatr 1994 1.40
27 Use of central and peripheral temperature measurements in care of the critically ill child. Arch Dis Child 1974 1.38
28 Management of hyperinsulinism in infancy and childhood. Ann Med 2000 1.33
29 Metabolic and endocrine events at the time of the first feed of human milk in preterm and term infants. Arch Dis Child 1978 1.32
30 Development of gut hormone responses to feeding in neonates. Arch Dis Child 1980 1.24
31 Gut hormones and 'minimal enteral feeding'. Acta Paediatr Scand 1986 1.23
32 Metabolic and endocrine responses to a milk feed in six-day-old term infants: differences between breast and cow's milk formula feeding. Acta Paediatr Scand 1981 1.23
33 Effect of somatostatin infusion on intermediary metabolism and entero-insular hormone release in infants with hyperinsulinaemic hypoglycaemia. Acta Paediatr Scand 1981 1.20
34 Does halothane anaesthesia decrease the metabolic and endocrine stress responses of newborn infants undergoing operation? Br Med J (Clin Res Ed) 1988 1.16
35 Non-invasive assessment of intraluminal lipolysis using a 13CO2 breath test. Arch Dis Child 1990 1.16
36 Measuring the severity of surgical stress in newborn infants. J Pediatr Surg 1988 1.16
37 Ionic control of beta cell function in nesidioblastosis. A possible therapeutic role for calcium channel blockade. Arch Dis Child 1996 1.14
38 Hormonal and metabolic response to hypoglycaemia in small for gestational age infants. Arch Dis Child 1993 1.12
39 Postnatal surges in plasma gut hormones in term and preterm infants. Biol Neonate 1982 1.12
40 Mutations in the liver glycogen synthase gene in children with hypoglycemia due to glycogen storage disease type 0. J Clin Invest 1998 1.11
41 Fatal lactic acidosis in infancy with a defect of complex III of the respiratory chain. Pediatr Res 1989 1.08
42 Evaluation of fasts for investigating hypoglycaemia or suspected metabolic disease. Arch Dis Child 1996 1.08
43 Postnatal development of multiple opioid receptors in the spinal cord and development of spinal morphine analgesia. Brain Res Dev Brain Res 1998 1.06
44 Anaesthesia and insulin secretion: the effects of diethyl ether, halothane, pentobarbitone sodium and ketamine hydrochloride on intravenous glucose tolerance and insulin secretion in the rat. Diabetologia 1973 1.05
45 Hepatic glycogen synthetase deficiency. Definition of syndrome from metabolic and enzyme studies on a 9-year-old girl. Arch Dis Child 1977 1.03
46 The role of pancreatic insulin secretion in neonatal glucoregulation. I. Healthy term and preterm infants. Arch Dis Child 1993 1.03
47 Can the human neonate mount an endocrine and metabolic response to surgery? J Pediatr Surg 1985 1.03
48 The role of pancreatic insulin secretion in neonatal glucoregulation. II. Infants with disordered blood glucose homoeostasis. Arch Dis Child 1993 1.02
49 Studies on the hormonal regulation of fuel metabolism in the human newborn infant undergoing anaesthesia and surgery. Horm Res 1985 1.01
50 Interrelation of the therapeutic effects of growth hormone and testosterone on growth in hypopituitarism. J Pediatr 1976 1.00
51 Endocrine and metabolic response in the human newborn to first feed of breast milk. Arch Dis Child 1977 1.00
52 Hypoketotic hypofattyacidaemic hypoinsulinaemic hypoglycaemia in a child with hemihypertrophy? A new syndrome. Horm Res 2004 1.00
53 Nesidioblastosis of the pancreas in infancy. Dev Med Child Neurol 1981 0.98
54 Management of childhood pyrexia using central and peripheral temperature recordings. Lancet 1973 0.97
55 Cerebral blood flow and metabolism in children with severe head injury. Part 1: Relation to age, Glasgow coma score, outcome, intracranial pressure, and time after injury. J Neurol Neurosurg Psychiatry 1995 0.97
56 Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy. J Biol Chem 1999 0.96
57 Prevention and management of neonatal hypoglycaemia. Arch Dis Child Fetal Neonatal Ed 1994 0.96
58 Therapy for persistent hyperinsulinemic hypoglycemia of infancy. Understanding the responsiveness of beta cells to diazoxide and somatostatin. J Clin Invest 1997 0.95
59 A new simple screening method for the diagnosis of medium chain acyl-CoA dehydrogenase deficiency. Clin Chim Acta 1987 0.95
60 Congenital bilateral anorchia in childhood: a clinical, endocrine and therapeutic evaluation of twenty-one cases. Clin Endocrinol (Oxf) 1976 0.95
61 Elevated plasma peptide YY in human neonates and infants. Pediatr Res 1986 0.94
62 Metabolic and endocrine consequences of depriving preterm infants of enteral nutrition. Acta Paediatr Scand 1983 0.93
63 Neonates with symptomatic hyperinsulinemic hypoglycemia generate inappropriately low serum cortisol counterregulatory hormonal responses. J Clin Endocrinol Metab 2003 0.92
64 Ketogenic diets in the treatment of epilepsy: short-term clinical effects. Dev Med Child Neurol 1989 0.92
65 Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways. Diabetes 2001 0.92
66 Endocrine studies in Fanconi's anaemia. Report of 4 cases. Arch Dis Child 1978 0.92
67 Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis). FEBS Lett 1997 0.91
68 Glucose homeostasis in adulthood and in pregnancy in a patient with hepatic glycogen synthetase deficiency. Br J Obstet Gynaecol 1995 0.90
69 Hyperinsulinaemic hypoglycaemia in infancy and childhood: a practical approach to diagnosis and medical treatment based on experience of 18 cases. Acta Paediatr Hung 1984 0.90
70 The measurement of carnitine and acyl-carnitines: application to the investigation of patients with suspected inherited disorders of mitochondrial fatty acid oxidation. Clin Chim Acta 1992 0.89
71 The metabolic and endocrine milieu of the human fetus and mother at 18-21 weeks of gestation. I. Plasma amino acid concentrations. Pediatr Res 1985 0.89
72 The effects of anesthesia and surgery on metabolic homeostasis in infancy and childhood. J Pediatr Surg 1990 0.89
73 Persistent pulmonary hypertension and abnormal prostaglandin E levels in preterm infants after maternal treatment with naproxen. Arch Dis Child 1979 0.89
74 Medium chain acyl-CoA dehydrogenase deficiency caused by a deletion of exons 11 and 12. Hum Mol Genet 1995 0.88
75 Iatrogenic hyperinsulinism at birth. Lancet 1980 0.88
76 Feeding and the development of enteroinsular hormone secretion in the preterm infant: effects of continuous gastric infusions of human milk compared with intermittent boluses. Acta Paediatr Scand 1982 0.88
77 Air temperature recordings in infant incubators. Arch Dis Child 1975 0.88
78 Averted sudden neonatal death due to pancreatic nesidioblastosis. Lancet 1978 0.88
79 Plasma proinsulin and C-peptide concentrations in children with hyperinsulinaemic hypoglycaemia. Acta Paediatr Scand 1984 0.87
80 Management of children with head injuries in district general hospitals. Arch Dis Child 1988 0.87
81 Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner. J Biol Chem 2000 0.86
82 Effects of feeding regimen on blood glucose levels and plasma concentrations of pancreatic hormones and gut regulatory peptides at 9 months of age: comparison between infants fed with milk formula and infants exclusively breast-fed from birth. J Pediatr Gastroenterol Nutr 1988 0.86
83 The effect of feeds of differing composition on entero-insular hormone secretion in the first hours of life in human neonates. Acta Paediatr Scand 1979 0.86
84 Neonatal blood glucose concentrations: metabolic effects of intravenous glucagon and intragastric medium chain triglyceride. Arch Dis Child 1993 0.86
85 Hyperinsulinism in infancy and childhood. Ergeb Inn Med Kinderheilkd 1984 0.85
86 Gonadal function after 12-Gy testicular irradiation in childhood acute lymphoblastic leukaemia. Med Pediatr Oncol 1990 0.85
87 Hypoglycaemia in infants and children. Clin Endocrinol Metab 1982 0.85
88 Patterns of the metabolic and endocrine stress response to surgery and medical illness in infancy and childhood. Crit Care Med 1993 0.84
89 Immediate metabolic response to a low dose of insulin in children presenting with diabetes. Arch Dis Child 1975 0.84
90 The dietary treatment of hepatic glycogen synthetase deficiency. Helv Paediatr Acta 1977 0.84
91 Isolated ACTH deficiency. Metabolic and endocrine studies in a 7-year-old boy. Arch Dis Child 1978 0.84
92 Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA). Eur J Pediatr 1983 0.84
93 Neonatal hypoglycaemia--blood glucose monitoring and baby feeding. Midwifery 1993 0.84
94 Growth hormone enhances proinflammatory cytokine production by monocytes in whole blood. Growth Horm IGF Res 2003 0.84
95 The definition of hypoglycaemia. Baillieres Clin Endocrinol Metab 1993 0.83
96 Inherited defects of mitochondrial fatty acid oxidation. Biochem Soc Trans 1988 0.83
97 Isolated glucocorticoid deficiency: metabolic and endocrine studies in a 5-year-old boy. Eur J Pediatr 1985 0.83
98 Metabolic and endocrine interrelations in the human fetus and neonate. Am J Clin Nutr 1985 0.83
99 Metabolic effects of three ketogenic diets in the treatment of severe epilepsy. Dev Med Child Neurol 1989 0.82
100 Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels. Endocr Relat Cancer 2002 0.82
101 A practical method of serial bedside measurement of cerebral blood flow and metabolism during neurointensive care. Arch Dis Child 1991 0.82
102 Immunological studies in the neonate of a mother with Addison's disease and diabetes mellitus. Clin Exp Immunol 1977 0.82
103 Management of secondary diabetes mellitus after total pancreatectomy in infancy. Arch Dis Child 1984 0.82
104 Asymptomatic hepatic glycogen-synthetase deficiency. Lancet 1978 0.82
105 Spontaneous hypoglycemia in childhood is accompanied by paradoxically low serum growth hormone and appropriate cortisol counterregulatory hormonal responses. J Clin Endocrinol Metab 2003 0.82
106 Plasma secretin in neonates. Acta Paediatr Scand 1980 0.82
107 Fetal distress, meconium, and motilin. Lancet 1979 0.81
108 The role of regulatory peptides in postnatal metabolic adaptation. Acta Endocrinol Suppl (Copenh) 1986 0.81
109 The endocrinology of feeding in the newborn. Baillieres Clin Endocrinol Metab 1989 0.80
110 Hepatic glycogen synthetase deficiency not expressed in cultured skin fibroblasts. Clin Chim Acta 1983 0.80
111 The effect of severe head injury on whole body energy expenditure and its possible hormonal mediators in children. Pediatr Res 1995 0.80
112 Impaired ketogenesis in fructose-1,6-bisphosphatase deficiency: a pitfall in the investigation of hypoglycaemia. J Inherit Metab Dis 1995 0.80
113 Fatal lactic acidosis due to deficiency of E1 component of the pyruvate dehydrogenase complex. J Inherit Metab Dis 1988 0.80
114 Severe transient neonatal hyperinsulinism associated with hyperlactataemia in non-asphyxiated infants. J Pediatr Endocrinol Metab 2004 0.80
115 Characterization of ion channels in stimulus-secretion coupling in pancreatic islets. Digestion 1997 0.79
116 The ontogeny of the metabolic and endocrine stress response in the human fetus, neonate and child. Intensive Care Med 1989 0.79
117 Human forearm arteriovenous differences of carnitine, short-chain acylcarnitine and long-chain acylcarnitine. Clin Sci (Lond) 1989 0.79
118 The steroid hormonal milieu of the undisturbed human fetus and mother at 16-20 weeks gestation. J Clin Endocrinol Metab 1991 0.79
119 Dichloroacetate in the treatment of congenital lactic acidosis. J Inherit Metab Dis 1984 0.79
120 Plasma neurotensin in term and preterm neonates. Acta Paediatr Scand 1981 0.79
121 Pain and stress in infancy and childhood--where to now? Paediatr Anaesth 1996 0.79
122 Hormones and postnatal adaptation to enteral nutrition. J Pediatr Gastroenterol Nutr 1983 0.79
123 Diuretics and carbohydrate metabolism: the effects of furosemide and amiloride on blood glucose, plasma insulin and cations in the rat. Diabetologia 1973 0.78
124 Hyperinsulinism in infancy: understanding the pathophysiology. Int J Biochem Cell Biol 2003 0.78
125 Tolerance to somatostatin analogue in a preterm infant with islet cell dysregulation syndrome. Arch Dis Child 1991 0.78
126 Michael Parkin--an international paediatrician. Arch Dis Child 1990 0.78
127 Hyperinsulinaemic hypoglycaemia in infancy and childhood--resolving the enigma. J Pediatr Endocrinol Metab 2004 0.78
128 In vivo stimulation of insulin secretion by guanidine derivatives in the rat. Horm Metab Res 1974 0.78
129 Letter: Enhancement by chlorpromazine of hyperglycaemic action of diazoxide. Lancet 1975 0.78
130 Gut hormones and the first meals. Clin Sci (Lond) 1981 0.78
131 Circulating aldosterone levels are unexpectedly low in children with acute meningococcal disease. J Clin Endocrinol Metab 2004 0.78
132 Gastrointestinal and pancreatic hormones in the human fetus and mother at 18-21 weeks of gestation. Biol Neonate 1995 0.77
133 The control of the adaptation of the human neonate to postnatal nutrition. Acta Chir Scand Suppl 1981 0.77
134 Temperature response to severe head injury and the effect on body energy expenditure and cerebral oxygen consumption. Arch Dis Child 1995 0.77
135 Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y. Diabetes 2000 0.77
136 Hyperinsulinaemic hypoglycaemia in preterm neonates. Arch Dis Child Fetal Neonatal Ed 2004 0.77
137 Pain, anaesthesia, and babies. Lancet 1987 0.77
138 Congenital adrenal hyperplasia: management during critical illness. Arch Dis Child 2001 0.77
139 Plasma pancreatic polypeptide in the human neonate. Acta Paediatr Scand 1980 0.77
140 The effects of anesthesia and surgery on lymphocyte populations and function in infants and children. J Pediatr Surg 1989 0.76
141 Persistent hyperinsulinaemic hyperglycaemia of infancy-derived cells; implications for beta-cells that replicate in vitro. J Mol Endocrinol 2000 0.76
142 Encephalitis lethargica-like illness in a five-year-old. Dev Med Child Neurol 1991 0.76
143 Abnormalities of carbohydrate metabolism and of OCT gene function in the Rett syndrome. Brain Dev 1990 0.76
144 The metabolic and endocrine milieu of the human fetus at 18-21 weeks of gestation. II. Blood glucose, lactate, pyruvate and ketone body concentrations. Biol Neonate 1985 0.76
145 Raised cerebrospinal fluid glycerol concentration associated with use of dichloroacetate. Arch Dis Child 1998 0.75
146 Hunger behaviour contributes to early nutritional homeostasis. Acta Paediatr 1999 0.75
147 Massive pulmonary haemorrhage in the newborn infant. Arch Dis Child 1975 0.75
148 Neonatal hyperglycaemia after prolonged maternal treatment with diazoxide. Br Med J (Clin Res Ed) 1982 0.75
149 Changes in cerebral oxygen consumption are independent of changes in body oxygen consumption after severe head injury in childhood. J Neurol Neurosurg Psychiatry 1995 0.75
150 Letter: Coxsackie viruses and diabetes mellitus. Br Med J 1974 0.75
151 Neonatal brain growth during prolonged intravenous feeding. Arch Dis Child 1976 0.75
152 Hyperlactataemia during intravenous feeding in childhood. Arch Dis Child 1974 0.75
153 Letter: Tepid sponging in pyrexia. Br Med J 1975 0.75
154 Plasma somatomedin activity in an infant with Beckwith Wiedemann syndrome. Early Hum Dev 1978 0.75
155 Metabolic status of children with growth hormone insensitivity syndrome and responses to treatment with IGF-I. Horm Res 1998 0.75
156 Combined defect of long-chain 3-hydroxyacyl-CoA dehydrogenase, 2-enoyl-CoA hydratase and 3-oxoacyl-CoA thiolase. Prog Clin Biol Res 1992 0.75
157 Hormonal response to first feeding in neonates. J Pediatr 1978 0.75
158 Vasoactive intestinal peptide (VIP) in preterm and term neonates. Acta Paediatr Scand 1982 0.75
159 Growth hormone response to feeding in term and preterm neonates. Acta Paediatr Scand 1983 0.75
160 Proceedings: Use of central and peripheral temperature measurements in care of critically ill children. Arch Dis Child 1974 0.75
161 Screening for congenital hypothyroidism in the U.K. Lancet 1981 0.75
162 Hypoglycaemia in the infant and child. Baillieres Clin Endocrinol Metab 1993 0.75
163 Plasma hormone concentrations during enteral and parenteral nutrition in the human newborn. J Pediatr Gastroenterol Nutr 1983 0.75
164 Deficiency of 17-ketoreductase presenting before puberty. Horm Res 1993 0.75
165 Developmental aspects of gastric inhibitory polypeptide (GIP) and its possible role in the enteroinsular axis in neonates. Acta Paediatr Scand 1980 0.75
166 Earlier recognition of abnormal growth in children. Lancet 1981 0.75
167 Early pancreatectomy in neonatal hyperinsulinism. Pediatrics 1978 0.75
168 [Hypoglycemia in childhood]. Kinderarztl Prax 1993 0.75
169 Simultaneous occurrence of hypopituitarism and adrenal medullary insufficiency in a boy with hypoglycemia. Helv Paediatr Acta 1977 0.75
170 Feeding premature infants with human milk or preterm milk formula. Effects on postnatal growth and on circulating concentrations of intermediary metabolites, amino acids, and regulatory peptides. Biol Neonate 1985 0.75
171 The Kety Schmidt technique revisited: bedside measurement of cerebral blood flow and metabolism in children during and after cardiopulmonary bypass surgery. J Cardiothorac Anesth 1989 0.75
172 [Hypokalemia caused by hyperinsulinemia in infancy and childhood (based on 18 cases)]. Orv Hetil 1984 0.75
173 Blood cell glycogen synthetase activities in hepatic glycogen synthetase deficiency. Clin Chim Acta 1977 0.75
174 A comparison of height, weight and head circumference of primary school children living in deprived and non-deprived circumstances. Early Hum Dev 1992 0.75
175 Cytochrome oxidase deficiency: immunological studies of skeletal muscle mitochondrial fractions. J Neurol Sci 1988 0.75
176 Modified hormonal effects on fat metabolism after severe head injury in children. Pediatr Res 1996 0.75
177 Anesthesia in neonatal cardiac surgery. N Engl J Med 1992 0.75
178 Gut hormones in neonatal nesidioblastosis of the pancreas. Lancet 1981 0.75
179 The effect of ethanol on glucose production in phosphorylase b kinase deficiency. J Inherit Metab Dis 1989 0.75
180 Gut hormones in fetal distress. Lancet 1979 0.75
181 Glucose production rates in type 1 glycogen storage disease. J Inherit Metab Dis 1990 0.75
182 Restraining infants in cars. BMJ 1988 0.75
183 The importance of the guanidine group in the insulin-stimulatory effect of amiloride hydrochloride. Horm Metab Res 1973 0.75
184 Hypoglycaemia in classical maple syrup urine disease is not due to hyperinsulinism. J Inherit Metab Dis 1983 0.75
185 Serum-insulin or plasma-insulin? Lancet 1972 0.75
186 Tissue specific defect of complex I of the mitochondrial respiratory chain. Biochem Biophys Res Commun 1989 0.75