Published in J Med Chem on September 01, 1982
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Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system. Br J Cancer (1999) 2.34
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Computerized determination of growth kinetic curves and doubling times from cells in microculture. Anal Biochem (1990) 1.13
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Ring-substituted [1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum (II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma. J Med Chem (1988) 0.85
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Evaluation of the antitumour activity of coumarin in prostate cancer models. J Cancer Res Clin Oncol (1993) 0.82
Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice. J Mol Endocrinol (2004) 0.82
Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies. Breast Cancer Res Treat (1989) 0.81
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Estrogenic regulation of clusterin mRNA in normal and malignant endometrial tissue. Int J Cancer (1998) 0.81
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Inhibition of metastasis by cicaprost in rats with established SMT2A mammary carcinoma growth. Cancer Detect Prev (1997) 0.80
The prostacyclin analogue cicaprost inhibits metastasis of tumours of R 3327 MAT Lu prostate carcinoma and SMT 2A mammary carcinoma. J Cancer Res Clin Oncol (1992) 0.80
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Nonsteroidal antiestrogens and partial estrogens with prostatic tumor inhibiting activity. J Cancer Res Clin Oncol (1986) 0.80
Progesterone antagonists: tumor-inhibiting potential and mechanism of action. J Steroid Biochem Mol Biol (1992) 0.79
Effect of growth factors on estrogen receptor mediated gene expression. J Steroid Biochem Mol Biol (1996) 0.79
Cicaprost inhibits metastases of animal tumors. Prostaglandins (1991) 0.79
Chromatographic analysis of the new antiestrogen zindoxifene and its metabolites in biological material. J Chromatogr (1987) 0.79
Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part II--The antileukemic effect. Arch Pharm (Weinheim) (1989) 0.79
Antitumour activity of coumarin and 7-hydroxycoumarin against 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinomas. J Cancer Res Clin Oncol (1994) 0.79
Antiestrogenic activities of 3,8-dihydroxy-6,11-dihydrobenzo[a]carbazoles with sulfur-containing side chains. Arch Pharm (Weinheim) (2000) 0.79
The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors. Eur J Cancer Clin Oncol (1985) 0.79
Enhancement of the antitumor efficacy of the antiprogestin, onapristone, by combination with the antiestrogen, ICI 164384. J Cancer Res Clin Oncol (1994) 0.79
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Betacellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro. Mol Cell Endocrinol (2008) 0.78
Growth-stimulating effect of adrenal androgens on the R3327 Dunning prostatic carcinoma. Urol Res (1991) 0.78
Platinum complexes with binding affinity for the estrogen receptor. J Med Chem (1988) 0.78
Human fetal pancreas transplants in nu/nu mice. Lancet (1977) 0.78
Effect of the new potent LHRH antagonist antide. J Steroid Biochem Mol Biol (1990) 0.78
Effect of zindoxifene on experimental prostatic tumours of the rat. J Cancer Res Clin Oncol (1991) 0.78
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Different response of murine and human mammary tumour models to a series of diastereoisomeric [1,2-bis(difluorophenyl) ethylenediamine]dichloroplatinum(II) complexes. J Cancer Res Clin Oncol (1991) 0.78
Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Arch Pharm (Weinheim) (1992) 0.78
1-Benzyl-2-phenylindole- and 1,2-diphenylindole-based antiestrogens. Estimation of agonist and antagonist activities in transfection assays. J Steroid Biochem Mol Biol (1998) 0.78
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Stromal expression of tenascin is inversely correlated to epithelial differentiation of hormone dependent tissues. J Steroid Biochem Mol Biol (1994) 0.78
[The mode of local anesthetic action of cinchocaine homologues]. Arzneimittelforschung (1970) 0.78
A rapid luciferase transfection assay for transcription activation effects and stability control of estrogenic drugs in cell cultures. J Cancer Res Clin Oncol (1994) 0.78
Progesterone receptor repression by estrogens in rat uterine epithelial cells. J Steroid Biochem Mol Biol (1998) 0.77
Human mammary cancers in nu/nu-mice. A model for testing in research and clinic. Klin Wochenschr (1977) 0.77
Dunning R3327-G prostate carcinoma of the rat: an appropriate model for drug evaluation. J Cancer Res Clin Oncol (1992) 0.77
Dissociation of estrogenic and cytotoxic properties of an estrogen receptor-binding platinum complex in human breast cancer cell lines. Cancer Res (1991) 0.77
Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part I--The antibacterial effect. Arch Pharm (Weinheim) (1989) 0.77
Efficacy of Cicaprost on metastasis in advanced tumor disease. Adv Exp Med Biol (1997) 0.77
Benzylamines: synthesis and evaluation of antimycobacterial properties. J Med Chem (1984) 0.77
The antitumor potency of progesterone antagonists is due to their differentiation potential. J Steroid Biochem Mol Biol (1992) 0.77
Novel antibodies directed against the extracellular domain of the human VEGF-receptor type II. Hybridoma (1997) 0.77
The rat endometrial adenocarcinoma cell line RUCA-I: a novel hormone-responsive in vivo/in vitro tumor model. J Steroid Biochem Mol Biol (1996) 0.77
[meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II), a new drug not only parenterally but also orally active in the therapy of breast and prostate cancer. J Cancer Res Clin Oncol (1993) 0.77
Mammary tumor inhibiting [1,2-bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes, III: Relationship between structure and estrogenic activity of the diamine ligands, their sulfatoplatinum(II) and diiodoplatinum(II) complexes. Arch Pharm (Weinheim) (1993) 0.76
[1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloro-platinum(II): an endocrine-active platinum complex with a specific prostatic tumor-inhibiting activity. Prostate (1989) 0.76
Involvement of the adrenal glands in the prolactin rise induced in the female rat by an antiprogestin, onapristone. J Steroid Biochem Mol Biol (1992) 0.76
Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)-ethylenediamine][cyclobutane-1,1- dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. J Cancer Res Clin Oncol (1998) 0.76
A multistage process for computing virtual dipolar sources of EEG discharges from surface information. IEEE Trans Biomed Eng (1972) 0.76
Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study. Br J Cancer (1990) 0.76
N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity. J Med Chem (1982) 0.76
Catechol estrogens of the 1,1,2-triphenylbut-1-ene type: relationship between structure, estradiol receptor affinity, estrogenic and antiestrogenic properties, and mammary tumor inhibiting activities. J Med Chem (1986) 0.76
Blood flow and oxygen consumption rates of human gynecological tumors xenografted into rnu/rnu-rats. Strahlenther Onkol (1989) 0.76
Tumor metastasis inhibition with the prostacyclin analogue cicaprost depends on discontinuous plasma peak levels. Prostaglandins Leukot Essent Fatty Acids (1998) 0.76
Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours. J Cancer Res Clin Oncol (1993) 0.76