Published in Exp Cell Res on March 01, 1983
Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes. J Cell Biol (1990) 2.84
Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine. J Cell Biol (1991) 1.36
Intracellular vesicle acidification promotes maturation of infectious poliovirus particles. PLoS Pathog (2012) 1.08
Psychosine-induced alterations in peroxisomes of twitcher mouse liver. Arch Biochem Biophys (2008) 0.82
2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation. Viruses (2017) 0.75
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell (1985) 11.63
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J (1999) 10.82
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity (1996) 8.27
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer (1998) 5.40
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. EMBO J (1996) 5.24
Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1982) 5.04
Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A (1999) 4.62
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins. J Exp Med (1987) 4.53
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination. EMBO J (1997) 4.01
A model for replication repair in mammalian cells. J Mol Biol (1976) 3.78
Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection. Infect Immun (1988) 3.70
Glycogen-Storage Disease: Thesaurismosis Glycogenica (von Gierke). Am J Pathol (1934) 3.49
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas. Nat Genet (1998) 3.38
Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice. Proc Natl Acad Sci U S A (1994) 3.34
Revision of consensus sequence of human Alu repeats--a review. Gene (1987) 3.22
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J Biol Chem (1987) 3.20
The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells. Biochem Biophys Res Commun (1991) 3.04
Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. Proc Natl Acad Sci U S A (1985) 3.01
Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. Proc Natl Acad Sci U S A (1988) 2.99
Quantitative analysis of Epstein-Barr virus load by using a real-time PCR assay. J Clin Microbiol (1999) 2.95
Initiation of meiosis in yeast mutants defective in adenylate cyclase and cyclic AMP-dependent protein kinase. Cell (1983) 2.91
Calcium stores regulate the polarity and input specificity of synaptic modification. Nature (2000) 2.84
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Genetic analysis of the role of cAMP in yeast. Yeast (1985) 2.78
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Focused Assessment with Sonography for Trauma (FAST): results from an international consensus conference. J Trauma (1999) 2.71
Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. Biochemistry (1991) 2.66
Allelic variation at the VRN-1 promoter region in polyploid wheat. Theor Appl Genet (2004) 2.61
Control of cell division in Saccharomyces cerevisiae mutants defective in adenylate cyclase and cAMP-dependent protein kinase. Exp Cell Res (1983) 2.48
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J Cancer Res Clin Oncol (1992) 2.40
Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J Cell Biol (1982) 2.37
Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor. Proc Natl Acad Sci U S A (2000) 2.36
Daily walking combined with diet therapy is a useful means for obese NIDDM patients not only to reduce body weight but also to improve insulin sensitivity. Diabetes Care (1995) 2.33
Detection of hepatitis C virus by polymerase chain reaction and response to interferon-alpha therapy: relationship to genotypes of hepatitis C virus. Hepatology (1992) 2.31
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. J Exp Med (2000) 2.30
Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts. Clin Cancer Res (1998) 2.22
Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm. Cancer Res (2001) 2.22
Giant negative thermal expansion in magnetic nanocrystals. Nat Nanotechnol (2008) 2.14
Properties of gastric smooth muscles obtained from mice which lack inositol trisphosphate receptor. J Physiol (2000) 2.11
Identification of the structural gene and nonsense alleles for adenylate cyclase in Saccharomyces cerevisiae. J Bacteriol (1984) 2.09
Mercury and cadmium resistances mediated by the penicillinase plasmid in Staphylococcus aureus. J Bacteriol (1974) 2.09
Changes in gastric acid secretion assayed by endoscopic gastrin test before and after Helicobacter pylori eradication. Gut (2000) 2.06
Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo. J Immunol (1994) 2.05
Cyclic AMP may not be involved in catabolite repression in Saccharomyes cerevisiae: evidence from mutants capable of utilizing it as an adenine source. J Bacteriol (1982) 2.05
Heat shock response of Saccharomyces cerevisiae mutants altered in cyclic AMP-dependent protein phosphorylation. Mol Cell Biol (1987) 2.05
Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein. J Exp Med (1992) 2.05
Peptide sequences for sucrose splitting and glucan binding within Streptococcus sobrinus glucosyltransferase (water-insoluble glucan synthetase). J Bacteriol (1991) 2.05
Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. Int J Oral Maxillofac Surg (2005) 2.02
The fine structure of the horizontal cells in some vertebrate retinae. Cold Spring Harb Symp Quant Biol (1965) 1.98
Visualization of substrate binding and translocation by the ATP-dependent protease, ClpXP. Mol Cell (2000) 1.98
Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J Clin Invest (1995) 1.95
Abdominal ultrasonography for the diagnosis of strangulation in small bowel obstruction. Br J Surg (1994) 1.95
Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease. Nat Genet (2001) 1.93
High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene. Nature (1995) 1.91
A novel phosphodiesterase from cultured tobacco cells. Biochemistry (1976) 1.90
The metabolic topography of parkinsonism. J Cereb Blood Flow Metab (1994) 1.89
Immunohistochemical localization of gamma-enolase in normal human tissues other than nervous and neuroendocrine tissues. Lab Invest (1985) 1.89
Nuclear magnetic resonance study of antibodies: a multinuclear approach. Methods Enzymol (1994) 1.85
gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family. J Biol Chem (1995) 1.83
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet (2001) 1.81
X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts. Clin Cancer Res (1999) 1.81
Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor. J Virol (1994) 1.80
A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy. J Pathol (2008) 1.78
Expression of fas/fas ligand (fasL) and its involvement in infiltrating lymphocytes in hepatocellular carcinoma (HCC). J Gastroenterol (2001) 1.77
Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes. Proc Natl Acad Sci U S A (1995) 1.76
Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis. Oncogene (2000) 1.76
Serum CYFRA 21-1 is one of the most reliable tumor markers for breast carcinoma. Cancer (2000) 1.73
Spontaneous rupture: a complication of benign mature teratomas of the mediastinum. AJR Am J Roentgenol (1998) 1.73
A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis. Eur Respir J (2010) 1.72
Sequence determination and functional analysis of the Akabane virus (family Bunyaviridae) L RNA segment. Arch Virol (2007) 1.72
Helicobacter pylori infection prevents erosive reflux oesophagitis by decreasing gastric acid secretion. Gut (2001) 1.71
Human serum beta-glucuronidase; its measurement and some of its properties. Clin Chim Acta (1967) 1.71
Notable diversity in peptide composition of murine H-2K and H-2D alloantigens. Biochemistry (1974) 1.70
Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis. Circ Res (2000) 1.70
Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol (1998) 1.70
Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice. EMBO J (2000) 1.70
Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function. Immunity (2000) 1.69
Changes in molecular forms of rat hepatic glutathione S-transferase during chemical hepatocarcinogenesis. Cancer Res (1984) 1.69
Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis. J Biol Chem (2001) 1.68
The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical hepatocarcinogenesis. Gan (1984) 1.68
H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent. Biochemistry (1973) 1.68
Structure of the planarian central nervous system (CNS) revealed by neuronal cell markers. Zoolog Sci (1998) 1.68
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination. Kidney Int (2000) 1.67
Usefulness and limitations of ultrasonography in the initial evaluation of blunt abdominal trauma. J Trauma (1998) 1.67
Frequency of heavy-metal resistance in bacteria from inpatients in Japan. Nature (1977) 1.66
Extrahepatic portosystemic venous shunt without portal hypertension. Intern Med (1997) 1.64
Changes in oropharyngeal airway and respiratory function during sleep after orthognathic surgery in patients with mandibular prognathism. Int J Oral Maxillofac Surg (2011) 1.64
Anomalous origin of the left main coronary artery from the right anterior aortic sinus: angiographic definition of anomalous course. Am J Cardiol (1985) 1.64
Macrophage activation by bacterial cell walls and related synthetic compounds. Infect Immun (1979) 1.63
Hyperfine structure of antiprotonic helium revealed by a laser-microwave-laser resonance method. Phys Rev Lett (2002) 1.62
Genetic and biochemical evidence that trehalase is a substrate of cAMP-dependent protein kinase in yeast. J Biol Chem (1983) 1.62
Linkage of mercury, cadmium, and arsenate and drug resistance in clinical isolates of Pseudomonas aeruginosa. Appl Environ Microbiol (1977) 1.61
Allelotype study of primary hepatocellular carcinoma. Cancer Res (1991) 1.61
Effective "short" double-balloon enteroscope for diagnostic and therapeutic ERCP in patients with altered gastrointestinal anatomy: a large case series. Endoscopy (2009) 1.61
Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo. Virology (1993) 1.60
Genetic control of the synthesis of repressible phosphatases in Neurospora crassa. Genetics (1971) 1.60
Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy. Cancer Res (2000) 1.60
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. J Clin Invest (2001) 1.60
Involvement of endothelin in the regulation of human vascular tonus. Potent vasoconstrictor effect and existence in endothelial cells. Circulation (1990) 1.59