Published in Prostaglandins on February 01, 1983
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature (1999) 4.32
Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. Prostaglandins (1980) 2.78
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest (1999) 2.54
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Marked improvement of the basophil activation test by detecting CD203c instead of CD63. Clin Exp Allergy (2003) 2.45
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature (1994) 2.37
Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia. J Biol Chem (1997) 2.35
Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor. Nat Med (1999) 2.26
Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein. J Biol Chem (1996) 1.91
Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides. Proc Natl Acad Sci U S A (1993) 1.87
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther (1994) 1.75
Rapid extraction of arachidonic acid metabolites from biological samples using octadecylsilyl silica. Methods Enzymol (1982) 1.59
Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood (2001) 1.59
Properties of leukotriene B4 20-hydroxylase from polymorphonuclear leukocytes. J Biol Chem (1984) 1.47
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice. Circulation (2001) 1.46
12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice. Circulation (2001) 1.45
Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc Natl Acad Sci U S A (1988) 1.45
Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc Natl Acad Sci U S A (1999) 1.42
Enzymes involved in the biosynthesis of leukotriene B4. J Biol Chem (1989) 1.32
cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. J Biol Chem (1994) 1.32
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J Clin Invest (1999) 1.30
IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1. Proc Natl Acad Sci U S A (2001) 1.26
5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice. Am J Physiol (1997) 1.20
Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase. Proc Natl Acad Sci U S A (1998) 1.13
The N-terminal "beta-barrel" domain of 5-lipoxygenase is essential for nuclear membrane translocation. J Biol Chem (2001) 1.10
12/15-lipoxygenase translocation enhances site-specific actin polymerization in macrophages phagocytosing apoptotic cells. J Biol Chem (2001) 1.08
Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis. Am J Physiol (1994) 1.02
cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase. J Biol Chem (1995) 0.99
The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization. J Biol Chem (2001) 0.98
Leukotriene binding, signaling, and analysis of HIV coreceptor function in mouse and human leukotriene B4 receptor-transfected cells. J Biol Chem (1999) 0.97
Determinants of 5-lipoxygenase nuclear localization using green fluorescent protein/5-lipoxygenase fusion proteins. J Biol Chem (1998) 0.96
Endotoxemia in transgenic mice overexpressing human glutathione peroxidases. Circ Res (2000) 0.96
5-oxo-ETE induces pulmonary eosinophilia in an integrin-dependent manner in Brown Norway rats. J Clin Invest (1998) 0.95
Metabolism of eicosapentaenoic acid by aorta: formation of a novel 13-hydroxylated prostaglandin. Biochim Biophys Acta (1985) 0.95
Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase expressed in a baculovirus/insect cell system. Eur J Biochem (1993) 0.95
Metabolism of linoleic acid by prostaglandin endoperoxide synthase from adult and fetal blood vessels. Biochim Biophys Acta (1983) 0.93
Lipoxin synthase activity of human platelet 12-lipoxygenase. Biochem J (1993) 0.92
Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase. Biochim Biophys Acta (1992) 0.92
Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. J Biol Chem (1998) 0.92
Release of prostaglandins and monohydroxy and trihydroxy metabolites of linoleic and arachidonic acids by adult and fetal aortae and ductus arteriosus. J Biol Chem (1985) 0.91
Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes. J Leukoc Biol (1996) 0.90
Human fibroblasts show expression of the leukotriene-A4-hydrolase gene, which is increased after simian-virus-40 transformation. Eur J Biochem (1990) 0.89
Molecular cloning and expression of mouse leukotriene A4 hydrolase cDNA. Biochem Biophys Res Commun (1991) 0.89
Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies. FASEB J (1993) 0.88
Reversed-phase high-pressure liquid chromatography of arachidonic acid metabolites formed by cyclooxygenase and lipoxygenases. Anal Biochem (1985) 0.87
Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice. J Invest Dermatol (1999) 0.86
Insight into prostaglandin, leukotriene, and other eicosanoid functions using mice with targeted gene disruptions. Prostaglandins Other Lipid Mediat (1999) 0.86
A molecular dipstick? Nat Struct Biol (1997) 0.85
Leukotrienes in bile during the early and the late airway responses after allergen challenge of sensitized rats. Am Rev Respir Dis (1993) 0.85
omega-Oxidation of prostaglandins by lung and liver microsomes. Changes in enzyme activity induced by pregnancy, pseudopregnancy, and progesterone treatment. J Biol Chem (1978) 0.85
Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences. Biochem J (2000) 0.85
Effects of protein deficiency on the metabolism of arachidonic acid by rat pleural polymorphonuclear leukocytes. Biochim Biophys Acta (1983) 0.84
Characterization of the murine epidermal 12/15-lipoxygenase. Prostaglandins Other Lipid Mediat (2001) 0.84
Localization of a prostaglandin F2alpha receptor in bovine Corpus luteum plasma membranes. Eur J Biochem (1976) 0.84
Inositol (1,4,5)trisphosphate metabolism and enhanced calcium mobilization in airway smooth muscle of hyperresponsive rats. Am J Respir Cell Mol Biol (2000) 0.83
Formation of 20-hydroxyprostaglandins by lungs of pregnant rabbits. J Biol Chem (1978) 0.83
Increased levels of monohydroxy metabolites of arachidonic acid and linoleic acid in LDL and aorta from atherosclerotic rabbits. Biochim Biophys Acta (1991) 0.83
High-pressure liquid chromatography of arachidonic acid metabolites. Adv Prostaglandin Thromboxane Leukot Res (1985) 0.83
Occurrence and properties of a prostaglandin F2alpha receptor in bovine corpora lutea. Eur J Biochem (1975) 0.82
The role of endogenous corticosterone in the late-phase response to allergen challenge in the brown Norway rat. Am J Respir Crit Care Med (1996) 0.82
Mechanism for the formation of dihydro metabolites of 12-hydroxyeicosanoids. Conversion of leukotriene B4 and 12-hydroxy-5,8,10,14-eicosatetraenoic acid to 12-oxo intermediates. J Biol Chem (1991) 0.82
Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. Biochim Biophys Acta (1979) 0.82
Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. Prostaglandins (1978) 0.81
Chromosomal localization of the human prostanoid receptor gene family. Genomics (1995) 0.81
Human prostanoid receptors: cloning and characterization. Adv Prostaglandin Thromboxane Leukot Res (1995) 0.81
The abacavir hypersensitivity reaction and interruptions in therapy. AIDS (2001) 0.81
Metabolism of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid and other hydroxylated fatty acids by the reductase pathway in porcine polymorphonuclear leukocytes. Biochemistry (1990) 0.81
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors. Biochem Pharmacol (2001) 0.81
Effects of dietary vitamin E on the biosynthesis of 5-lipoxygenase products by rat polymorphonuclear leukocytes (PMNL). Biochim Biophys Acta (1989) 0.81
Fluorescent Functional Recognition Sites through Molecular Imprinting. A Polymer-Based Fluorescent Chemosensor for Aqueous cAMP. Anal Chem (1998) 0.80
Metaplastic papillary tumor of the fallopian tube. Case report, immunohistochemical features, and review of the literature. Arch Pathol Lab Med (1989) 0.80
The metabolism of arachidonic and eicosapentaenoic acids in human neutrophils stimulated by A23187 and FMLP. J Cell Biochem (1989) 0.80
Some properties of a prostaglandin F2alpha receptor in corpora lutea. Adv Prostaglandin Thromboxane Res (1976) 0.80
Surgical resection of giant metastatic leiomyosarcoma of the heart. J Thorac Cardiovasc Surg (1987) 0.80
Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni. Prostaglandins Other Lipid Mediat (1998) 0.80
Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13. Cytogenet Cell Genet (1998) 0.80
The beta(2)-agonist salbutamol inhibits bronchoconstriction and leukotriene D(4) synthesis after dry gas hyperpnea in the guinea-pig. Pulm Pharmacol Ther (1999) 0.79
Endogenous prostaglandins modulate histamine-induced contraction in canine tracheal smooth muscle. J Appl Physiol (1985) (1985) 0.79
Letter: Prostaglandin-F2alpha receptor in human corpora lutea. Lancet (1974) 0.79
Conversion of leukotriene B4 to dihydro and 19-hydroxy metabolites by rat polymorphonuclear leukocytes. Biochem Biophys Res Commun (1987) 0.79
Formation of 6-oxoprostaglandin F1 alpha, 6,15-dioxoprostaglandin F1 alpha, and monohydroxyicosatetraenoic acids from arachidonic acid by fetal calf aorta and ductus arteriosus. J Biol Chem (1982) 0.79
Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. Am J Physiol (1997) 0.79
Prostaglandin F2alpha receptor in ovine corpora lutea. Eur J Biochem (1974) 0.79
Down-regulation of cyclooxygenase product generation by human peritoneal macrophages. Immunology (1992) 0.79
Leukocyte-type 12-lipoxygenase-deficient mice show impaired ischemic preconditioning-induced cardioprotection. Am J Physiol Heart Circ Physiol (2001) 0.78
Leukotriene A4, conversion to leukotriene B4 in human T-cell lines. Prostaglandins (1988) 0.78
Calcium/calmodulin-dependent conversion of 5-oxoeicosanoids to 6, 7-dihydro metabolites by a cytosolic olefin reductase in human neutrophils. J Biol Chem (1998) 0.78
Synthesis of prostaglandins and thromboxane B2 by cholesterol-fed rabbits. Arterioscler Thromb (1991) 0.78
Role of 'platelet-type' 12-lipoxygenase in skin carcinogenesis. Cancer Lett (2001) 0.78
Expression of porcine leukocyte 12-lipoxygenase in a baculovirus/insect cell system and its characterization. Arch Biochem Biophys (1994) 0.78
Inhibition of leukotriene B4 synthesis in human polymorphonuclear leukocytes after exposure to meningococcal lipopolysaccharide. Biochem Biophys Res Commun (1982) 0.78
Distribution of prostaglandin omega-hydroxylases in different tissues. Prostaglandins (1980) 0.78
Leukotriene A4-hydrolase, cloning of the human enzyme and tissue distribution in the rat. Adv Prostaglandin Thromboxane Leukot Res (1989) 0.78
Separation of unlabeled metabolites of arachidonic acid from their deuterium- and tritium-labeled analogs by argentation high-pressure liquid chromatography. Anal Biochem (1983) 0.78
Hyperpnea-induced bronchoconstriction is dependent on tachykinin-induced cysteinyl leukotriene synthesis. J Appl Physiol (1985) (1997) 0.77
Molecular cloning and amino acid sequence of human 5-lipoxygenase. Adv Prostaglandin Thromboxane Leukot Res (1989) 0.77
Molecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction. FEBS Lett (1992) 0.77
Novel transformations of HPETEs by cytochrome P450s. Ann N Y Acad Sci (1994) 0.77