Published in Biochem J on March 01, 1980
Comparison of bone and osteosarcoma adenylate cyclase. Effects of Mg2+, Ca2+, ATP4- and HATP3- in the assay mixture. Biochem J (1980) 0.82
Formycin 5'-triphosphate, a fluorescent analog of ATP, as a substrate for adenylate cyclase. Proc Natl Acad Sci U S A (1981) 0.77
A highly sensitive adenylate cyclase assay. Anal Biochem (1974) 20.13
Body size and tissue respiration. Biochim Biophys Acta (1950) 12.96
Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc Natl Acad Sci U S A (1973) 6.98
A difference in the architecture of the surface membrane of normal and virally transformed cells. Proc Natl Acad Sci U S A (1969) 6.03
Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells. Proc Natl Acad Sci U S A (1969) 5.39
Two distinct adenosine-sensitive sites on adenylate cyclase. Proc Natl Acad Sci U S A (1977) 3.89
Growth control and cyclic alterations of cyclic AMP in the cell cycle. Nat New Biol (1972) 2.93
5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells. Proc Natl Acad Sci U S A (1974) 2.63
Evidence for distinct guanine nucleotide sites in the regulation of the glucagon receptor and of adenylate cyclase activity. J Biol Chem (1977) 1.96
Adenyl cyclase. Adv Cyclic Nucleotide Res (1973) 1.69
A mutation in a rous sarcoma virus gene that controls adenosine 3',5'-monophosphate levels and transformation. J Biol Chem (1972) 1.56
Interrelationship between adenylate cyclase activity, adenosine 3':5' cyclic monophosphate phosphodiesterase activity, adenosine 3':5' cyclic monophosphate levels, and growth of cells in culture. Proc Natl Acad Sci U S A (1973) 1.28
Role of cyclic nucleotides in cell growth and differentiation. Physiol Rev (1976) 1.26
Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts. Nature (1974) 1.25
A simple, specific, radioisotopic assay for 5'-nucleotidase. Anal Biochem (1975) 1.24
Cyclic nucleotides in cultured cells. Adv Cyclic Nucleotide Res (1975) 1.22
Membrane proteins of uninfected and Rous sarcoma virus- transformed avian cells. J Virol (1973) 1.16
Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states. J Biol Chem (1977) 1.14
Role of cyclic nucleotides in cancer. Adv Cyclic Nucleotide Res (1974) 1.11
Effect of guanyl nucleotides on parathyroid hormone-responsive adenylate cyclase in chick kidney. J Endocrinol (1976) 1.10
Transformation of chick-embryo fibroblasts by wild-type and temperature-sensitive Rous sarcoma virus alters adenylate cyclase activity. Proc Natl Acad Sci U S A (1973) 1.08
Microviscosity in the surface membrane lipid layer of intact normal lymphocytes and leukemic cells. FEBS Lett (1974) 1.07
The content and metabolism of cyclic adenosine 3', 5'-monophosphate and cyclic guanosine 3', 5'-monophosphate in adenocarcinoma of the human colon. J Clin Invest (1976) 1.05
Hormone-receptor--adenylate cyclase interactions. FEBS Lett (1979) 1.04
Composition and synthesis of gangliosides in rat hepatocyte and hepatoma cell lines. J Biol Chem (1969) 0.99
Carbamyl phosphate: glucose phosphotransferase and glucose-6-phosphate phosphohydrolase of nuclear membrane. Interrelationships between membrane integrity, enzymic latency, and catalytic behavior. J Biol Chem (1975) 0.85
Adenylate cyclase enhancing factor from rat osteosarcoma cytosol. Biochem Biophys Res Commun (1978) 0.85
Comparison of bone and osteosarcoma adenylate cyclase. Effects of Mg2+, Ca2+, ATP4- and HATP3- in the assay mixture. Biochem J (1980) 0.82
Membranes from a transplantable osteogenic sarcoma responsive to parathyroid hormone and prostaglandins: regulation of adenylate cyclase and of hormone metabolism. J Endocrinol (1978) 0.81
Modulation of the distribution of plasma membrane intramembranous particles in contact-inhibited and transformed cells. Biochim Biophys Acta (1975) 0.80
Altered adenylate cyclase activity: its role in growth regulation and malignant transformation of fibroblasts. Adv Cyclic Nucleotide Res (1975) 0.79
The regulation of adenylate cyclase of the adrenal cortex. Mol Cell Endocrinol (1979) 0.79
Solubilization of adenylate cyclase from normal and Rous sarcoma-transformed chicken embryo fibroblasts. J Biol Chem (1976) 0.77
Adenosine 3',5'-cyclic monophosphate levels in x-ray-induced small-bowel adenocarcinoma in the rat. J Natl Cancer Inst (1976) 0.77
Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax (2008) 4.78
Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem (1991) 3.93
Role of osteoblasts in hormonal control of bone resorption--a hypothesis. Calcif Tissue Int (1981) 3.77
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J (1994) 3.60
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. Proc Natl Acad Sci U S A (1999) 2.66
Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J Clin Invest (1991) 2.63
Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma. Endocrinology (1980) 2.46
Angiogenic cytokines in patients with idiopathic interstitial pneumonia. Thorax (2004) 2.45
Streptococcal-host interactions. Structural and functional analysis of a Streptococcus sanguis receptor for a human salivary glycoprotein. J Biol Chem (1990) 2.40
Correlation between fibrinogen binding to human platelets and platelet aggregability. Blood (1980) 2.22
Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol (1992) 2.09
Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells. Exp Cell Res (1999) 2.06
Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties. Cancer Res (1987) 2.03
Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins. J Biol Chem (1989) 2.03
Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women. Bone (2001) 1.94
Breakers of advanced glycation end products restore large artery properties in experimental diabetes. Proc Natl Acad Sci U S A (1998) 1.92
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasis. Am J Med (1974) 1.86
Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells. J Clin Invest (1983) 1.84
M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase. Cell Death Differ (2003) 1.83
PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase. J Clin Invest (1998) 1.74
The detection of Epstein-Barr virus DNA in lung tissue from patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1999) 1.71
Pulmonary Langerhans' cell histiocytosis: radiologic resolution following smoking cessation. Chest (1999) 1.71
Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes. Proc Natl Acad Sci U S A (1993) 1.66
Expression of a calcium-mobilizing parathyroid hormone-like peptide in lactating mammary tissue. Science (1988) 1.64
Tissue specificity and developmental expression of rat osteopontin. Biochem Biophys Res Commun (1987) 1.61
Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts. J Clin Invest (1994) 1.57
High fatty acid content in rabbit serum is responsible for the differentiation of osteoblasts into adipocyte-like cells. J Bone Miner Res (1998) 1.56
Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and in vitro. Science (1987) 1.56
Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization. J Bone Miner Res (1990) 1.52
The effect of 1,25(OH)2D3 on alkaline phosphatase in osteoblastic osteosarcoma cells. J Biol Chem (1982) 1.45
Osteoclast formation, survival and morphology are highly dependent on exogenous cholesterol/lipoproteins. Cell Death Differ (2004) 1.44
Bacterial aggregating activity in human saliva: simultaneous determination of free and bound cells. Infect Immun (1979) 1.42
The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin). Biochem Biophys Res Commun (1983) 1.42
Bacterial aggregating activity in human saliva: comparisons of bacterial species and strains. Infect Immun (1981) 1.42
Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone. J Cell Sci (1999) 1.38
Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase. J Biol Chem (1999) 1.38
Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene. Biochem Biophys Res Commun (1989) 1.37
Human renal carcinoma expresses two messages encoding a parathyroid hormone-like peptide: evidence for the alternative splicing of a single-copy gene. Proc Natl Acad Sci U S A (1988) 1.36
A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc Natl Acad Sci U S A (2001) 1.35
Inhibition of osteoclastic bone resorption in vivo by echistatin, an "arginyl-glycyl-aspartyl" (RGD)-containing protein. Endocrinology (1993) 1.35
Prostaglandin receptor EP(4) mediates the bone anabolic effects of PGE(2). Mol Pharmacol (2001) 1.35
The effect of hemopoietic growth factors on the generation of osteoclast-like cells in mouse bone marrow cultures. Endocrinology (1990) 1.32
Inhibition of bone resorption by alendronate and risedronate does not require osteoclast apoptosis. Bone (2001) 1.32
Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor. J Biol Chem (1988) 1.32
Effect of alendronate on fracture healing and bone remodeling in dogs. J Orthop Res (1996) 1.31
Msx-2/Hox 8.1: a transcriptional regulator of the rat osteocalcin promoter. Mol Endocrinol (1994) 1.29
Pulmonary function in idiopathic pulmonary fibrosis and referral for lung transplantation. Am J Respir Crit Care Med (2001) 1.29
Saliva-mediated aggregation of Enterococcus faecalis transformed with a Streptococcus sanguis gene encoding the SSP-5 surface antigen. Infect Immun (1989) 1.29
Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones. Bone (1996) 1.26
Pattern of gene expression following rat tibial marrow ablation. J Bone Miner Res (1993) 1.25
Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3. Biochemistry (1988) 1.24
Type beta transforming growth factor (TGF beta) regulation of alkaline phosphatase expression and other phenotype-related mRNAs in osteoblastic rat osteosarcoma cells. J Cell Physiol (1987) 1.22
Post-transplantation survival of cystic fibrosis patients infected with Pseudomonas cepacia. Lancet (1994) 1.22
Integrins and signaling in osteoclast function. Matrix Biol (2000) 1.21
Increased activity of insulin-like growth factor (IGF) in osteoblastic cells in the presence of growth hormone (GH): positive correlation with the presence of the GH-induced IGF-binding protein BP-3. Endocrinology (1990) 1.21
The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin. J Biol Chem (1997) 1.20
Glucocorticoid regulation of alkaline phosphatase in the osteoblastic osteosarcoma cell line ROS 17/2.8. Endocrinology (1985) 1.20
Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation. Bone (1989) 1.18
The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. J Biol Chem (2000) 1.17
Platelet membrane glycoproteins in thrombasthenia, Bernard-Soulier syndrome, and storage pool disease. J Lab Clin Med (1979) 1.17
Hereditary giant platelet syndrome. Absence of collagen-induced coagulant activity and deficiency of factor-XI binding to platelets. Br J Haematol (1975) 1.16
Convergence of alpha(v)beta(3) integrin- and macrophage colony stimulating factor-mediated signals on phospholipase Cgamma in prefusion osteoclasts. J Cell Biol (2001) 1.15
Integrin function in osteoclasts. J Endocrinol (1997) 1.14
In vivo effects of bisphosphonates on the osteoclast mevalonate pathway. Endocrinology (2000) 1.14
Opposing effects of fibroblast growth factor and pertussis toxin on alkaline phosphatase, osteopontin, osteocalcin, and type I collagen mRNA levels in ROS 17/2.8 cells. J Biol Chem (1989) 1.14
Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate. Proc Natl Acad Sci U S A (1996) 1.14
Evidence for preferential effects of parathyroid hormone, calcitonin and adenosine on bone and periosteum. Endocrinology (1977) 1.13
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats. Eur Respir J (2002) 1.13
Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation. Mol Pharmacol (2001) 1.12
Murine gammaherpes virus as a cofactor in the development of pulmonary fibrosis in bleomycin resistant mice. Eur Respir J (2002) 1.12
Echistatin inhibits the migration of murine prefusion osteoclasts and the formation of multinucleated osteoclast-like cells. Endocrinology (1998) 1.11
Structure and function of the B and D genes of the Actinobacillus actinomycetemcomitans leukotoxin complex. Microb Pathog (1991) 1.11
Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther (2000) 1.10
Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone. J Biol Chem (1999) 1.08
A computer graphics program system for protein structure representation. Nucleic Acids Res (1988) 1.07
Type-beta transforming growth factor inhibits proliferation and expression of alkaline phosphatase in murine osteoblast-like cells. Biochem Biophys Res Commun (1986) 1.07
PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation. Cell Motil Cytoskeleton (2000) 1.07
Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2. J Biol Chem (2000) 1.07
Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs. Mol Endocrinol (1994) 1.07
Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology (1989) 1.06
Viruses and idiopathic pulmonary fibrosis. Eur Respir J (1997) 1.05
Abnormal localisation and hyperclustering of (alpha)(V)(beta)(3) integrins and associated proteins in Src-deficient or tyrphostin A9-treated osteoclasts. J Cell Sci (2001) 1.05
Tyrosine phosphorylation of p130Cas is involved in actin organization in osteoclasts. J Biol Chem (1998) 1.04
cDNA cloning of alkaline phosphatase from rat osteosarcoma (ROS 17/2.8) cells. J Bone Miner Res (1987) 1.03
Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone. J Cell Biol (1989) 1.03
Lung function estimates in idiopathic pulmonary fibrosis: the potential for a simple classification. Thorax (2005) 1.03
Identification and immunological characterization of the domain of Actinobacillus actinomycetemcomitans leukotoxin that determines its specificity for human target cells. J Biol Chem (1994) 1.03
High lateral mobility of endogenous and transfected alkaline phosphatase: a phosphatidylinositol-anchored membrane protein. J Cell Biol (1987) 1.02
Membrane changes during cartilage maturation. Increase in 5'-nucleotidase and decrease in adenosine inhibition of adenylate cyclase. J Cell Biol (1977) 1.02
Bone histomorphometry in adult patients with cystic fibrosis. Chest (2000) 1.01
Biphasic effects of transforming growth factor-beta on the production of osteoclast-like cells in mouse bone marrow cultures: the role of prostaglandins in the generation of these cells. Endocrinology (1990) 1.01
Isolation and characterization of highly enriched, prefusion mouse osteoclastic cells. Exp Cell Res (1995) 1.01