W G Owen

Author PubWeight™ 109.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Proc Natl Acad Sci U S A 1981 3.88
2 Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 1982 3.51
3 The conversion of prothrombin to thrombin. I. Characterization of the reaction products formed during the activation of bovine prothrombin. J Biol Chem 1974 2.19
4 Functional characteristics of lateral interactions between rods in the retina of the snapping turtle. J Physiol 1976 2.11
5 Evidence for the formation of an ester between thrombin and heparin cofactor. Biochim Biophys Acta 1975 1.97
6 Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 1981 1.94
7 Antihemophilic factor: separation of an active fragment following dissociation by salts or detergents. Thromb Diath Haemorrh 1972 1.93
8 The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2. J Neurosci 1988 1.79
9 Iron-dependent self-assembly of recombinant yeast frataxin: implications for Friedreich ataxia. Am J Hum Genet 2000 1.73
10 Campylobacter pylori: clinical, histological, and serological studies. J Clin Pathol 1988 1.67
11 A polypeptide region of bovine prothrombin specific for binding to phospholipids. Proc Natl Acad Sci U S A 1973 1.65
12 Binding of human thrombin to cultured human endothelial cells. J Biol Chem 1979 1.56
13 Coupling between rod photoreceptors in a vertebrate retina. Nature 1976 1.55
14 Clearance of thrombin from circulation in rabbits by high-affinity binding sites on endothelium. Possible role in the inactivation of thrombin by antithrombin III. J Clin Invest 1980 1.51
15 A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin. Biochim Biophys Acta 1978 1.28
16 Binding of thrombin to cultured human endothelial cells. Nonequilibrium aspects. J Biol Chem 1980 1.24
17 Free calcium concentrations in bullfrog rods determined in the presence of multiple forms of Fura-2. Biophys J 1994 1.23
18 High-pass filtering of small signals by retinal rods. Ionic studies. Biophys J 1983 1.22
19 Dopamine D2 receptor-mediated modulation of rod-cone coupling in the Xenopus retina. J Comp Neurol 1998 1.20
20 High-pass filtering of small signals by the rod network in the retina of the toad, Bufo marinus. Biophys J 1983 1.17
21 Identification in vitro of an endothelial cell surface cofactor for antithrombin III. Parallel studies with isolated perfused rat hearts and microcarrier cultures of bovine endothelium. J Clin Invest 1982 1.16
22 Use of endothelium cultured on microcarriers as a model for the microcirculation. Lab Invest 1982 1.16
23 beta-Hydroxyaspartic acid or beta-hydroxyasparagine in bovine low density lipoprotein receptor and in bovine thrombomodulin. J Biol Chem 1988 1.16
24 The lethal multiple congenital anomaly syndrome of polydactyly, sex reversal, renal hypoplasia, and unilobular lungs. J Med Genet 1986 1.15
25 Tissue plasminogen activator release in vivo in response to vasoactive agents. Blood 1985 1.15
26 The pathology and mineral content of lungs in cases of mesothelioma in the United Kingdom in 1976. IARC Sci Publ 1980 1.12
27 The effect of bovine thrombomodulin on the specificity of bovine thrombin. J Biol Chem 1986 1.12
28 Strong T-transformation associated with a severe haemolytic reaction in a young infant transfused with packed red cells. Clin Lab Haematol 1981 1.11
29 The conversion of prothrombin to thrombin. II. Differentiation between thrombin- and factor Xa-catalyzed proteolyses. J Biol Chem 1974 1.10
30 Mesothelial tumors and exposure to asbestos dust. Ann N Y Acad Sci 1965 1.06
31 The generation of the late receptor potential: an excitation-inhibition phenomenon. Vision Res 1972 1.03
32 Cone dystrophy with dominant inheritance. Am J Ophthalmol 1974 1.03
33 Dynamic, spatially nonuniform calcium regulation in frog rods exposed to light. J Neurophysiol 1996 1.03
34 Ionic conductances in rod photoreceptors. Annu Rev Physiol 1987 1.01
35 Involvement of heparin chain length in the heparin-catalyzed inhibition of thrombin by antithrombin III. J Biol Chem 1984 1.01
36 Characterization of the lectin from the bulbs of Eranthis hyemalis (winter aconite) as an inhibitor of protein synthesis. J Biol Chem 1993 1.01
37 Light-dependent control of calcium in intact rods of the bullfrog Rana catesbeiana. J Neurophysiol 1996 1.00
38 Voltage gain of signal transfer from retinal rods to bipolar cells in the tiger salamander. J Physiol 1987 1.00
39 Atrial fibrillation and thrombosis: immunohistochemical differences between in situ and embolized thrombi. J Thromb Haemost 2004 1.00
40 Temporal filtering in retinal bipolar cells. Elements of an optimal computation? Biophys J 1990 1.00
41 Circulating microparticles and endogenous estrogen in newly menopausal women. Climacteric 2009 0.98
42 A plausible mechanism for prothrombin activation by factor Xa, factor Va, phospholipid, and calcium ions. J Biol Chem 1974 0.97
43 Receptive field of the retinal bipolar cell: a pharmacological study in the tiger salamander. J Neurophysiol 1996 0.97
44 Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom). Biochemistry 1980 0.97
45 Active-site-dependent, thrombin-induced release of adenine nucleotides from cultured human endothelial cells. Ann N Y Acad Sci 1981 0.96
46 Spatial organization of the bipolar cell's receptive field in the retina of the tiger salamander. J Physiol 1990 0.96
47 Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor. J Biol Chem 1980 0.95
48 The elastase-mediated pathway of fibrinolysis. Blood Coagul Fibrinolysis 1991 0.95
49 cAMP response element-binding protein monomers cooperatively assemble to form dimers on DNA. J Biol Chem 1998 0.94
50 A functional assay of protein C in human plasma. Blood 1984 0.94
51 The conversion of prothrombin to thrombin. V. The activation of prothrombin by factor Xa in the presence of phospholipid. J Biol Chem 1974 0.94
52 The discovery of thrombomodulin. J Thromb Haemost 2004 0.93
53 Fibrinogen, fibrin and crosslinking in aging arterial thrombi. Thromb Haemost 2000 0.93
54 Procoagulant activity, but not number, of microparticles increases with age and in individuals after a single venous thromboembolism. Thromb Res 2010 0.93
55 The action of thrombin on blood clotting factor V: conversion of factor V to a prothrombin-binding protein. Biochim Biophys Acta 1973 0.92
56 Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women. J Clin Endocrinol Metab 2001 0.91
57 Platelet characteristics associated with coronary artery disease. J Thromb Haemost 2003 0.91
58 An elastase-dependent pathway of plasminogen activation. Biochemistry 1989 0.90
59 ATP-sensitive K+ channels in a plasma membrane H+-ATPase mutant of the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1989 0.89
60 Macromolecular specificity determinants on thrombin for fibrinogen and thrombomodulin. J Biol Chem 1989 0.89
61 Linear transduction of natural stimuli by dark-adapted and light-adapted rods of the salamander, Ambystoma tigrinum. J Physiol 1997 0.89
62 Quantitative comparison of fibrin degradation with plasmin, miniplasmin, neurophil leukocyte elastase and cathepsin G. Thromb Haemost 1996 0.89
63 Porcine model of stent thrombosis: platelets are the primary component of acute stent closure. Cathet Cardiovasc Diagn 1996 0.89
64 The control of hemostasis. Role of endothelium in the regulation of inhibitory and catabolic pathways. Arch Pathol Lab Med 1982 0.89
65 Individual propensity for arterial thrombosis. Arterioscler Thromb Vasc Biol 1999 0.88
66 Fractionation and preliminary characterization of a low molecular weight bovine hepatic inhibitor of DNA synthesis in regenerating rat liver. Exp Cell Res 1979 0.88
67 Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons. Brain Res 1998 0.87
68 Reaction of antithrombin III with thrombin bound to the vascular endothelium. Analysis in a recirculating perfused rabbit heart preparation. J Biol Chem 1984 0.87
69 Gap junctions among the perikarya, dendrites, and axon terminals of the luminosity-type horizontal cell of the turtle retina. J Comp Neurol 1983 0.86
70 Dual effect of synthetic plasmin substrates on plasminogen activation. Biochim Biophys Acta 1995 0.86
71 Effects of bicarbonate versus HEPES buffering on measured properties of neurons in the salamander retina. Vis Neurosci 1998 0.85
72 High concentrations of active plasminogen activator inhibitor-1 in porcine coronary artery thrombi. Arterioscler Thromb Vasc Biol 1996 0.85
73 A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry. J Thromb Haemost 2007 0.83
74 Current-voltage relations in the rod photoreceptor network of the turtle retina. J Physiol 1980 0.83
75 Rapid dark adaptation in the frog rod. Vision Res 1973 0.81
76 Hirudin as a molecular probe for thrombin in vitro and during systemic coagulation in the pig. Proc Natl Acad Sci U S A 1993 0.81
77 Identification of a congenital dysthrombin, thrombin Quick. J Clin Invest 1980 0.81
78 Platelet plasminogen activator inhibitor: purification and characterization of interaction with plasminogen activators and activated protein C. Biochemistry 1989 0.81
79 Inhibition and reversal of platelet-rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition. J Thromb Haemost 2004 0.81
80 Evidence for an ester bond between thrombin and heparin cofactor. Thromb Haemost 1976 0.81
81 Denatured proteins as cofactors for plasminogen activation. Arch Biochem Biophys 1997 0.80
82 The affinities of procolipase and colipase for interfaces are regulated by lipids. Biophys J 1996 0.80
83 Tissue prothrombin. Universal distribution in smooth muscle. Arterioscler Thromb Vasc Biol 1997 0.80
84 Isolation of a heparin-like anticoagulant from the plasma of a patient with metastatic bladder carcinoma. Blood 1989 0.80
85 Insulin binding to microvascular endothelium of intact heart: a kinetic and morphometric analysis. Am J Physiol 1983 0.80
86 Detection of thrombin in human blood by ex-vivo hirudin. Thromb Res 1996 0.79
87 Prostacyclin release from cultured and ex vivo bovine vascular endothelium. Studies with thrombin, arachidonic acid, and ionophore A23187. Lab Invest 1981 0.79
88 Similar effects of carbachol and dopamine on neurons in the distal retina of the tiger salamander. Vis Neurosci 1995 0.79
89 Platelet responses to compound interactions with thrombin. Biochemistry 1999 0.79
90 Interaction of thrombin with the vascular endothelium in a recirculating Langendorff rabbit heart preparation. Ann N Y Acad Sci 1982 0.79
91 Effects of 2-amino-4-phosphonobutyric acid on cells in the distal layers of the tiger salamander's retina. J Physiol 1992 0.79
92 Binding of iron by factor IX. Possible role for beta-hydroxyaspartic acid. J Biol Chem 1986 0.78
93 Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemia. Blood 1996 0.78
94 Persistent thrombin generation in humans during specific thrombin inhibition with hirudin. Circulation 1994 0.78
95 Facilitation of plasminogen activation by a plasmin substrate containing a lysyl residue. Thromb Haemost 1993 0.78
96 Myosin as cofactor and substrate in fibrinolysis. FEBS Lett 1997 0.77
97 Neutrophil proteases in plasminogen activation. Blood Coagul Fibrinolysis 1990 0.77
98 Endogenous antithrombin associated with microvascular endothelium. Quantitative analysis in perfused rat hearts. Biochemistry 1994 0.77
99 Fechtner syndrome: physiologic analysis of macrothrombocytopenia. Blood Coagul Fibrinolysis 2000 0.77
100 Antithrombotic action of endogenous porcine protein C activated with a latent porcine thrombin preparation. Thromb Haemost 1995 0.76
101 The suppression-recovery effect in the frog photoreceptor. Vision Res 1973 0.76
102 Spatio-temporal integration in the human peripheral retina. Vision Res 1972 0.75
103 A factor from endothelium facilitates activation of plasminogen by tissue plasminogen activator. Enzyme 1988 0.75
104 Characterization of the catalytic defect in the dysthrombin, Thrombin Quick. J Biol Chem 1987 0.75
105 Identity of bovine platelet aggregation factor and ristocetin-Willebrand factor. Thromb Res 1978 0.75
106 Facilitation of plasminogen activation by denatured prothrombin. Thromb Res 1999 0.75
107 6-aminohexanoate and chloride ion in the activation by urokinase of porcine plasminogens. Biochim Biophys Acta 1990 0.75
108 Effect of oral contraceptive use on platelet prothrombin converting (platelet factor 3) activity. Thromb Res 1979 0.75
109 Reversibility of platelet thrombosis in vivo. Quantitative analysis in porcine carotid arteries. Thromb Haemost 1996 0.75
110 Preparation and properties of water-insoluble thrombin. Am J Physiol 1971 0.75
111 Interaction of factor Xa with heparin does not contribute to the inhibition of factor Xa by antithrombin III-heparin. Biochemistry 1990 0.75
112 Esterolytic method for determination of heparin in plasma. Clin Chem 1981 0.75
113 Effect of heparin on the extent of inhibition of thrombin by heparin cofactor. Biochim Biophys Acta 1977 0.75
114 Requirement of zymogen modification for activation of porcine plasminogen. Biochemistry 1992 0.75
115 A sensitive and specific assay for plasminogen activators. Thromb Res 1985 0.75