Published in J Med Chem on January 01, 1980
MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities. Antimicrob Agents Chemother (1980) 9.02
The mechanism of action of fosfomycin (phosphonomycin). Ann N Y Acad Sci (1974) 7.21
Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase. Antimicrob Agents Chemother (1982) 5.83
Thienamycin: development of imipenen-cilastatin. J Antimicrob Chemother (1983) 5.52
Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis. Antimicrob Agents Chemother (1997) 4.87
Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties. J Antibiot (Tokyo) (1979) 4.82
Urinary recovery of N-formimidoyl thienamycin (MK0787) as affected by coadministration of N-formimidoyl thienamycin dehydropeptidase inhibitors. Antimicrob Agents Chemother (1983) 4.25
Phosphonomycin, a new antibiotic produced by strains of streptomyces. Science (1969) 3.89
Pharmacokinetics and tolerance of N-formimidoyl thienamycin (MK0787) in humans. Antimicrob Agents Chemother (1983) 3.46
Antibacterial agents that inhibit lipid A biosynthesis. Science (1996) 3.38
Cephamycins, a new family of beta-lactam antibiotics. IV. In vivo studies. Antimicrob Agents Chemother (1972) 2.88
Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872). Antimicrob Agents Chemother (1997) 2.73
Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis. Antimicrob Agents Chemother (1995) 2.62
In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373. Antimicrob Agents Chemother (1995) 2.37
beta-Lactam antibiotic-induced release of free endotoxin: in vitro comparison of penicillin-binding protein (PBP) 2-specific imipenem and PBP 3-specific ceftazidime. J Infect Dis (1992) 2.27
In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, MK-826 (L-749,345). Antimicrob Agents Chemother (1998) 2.13
Antimicrobial resistance rates among aerobic gram-negative bacilli recovered from patients in intensive care units: evaluation of a national postmarketing surveillance program. Clin Infect Dis (1996) 2.03
Antibacterial activity of imipenem: the first thienamycin antibiotic. Rev Infect Dis (1985) 2.00
Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin. Am J Med (1985) 1.90
Pharmacokinetics of L-749,345, a long-acting carbapenem antibiotic, in primates. Antimicrob Agents Chemother (1997) 1.80
In vitro activities of the potent, broad-spectrum carbapenem MK-0826 (L-749,345) against broad-spectrum beta-lactamase-and extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli clinical isolates. Antimicrob Agents Chemother (1999) 1.57
Phosphonomycin. V. Evaluation in mice. Antimicrob Agents Chemother (Bethesda) (1969) 1.38
Hallucinogenic effects of nutmeg in adolescent. N Y State J Med (1969) 1.34
A stable enzyme-phosphoenolpyruvate intermediate in the synthesis of uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-O-enolpyruvyl ether. Biochemistry (1973) 1.07
The permeability of single capillaries to potassium ions. J Gen Physiol (1978) 1.07
Incidence of multi-resistance in gram-negative aerobes from intensive care units of 10 German hospitals. Scand J Infect Dis Suppl (1991) 0.96
Viral aetiology of enzootic pneumonia in Danish dairy herds: diagnostic tools and epidemiology. Vet Rec (1996) 0.95
Pharmacokinetics in nonhuman primates of a prototype carbapenem active against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (1996) 0.92
Effects of antibiotic therapy on Pseudomonas aeruginosa-induced lung injury in a rat model. Antimicrob Agents Chemother (1999) 0.92
Letter: New antibacterial agent via photofluorination of a bacterial cell wall constituent. Nature (1973) 0.92
Phosphonomycin. 3. Evaluation in vitro. Antimicrob Agents Chemother (Bethesda) (1969) 0.91
Pharmacokinetics of L-671,329 in rhesus monkeys and DBA/2 mice. Antimicrob Agents Chemother (1992) 0.89
Attempts to establish whether glucose is attached to the deoxyribonucleic acid of certain bacteriophages infecting Bacillus subtilis. Biochemistry (1968) 0.86
A new assay for phage hydroxymethylases and its use in Bacillus subtilis transfection. Biochemistry (1968) 0.85
Evaluation of experimental therapeutics in a new mouse model of Helicobacter felis utilizing 16S rRNA polymerase chain reaction for detection. Scand J Gastroenterol (1997) 0.85
A sensitive and specific PCR method to detect Helicobacter felis in a conventional mouse model. Clin Diagn Lab Immunol (1996) 0.84
Muscle blood flow and 86Rb extraction: 86Rb as a capillary flow indicator. Am J Physiol (1968) 0.84
The effects of flow and of hyperosmolal superfusion on the K+ permeability of single capillaries. Microvasc Res (1982) 0.82
Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic. Science (1999) 0.80
Synthesis and analgesic activity of pemedolac (cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]ind ole-1- acetic acid). J Med Chem (1988) 0.80
Oxidative and defluorinative metabolism of fludalanine, 2-2H-3-fluoro-D-alanine. Drug Metab Dispos (1987) 0.80
Chemical modifications of zearalenone. I. J Org Chem (1972) 0.79
The radial protein concentration profile in the interstitial space of the rat ileal mesentery. Microvasc Res (1986) 0.79
Influence of antibiotic class and concentration on the percentage of release of lipopolysaccharide from Escherichia coli. J Infect Dis (1994) 0.78
A modified colloidal osmotic transducer for the determination of transcapillary fluid movement. Microvasc Res (1973) 0.77
Mass-balance approach for estimating transcapillary fluid and protein movement. Am J Physiol (1982) 0.77
Transcapillary protein leakage and fluid movement. Effect of venous pressure. Microvasc Res (1976) 0.77
Antioxidant-based inhibitors of leukotriene biosynthesis. The discovery of 6-[1-[2-(hydroxymethyl)phenyl]-1-propen-3-yl]-2,3-dihydro-5- benzofuranol, a potent topical antiinflammatory agent. J Med Chem (1990) 0.77
Total, non-nutritional, and nutritional blood volume in isolated dog hindlimb. Am J Physiol (1966) 0.77
Non-addictive drug antagonist program in a community setting. Am J Public Health (1973) 0.75
The influence of sympathetic adrenergic nerve stimulation on pre- and postcapillary resistance. Microvasc Res (1973) 0.75
Depression, failure, and guilt. N Y State J Med (1973) 0.75
[Clinical trials with mercapto polycytidylic acid in the treatment of acute childhood leukemia (author's transl)]. Klin Padiatr (1979) 0.75
[Herpesvirus diseases in children with acute leukosis. Treatment with cytosine-arabinoside]. Fortschr Med (1974) 0.75
Iodination of nucleic acids in organic solvents with iodine monochloride. J Biol Chem (1966) 0.75
Single-passage extraction of 86Rb from the circulation of skeletal muscle. Am J Physiol (1969) 0.75
[An ophthalmologic image databank on the Internet]. Ophthalmologe (1998) 0.75
Psychiatric administration. Reason and experience. N Y State J Med (1974) 0.75
[Selection of resistant variants by broad spectrum beta-lactam antibiotics: to what extent is there cross resistance between imipenem and other beta-lactam antibiotics?]. Immun Infekt (1986) 0.75
Community psychiatry: "A bold new approach". Ment Hyg (1969) 0.75
The mass balance method for estimating transcapillary protein transport in an extremity. J Trauma (1985) 0.75
Myocardial blood flow as measured by fractional uptake of rubidium-84 and microspheres. J Nucl Med (1978) 0.75
Antibacterial chemotherapy tests. II. Influence of route and number of treatments on in vivo effectiveness of streptomycin and tetracycline and influence on resistance to rechallenge. Antimicrob Agents Chemother (Bethesda) (1966) 0.75
[A so-called coumarin necrosis in a child]. Monatsschr Kinderheilkd (1973) 0.75
86Rb extraction as an indicator of capillary flow. Circ Res (1971) 0.75
[Prevention of varicella in children on immunosuppressive therapy (author's transl)]. Klin Padiatr (1980) 0.75
[Febrile course of subcutaneous fat necrosis of the newborn with severe generalized manifestations]. Z Kinderheilkd (1968) 0.75
[Interstitial pneumonia in children on cystostatic treatment for malignant systematic disease (author's transl)]. Rontgenblatter (1975) 0.75
In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. J Antibiot (Tokyo) (1995) 0.75
Intensive treatment of the chronic schizophrenic. Psychiatr Q (1967) 0.75
Inhibition of adrenal phenethanolamine-N-methyltransferase by substituted imidazoles. J Med Chem (1972) 0.75
The effect of long-term intraarterial norepinephrine infusion on transcapillary fluid and protein transport. Microvasc Res (1985) 0.75
Conscience and its relation to sex. N Y State J Med (1970) 0.75
Radial diffusion effects in a finite extravascular space surrounding a single capillary. Microvasc Res (1973) 0.75
[Harmonizing of tomography pictures]. Rontgenblatter (1973) 0.75
Microvascular flow distribution and rubidium extraction. Fed Proc (1966) 0.75
Practice of community psychiatry. N Y State J Med (1972) 0.75
Aging--a few biological and chemical considerations. Psychosomatics (1966) 0.75
Comparative effects of norepinephrine, epinephrine, angiotensin on pre- and postcapillary resistance vessels in dog skeletal muscle. Microvasc Res (1975) 0.75
An efficient, stereospecific polyolefinic cyclization. Total synthesis of dl-fichtelite. J Am Chem Soc (1966) 0.75
Quantitative variations in beta-lactam antibiotic released endotoxin from Pseudomonas aeruginosa: in-vivo relevance. Prog Clin Biol Res (1995) 0.75
Psychotherapy and the psychiatric clinic. N Y State J Med (1971) 0.75
[Abdominal neoplasms in childhood]. Med Klin (1973) 0.75
Histamine and protein transport in canine muscle. Microcirc Endothelium Lymphatics (1984) 0.75
[Varicella-zoster-immunoglobulin as a safe prophylaxis of varicella (author's transl)]. Monatsschr Kinderheilkd (1982) 0.75
[Interstitial pneumonia in children with malignancies during cytotoxic therapie. Clinical picture, analysis of promoting factors, and detailed discussion of etiology (author's transl)]. Klin Padiatr (1978) 0.75
[Prevention of cytomegalic inclusion disease in leukemia patients with a cytomegalovirus hyperimmune globulin preparation]. Klin Padiatr (1989) 0.75
Hyperosmolality and transcapillary fluid and protein movement in skeletal muscle. Microvasc Res (1985) 0.75
Inhibition of adrenal phenethanolamine N-methyltransferase by substituted benzimidazoles. J Med Chem (1970) 0.75