| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
[A new semisynthesis of human insulin. Tryptic transpeptidation of porcine insulin with L-threonine tert-butyl ester (author's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1981
|
1.15
|
|
2
|
[Improved preparation of des-alanylB30-insulin (author's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1978
|
1.15
|
|
3
|
Impaired negative cooperativity of the semisynthetic analogues human [LeuB24]- and [LeuB25]-insulins.
|
Biochem Biophys Res Commun
|
1981
|
1.10
|
|
4
|
[Preparation and properties of acetyl derivatives of beef insulin. I].
|
Hoppe Seylers Z Physiol Chem
|
1972
|
0.91
|
|
5
|
Synthesis and characterization of molecular hybrids of insulin and insulin-like growth factor I. The role of the A-chain extension peptide.
|
J Biol Chem
|
1982
|
0.90
|
|
6
|
An insulin with the native sequence but virtually no activity.
|
Biol Chem Hoppe Seyler
|
1994
|
0.88
|
|
7
|
Two mutant forms of human insulin. Structural consequences of the substitution of invariant B24- or B25-phenylalanine by leucine.
|
Hoppe Seylers Z Physiol Chem
|
1981
|
0.88
|
|
8
|
Cross-linking by 1-ethyl-3- (3-dimethylaminopropyl)-carbodiimide (EDC) of a collagen/elastin membrane meant to be used as a dermal substitute: effects on physical, biochemical and biological features in vitro.
|
J Mater Sci Mater Med
|
2001
|
0.87
|
|
9
|
The preparation of two mutant forms of human insulin, containing leucine in position B24 or B25, by enzyme-assisted synthesis.
|
Hoppe Seylers Z Physiol Chem
|
1980
|
0.87
|
|
10
|
Shortened insulin with enhanced in vitro potency.
|
Biol Chem Hoppe Seyler
|
1987
|
0.86
|
|
11
|
Negative and positive site-site interactions, and their modulation by pH, insulin analogs, and monoclonal antibodies, are preserved in the purified insulin receptor.
|
Proc Natl Acad Sci U S A
|
1988
|
0.84
|
|
12
|
Crosslinked insulins: preparation, properties, and application.
|
Adv Exp Med Biol
|
1977
|
0.83
|
|
13
|
[B-chain shortening of matrix-bound insulin by pepsin, I:Preparation and properties of bovine des-pentapeptide(B26-30) insulin (suthor's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1975
|
0.82
|
|
14
|
Reduction of S-sulpho groups by tributylphosphine: an improved method for the recombination of insulin chains.
|
Hoppe Seylers Z Physiol Chem
|
1975
|
0.80
|
|
15
|
The solution structure of a superpotent B-chain-shortened single-replacement insulin analogue.
|
Protein Sci
|
1999
|
0.80
|
|
16
|
Molecular basis of insulin action: contributions of chemical modifications and synthetic approaches.
|
Diabetes
|
1972
|
0.80
|
|
17
|
Structure-function relationships of des-(B26-B30)-insulin.
|
Int J Pept Protein Res
|
1996
|
0.80
|
|
18
|
Cross-linking of insulin induced by iodination.
|
Horm Metab Res
|
1970
|
0.79
|
|
19
|
Presentation of insulin and insulin A chain peptides to mouse T cells: involvement of cysteine residues.
|
Mol Immunol
|
1991
|
0.78
|
|
20
|
Analysis of protein self-association at constant concentration by fluorescence-energy transfer.
|
Eur J Biochem
|
1998
|
0.78
|
|
21
|
The role of the C-terminus of the insulin B-chain in modulating structural and functional properties of the hormone.
|
Int J Pept Protein Res
|
1995
|
0.78
|
|
22
|
Preparation and application of Nalpha-B1,Nepsilon-B29-bis (ter.-butyloxycarbonyl)insulin.
|
Hoppe Seylers Z Physiol Chem
|
1978
|
0.78
|
|
23
|
Preparation and properties of citraconylinsulins.
|
Hoppe Seylers Z Physiol Chem
|
1982
|
0.77
|
|
24
|
Proteolyses of a fluorogenic insulin derivative and native insulin in reversed micelles monitored by fluorescence emission, reversed-phase high-performance liquid chromatography, and capillary zone electrophoresis.
|
Anal Biochem
|
1994
|
0.77
|
|
25
|
Xid-defective male (CBA/N X C57BL/6)F1 accessory cells present bovine insulin to long-term cultured F1-restricted T-cells.
|
Immunogenetics
|
1982
|
0.77
|
|
26
|
Preparation and biological properties of [LeuB24, LeuB25]human insulin.
|
Hoppe Seylers Z Physiol Chem
|
1981
|
0.77
|
|
27
|
Semisynthetic des-(B27-B30)-insulins with modified B26-tyrosine.
|
Biol Chem Hoppe Seyler
|
1991
|
0.77
|
|
28
|
Semisynthetic insulin analogues modified in positions B24, B25 and B29.
|
Biol Chem Hoppe Seyler
|
1994
|
0.76
|
|
29
|
[LeuB24]- and [LeuB25]insulins are not antagonists of lipogenesis in adipocytes.
|
Hoppe Seylers Z Physiol Chem
|
1982
|
0.76
|
|
30
|
Immobilization of the thrombin inhibitor r-hirudin conserving its biological activity.
|
J Mater Sci Mater Med
|
2001
|
0.76
|
|
31
|
Structure and rotational dynamics of fluorescently labeled insulin in aqueous solution and at the amphiphile-water interface of reversed micelles.
|
Biochemistry
|
1995
|
0.76
|
|
32
|
Semisynthetic insulin analogues.
|
Biochem J
|
1971
|
0.75
|
|
33
|
B-chain shortening of matrix-bound insulin with pepsin, II. Preparation and properties of camel des-pentapeptide (B26-30)- and des-PheB1-des-pentapeptide (B26-30)- insulin.
|
Hoppe Seylers Z Physiol Chem
|
1975
|
0.75
|
|
34
|
[Protein semisynthesis with the help of mixed anhydrides and enzymes: chemistry and synthesis of insulins].
|
Naturwissenschaften
|
1981
|
0.75
|
|
35
|
[B17-D-leucine]insulin and [B17-norleucine]insulin: synthesis and biological properties.
|
Hoppe Seylers Z Physiol Chem
|
1983
|
0.75
|
|
36
|
Enzyme-assisted semisynthesis of shortened B26-modified insulins.
|
Biomed Biochim Acta
|
1991
|
0.75
|
|
37
|
Localisation and dynamics of receptor-insulin contacts by NMR studies on the human insulin receptor ectodomain.
|
Biochem Soc Trans
|
1998
|
0.75
|
|
38
|
[Increased yields of insulin by recycling of non-combined insulin chains].
|
Hoppe Seylers Z Physiol Chem
|
1983
|
0.75
|
|
39
|
Preparation of partially protected des-alanineB30-insulin-B-chain-disulphide and its use in semisynthesis.
|
Int J Pept Protein Res
|
1982
|
0.75
|
|
40
|
[An improved method for the combination of modified insulin chains (author's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1981
|
0.75
|
|
41
|
(A1-phenylalanine) insulin: a new synthetic analogue.
|
Hoppe Seylers Z Physiol Chem
|
1980
|
0.75
|
|
42
|
Selective cleavage of one disulfide bond in insulin: preparation and properties of insulin A7-B7-di-S-sulfonate.
|
Hoppe Seylers Z Physiol Chem
|
1973
|
0.75
|
|
43
|
[B22-D-arginine]insulin: synthesis and biological properties.
|
Hoppe Seylers Z Physiol Chem
|
1982
|
0.75
|
|
44
|
[A21-Asparaginimide] insulin. Saponification of insulin hexamethyl ester, I.
|
Hoppe Seylers Z Physiol Chem
|
1977
|
0.75
|
|
45
|
[Reactions of reduced A- and B-chains with insulin].
|
Diabetologia
|
1968
|
0.75
|
|
46
|
[On the partial reduction of insulin].
|
Hoppe Seylers Z Physiol Chem
|
1968
|
0.75
|
|
47
|
[Preparation and properties of mixed disulfides of insulin with glutathione and thioglycollic acid (author's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1973
|
0.75
|
|
48
|
The synthesis of [A 19-3-iodotyrosine] and [A 19-3,5-diiodotyrosine]insulin (porcine).
|
Hoppe Seylers Z Physiol Chem
|
1983
|
0.75
|
|
49
|
Semisynthesis of human proinsulin, I. Preparation of arginyl-A-chain cyclic bis-disulfide.
|
Hoppe Seylers Z Physiol Chem
|
1981
|
0.75
|
|
50
|
Hair sulfur amino acid analysis.
|
EXS
|
1997
|
0.75
|
|
51
|
[Semisynthetic sheep des-A1-glycine insulin (author's transl)].
|
Hoppe Seylers Z Physiol Chem
|
1975
|
0.75
|
|
52
|
Synthesis and properties of [A19-(p-fluorophenylalanine)] insulin.
|
Biol Chem Hoppe Seyler
|
1988
|
0.75
|
|
53
|
Use of Z-amino acid-glyceryl esters in protease catalyzed peptide synthesis.
|
Biomed Biochim Acta
|
1991
|
0.75
|
|
54
|
A convenient esterification of insulin with boron trifluoride/methanol.
|
Hoppe Seylers Z Physiol Chem
|
1975
|
0.75
|
|
55
|
Studies on the total synthesis of an A7,B7-dicarbainsulin. III. Assembly of segments and generation of biological activity.
|
Biol Chem Hoppe Seyler
|
1990
|
0.75
|
|
56
|
(A14-phenylalanine)insulin: a new synthetic analogue.
|
Hoppe Seylers Z Physiol Chem
|
1980
|
0.75
|
|
57
|
[Synthesis of the A-chain of sheep insulin, using only acid-labile protective groups].
|
Z Naturforsch B
|
1969
|
0.75
|