Published in J Clin Invest on May 01, 1981
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Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin. Br J Pharmacol (1982) 2.01
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Contribution of ADP to the amplification of primary platelet aggregation by platelet activating factor (PAF): modulatory role of aspirin. Agents Actions (1986) 0.75
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Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. Prostaglandins (1980) 0.96
The synthesis of prostaglandins by bovine cerebral microvessels. Prostaglandins Med (1980) 0.95
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Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis. N Engl J Med (1998) 4.08
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Metabolism of [14C]arachidonic acid by human platelets. Biochim Biophys Acta (1976) 2.61
Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem (2000) 2.53
Prostaglandin D2 inhibits the aggregation of human platelets. Thromb Res (1974) 2.35
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The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage. Exp Eye Res (2000) 2.10
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The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3':5'-cyclic monophosphate in platelets. Biochem J (1971) 2.04
Formation of prostaglandins during the aggregation of human blood platelets. J Clin Invest (1973) 1.96
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Activation of suppressor T cells in human autologous mixed lymphocyte culture. J Immunol (1979) 1.90
Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry. Exp Eye Res (1998) 1.88
Malondialdehyde formation as an indicator of prostaglandin production by human platelets. J Lab Clin Med (1976) 1.86
Selective release of archidonic acid from the phospholipids of human platelets in response to thrombin. J Clin Invest (1977) 1.84
Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens. J Biol Chem (1997) 1.84
Reevaluation of ampicillin therapy for Hemophilus influenzae meningitis. An appraisal based on a review of cases of persistent or recurrent infection. Am J Dis Child (1971) 1.82
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. Clin Cancer Res (1999) 1.82
Formation of an intermediate in prostaglandin biosynthesis and its association with the platelet release reaction. J Clin Invest (1974) 1.76
Safety of femoral closure devices after percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet blockade. Am J Cardiol (2000) 1.69
Arachidonic acid-induced human platelet aggregation and prostaglandin formation. Prostaglandins (1973) 1.69
The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia. J Leukoc Biol (1998) 1.67
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The carbon dioxide rate of rise in awake apneic humans. J Clin Anesth (1988) 1.65
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Prostacyclin: a potentially valuable agent for preserving myocardial tissue in acute myocardial ischemia. Science (1978) 1.62
Formation and release of prostaglandins by platelets in response to thrombin. Br J Pharmacol (1970) 1.59
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Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. Circulation (1980) 1.56
Age-related changes in human lens crystallins identified by HPLC and mass spectrometry. Exp Eye Res (1998) 1.53
Post-translational modifications of water-soluble human lens crystallins from young adults. J Biol Chem (1994) 1.53
Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. Proc Natl Acad Sci U S A (1980) 1.52
Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60. Proc Natl Acad Sci U S A (1986) 1.51
Purification of membrane attachment and inhibitory subunits of the proton translocating adenosine triphosphatase from Escherichia coli. Biochemistry (1977) 1.49
Studies on the protective effect of prostacyclin in acute myocardial ischemia. Eur J Pharmacol (1979) 1.47
Synthesis and biological properties of pinane-thromboxane A2, a selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation. Proc Natl Acad Sci U S A (1979) 1.47
Selective binding site for [3H]prostacyclin on platelets. J Clin Invest (1979) 1.47
Identification of possible regions of chaperone activity in lens alpha-crystallin. Exp Eye Res (1996) 1.46
Influence of a randomized clinical trial on practice by participating investigators: lessons from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT). CAVEAT I and II Investigators. J Am Coll Cardiol (1998) 1.42
Inhibition of prostacyclin by treatment of endothelium with aspirin. Correlation with platelet adherence. J Clin Invest (1979) 1.39
Duration of inhibition of platelet prostaglandin formation and aggregation by ingested aspirin or indomethacin. Prostaglandins (1973) 1.39
Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol. J Pharmacol Exp Ther (1983) 1.38
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Human blood prostaglandins: formation during clotting. Prostaglandins (1972) 1.35
Formation of lysophosphatidylcholine by human platelets in response to thrombin. Support for the phospholipase A2 pathway for the liberation of arachidonic acid. J Biol Chem (1981) 1.34
Immunologic studies in chronic lymphocytic leukemia: defective stimulation of T-cell proliferation in autologous mixed lymphocyte culture. J Natl Cancer Inst (1977) 1.34
Stimulation of autologous and allogeneic human T cells by B cells occurs through separate B-cell antigen systems. Cell Immunol (1978) 1.33
Deamidation and disulfide bonding in human lens gamma-crystallins. Exp Eye Res (1998) 1.31
Temperature and nucleotide dependence of calcium release by myo-inositol 1,4,5-trisphosphate in cultured vascular smooth muscle cells. J Biol Chem (1985) 1.30
Modifications of the water-insoluble human lens alpha-crystallins. Exp Eye Res (1996) 1.30
Cytogenetics of fetal abortions. Pediatrics (1967) 1.29
Size of human lens beta-crystallin aggregates are distinguished by N-terminal truncation of betaB1. J Biol Chem (1997) 1.25
The role of the lymphatic system and lymphoid cells in the establishment of immunological memory. Aust J Exp Biol Med Sci (1970) 1.24
Inhibition of aggregation and stimulation of cyclic AMP generation in intact human platelets by the diterpene forskolin. Mol Pharmacol (1982) 1.23
Use of a radioimmunoassay to study thrombin-induced release of PGI2 from cultured endothelium. Thromb Res (1979) 1.22
Malignant peripheral nerve sheath tumor (malignant schwannoma) of urinary bladder in von Recklinghausen neurofibromatosis. Urology (1991) 1.20
Viral hepatitis, postnecrotic cirrhosis, and hepatocellular carcinoma. Lancet (1969) 1.20
Anticardiolipin antibodies in patients with rheumatic diseases. Arthritis Rheum (1987) 1.19
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The sequence of human betaB1-crystallin cDNA allows mass spectrometric detection of betaB1 protein missing portions of its N-terminal extension. J Biol Chem (1996) 1.17
Analysis of angiotensin-stimulated sodium transport in cultured smooth muscle cells from rat aorta. J Cell Physiol (1983) 1.15
Activation of atypical protein kinase C zeta by caspase processing and degradation by the ubiquitin-proteasome system. J Biol Chem (2000) 1.15
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Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells. Proc Natl Acad Sci U S A (1984) 1.14
Cathepsin G is a strong platelet agonist released by neutrophils. Biochem J (1988) 1.14
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In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92. Protein Sci (2001) 1.13
Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters. Biochem Biophys Res Commun (1985) 1.13
Platelet hyperaggregability and the nephrotic syndrome. Thromb Res (1979) 1.12
Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina. Prostaglandins Med (1979) 1.11
Leptomeningeal carcinomatosis: a sequela of cholangiocarcinoma. Am Surg (1997) 1.11
Hordeum and Secale mitotic genomes lie apart in a hybrid. J Cell Sci (1981) 1.11
Antibodies which antagonise the effects of prostacyclin. Nature (1978) 1.10
Oligomerization and phase separation in globular protein solutions. Biophys Chem (1998) 1.10
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Characterization of the inhibitory (epsilon) subunit of the proton-translocating adenosine triphosphatase from Escherichia coli. Biochemistry (1980) 1.09