Published in Pharmacol Rev on March 01, 1980
Resorption of implanted bone prepared from normal and warfarin-treated rats. J Clin Invest (1984) 0.93
The effect of vitamin D treatment on decreased levels of ATP and energy charge in the thoracic aorta of uraemic rats. Br J Exp Pathol (1989) 0.75
Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. J Clin Invest (1987) 2.41
Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis. J Clin Invest (1979) 2.02
Computerized discharge summaries. Arch Phys Med Rehabil (1979) 1.60
Vitamin-D-dependent rickets type II. Resistance of target organs to 1,25-dihydroxyvitamin D. N Engl J Med (1978) 1.59
In vivo-like drug responses of human tumors growing in three-dimensional gel-supported primary culture. Proc Natl Acad Sci U S A (1987) 1.31
Human transforming growth factor-alpha stimulates bone resorption in vitro. J Clin Invest (1985) 1.28
Cadmium accelerates bone loss in ovariectomized mice and fetal rat limb bones in culture. Proc Natl Acad Sci U S A (1988) 1.22
Evidence for extrarenal production of 1 alpha ,25-dihydroxyvitamin D in man. J Clin Invest (1982) 1.21
Inhibition by steroids of parathyroid hormone-induced Ca45 release from embryonic rat bone in vitro. J Pharmacol Exp Ther (1969) 1.19
Hypercalcemia and increases in serum hormone value during prolonged administration of 1alpha,25-dihydroxyvitamin D. N Engl J Med (1978) 1.16
G alpha12/G alpha13 subunits of heterotrimeric G proteins mediate parathyroid hormone activation of phospholipase D in UMR-106 osteoblastic cells. Endocrinology (2005) 1.12
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines. J Cell Physiol (1984) 1.08
Abnormal regulation of circulating 25-hydroxyvitamin D in the Williams syndrome. N Engl J Med (1982) 1.08
Effects of glucagon on serum calcium in the rat and on bone resorption in tissue culture. Endocrinology (1970) 1.04
The metabolic defect of methionine dependence occurs frequently in human tumor cell lines. Biochem Biophys Res Commun (1983) 1.02
Comparison of fetal rat limb bones and neonatal mouse calvaria: effects of parathyroid hormone and 1,25-dihydroxyvitamin D3. Calcif Tissue Int (1983) 1.01
Evidence for abnormal regulation of circulating 1 alpha, 25-dihydroxyvitamin D in patients with pulmonary tuberculosis and normal calcium metabolism. Calcif Tissue Int (1984) 1.01
Hypercalcemia during long-term treatment with 1,25-dihydroxyvitamin D3 in hypoparathyroidism. N Engl J Med (1979) 0.96
Evidence for abnormal regulation of circulating 1 alpha,25-dihydroxyvitamin D in patients with sarcoidosis and normal calcium metabolism. J Clin Invest (1980) 0.96
A bioassay capable of measuring 1 picogram of 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab (1978) 0.93
Elevated overall rates of transmethylation in cell lines from diverse human tumors. In Vitro (1984) 0.92
Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect. J Natl Cancer Inst (1986) 0.91
Parathyroid hormone and calcitonin modify inositol phospholipid metabolism in fetal rat limb bones. J Bone Miner Res (1986) 0.90
Bioassay of 1,25-dihydroxyvitamin D in human plasma purified by partition, alkaline extraction, and high-pressure chromatography. Anal Biochem (1980) 0.90
Insulin-like growth factor I production is essential for anabolic effects of thyroid hormone in osteoblasts. J Bone Miner Res (2000) 0.88
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Parathyroid hormone-induced resorption in fetal rat limb bones is associated with production of the metalloproteinases collagenase and gelatinase B. J Bone Miner Res (1996) 0.88
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells. Proc Natl Acad Sci U S A (1982) 0.88
Enzymatic isolation of cells from neonatal calvaria using two purified enzymes from Clostridium histolyticum. Exp Cell Res (1983) 0.87
Serum interleukin-6 and bone metabolism in patients with thyroid function disorders. J Clin Endocrinol Metab (1997) 0.87
1 alpha,25-dihydroxyvitamin D3 corrects osteomalacia in hypoparathyroidism and pseudohypoparathyroidism. Acta Endocrinol (Copenh) (1983) 0.86
Isolation of osteoclasts from fetal rat long bones. Calcif Tissue Int (1982) 0.85
Calcium transport in isolated bone cells. III. Effects of parathyroid hormone and cyclic 3',5'-AMP. Endocrinology (1975) 0.85
Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures. Endocrinology (1992) 0.84
Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts. J Bone Miner Res (2000) 0.84
Bone anabolic responses to mechanical load in vitro involve COX-2 and constitutive NOS. Connect Tissue Res (2004) 0.84
Potassium effects on bone: comparison of two model systems. Am J Physiol (1983) 0.84
Cytotoxic activity, tumor accumulation, and tissue distribution of ruthenium-103-labeled bleomycin. J Natl Cancer Inst (1981) 0.84
U-73122, a phospholipase C antagonist, inhibits effects of endothelin-1 and parathyroid hormone on signal transduction in UMR-106 osteoblastic cells. Biochim Biophys Acta (1994) 0.84
Bone resorbing activity of vitamin D metabolites and congeners in vitro: influence of hydroxyl substituents in the A ring. Endocrinology (1975) 0.84
Fluoride substitution of vitamin D analogs at C-26 and C-27: enhancement of activity of 25-hydroxyvitamin D but not of 1,25-dihydroxyvitamin D on bone and intestine in vitro. J Pharmacol Exp Ther (1984) 0.83
Effects of facilitation exercise techniques in stroke rehabilitation. Arch Phys Med Rehabil (1970) 0.82
Diurnal rhythms in Ca transfer into bone, Ca release from bone, and bone resorbing activity in serum of rats. Am J Physiol (1992) 0.82
A monolog on analogs: in vitro effects of vitamin D metabolites and consideration of the mineralization question. Calcif Tissue Int (1981) 0.82
Studies on the mechanism of desensitization of the parathyroid hormone-stimulated calcium signal in UMR-106 cells: reversal of desensitization by alkaline phosphatase but not by protein kinase C downregulation. J Bone Miner Res (1994) 0.82
MicroCT quantification of in vitro bone resorption of neonatal murine calvaria exposed to IL-1 or PTH. J Struct Biol (2004) 0.81
Demonstration that circulating 1 alpha, 25-dihydroxyvitamin D is loosely regulated in normal children. J Clin Invest (1981) 0.81
10-Keto or 25-hydroxy substitution confer equivalent in vitro bone-resorbing activity to vitamin D3. Arch Biochem Biophys (1985) 0.81
Levodopa therapy effects on natural history of Parkinsonism. Arch Neurol (1972) 0.81
Phosphatidylcholine-specific phospholipase C inhibitor, tricyclodecan-9-yl xanthogenate (D609), increases phospholipase D-mediated phosphatidylcholine hydrolysis in UMR-106 osteoblastic osteosarcoma cells. Biochim Biophys Acta (2000) 0.81
Vertebral bone resorption in vitro: effects of parathyroid hormone, calcitonin, 1,25 dihydroxyvitamin D3, epidermal growth factor, prostaglandin E2, and estrogen. Calcif Tissue Int (1987) 0.80
The preparation of [35S]homocysteine thiolactone free of [35S]methionine. J Biochem Biophys Methods (1982) 0.79
Reduced free-methionine in methionine-dependent SV40-transformed human fibroblasts synthesizing apparently normal amounts of methionine. J Cell Physiol (1983) 0.79
Bone resorbing activities of 24-hydroxy stereoisomers of 24-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3. Biochem Biophys Res Commun (1975) 0.79
Bone-resorbing activity of analogues of 25-hydroxycholecalciferol and 1,25-dihydroxycholecalciferol: effects of side chain modification and stereoisomerization on responses of fetal rat bones in vitro. Mol Pharmacol (1976) 0.79
Cyclosporine A and FK506 induce osteoclast apoptosis in mouse bone marrow cell cultures. Bone (2004) 0.79
Interaction between amrinone and parathyroid hormone on bone in culture. Am J Physiol (1982) 0.79
Insulin and thyroid hormones stimulate matrix metabolism in primary cultures of articular chondrocytes from young rabbits independently and in combination. Connect Tissue Res (1994) 0.79
Vitamin D-dependent rickets type II. N Engl J Med (1980) 0.78
Evidence for direct non-genomic effects of triiodothyronine on bone rudiments in rats: stimulation of the inositol phosphate second messenger system. Acta Endocrinol (Copenh) (1991) 0.78
Thyroid hormones increase insulin-like growth factor I content in the medium of rat bone tissue. J Bone Miner Res (1993) 0.78
Divergent effects of protein kinase C (PKC) inhibitors staurosporine and bisindolylmaleimide I (GF109203X) on bone resorption. Biochem Pharmacol (2000) 0.78
Protein kinase C involvement in interleukin-6 production by parathyroid hormone and tumor necrosis factor-alpha in UMR-106 osteoblastic cells. J Bone Miner Res (2000) 0.78
A bone resorbing substance from bovine serum albumin (brA). Calcif Tissue Res (1978) 0.78
Expression and phorbol ester-induced down-regulation of protein kinase C isozymes in osteoblasts. J Bone Miner Res (1996) 0.78
Hormone synthesis and secretion by rat parathyroid glands in tissue culture. J Clin Invest (1970) 0.78
Stimulation of interleukin-6 promoter by parathyroid hormone, tumor necrosis factor alpha, and interleukin-1beta in UMR-106 osteoblastic cells is inhibited by protein kinase C antagonists. J Bone Miner Res (2001) 0.78
Involvement of PKC-beta in PTH, TNF-alpha, and IL-1 beta effects on IL-6 promoter in osteoblastic cells and on PTH-stimulated bone resorption. Exp Cell Res (2001) 0.78
Levodopa and physical therapy in treatment of patients with Parkinson's disease. Arch Phys Med Rehabil (1970) 0.78
Alendronate/interleukin-1beta cotreatment increases interleukin-6 in bone and UMR-106 cells: dose dependence and relationship to the antiresorptive effect of alendronate. J Bone Miner Res (1998) 0.77
Serum insulin-like growth factor-I, insulin-like growth factor binding proteins, and bone mineral content in hyperthyroidism. Thyroid (2000) 0.77
Cyclosporine A inhibits bone resorption in cultured neonatal mouse calvaria. J Pharmacol Exp Ther (1987) 0.77
Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells. Cell Signal (2010) 0.77
1 alpha, 25-Dihydroxyvitamin D3 nuclear receptors in pituitary. Science (1980) 0.77
Inhibition of parathyroid hormone and interleukin 1-stimulated bone resorption by cyclosporine A but not by cyclosporine H or F. Transplant Proc (1988) 0.77
Responses of fetal rat bone cells and bone organ cultures to the ionophore, A23187. Calcif Tissue Res (1976) 0.77
Bone resorptive activity of side-chain fluoro derivatives of 25-hydroxy- and 1 alpha,25-dihydroxyvitamin D3 in culture. Mol Pharmacol (1981) 0.77
Inhibition of the hypercalcemic action of vitamin D 3 with imidazole. Endocrinology (1971) 0.77
Dissociation of specific binding of 25-OH-D3 and resorption in fetal rat bones. Mol Cell Endocrinol (1978) 0.77
Effects of the antiestrogens tamoxifen and clomiphene on bone resorption in vitro. Endocrinology (1986) 0.77
In vitro mechanical and cellular responses of neonatal mouse bones to loading using a novel micromechanical-testing device. Calcif Tissue Int (2002) 0.77
Cyclosporines: correlation of immunosuppressive activity and inhibition of bone resorption. Calcif Tissue Int (1989) 0.76
Gallium nitrate inhibits bone resorption and collagen synthesis in neonatal mouse calvariae. J Bone Miner Res (1991) 0.76
Mutual up-regulation of thyroid hormone and parathyroid hormone receptors in rat osteoblastic osteosarcoma 17/2.8 cells. Endocrinology (2001) 0.76
Carbon dioxide and the effect of parathyroid hormone on bone in vitro. Am J Physiol (1974) 0.76
Dose-dependent differential effects of risedronate on gene expression in osteoblasts. Biochem Pharmacol (2011) 0.76
Effects of cyclosporins and transforming growth factor beta 1 on thyroid hormone action in cultured fetal rat limb bones. Calcif Tissue Int (1992) 0.76
Endothelin-1 modulates calcium signaling by epidermal growth factor, alpha-thrombin, and prostaglandin E1 in UMR-106 osteoblastic cells. J Bone Miner Res (1993) 0.76
Characterization of specific thyroid hormone receptors in bone. J Bone Miner Res (1988) 0.76
Tight regulation of circulating 1 alpha,25-dihydroxyvitamin D in black children. N Engl J Med (1985) 0.76
Circadian rhythm of in vitro bone-resorbing activity in human serum. J Clin Endocrinol Metab (1995) 0.75
Triiodothyronine potentiates the stimulatory effects of interleukin-1 beta on bone resorption and medium interleukin-6 content in fetal rat limb bone cultures. J Bone Miner Res (1995) 0.75
Cardiotonic agent milrinone stimulates resorption in rodent bone organ culture. J Clin Invest (1987) 0.75
Ionophores. Chemistry, physiology and potential applications to bone biology. Clin Orthop Relat Res (1977) 0.75
Biological activity of 1,25-dihydroxyvitamin D2 and 24-epi-1,25-dihydroxyvitamin D2. Am J Physiol (1988) 0.75
Ametantrone inhibits prostaglandin--mediated resorption in bone organ culture. Prostaglandins (1984) 0.75
Interaction of cyclosporine A and calcitonin on bone resorption in vitro. Horm Metab Res (1989) 0.75
Role of calcium in the initiation of hormonal effects on bone. Prog Clin Biol Res (1984) 0.75
Effects of changes in serum calcium on hypocalcemic response to thyrocalcitonin in the rat. Am J Physiol (1970) 0.75