F A de la Iglesia

Author PubWeight™ 38.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High throughput genotyping for the detection of a single nucleotide polymorphism in NAD(P)H quinone oxidoreductase (DT diaphorase) using TaqMan probes. Mol Pathol 1999 1.35
2 Juvenile canine drug-induced arthropathy: clinicopathological studies on articular lesions caused by oxolinic and pipemidic acids. Toxicol Appl Pharmacol 1979 1.02
3 In vitro photogenotoxic activity of clinafloxacin: a paradigm predicting photocarcinogenicity. Toxicol Appl Pharmacol 1999 0.97
4 Pancreatic acinar cell neoplasia in male Wistar rats following 2 years of gabapentin exposure. Toxicology 1995 0.95
5 Carcinogenesis bioassay of prazepam (Verstran) in rats and mice. Toxicol Appl Pharmacol 1981 0.94
6 Quantitative microscopy comparison of peroxisome proliferation by the lipid-regulating agent gemfibrozil in several species. Hepatology 1984 0.94
7 Pharmacogenetic application in drug development and clinical trials. Drug Metab Dispos 2001 0.89
8 Carcinogen bioassay and mutagenicity studies with the hypolipidemic agent gemfibrozil. J Natl Cancer Inst 1981 0.89
9 Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone. Toxicol Sci 2002 0.89
10 Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin. Mutat Res 1995 0.88
11 Morphologic features and incidence of spontaneous hyperplastic and neoplastic mammary gland lesions in Wistar rats. Toxicol Pathol 1984 0.87
12 Thiazolidinedione toxicity to isolated hepatocytes revealed by coherent multiprobe fluorescence microscopy and correlated with multiparameter flow cytometry of peripheral leukocytes. Arch Toxicol 2001 0.85
13 High-throughput genotyping method for glutathione S-transferase T1 and M1 gene deletions using TaqMan probes. Res Commun Mol Pathol Pharmacol 1999 0.84
14 alpha2u-Globulin nephropathy and ravens: do ravens of a different feather flock together? Environ Health Perspect 1997 0.84
15 Fine structural changes during reparative phase of canine drug-induced arthropathy. Vet Pathol 1985 0.83
16 Troglitazone-induced heart and adipose tissue cell proliferation in mice. Toxicol Pathol 1999 0.82
17 Teratogenesis of calcium valproate in rabbits. Teratology 1986 0.82
18 Spontaneous and thiazolidinedione-induced B6C3F1 mouse hemangiosarcomas exhibit low ras oncogene mutation frequencies. Toxicol Appl Pharmacol 1999 0.81
19 Teratology studies of ametantrone acetate in rats and rabbits. Teratology 1986 0.80
20 Systemic proliferative changes and clinical signs in cynomolgus monkeys administered a recombinant derivative of human epidermal growth factor. Toxicol Pathol 2001 0.80
21 Histiocytic sarcoma in Wistar rats. A light microscopic, immunohistochemical, and ultrastructural study. Arch Pathol Lab Med 1984 0.80
22 p53 is not inactivated in B6C3F1 mouse vascular tumors arising spontaneously or associated with long-term administration of the thiazolidinedione troglitazone. Toxicol Appl Pharmacol 1999 0.80
23 Absence of in vitro genotoxicity of pyrvinium pamoate in sister-chromatid exchange, chromosome aberration, and HGPRT-locus mutation bioassays. J Toxicol Environ Health 1982 0.80
24 Cynomolgus monkeys (Macaca fascicularis) in preclinical immune function safety testing: development of a delayed-type hypersensitivity procedure. Toxicology 1995 0.79
25 Acridine-induced subcellular and functional changes in isolated human hepatocytes in vitro. J Appl Toxicol 1999 0.79
26 Teratogenesis of calcium valproate in rats. Fundam Appl Toxicol 1983 0.79
27 The effect of phenobarbital and carbon tetrachloride on fatty acid content and composition of phospholipids from the endoplasmic reticulum of rat liver. Toxicol Appl Pharmacol 1978 0.79
28 Immunotoxicologic studies with CI-959, a novel benzothiophene cell activation inhibitor. Toxicology 1995 0.79
29 Experimental studies on reproduction with the lipid-regulating agent gemfibrozil. Fundam Appl Toxicol 1987 0.79
30 Peroxisome induction potential and lipid-regulating activity in rats. Quantitative microscopy and chemical structure-activity relationships. Am J Pathol 1991 0.79
31 Genotyping for Functionally Important Human CYP2D6*4 (B) Mutation Using TaqMan Probes. Methods Mol Med 2001 0.79
32 The pathogenesis of trimethyltin chloride-induced nephrotoxicity. Fundam Appl Toxicol 1987 0.79
33 Perspective on the carcinogenic potential of phenytoin based on rodent tumor bioassays and human epidemiological data. Hum Exp Toxicol 1996 0.78
34 Quantitative assessment of trimethyltin induced pathology of the hippocampus. Toxicol Pathol 1987 0.78
35 Quantitative microscopic evaluation of the endoplasmic reticulum in developing human liver. Am J Pathol 1976 0.78
36 Randomization of animals by computer program for toxicity studies. J Environ Pathol Toxicol Oncol 1987 0.77
37 Regression of pathologic changes induced by the long-term administration of contraceptive steroids to rodents. Toxicol Pathol 1985 0.77
38 Monitoring simultaneous subcellular events in vitro by means of coherent multiprobe fluorescence. Nat Med 1999 0.77
39 Calcium valproate-induced uterine adenocarcinomas in Wistar rats. Toxicology 1992 0.77
40 Cellular hyperplasia in rats following continuous intravenous infusion of recombinant human epidermal growth factor. Vet Pathol 1996 0.76
41 Flow cytometric characterization of lymphocyte subpopulations in the cynomolgus monkey (Macaca fascicularis). Vet Immunol Immunopathol 1993 0.76
42 Elucidation of mitochondrial effects by tetrahydroaminoacridine (tacrine) in rat, dog, monkey and human hepatic parenchymal cells. Arch Toxicol 1998 0.76
43 Lack of hepatotoxic interaction between the anticonvulsant drugs phenytoin, sodium valproate and phenobarbital in the rat. Biochem Pharmacol 1986 0.76
44 Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver. Toxicol Pathol 1997 0.76
45 Philosophy of blind slide reading in toxicologic pathology. Toxicol Pathol 1985 0.75
46 Structure-activity relationships in the induction of mammary gland neoplasia in male rats with substituted aminopyrazoles. Am J Pathol 1986 0.75
47 Morphological and biochemical changes in the liver of various species in experimental phospholipidosis after diethylaminoethoxyhexestrol treatment. Toxicol Appl Pharmacol 1975 0.75
48 Fatty acid content and composition of phospholipids bound to the hepatic endoplasmic reticulum of the rat: effect of pregnancy. Toxicol Appl Pharmacol 1979 0.75
49 Relationship of atrial catecholamines to cytochemistry and fine structure of atrial specific granules. Recent Adv Stud Cardiac Struct Metab 1972 0.75
50 The effect of phenobarbital and carbon tetrachloride on fatty acid content and composition of phospholipids from rat liver. Toxicol Appl Pharmacol 1978 0.75
51 Parkinson-like syndrome in nonhuman primates receiving a tetrahydropyridine derivative. Neurotoxicology 1986 0.75
52 Preclinical toxicology studies with a new antiarrhythmic agent: pirmenol hydrochloride (CI-845). Toxicol Appl Pharmacol 1980 0.75
53 Effects of progesterone metabolites on fatty acids of the hepatic endoplasmic reticulum membranes. Toxicology 1979 0.75
54 Evaluation of chronic toxicity and carcinogenesis in rodents with the synthetic analgesic, tilidine fumarate. Toxicology 1986 0.75
55 Carcinogenesis testing updated. Toxicol Pathol 1984 0.75
56 Acute alterations of tissue Ca++ and lethal tubular cell injury during HgCl2 nephrotoxicity in the rat. Toxicol Pathol 1989 0.75
57 Studies on reproduction in rats with meclofenamate sodium, a nonsteroidal anti-inflammatory agent. Fundam Appl Toxicol 1985 0.75
58 Preclinical toxicology studies with the lipid-regulating agent gemcadiol. Fundam Appl Toxicol 1986 0.75
59 Bacterial and mammalian cell mutagenesis, sister-chromatid exchange, and mouse lung adenoma bioassay with the antineoplastic acridine derivative amsacrine. J Toxicol Environ Health 1984 0.75
60 Phospholipids in the liver of the pregnant rat: changes in fatty acid content and composition. Toxicol Appl Pharmacol 1979 0.75
61 Fatty acid content and composition of phospholipids from the endoplasmic reticulum in developing rat liver. Res Commun Chem Pathol Pharmacol 1981 0.75
62 Functional and subcellular organelle changes in isolated rat and human hepatocytes induced by tetrahydroaminoacridine. Arch Toxicol 1998 0.75
63 Recombinant human epidermal growth factor1-48-induced structural changes in the digestive tract of cynomolgus monkeys (Macaca fascicularis). Toxicol Pathol 1997 0.75
64 Teratology study in rats with amsacrine, an antineoplastic agent. Fundam Appl Toxicol 1986 0.75
65 Changes in phospholipid synthesis of the hepatic endoplasmic reticulum during development. Prog Clin Biol Res 1983 0.75
66 Lack of in vivo and in vitro genotoxicity with the nonsteroid, antiinflammatory agent sodium meclofenamate. Teratog Carcinog Mutagen 1984 0.75
67 Cholecystokinin antagonists--a toxicologic perspective. Drug Metab Rev 1992 0.75
68 Effects of a mammalian cholesterol biosynthesis inhibitor on adipocyte ultrastructure and metamorphosis in Rhodnius prolixus (Hemiptera). Experientia 1980 0.75
69 Teratology study with the synthetic prostaglandin ONO-802 given intravaginally to rabbits. Teratog Carcinog Mutagen 1984 0.75
70 Short-term tests with biochemical end points relevant to the prediction of carcinogenic potential of drugs. Drug Metab Rev 1983 0.75
71 Preclinical toxicology of pirmenol hydrochloride. Angiology 1988 0.75
72 Leukocyte and bone marrow effects of a thiomorpholine quinazosin antihypertensive agent. Toxicol Appl Pharmacol 1985 0.75
73 Preclinical toxicity of the new antineoplastic agent, ametantrone acetate, in mice and dogs. J Appl Toxicol 1986 0.75
74 Carcinogenicity studies in rodents and ripazepam, a minor tranquilizing agent. Fundam Appl Toxicol 1984 0.75
75 Changes by progesterone derivatives in fatty acids from phosphatidylcholine and phosphatidylethanolamine fractions in rat liver endoplasmic reticulum. Exp Toxicol Pathol 1994 0.75
76 Cardiotoxicity study of amsacrine in rats. Toxicol Appl Pharmacol 1985 0.75
77 Preclinical toxicology of pirmenol hydrochloride. Am J Cardiol 1987 0.75
78 Effects of CI-949, a novel antiallergy compound, on host resistance in mice. Fundam Appl Toxicol 1991 0.75
79 Chemical-induced hepatocyte ploidy. Toxicol Appl Pharmacol 1998 0.75
80 Influence of oral contraceptives on the acute effect of amphetamine on the hepatic endoplasmic reticulum of the rat. Toxicology 1977 0.75
81 Phospholipids in the developing rat liver: fatty acid content and composition. Res Commun Chem Pathol Pharmacol 1981 0.75
82 Effects of CI-949, a novel antiallergy agent, on immune function of male Fischer 344 rats. J Pharmacol Exp Ther 1991 0.75
83 Preclinical toxicology studies with the angiotensin-converting enzyme inhibitor quinapril hydrochloride (Accupril). J Toxicol Sci 1996 0.75
84 Functional responses of the rat hepatic endoplasmic reticulum to treatment proposed as a model for cholestasis. Exp Pathol 1983 0.75
85 Two-phase teratology study with the synthetic prostaglandin ONO-802 given intravaginally to rats. Teratog Carcinog Mutagen 1984 0.75
86 Rodent carcinogenesis bioassay with oxisuran, a selective immunosuppressive agent. Toxicology 1983 0.75
87 Cell cycle dependent distribution of proliferating cell nuclear antigen/cyclin and cdc2-kinase in mouse T-lymphoma cells. J Cell Biochem 1993 0.75
88 Ultrastructural myocardial changes following experimental narrowing of the coronary arteries. Recent Adv Stud Cardiac Struct Metab 1972 0.75
89 Toxicology studies with a stable intravenous formulation of nitroglycerin. J Appl Toxicol 1983 0.75