| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Gas chromatographic assessment of the reproducibility of phenazone plasma half-life in young healthy volunteers.
|
Eur J Clin Pharmacol
|
1974
|
1.68
|
|
2
|
The absorption of cimetidine before and during maintenance treatment with cimetidine and the influence of a meal on the absorption of cimetidine--studies in patients with peptic ulcer disease.
|
Br J Clin Pharmacol
|
1979
|
1.59
|
|
3
|
Stereoselective pharmacokinetics of S-salbutamol after administration of the racemate in healthy volunteers.
|
Eur Respir J
|
1999
|
1.45
|
|
4
|
The pharmacokinetics of cimetidine and its sulphoxide metabolite in patients with normal and impaired renal function.
|
Br J Clin Pharmacol
|
1982
|
1.04
|
|
5
|
Cerebrospinal fluid concentrations of propofol during anaesthesia in humans.
|
Br J Anaesth
|
1998
|
1.02
|
|
6
|
Cimetidine, but not oxmetidine, penetrates into the cerebrospinal fluid after a single intravenous dose.
|
Br J Clin Pharmacol
|
1982
|
1.02
|
|
7
|
Gas chromatographic determination of ethosuximide and phensuximide in plasma and urine of man.
|
J Pharm Pharmacol
|
1973
|
1.01
|
|
8
|
Short- and long-term treatment with cimetidine in peptic ulcer disease and the pharmacokinetics of cimetidine.
|
Scand J Gastroenterol Suppl
|
1979
|
0.98
|
|
9
|
Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension.
|
Clin Pharmacol Ther
|
1981
|
0.94
|
|
10
|
An estimation of the annual incidence of poisoning using automated telephone polling.
|
J Toxicol Clin Toxicol
|
1990
|
0.87
|
|
11
|
Effect of cimetidine and oxmetidine on 24-h gastric acid and pepsin in patients.
|
Scand J Gastroenterol
|
1983
|
0.87
|
|
12
|
Coupled-column chromatography on a Chiral-AGP phase for determination of amlodipine enantiomers in human plasma: an HPLC assay with electrochemical detection.
|
J Pharm Biomed Anal
|
1996
|
0.87
|
|
13
|
No detectable concentrations of oxmetidine but measurable concentrations of cimetidine in cerebrospinal fluid (CSF) during multiple dose treatment.
|
Br J Clin Pharmacol
|
1984
|
0.86
|
|
14
|
Pharmacokinetics of cimetidine after single doses and during continuous treatment.
|
Clin Pharmacokinet
|
1981
|
0.86
|
|
15
|
Pharmacokinetics of cimetidine and its sulphoxide metabolite during haemodialysis.
|
Eur J Clin Pharmacol
|
1982
|
0.85
|
|
16
|
Oral absorption of cimetidine and its clearance in patients with renal failure.
|
Eur J Clin Pharmacol
|
1979
|
0.84
|
|
17
|
Sensitive high-performance liquid chromatographic analysis of amlodipine in human plasma with amperometric detection and a single-step solid-phase sample preparation.
|
J Chromatogr B Biomed Appl
|
1995
|
0.83
|
|
18
|
Acetylation of procaine amide in man. A preliminary communication.
|
Eur J Clin Pharmacol
|
1975
|
0.83
|
|
19
|
Diminished absorption of cimetidine caused by antacids.
|
Lancet
|
1979
|
0.81
|
|
20
|
Low-dose aspirin decreases blood alcohol concentrations by delaying gastric emptying.
|
Eur J Clin Pharmacol
|
1997
|
0.81
|
|
21
|
Gaschromatography of clemastine. A study of plasma kinetics and biological effect.
|
Arzneimittelforschung
|
1978
|
0.80
|
|
22
|
Attomole sensitive radioimmunoassay for cyclic GMP.
|
Second Messengers Phosphoproteins
|
1988
|
0.80
|
|
23
|
Tissue levels of glyceryl trinitrate and cGMP after in vivo administration in rat, and the effect of tolerance development.
|
Can J Physiol Pharmacol
|
1991
|
0.78
|
|
24
|
Pharmacokinetics of chloral hydrate poisoning treated with hemodialysis and hemoperfusion.
|
Acta Med Scand
|
1988
|
0.78
|
|
25
|
Bioanalysis of racemic reboxetine and its desethylated metabolite in a therapeutic drug monitoring setting using solid phase extraction and HPLC.
|
Ther Drug Monit
|
2001
|
0.77
|
|
26
|
Solid-phase extraction with end-capped C2 columns for the routine measurement of racemic citalopram and metabolites in plasma by high-performance liquid chromatography.
|
J Chromatogr B Biomed Sci Appl
|
1997
|
0.77
|
|
27
|
Retention and subsequent liberation of glyceryl trinitrate in organ baths influences the relaxation of bovine mesenteric arteries contracted by various agents.
|
Pharmacol Toxicol
|
1987
|
0.77
|
|
28
|
Human pharmacokinetics of L-3,4-dihydroxyphenylalanine studied with microdialysis.
|
Clin Chem
|
1999
|
0.76
|
|
29
|
Tissue distribution of glyceryl trinitrate and the effect on cGMP levels in rat.
|
Pharmacol Toxicol
|
1989
|
0.76
|
|
30
|
Studies on hexachlorophene-induced myelin lesions in the trigeminal root transitional region in developing and adult mice.
|
Acta Neuropathol
|
1978
|
0.76
|
|
31
|
Sensitive assay of methadone in plasma by using capillary gas chromatography with photoionization detection.
|
J Chromatogr
|
1986
|
0.76
|
|
32
|
Acetylation of procaine amide in man studied with a new gas chromatographic method.
|
Br J Clin Pharmacol
|
1974
|
0.75
|
|
33
|
Steady-state kinetics and dosage requirements of cimetidine in renal failure.
|
Clin Pharmacokinet
|
1981
|
0.75
|
|
34
|
The influence of trichloroethylene and related drugs on the vestibular system.
|
Acta Pharmacol Toxicol (Copenh)
|
1979
|
0.75
|
|
35
|
Steady-state pharmacokinetics of a new 4-gram 5-aminosalicylic acid retention enema in patients with ulcerative colitis in remission.
|
Scand J Gastroenterol
|
1991
|
0.75
|
|
36
|
On-line extraction using an alkyl-diol silica precolumn for racemic citalopram and its metabolites in plasma. Results compared with solid-phase extraction methodology.
|
J Chromatogr B Biomed Sci Appl
|
2001
|
0.75
|
|
37
|
Therapeutic plasma concentrations of cimetidine in normal renal function and dosage requirements in renal failure.
|
Ther Drug Monit
|
1980
|
0.75
|
|
38
|
Pharmacokinetics of oxmetidine, a new histamine H2-receptor antagonist, after single oral and intravenous doses.
|
Eur J Clin Pharmacol
|
1983
|
0.75
|
|
39
|
[Cimetidine--mostly positive experiences after 5 years].
|
Lakartidningen
|
1981
|
0.75
|
|
40
|
Repeated pentagastrin-stimulated gastric acid secretory tests carried out in the evaluation of the pharmacodynamics of a new histamine H2-receptor antagonist, SK&F 93479.
|
Scand J Gastroenterol
|
1984
|
0.75
|
|
41
|
Prizidilol, a combined vasodilatory and beta-adrenoceptor blocking drug, in primary hypertension. A long-term efficacy, tolerance and pharmacokinetic study.
|
Eur J Clin Pharmacol
|
1983
|
0.75
|
|
42
|
Intragastric pH rise with effervescent citrate-cimetidine.
|
Lancet
|
1991
|
0.75
|
|
43
|
Simultaneous determination of glyceryl trinitrate and its two dinitrate metabolites in plasma and tissues by capillary gas chromatography.
|
J Chromatogr
|
1990
|
0.75
|
|
44
|
[Arrhythmia prophylaxis with procanamide: inadequate dosage?].
|
Lakartidningen
|
1972
|
0.75
|
|
45
|
Tissue disposition of glyceryl trinitrate, 1,2-glyceryl dinitrate, and 1,3-glyceryl dinitrate in tolerant and nontolerant rats.
|
Drug Metab Dispos
|
1992
|
0.75
|
|
46
|
Variable bioavailability of papaverine.
|
Pharmacol Toxicol
|
1988
|
0.75
|
|
47
|
Exposure of rabbits to methylchloroform. Vestibular disturbances correlated to blood and cerebrospinal fluid levels.
|
Int Arch Occup Environ Health
|
1978
|
0.75
|