Published in Arch Intern Med on April 01, 1982
Loss-of-function mutations in the thyrotropin receptor gene as a major determinant of hyperthyrotropinemia in a consanguineous community. J Clin Endocrinol Metab (2009) 0.95
Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X). J Clin Endocrinol Metab (2009) 0.94
To treat or not to treat: the role of adjuvant radioiodine therapy in thyroid cancer patients. J Oncol (2012) 0.79
A somatic gain-of-function mutation in the thyrotropin receptor gene producing a toxic adenoma in an infant. Thyroid (2009) 0.75
Consecutive mutational events in a TSHR allele of Arab families with resistance to thyroid stimulating hormone. Thyroid (2012) 0.75
Predictive value of serum thyroglobulin in treated patients with differentiated thyroid carcinoma. Indian J Clin Biochem (1999) 0.75
Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci U S A (2000) 2.49
Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone. J Clin Endocrinol Metab (1967) 2.47
Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone. Thyroid (1999) 2.44
Comparison of administration of recombinant human thyrotropin with withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma. N Engl J Med (1997) 2.20
Moderate hypothyroidism in preparation for whole body 131I scintiscans and thyroglobulin testing. Thyroid (1996) 2.05
CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. J Immunol (2000) 1.99
A comparison of recombinant human thyrotropin and thyroid hormone withdrawal for the detection of thyroid remnant or cancer. J Clin Endocrinol Metab (1999) 1.92
Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases. Clin Endocrinol (Oxf) (1976) 1.92
Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta. Proc Natl Acad Sci U S A (1989) 1.85
Torpor in mice is induced by both leptin-dependent and -independent mechanisms. Proc Natl Acad Sci U S A (1999) 1.84
Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J (1999) 1.78
Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor. J Clin Endocrinol Metab (1996) 1.75
Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. J Clin Invest (1991) 1.75
Resistance to thyroid hormone. Rev Endocr Metab Disord (2000) 1.74
Anti-thyroid peroxidase antibody in patients with autoimmune thyroid disease: possible identity with anti-microsomal antibody. J Clin Endocrinol Metab (1985) 1.69
Brief report: resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene. N Engl J Med (1995) 1.68
Study of four new kindreds with inherited thyroxine-binding globulin abnormalities. Possible mutations of a single gene locus. J Clin Invest (1972) 1.64
Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood. N Engl J Med (1975) 1.63
Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice. Endocrinology (1998) 1.60
Rapid localization of mutations in the thyroid hormone receptor-beta gene by denaturing gradient gel electrophoresis in 18 families with thyroid hormone resistance. J Clin Endocrinol Metab (1992) 1.58
Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters. J Clin Endocrinol Metab (2000) 1.54
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus. Mol Cell Biol (2001) 1.54
The morning-report syndrome and medical search. N Engl J Med (1979) 1.53
Coexisting thyroid and parathyroid disease--are they related? Surgery (1983) 1.51
CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population. J Clin Endocrinol Metab (1995) 1.49
Graves' disease in severe combined immunodeficient mice. J Clin Endocrinol Metab (1995) 1.46
Decreased levels of helper T cells: a possible cause of immunodeficiency in pregnancy. N Engl J Med (1982) 1.46
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH. J Clin Endocrinol Metab (1997) 1.44
Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells. Proc Natl Acad Sci U S A (1977) 1.43
Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene. J Clin Endocrinol Metab (1992) 1.40
Immunosuppression of thyroiditis. Endocrinology (1996) 1.39
Parameters of thyroid function in serum of 16 selected vertebrate species: a study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins. Endocrinology (1970) 1.38
Thyroid dysfunction in chronic renal failure. A study of the pituitary-thyroid axis and peripheral turnover kinetics of thyroxine and triiodothyronine. J Clin Invest (1977) 1.36
Congenital goiter and the development of metastatic follicular carcinoma with evidence for a leak of nonhormonal iodide: clinical, pathological, kinetic, and biochemical studies and a review of the literature. J Clin Endocrinol Metab (1981) 1.36
Characterization of a thyroid hormone receptor expressed in human kidney and other tissues. Proc Natl Acad Sci U S A (1988) 1.33
Identical mutations in unrelated families with generalized resistance to thyroid hormone occur in cytosine-guanine-rich areas of the thyroid hormone receptor beta gene. Analysis of 15 families. J Clin Invest (1993) 1.33
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J Clin Invest (2000) 1.31
A specific growth hormone-binding protein in human plasma: initial characterization. J Clin Endocrinol Metab (1986) 1.31
Thyrotropin regulation by thyroid hormone in thyroid hormone receptor beta-deficient mice. Endocrinology (1997) 1.28
Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone. Mol Endocrinol (1990) 1.26
Thyrotropin controls transcription of the thyroglobulin gene. Proc Natl Acad Sci U S A (1984) 1.24
Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers. Am J Physiol (1994) 1.21
Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha. Proc Natl Acad Sci U S A (2001) 1.19
The preparation of carrier-free iodine isotope-substituted cytosine nucleotides. Biochim Biophys Acta (1974) 1.19
Long-term follow-up study of compensated low-dose 131I therapy for Graves' disease. N Engl J Med (1984) 1.18
Familial thyroxine-binding globulin deficiency in a patient with Turner's syndrome (XO). Genetic study of a kindred. N Engl J Med (1968) 1.18
Hybridization of RNA labelled with 125 I to high specific activity. Nat New Biol (1973) 1.18
Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration. J Clin Endocrinol Metab (1987) 1.18
Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3. Endocrinology (1972) 1.18
T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels. JAMA (1970) 1.17
Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung. Blood (1987) 1.16
Characterization of a third human thyroid hormone receptor coexpressed with other thyroid hormone receptors in several tissues. Mol Endocrinol (1988) 1.16
Studies on suppressor cell function in thyroid diseases. J Clin Endocrinol Metab (1979) 1.16
Nomenclature of thyroid hormone receptor beta-gene mutations in resistance to thyroid hormone: consensus statement from the first workshop on thyroid hormone resistance, July 10-11, 1993, Cambridge, United Kingdom. J Clin Endocrinol Metab (1994) 1.15
Decreased suppressor T-lymphocytes in autoimmune thyroid diseases detected by monoclonal antibodies. J Clin Endocrinol Metab (1982) 1.15
Sex-associated differences in presentation and survival in patients with lung cancer. J Clin Oncol (1990) 1.15
Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. Biochem J (1995) 1.14
Serum tests for measurement of thyroid function. Hormones (1971) 1.14
Pseudomalabsorption of levothyroxine. JAMA (1991) 1.12
Effects of "jet lag" on hormonal patterns. IV. Time shifts increase growth hormone release. J Clin Endocrinol Metab (1983) 1.11
Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females. Oncogene (2010) 1.11
Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone. Metabolism (1972) 1.10
Replacement of Leu227 by Pro in thyroxine-binding globulin (TBG) is associated with complete TBG deficiency in three of eight families with this inherited defect. J Clin Endocrinol Metab (1990) 1.10
A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily. Mol Endocrinol (1990) 1.10
Changes in thyroid-stimulating immunoglobulins during antithyroid therapy. J Clin Endocrinol Metab (1979) 1.09
Translation of thyroglobulin 33S messenger RNA as a means of determining thyroglobulin quaternary structure. Proc Natl Acad Sci U S A (1975) 1.09
Triiodothyronine binding to isolated liver cell nuclei. Endocrinology (1975) 1.08
Genetic polymorphism of rhesus thyroxine-binding prealbumin: evidence for tetrameric structure in primates. Proc Natl Acad Sci U S A (1969) 1.08
Retrospective and prospective study of radiation-induced thyroid disease. Am J Med (1983) 1.08
Serum thyroglobulin in the follow-up of patients with treated differentiated thyroid cancer. J Clin Endocrinol Metab (1994) 1.08
Sleep deprivation in the rat: V. Energy use and mediation. Sleep (1989) 1.07
The radioiodination of ribopolymers for use in hybridizational and molecular analyses. J Biol Chem (1974) 1.07
New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone. J Clin Invest (1992) 1.07
Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin. Proc Natl Acad Sci U S A (1974) 1.07
Binding of T3 in rat liver nuclei. Endocrinology (1974) 1.06
Identification of a thyroid microsomal antigen by Western blot and immunoprecipitation. J Clin Endocrinol Metab (1985) 1.06
Triiodothyronine binding to liver nuclear solubilized proteins in vitro. Endocrinology (1975) 1.06
Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity. J Clin Endocrinol Metab (1997) 1.05
Treatment of resistance to thyroid hormone--primum non nocere. J Clin Endocrinol Metab (1999) 1.05
Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. Mol Endocrinol (2001) 1.05
Quantitative analysis of spontaneous variations of plasma prolactin in normal man. Am J Physiol (1981) 1.05
Kinetic analysis of iodine metabolism. J Clin Endocrinol Metab (1966) 1.04
Radioiodine labeling of ribopolymers for special applications in biology. Methods Cell Biol (1975) 1.04
Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations. J Clin Endocrinol Metab (1974) 1.04
Effects of "jet lag" on hormonal patterns. I. Procedures, variations in total plasma proteins, and disruption of adrenocorticotropin-cortisol periodicity. J Clin Endocrinol Metab (1981) 1.03
Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase. J Clin Invest (1987) 1.02
Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland. Endocrinology (2001) 1.02
Diagnostic use of recombinant human thyrotropin in patients with thyroid carcinoma (phase I/II study). J Clin Endocrinol Metab (1994) 1.02
Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves' disease in a Caucasian population. J Clin Endocrinol Metab (1993) 1.01
High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation. Mol Endocrinol (1993) 1.01
Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men. Am J Physiol (1994) 1.01
Coupled oxidative phosphorylation in muscle of thyrotoxic patients. Am J Med (1968) 1.01
Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site. J Clin Invest (1998) 1.00