Published in Am J Physiol on September 01, 1982
Determinants of passive drug entry into the central nervous system. Cell Mol Neurobiol (2000) 1.14
Brain meets body: the blood-brain barrier as an endocrine interface. Endocrinology (2012) 0.98
Drug delivery systems, CNS protection, and the blood brain barrier. Biomed Res Int (2014) 0.95
Perfusion imaging with a freely diffusible hyperpolarized contrast agent. Magn Reson Med (2011) 0.94
The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses. Cerebrospinal Fluid Res (2006) 0.93
From blood-brain barrier to blood-brain interface: new opportunities for CNS drug delivery. Nat Rev Drug Discov (2016) 0.92
Diet and age interactions with regards to cholesterol regulation and brain pathogenesis. Curr Gerontol Geriatr Res (2010) 0.83
Pharmacokinetics of sparfloxacin in the serum and vitreous humor of rabbits: physicochemical properties that regulate penetration of quinolone antimicrobials. Antimicrob Agents Chemother (1998) 0.77
Vitamin A Supplementation Increases the Uptake of Chylomicron Retinyl Esters into the Brain of Neonatal Rats Raised under Vitamin A-Marginal Conditions. J Nutr (2016) 0.75
Gut-brain communications: not the same at all ages. Endocrinology (2010) 0.75
Clarifying the Ghrelin System's Ability to Regulate Feeding Behaviours Despite Enigmatic Spatial Separation of the GHSR and Its Endogenous Ligand. Int J Mol Sci (2017) 0.75
Platelets Contribute to BBB Disruption Induced by HIV and Alcohol. J Alcohol Drug Depend (2015) 0.75
Signaling mechanisms underlying the vascular myogenic response. Physiol Rev (1999) 4.89
Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. Am J Physiol (1971) 3.26
N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev (1989) 2.28
The large apparent work capability of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat. Ann Neurol (1977) 1.77
Calcium measurement in isolated arterioles during myogenic and agonist stimulation. Am J Physiol (1991) 1.75
Transport of metabolic substrates through the blood-brain barrier. J Neurochem (1977) 1.73
Impaired peripheral vasomotion in diabetes. Diabetes Care (1996) 1.67
Amino acid assignment to one of three blood-brain barrier amino acid carriers. Am J Physiol (1976) 1.56
Vascular dementia and dementia of the Alzheimer type. Cognition, ventricular size, and leuko-araiosis. Arch Neurol (1988) 1.54
Lipid solubility and drug penetration of the blood brain barrier. Proc Soc Exp Biol Med (1974) 1.48
Blood-brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection. Science (1972) 1.40
Regulation of ion channels by protein tyrosine phosphorylation. Am J Physiol Heart Circ Physiol (2001) 1.39
The use and promise of nuclear magnetic resonance imaging in epilepsy. Epilepsia (1984) 1.39
Terminal endothelial cells of lymph capillaries as active transport structures involved in the formation of lymph in rat skin. Lymphology (1993) 1.38
Field dependent transverse relaxation rate increase may be a specific measure of tissue iron stores. Magn Reson Med (1993) 1.37
Kinetics of blood-brain barrier transport of pyruvate, lactate and glucose in suckling, weanling and adult rats. J Neurochem (1979) 1.33
Kinetics of blood-brain transport of hexoses. Biochim Biophys Acta (1975) 1.32
Carrier-mediated blood-brain barrier transport of short-chain monocarboxylic organic acids. Am J Physiol (1973) 1.29
Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol (1987) 1.29
Suicide from river bridges. Aust N Z J Psychiatry (1990) 1.27
Integrins and mechanotransduction of the vascular myogenic response. Am J Physiol Heart Circ Physiol (2001) 1.26
Brain extracellular space and the sink action of cerebrospinal fluid. Measurement of rabbit brain extracellular space using sucrose labeled with carbon 14. Arch Neurol (1967) 1.25
Changes during development in transport processes of the blood-brain barrier. Biochim Biophys Acta (1976) 1.18
Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. Brain Res (1970) 1.17
Suicide and related behaviour from river bridges. A clinical perspective. Br J Psychiatry (1989) 1.17
Dose dependent reduction of glucose utilization by pentobarbital in rat brain. Stroke (1978) 1.13
Nicotine from cigarette smoking increases circulating levels of cortisol, growth hormone, and prolactin in male chronic smokers. Psychopharmacology (Berl) (1982) 1.12
Kinetic analysis of blood-brain barrier transport of amino acids. Biochim Biophys Acta (1975) 1.11
Obsessions and compulsions in Gilles de la Tourette's syndrome. Neurology (1986) 1.11
Epilepsy and the blood-brain barrier. Adv Neurol (1986) 1.10
Radioisotope measurement of brain blood turnover time as a clinical index of brain circulation. J Nucl Med (1967) 1.09
Blood-brain barrier restriction of peptides and the low uptake of enkephalins. Endocrinology (1978) 1.08
Effects of mibefradil and nifedipine on arteriolar myogenic responsiveness and intracellular Ca(2+). Br J Pharmacol (2000) 1.08
Distribution of various classes of radiolabeled tracers in plasma, scalp, and brain. J Nucl Med (1972) 1.07
Interference of scalp and skull with external measurements of brain isotope content. 1. Isotope content of scalp and skull. J Nucl Med (1969) 1.07
Histologic and histochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet Pathol (1990) 1.06
The quest for an image of brain: a brief historical and technical review of brain imaging techniques. Neurology (1978) 1.03
Saturation of blood brain barrier transport of amino acids in phenylketonuria. Arch Neurol (1973) 1.02
Independent blood-brain barrier transport systems for nucleic acid precursors. Biochim Biophys Acta (1975) 1.01
Pressure related apoptosis in neuronal cell lines. J Neurosci Res (2000) 1.01
Role of myosin phosphorylation and [Ca2+]i in myogenic reactivity and arteriolar tone. Am J Physiol (1995) 1.00
Hematocrit of the human cranial blood pool. Circ Res (1965) 1.00
Regulation of rat liver phenylalanine hydroxylase. II. Substrate binding and the role of activation in the control of enzymatic activity. J Biol Chem (1994) 1.00
Immunohistochemical analysis of 3-B-(-) and 7-D-4 epitope expression in canine osteoarthritis. Arthritis Rheum (1993) 0.99
Blood-brain barrier: interface between internal medicine and the brain. Ann Intern Med (1986) 0.99
Carrier mediated blood-brain barrier transport of choline and certain choline analogs. J Neurochem (1978) 0.99
Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site. J Biol Chem (1994) 0.98
Dyschondroplasias, including osteochondrosis, in boars between 25 and 169 days of age: histologic changes. Am J Vet Res (1984) 0.97
Stereospecificity of blood-brain barrier permeability to amino acids. Am J Physiol (1973) 0.97
Lipoproteins and diabetic microvascular complications. Curr Pharm Des (2004) 0.97
N-isopropyl-[123I] p-iodoamphetamine: single-pass brain uptake and washout; binding to brain synaptosomes; and localization in dog and monkey brain. J Nucl Med (1980) 0.97
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult. J Neurochem (1980) 0.96
Effect of albumin binding and amino acid competition on tryptophan uptake into brain. J Neurochem (1977) 0.96
Morphologic and biochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin. Toxicol Pathol (1992) 0.96
Body weight reduction in rats by oral treatment with zinc plus cyclo-(His-Pro). Br J Pharmacol (2009) 0.96
Impairment of peripheral blood flow responses in diabetes resembles an enhanced aging effect. Diabetes Care (1997) 0.95
Aphasia in dementia of the Alzheimer type. Neurology (1985) 0.95
Symposium on membrane transport. Transport in the central nervous system. Proc R Soc Med (1967) 0.94
Blood-brain barrier and DNA changes during the evolution of experimental allergic encephalomyelitis. J Neuropathol Exp Neurol (1974) 0.94
Regional kinetic constants for blood-brain barrier pyruvic acid transport in conscious rats by the monocarboxylic acid carrier. J Neurochem (1986) 0.94
Alzheimer's disease and Parkinson's disease: comparison of speech and language alterations. Neurology (1988) 0.93
[H] Tryptamine and 3H-water as diffusible internal standards for measuring brain extraction of radio-labeled substances following carotid injection. Brain Res (1976) 0.93
Ultrastructural changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet Pathol (1992) 0.93
Dyschondroplasias, including osteochondrosis, in boars between 25 and 169 days of age: radiologic changes. Am J Vet Res (1984) 0.93
Brain distribution spaces of mannitol-3H, inulin-14C, and dextran-14C in the rat. Am J Physiol (1971) 0.93
Induction and rejoining of DNA double-strand breaks in Chinese hamster V79-4 cells irradiated with characteristic aluminum K and copper L ultrasoft X rays. Radiat Res (1997) 0.92
Alteration of microtubule polymerization modulates arteriolar vasomotor tone. Am J Physiol (1999) 0.91
Kinetics of regional blood-brain barrier transport and brain phosphorylation of glucose and 2-deoxyglucose the barbiturate-anesthetized rat. J Neurochem (1982) 0.90
The development of centres of ossification of bones forming elbow joints in young swine. J Anat (1990) 0.90
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain. Pediatr Res (1982) 0.90
Kinetic constants for blood-brain barrier amino acid transport in conscious rats. J Neurochem (1985) 0.90
Effects of difloxacin on the metabolism of glycosaminoglycans and collagen in organ cultures of articular cartilage. Fundam Appl Toxicol (1993) 0.89
Loperamide dependence. J Clin Psychiatry (1992) 0.89
Reduced EDHF responses and connexin activity in mesenteric arteries from the insulin-resistant obese Zucker rat. Diabetologia (2008) 0.89
Troglitazone, but not rosiglitazone, inhibits Na/H exchange activity and proliferation of macrovascular endothelial cells. J Diabetes Complications (2001) 0.88
Blood-brain barrier to carbidopa (MK-486) and Ro 4-4602, peripheral dopa decarboxylase inhibitors. J Pharm Pharmacol (1973) 0.88
Greater number of capillary endothelial cell mitochondria in brain than in muscle. Proc Soc Exp Biol Med (1975) 0.88
Normal blood flow response and vasomotion in the diabetic Charcot foot. J Diabetes Complications (1998) 0.88
Experimental osteoarthritis in dogs: a comparison of the Pond-Nuki and medial arthrotomy methods. Osteoarthritis Cartilage (1996) 0.87
Motor neuron survival and neuritic extension from spinal cord explants induced by factors released from denervated muscle. Brain Res (1984) 0.87
The blood-brain barrier. Exp Eye Res (1977) 0.87
Pharmacological evidence for capacitative Ca(2+) entry in cannulated and pressurized skeletal muscle arterioles. Br J Pharmacol (2001) 0.87
Temporal aspects of Ca(2+) and myosin phosphorylation during myogenic and norepinephrine-induced arteriolar constriction. J Vasc Res (2001) 0.87
Dyschondroplasias of growth cartilages (osteochondrosis) in crossbred commercial pigs at one and 15 days of age: radiological, angiomicrographical and histological findings. Vet Rec (1985) 0.87