Published in Clin Chim Acta on October 27, 1982
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Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesis. J Clin Invest (1988) 1.62
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Conjugated bile acids in serum and secretions in response to cholecystokinin/secretin stimulation in children with cystic fibrosis. Gut (1985) 1.18
Intestinal involvement in progressive systemic sclerosis detected by increased unconjugated serum bile acids. Gut (1987) 1.14
Unconjugated secondary bile acids in the serum of patients with colorectal adenomas. Gut (1995) 1.06
Isolation of a rat intestinal Clostridium strain producing 5 alpha- and 5 beta-bile salt 3 alpha-sulfatase activity. Appl Environ Microbiol (1986) 0.95
Micellar solubilisation of cholesterol is essential for absorption in humans. Gut (2006) 0.93
A novel pathway for biosynthesis of cholestanol with 7 alpha-hydroxylated C27-steroids as intermediates, and its importance for the accumulation of cholestanol in cerebrotendinous xanthomatosis. J Clin Invest (1985) 0.93
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Prolonged large bowel transit increases serum deoxycholic acid: a risk factor for octreotide induced gallstones. Gut (1999) 0.91
Bile acid profiles in peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency. J Clin Invest (1990) 0.88
Differential hepatic processing and biliary secretion of head-group and acyl chains of liposomal phosphatidylcholines. Biochem J (1991) 0.82
Effect of antibiotic treatment on fat absorption in mice with cystic fibrosis. Pediatr Res (2012) 0.81
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The Canadian CT Head Rule for patients with minor head injury. Lancet (2001) 7.91
The Canadian C-spine rule for radiography in alert and stable trauma patients. JAMA (2001) 7.48
Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer (1994) 3.38
Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. Am J Clin Nutr (1994) 3.25
Bile acid biosynthesis. Biochemistry (1992) 3.09
Variation in emergency department use of cervical spine radiography for alert, stable trauma patients. CMAJ (1997) 2.79
CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun (2008) 2.76
Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circ Res (2001) 2.43
Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis (2008) 2.01
Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones. Lab Invest (2001) 1.96
Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus. J Rheumatol (1997) 1.90
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase. J Biol Chem (1996) 1.80
Delta 4-3-oxosteroid 5 beta-reductase deficiency causing neonatal liver failure and hemochromatosis. J Pediatr (1994) 1.79
Phytoestrogen content of purified, open- and closed-formula laboratory animal diets. Lab Anim Sci (1999) 1.73
Attention deficit hyperactivity disorder with reading disabilities: preliminary genetic findings on the involvement of the ADRA2A gene. J Child Psychol Psychiatry (2005) 1.67
The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med (2001) 1.65
The effects of catabolic and anabolic steroids on amino acid incorporation by skeletal-muscle ribosomes. Biochem J (1968) 1.57
Association of tumor necrosis factor microsatellite polymorphisms with HLA-DRB1*04-bearing haplotypes in rheumatoid arthritis patients. Arthritis Rheum (1996) 1.56
Byler-like familial cholestasis in an extended kindred. Arch Dis Child (1996) 1.53
Effect of cold ischemic time and HLA matching in kidneys coming from "young" and "old" donors: do not leave for tomorrow what you can do tonight. Transplantation (2001) 1.50
Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis. Ann Rheum Dis (2007) 1.47
Psoriasis is associated with pleiotropic susceptibility loci identified in type II diabetes and Crohn disease. J Med Genet (2007) 1.44
Failure of ursodeoxycholic acid to prevent a cholestatic episode in a patient with benign recurrent intrahepatic cholestasis: a study of bile acid metabolism. Hepatology (1991) 1.43
Biochemical changes in skin and muscle after thermal injury. Br J Exp Pathol (1970) 1.42
Genetic and morphological findings in progressive familial intrahepatic cholestasis (Byler disease [PFIC-1] and Byler syndrome): evidence for heterogeneity. Hepatology (1997) 1.41
General methods for the analysis of metabolic profiles of bile acids and related compounds in feces. J Lipid Res (1983) 1.41
The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford) (2006) 1.36
Dietary estrogens--a probable cause of infertility and liver disease in captive cheetahs. Gastroenterology (1987) 1.36
Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease. Am J Clin Nutr (1984) 1.35
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids. J Clin Invest (1987) 1.32
Variation in ED use of computed tomography for patients with minor head injury. Ann Emerg Med (1997) 1.29
Production and metabolism of lignans by the human faecal flora. J Appl Bacteriol (1985) 1.28
A study of tremor in multiple sclerosis. Brain (2001) 1.26
Serum bile acid analysis. Clin Chim Acta (1983) 1.25
Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat. Gastroenterology (2001) 1.24
Lignan formation in man--microbial involvement and possible roles in relation to cancer. Lancet (1981) 1.22
Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab (1995) 1.21
Diurnal changes in serum unconjugated bile acids in normal man. Gut (1982) 1.19
Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis. Genes Immun (2003) 1.18
A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder. Mol Psychiatry (2000) 1.16
Autosomal dominant (Beukes) premature degenerative osteoarthropathy of the hip joint maps to an 11-cM region on chromosome 4q35. Am J Hum Genet (1999) 1.14
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis. Genes Immun (2010) 1.13
Origin of lignans in mammals and identification of a precursor from plants. Nature (1982) 1.13
A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population. Genes Immun (2011) 1.12
Differential contribution of CDKAL1 variants to psoriasis, Crohn's disease and type II diabetes. Genes Immun (2009) 1.12
The group separation of plasma and urinary steroids by column chromatography on sephadex LH-20. Clin Chim Acta (1973) 1.09
Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians. Arthritis Rheum (2001) 1.09
The phytoestrogen content of rodent diets. Environ Health Perspect (1999) 1.08
High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. Hum Mol Genet (2001) 1.08
Cathepsin D exon 2 polymorphism associated with general intelligence in a healthy older population. Mol Psychiatry (2003) 1.08
Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens. BMC Neurosci (2001) 1.07
Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats. J Endocrinol (2001) 1.07
Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis. Ann Rheum Dis (2005) 1.07
Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis. J Pediatr (1990) 1.06
Soya--a dietary source of the non-steroidal oestrogen equol in man and animals. J Endocrinol (1984) 1.05
A new cause of progressive intrahepatic cholestasis: 3 beta-hydroxy-C27-steroid dehydrogenase/isomerase deficiency. J Pediatr (1994) 1.04
Fine mapping the TAGAP risk locus in rheumatoid arthritis. Genes Immun (2011) 1.04
Influence of serotonin transporter gene polymorphisms on cognitive decline and cognitive abilities in a nondemented elderly population. Mol Psychiatry (2005) 1.04
A proposed nomenclature for bile acids. J Lipid Res (1992) 1.03
Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis. Ann Rheum Dis (2010) 1.02
Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration. Hepatology (1991) 1.02
Evidence for linkage of the HLA-B locus in Behçet's disease, obtained using the transmission disequilibrium test. Arthritis Rheum (2001) 1.01
A study of the disposition of alpha-methyldopa in newborn infants following its administration to the mother for the treatment of hypertension during pregnancy. Br J Clin Pharmacol (1979) 1.01
Lignans in man and in animal species. Nature (1980) 1.01
Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population. Brain (2004) 1.00
The identification of the weak oestrogen equol [7-hydroxy-3-(4'-hydroxyphenyl)chroman] in human urine. Biochem J (1982) 0.99
Bile acid profiles of human serum and skin interstitial fluid and their relationship to pruritus studied by gas chromatography-mass spectrometry. Clin Sci (Lond) (1982) 0.99
Soybeans inhibit mammary tumors in models of breast cancer. Prog Clin Biol Res (1990) 0.99
Serum unconjugated bile acids as a test for intestinal bacterial overgrowth in dogs. Dig Dis Sci (2000) 0.98
Enteroendocrine cells: neglected players in gastrointestinal disorders? Therap Adv Gastroenterol (2008) 0.98
Characterization of a prolactin gene polymorphism and its associations with systemic lupus erythematosus. Arthritis Rheum (2001) 0.98
Ursodeoxycholic acid therapy in cystic fibrosis-associated liver disease: a dose-response study. Hepatology (1992) 0.98
The excretion of lignans in rats -- evidence for an intestinal bacterial source for this new group of compounds. FEBS Lett (1981) 0.98
Evaluation of three different ways of assessing tremor in multiple sclerosis. J Neurol Neurosurg Psychiatry (2000) 0.97
Linkage of rheumatoid arthritis to insulin-dependent diabetes mellitus loci: evidence supporting a hypothesis for the existence of common autoimmune susceptibility loci. Arthritis Rheum (2000) 0.96
Association of the CCR5 gene with juvenile idiopathic arthritis. Genes Immun (2010) 0.95
Bile acid metabolism in early life: studies of amniotic fluid. J Lipid Res (1990) 0.95
Antibodies to SS-A/Ro-52kD and centromere in autoimmune liver disease: a clue to diagnosis and prognosis of primary biliary cirrhosis. Aliment Pharmacol Ther (2007) 0.95
A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype. Ann Rheum Dis (2008) 0.95
Biliary bile acid composition of the human fetus in early gestation. Pediatr Res (1987) 0.94
Inborn errors of bile acid synthesis. Semin Liver Dis (1987) 0.94
Isoprenoid metabolism in Pneumocystis carinii. J Eukaryot Microbiol (1995) 0.94
FcgammaRIIIA-158V and rheumatoid arthritis: a confirmation study. Rheumatology (Oxford) (2003) 0.94
A ribosomal fraction from cat skin. J Physiol (1968) 0.94
Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration. Clin Genet (2007) 0.93
Hostility changes following antidepressant treatment: relationship to stress and negative thinking. J Psychiatr Res (1997) 0.93
Conjugation of lignans in human urine. FEBS Lett (1980) 0.93
Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause (2001) 0.93
Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. Am J Med Genet (2001) 0.93
Lack of influence of non-inherited maternal HLA-DR alleles on susceptibility to rheumatoid arthritis. Ann Rheum Dis (1995) 0.93
High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical and thermospray mass spectrometric detection. J Chromatogr (1987) 0.92
Phyto-oestrogens and breast cancer. Lancet (1997) 0.92
Antibody to a 63 kilodalton insect protein in ankylosing spondylitis. Ann Rheum Dis (1992) 0.92
Comprehensive study of the biliary bile acid composition of patients with cystic fibrosis and associated liver disease before and after UDCA administration. Hepatology (1990) 0.92
Detection of ubiquinone in parasitic and free-living protozoa, including species devoid of mitochondria. Mol Biochem Parasitol (1994) 0.92
Resolution of liver biopsy alterations in three siblings with bile acid treatment of an inborn error of bile acid metabolism (delta 4-3-oxosteroid 5 beta-reductase deficiency). Hepatology (1993) 0.92
Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine-conjugated species in patients with primary biliary cirrhosis. Hepatology (1999) 0.92
Performance characteristics of reversed-phase bonded silica cartridges for serum bile acid extraction. Biomed Chromatogr (1996) 0.92
The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome. Ann Rheum Dis (2007) 0.91
Clinical pharmacokinetics of therapeutic bile acids. Clin Pharmacokinet (1996) 0.91