Published in J Antibiot (Tokyo) on August 01, 1982
Molecular regulation of beta-lactam biosynthesis in filamentous fungi. Microbiol Mol Biol Rev (1998) 3.68
Isopenicillin N synthetase of Penicillium chrysogenum, an enzyme that converts delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N. Antimicrob Agents Chemother (1985) 1.20
Beta-lactam biosynthesis in a gram-negative eubacterium: purification and characterization of isopenicillin N synthase from Flavobacterium sp. strain SC 12.154. J Bacteriol (1989) 0.84
High-level expression of the Streptomyces clavuligerus isopenicillin N synthase gene in Escherichia coli. Appl Environ Microbiol (1992) 0.78
Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution. Nature (1992) 5.06
A study of the work of a medical social worker in a group medical practice. Can Med Assoc J (1967) 3.70
Microbial utilization of crude oil. Appl Microbiol (1972) 3.23
Effect of nitrate on reduction of ferric iron by a bacterium isolated from crude oil. Can J Microbiol (1981) 2.76
A potent new mode of beta-lactamase inhibition revealed by the 1.7 A X-ray crystallographic structure of the TEM-1-BLIP complex. Nat Struct Biol (1996) 2.66
Degradation of polycyclic aromatic hydrocarbons and aromatic heterocycles by a Pseudomonas species. Can J Microbiol (1988) 2.23
Nutritional factors controlling exocellular protease production by Pseudomonas aeruginosa. J Bacteriol (1980) 2.06
Effects of medium composition on cell pigmentation, cytochrome content, and ferric iron reduction in a Pseudomonas sp. isolated from crude oil. Can J Microbiol (1982) 2.03
Reverse sample genome probing, a new technique for identification of bacteria in environmental samples by DNA hybridization, and its application to the identification of sulfate-reducing bacteria in oil field samples. Appl Environ Microbiol (1991) 1.92
Distribution of Hydrogenase Genes in Desulfovibrio spp. and Their Use in Identification of Species from the Oil Field Environment. Appl Environ Microbiol (1990) 1.92
Primary health care for the poor in the United States and Canada. Int J Health Serv (1972) 1.83
Longitudinal changes and prognostic implications of left ventricular diastolic function in first acute myocardial infarction. Am Heart J (1999) 1.69
The work of a group of doctors in Saskatchewan. Milbank Mem Fund Q (1968) 1.68
Microbial degradation of aromatics and saturates in Prudhoe Bay crude oil as determined by glass capillary gas chromatography. Can J Microbiol (1981) 1.68
Medical problems of civil disorders. Organization of a volunteer group of health professionals to provide medical services in a riot. N Engl J Med (1969) 1.63
Strikes by health workers: a look at the concept, ethics, and impacts. Am J Public Health (1979) 1.63
Functional analysis of the gene encoding the clavaminate synthase 2 isoenzyme involved in clavulanic acid biosynthesis in Streptomyces clavuligerus. J Bacteriol (1995) 1.60
Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus. Gene (1988) 1.58
Quantitative reverse sample genome probing of microbial communities and its application to oil field production waters. Appl Environ Microbiol (1993) 1.56
Value of the Doppler index of myocardial performance in the early phase of acute myocardial infarction. J Am Soc Echocardiogr (2000) 1.54
Structural and kinetic characterization of a beta-lactamase-inhibitor protein. Nature (1994) 1.53
Identification of distinct communities of sulfate-reducing bacteria in oil fields by reverse sample genome probing. Appl Environ Microbiol (1992) 1.49
Fungal Metabolism of n-Alkylbenzenes. Appl Environ Microbiol (1986) 1.48
Effect of amendments on the microbial utilization of oil applied to soil. Appl Microbiol (1974) 1.48
Indoxyl-beta-D-glucuronide, a novel chromogenic reagent for the specific detection and enumeration of Escherichia coli in environmental samples. Can J Microbiol (1988) 1.46
Interpersonal violence: patterns in a Danish community. Am J Public Health (1985) 1.42
Nutrition in patients with cystic fibrosis: a European Consensus. J Cyst Fibros (2002) 1.38
Unmet needs as sociomedical indicators. Int J Health Serv (1976) 1.37
Cloning, sequencing and disruption of a gene from Streptomyces clavuligerus involved in clavulanic acid biosynthesis. Gene (1994) 1.36
Investigation of the Streptomyces clavuligerus cephamycin C gene cluster and its regulation by the CcaR protein. J Bacteriol (1998) 1.35
Cocaine binding at sigma receptors. Eur J Pharmacol (1988) 1.35
Isolation and characterization of a beta-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding gene. J Bacteriol (1990) 1.34
Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces. Mol Gen Genet (1988) 1.34
Discovery of an insertion sequence, IS116, from Streptomyces clavuligerus and its relatedness to other transposable elements from actinomycetes. J Gen Microbiol (1990) 1.30
Biodegradability and crude oil composition. Can J Microbiol (1974) 1.30
In situ degradation of oil in a soil of the boreal region of the Northwest Territories. Can J Microbiol (1978) 1.28
Purification and characterization of exocellular proteases produced by a clinical isolate and a laboratory strain of Pseudomonas aeruginosa. Can J Microbiol (1980) 1.27
Environmental gasoline-utilizing isolates and clinical isolates of Pseudomonas aeruginosa are taxonomically indistinguishable by chemotaxonomic and molecular techniques. Microbiology (1996) 1.23
A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus. Mol Microbiol (1998) 1.23
The effect of sodium on the fermentation of glutamic acid by Peptococcus aerogenes. Biochem Biophys Res Commun (1967) 1.22
Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus. Antimicrob Agents Chemother (1999) 1.22
Deacetoxycephalosporin C synthetase and deacetoxycephalosporin C hydroxylase are two separate enzymes in Streptomyces clavuligerus. J Antibiot (Tokyo) (1985) 1.20
Demonstration of a cell-associated, inactive precursor of an exocellular protease produced by Pseudomonas aeruginosa. Can J Microbiol (1980) 1.19
Studies on the ring-cyclization and ring-expansion enzymes of beta-lactam biosynthesis in Cephalosporium acremonium. Can J Microbiol (1983) 1.19
A pure enzyme catalyzing penicillin biosynthesis. Science (1984) 1.16
Expression of dibenzothiophene-degradative genes in two Pseudomonas species. Can J Microbiol (1990) 1.16
Cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to penicillins by cell-free extracts of Streptomyces clavuligerus. J Antibiot (Tokyo) (1982) 1.16
Surface changes in mild steel coupons from the action of corrosion-causing bacteria. Appl Environ Microbiol (1981) 1.15
Comparison of oil composition changes due to biodegradation and physical weathering in different oils. J Chromatogr A (1998) 1.14
Serial changes and prognostic implications of a Doppler-derived index of combined left ventricular systolic and diastolic myocardial performance in acute myocardial infarction. Am J Cardiol (2000) 1.13
Mineralization of [14C]hexadecane and [14C]phenanthrene in crude oil: specificity among bacterial isolates. Can J Microbiol (1990) 1.12
Effect of emulsan on biodegradation of crude oil by pure and mixed bacterial cultures. Appl Environ Microbiol (1989) 1.11
Cell-free synthesis of delta-(L-alpha-aminoadipyl)-L-cysteine, the first intermediate of penicillin and cephalosporin biosynthesis. Biochem Biophys Res Commun (1986) 1.09
Structure-based design of a potent transition state analogue for TEM-1 beta-lactamase. Nat Struct Biol (1996) 1.09
Lignin peroxidase oxidation of aromatic compounds in systems containing organic solvents. Appl Environ Microbiol (1994) 1.08
Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J Clin Invest (1990) 1.08
An enrichment program for minority students. J Med Educ (1975) 1.08
Purification of isopenicillin N synthetase from Streptomyces clavuligerus. Can J Microbiol (1986) 1.07
Plant Response to Carbon Dioxide Enrichment under Field Conditions: A Simulation. Science (1971) 1.07
Characterization of the diversity of sulfate-reducing bacteria in soil and mining waste water environments by nucleic acid hybridization techniques. Can J Microbiol (1994) 1.07
Molecular analysis of a beta-lactam resistance gene encoded within the cephamycin gene cluster of Streptomyces clavuligerus. J Bacteriol (1996) 1.05
Transposon and spontaneous deletion mutants of plasmid-borne genes encoding polycyclic aromatic hydrocarbon degradation by a strain of Pseudomonas fluorescens. Biodegradation (1996) 1.05
Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,). Biochemistry (2000) 1.03
Purification and characterization of glutamic acid dehydrogenase and -ketoglutaric acid reductase from Peptococcus aerogenes. Can J Microbiol (1972) 1.03
Production of Streptomyces clavuligerus isopenicillin N synthase in Escherichia coli using two-cistron expression systems. J Ind Microbiol (1990) 1.03
Crude oil utilization by fungi. Can J Microbiol (1979) 1.01
Microbial degradation of alkyl carbazoles in Norman wells crude oil. Appl Environ Microbiol (1984) 0.99
Cephalosporin formation by cell-free extracts from Streptomyces clavuligerus. J Antibiot (Tokyo) (1982) 0.98
The family doctor. Milbank Mem Fund Q (1972) 0.98
Repression of beta-lactam production in Cephalosporium acremonium by nitrogen sources. J Antibiot (Tokyo) (1984) 0.97
Ammonium repression of cephalosporin production by Streptomyces clavuligerus. Can J Microbiol (1985) 0.97
Early cephamycin biosynthetic genes are expressed from a polycistronic transcript in Streptomyces clavuligerus. J Bacteriol (2000) 0.97
Quinone epoxides. V. The biosynthesis of terreic acid. Can J Biochem (1969) 0.96
[Accidents due to violence in Arhus over the period of a year. I. Review and extent of violence]. Ugeskr Laeger (1983) 0.96
The aminoterminal propeptide of type III procollagen provides new information on prognosis after acute myocardial infarction. Am J Cardiol (1995) 0.96
The Meharry Medical College Center for Health Care Research. J Natl Med Assoc (1973) 0.96
Relationship between serum amino-terminal propeptide of type III procollagen and changes of left ventricular function after acute myocardial infarction. Circulation (2000) 0.94
Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology (1997) 0.94
Purification and partial characterization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus. J Bacteriol (1990) 0.94
Terminal QRS distortion on admission is better than ST-segment measurements in predicting final infarct size and assessing the Potential effect of thrombolytic therapy in anterior wall acute myocardial infarction. Am J Cardiol (1999) 0.93
Health care for the poor: when oh when? Am J Public Health (1972) 0.93
Enzymatic approach to syntheses of unnatural beta-lactams. Science (1984) 0.93
Transcriptional mapping of the genes encoding the early enzymes of the cephamycin biosynthetic pathway of Streptomyces clavuligerus. Gene (1994) 0.93
Partial purification and characterization of isopenicillin N epimerase activity from Streptomyces clavuligerus. Can J Microbiol (1983) 0.92
Biochemical studies on the activity of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus. Biochem J (1992) 0.91