Published in Immunology on September 01, 1981
Electrical charge of the antigen determines intraarticular antigen handling and chronicity of arthritis in mice. J Clin Invest (1984) 1.75
Flare-up of antigen-induced arthritis in mice after challenge with intravenous antigen: studies on the characteristics of and mechanisms involved in the reaction. Clin Exp Immunol (1984) 1.11
Induction of immunological memory in the skin. Role of local T cell retention. Clin Exp Immunol (1983) 0.98
Flare-up of experimental arthritis in mice with murine recombinant IL-1. Clin Exp Immunol (1992) 0.96
Human single-chain variable fragment that specifically targets arthritic cartilage. Arthritis Rheum (2010) 0.88
Antigen-induced arthritis: inflammation and antigen handling after two different doses of intra-articularly injected antigen. Immunology (1982) 0.86
Increased vulnerability of postarthritic cartilage to a second arthritic insult: accelerated MMP activity in a flare up of arthritis. Ann Rheum Dis (1999) 0.84
Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature (1962) 64.93
The production of arthritis in rabbits by an immunological reaction to fibrin. Br J Exp Pathol (1962) 11.93
Production of a chronic arthritis with ovalbumin. Its retention in the rabbit knee joint. Ann Rheum Dis (1971) 3.73
The chronicity of inflammation and its significance in rheumatoid arthritis. Ann Rheum Dis (1968) 3.31
The pathogenesis of chronic inflammation in experimental antigen-induced arthritis. II. Preferential localization of antigen-antibody complexes to collagenous tissues. J Exp Med (1972) 2.74
Experimental arthritis associated with auto-immunization to inflammatory exudates. Ann Rheum Dis (1966) 2.22
The pathogenesis of chronic inflammation in experimental antigen-induced arthritis. I. The role of antigen on the local immune response. Arthritis Rheum (1972) 2.16
Histochemical studies of rheumatic conditions. I. Observations on the fine structures of the matrix of normal bone and cartilage. Ann Rheum Dis (1953) 2.12
Identification of immunoglobulins and complement in rheumatoid articular collagenous tissues. Arthritis Rheum (1976) 1.94
Antigen retention in joint tissues in antigen-induced synovitis. Clin Exp Immunol (1974) 1.61
Disappearance of radioactive serum albumin from joints in rheumatoid arthritis. Acta Rheumatol Scand (1956) 1.60
Immunoglobulin and specific antibody synthesis in a chronic inflammatory focus: antigen-induced synovitis. J Immunol (1969) 1.52
Persistence of antigen in rabbit synovial membrane. Br J Exp Pathol (1971) 1.46
Mechanism of trapping of immune complexes in joint collagenous tissues. Clin Exp Immunol (1975) 1.38
Immune elimination and immune retention: the relationship between antigen retained in the foot and the elicitation of footpad swelling. Immunology (1980) 1.28
Use of chromium chloride as the coupling agent in a modified plaque assay. Cells producing anti-protein antibody. J Immunol (1971) 1.19
The deposition and formation of immune complexes in collagenous tissues. Clin Immunol Immunopathol (1979) 1.11
Persistence of antigen in nonarthritic joints. Ann Rheum Dis (1975) 1.03
Pathogenesis of chronic inflammation in experimental ferritin-induced arthritis. IV. Immuno-electron microscopic techniques in the study of articular collagenous tissues. Arthritis Rheum (1978) 1.01
99mTc-pertechnetate uptake measurement in the rabbit knee-joint. J Rheumatol (1981) 0.96
Localization of antigen-antibody complexes in intraarticular collagenous tissues. Ann N Y Acad Sci (1975) 0.95
Experimental immune arthritis: host factors. J Rheumatol (1975) 0.92
Electron microscopic morphology of immunoglobulin aggregates and their interactions in rheumatoid articular collagenous tissues. Arthritis Rheum (1978) 0.88
Is local antigen persistence responsible for the chronicity of the experimental immune arthritis of the rabbit. Experientia (1976) 0.82
Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum (1995) 26.94
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest (1998) 6.92
Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis Cartilage (2005) 6.77
Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis (1990) 5.49
Development of a disease activity score based on judgment in clinical practice by rheumatologists. J Rheumatol (1993) 4.62
The prognostic value of anti-cyclic citrullinated peptide antibody in patients with recent-onset rheumatoid arthritis. Arthritis Rheum (2000) 4.10
Interrelationship of outcome measures and process variables in early rheumatoid arthritis. A comparison of radiologic damage, physical disability, joint counts, and acute phase reactants. J Rheumatol (1994) 3.50
Remission in a prospective study of patients with rheumatoid arthritis. American Rheumatism Association preliminary remission criteria in relation to the disease activity score. Br J Rheumatol (1996) 3.36
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis. J Immunol (2001) 3.32
Synovial tissue inflammation in early and late osteoarthritis. Ann Rheum Dis (2005) 3.25
Biannual radiographic assessments of hands and feet in a three-year prospective followup of patients with early rheumatoid arthritis. Arthritis Rheum (1992) 3.05
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra. Arthritis Rheum (1996) 2.92
Reactive arthritis associated with Campylobacter jejuni enteritis. Br Med J (1979) 2.46
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity (2002) 2.31
Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis. A prospective follow-up study of 147 patients. Br J Rheumatol (1992) 2.29
Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis. Ann Rheum Dis (1992) 2.26
Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum (1997) 2.21
Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum (2001) 2.11
The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum (2005) 2.07
Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes. J Clin Invest (1986) 2.00
Antigen-induced and zymosan-induced arthritis in mice: studies on in vivo cartilage proteoglycan synthesis and chondrocyte death. Br J Exp Pathol (1981) 1.94
Genetic ablation of interferon-gamma up-regulates interleukin-1beta expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain. Arthritis Rheum (2001) 1.92
Antibodies against distinct nuclear matrix proteins are characteristic for mixed connective tissue disease. Clin Exp Immunol (1983) 1.92
Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist. Arthritis Rheum (2005) 1.91
Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration? Osteoarthritis Cartilage (2011) 1.88
Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis. Arthritis Rheum (1995) 1.86
Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein. J Exp Med (1989) 1.85
Characterization of the SS-B (La) antigen in adenovirus-infected and uninfected HeLa cells. EMBO J (1983) 1.83
Vertebral osteoporosis in rheumatoid arthritis patients: effect of low dose prednisone therapy. Br J Rheumatol (1992) 1.82
Low-dose prednisone induces rapid reversible axial bone loss in patients with rheumatoid arthritis. A randomized, controlled study. Ann Intern Med (1993) 1.80
Cross-reactivity of anti-DNA antibodies with proteoglycans. Clin Exp Immunol (1984) 1.80
Adult onset Still's disease and viral infections. Ann Rheum Dis (1988) 1.79
Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor alpha, and interleukin-6 levels in rheumatoid arthritis. Longitudinal evaluation during methotrexate and azathioprine therapy. Arthritis Rheum (1993) 1.79
Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases. J Rheumatol (1992) 1.79
Treatment of active rheumatoid arthritis with leflunomide: two year follow up of a double blind, placebo controlled trial versus sulfasalazine. Ann Rheum Dis (2001) 1.78
Bone mass in patients with rheumatoid arthritis. Ann Rheum Dis (1992) 1.77
Electrical charge of the antigen determines intraarticular antigen handling and chronicity of arthritis in mice. J Clin Invest (1984) 1.75
Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint. Lab Invest (1994) 1.71
Unresolved issues in the role of cyclooxygenase-2 in normal physiologic processes and disease. Arch Intern Med (2000) 1.68
TGF-beta and osteoarthritis. Osteoarthritis Cartilage (2007) 1.66
Influence of methotrexate and azathioprine on radiologic progression in rheumatoid arthritis. A randomized, double-blind study. Ann Intern Med (1991) 1.64
Quantitation of anti-RNP and anti-Sm antibodies in MCTD and SLE patients by immunoblotting. Clin Exp Immunol (1985) 1.62
Bone mineral density in patients with recent onset rheumatoid arthritis: influence of disease activity and functional capacity. Ann Rheum Dis (1993) 1.61
Influence of prognostic features on the final outcome in rheumatoid arthritis: a review of the literature. Semin Arthritis Rheum (1988) 1.61
Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections. Osteoarthritis Cartilage (2000) 1.59
Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity. Semin Arthritis Rheum (1998) 1.59
Detection and quantification of experimental joint inflammation in mice by measurement of 99mTc-pertechnetate uptake. Agents Actions (1981) 1.57
Disease activity in rheumatoid arthritis: preliminary report of the Consensus Study Group of the European Workshop for Rheumatology Research. Clin Exp Rheumatol (1993) 1.57
Infections during low-dose methotrexate treatment in rheumatoid arthritis. Semin Arthritis Rheum (1995) 1.56
No support for HLA-DQ encoded susceptibility in rheumatoid arthritis. Arthritis Rheum (1999) 1.54
Radiographic progression on radiographs of hands and feet during the first 3 years of rheumatoid arthritis measured according to Sharp's method (van der Heijde modification). J Rheumatol (1995) 1.53
Recurrent or persistent hematuria. Sign of mesangial immune-complex deposition. N Engl J Med (1974) 1.52
Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial. Br J Rheumatol (1996) 1.51
Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis. Ann Rheum Dis (2006) 1.50
IgA serum levels and disease activity in ankylosing spondylitis: a prospective study. Ann Rheum Dis (1985) 1.49
Antigen handling in antigen-induced arthritis in mice: an autoradiographic and immunofluorescence study using whole joint sections. Am J Pathol (1982) 1.48
Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation. Osteoarthritis Cartilage (1998) 1.48
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity. Arthritis Res Ther (2005) 1.47
Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis. Ann Rheum Dis (2007) 1.47
Quantitation of arthritis by 99mTc-uptake measurements in the mouse knee-joint: correlation with histological joint inflammation scores. Agents Actions (1984) 1.45
Effects of murine recombinant interleukin 1 on synovial joints in mice: measurement of patellar cartilage metabolism and joint inflammation. Ann Rheum Dis (1990) 1.44
Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: a randomized, controlled, double-blind, 52 week clinical trial. Br J Rheumatol (1997) 1.44
Scl-86, a marker antigen for diffuse scleroderma. J Clin Invest (1985) 1.43
Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction. Inflamm Res (2002) 1.41
Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee. Arthritis Rheum (1997) 1.41
Familial vs sporadic rheumatoid arthritis (RA). A prospective study in an early RA inception cohort. Rheumatology (Oxford) (2000) 1.41
TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads. Osteoarthritis Cartilage (2009) 1.41
Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis. J Exp Pathol (Oxford) (1990) 1.40
Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases. Q J Med (1986) 1.39
Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation. Ann Rheum Dis (2006) 1.39
Validity and reliability of joint indices. A longitudinal study in patients with recent onset rheumatoid arthritis. Br J Rheumatol (1993) 1.39
Dual role of IL-12 in early and late stages of murine collagen type II arthritis. J Immunol (1997) 1.38
Sensitivity of a Dutch Health Assessment Questionnaire in a trial comparing hydroxychloroquine vs. sulphasalazine. Scand J Rheumatol (1990) 1.37
Development and validation of response criteria in rheumatoid arthritis: steps towards an international consensus on prognostic markers. Br J Rheumatol (1996) 1.37
Methotrexate-related pulmonary complications in rheumatoid arthritis. Ann Rheum Dis (1994) 1.37
Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints. Am J Pathol (1989) 1.36
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation. Osteoarthritis Cartilage (2001) 1.36
Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice. Biochem Biophys Res Commun (2009) 1.36
Effects of treatment with a fully human anti-tumour necrosis factor alpha monoclonal antibody on the local and systemic homeostasis of interleukin 1 and TNFalpha in patients with rheumatoid arthritis. Ann Rheum Dis (2001) 1.35
Targeting of renal cell carcinoma with iodine-131-labeled chimeric monoclonal antibody G250. J Clin Oncol (1997) 1.35
Individual relationship between progression of radiological damage and the acute phase response in early rheumatoid arthritis. Towards development of a decision support system. J Rheumatol (1997) 1.34
Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis. Ann Rheum Dis (1999) 1.33
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. Arthritis Rheum (2004) 1.32
Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. Arthritis Rheum (2000) 1.32
Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis. Arthritis Rheum (1999) 1.32
Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis. J Rheumatol (1992) 1.32