Published in J Cell Biol on July 01, 1980
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science (2009) 3.78
Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway. J Cell Biol (1985) 2.53
Parotid secretory granules: crossroads of secretory pathways and protein storage. J Dent Res (2005) 1.39
The major tyrosine-sulfated protein of the bovine anterior pituitary is a secretory protein present in gonadotrophs, thyrotrophs, mammotrophs, and corticotrophs. J Cell Biol (1985) 1.32
Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin. Biophys J (1997) 1.17
In cow anterior pituitary, growth hormone and prolactin can be packed in separate granules of the same cell. J Cell Biol (1985) 1.07
Sorting and secretion of adrenocorticotropin in a pituitary tumor cell line after perturbation of the level of a secretory granule-specific proteoglycan. J Cell Biol (1984) 1.05
Molecular organization of prolactin granules. III. Intracellular transport of sulfated glycosaminoglycans and glycoproteins of the bovine prolactin granule matrix. J Cell Biol (1980) 0.96
Elucidating the role of disulfide bond on amyloid formation and fibril reversibility of somatostatin-14: relevance to its storage and secretion. J Biol Chem (2014) 0.83
Hormonal regulation of prolactin storage in a clonal strain of rat pituitary tumor cells. Yale J Biol Med (1983) 0.78
Visualization of a hyaluronan network on the surface of silicone-hydrogel materials. Clin Ophthalmol (2016) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem (1957) 173.99
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur J Biochem (1974) 113.22
Intracellular aspects of the process of protein synthesis. Science (1975) 25.21
An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J Cell Biol (1967) 12.04
Stereological principles for morphometry in electron microscopic cytology. Int Rev Cytol (1969) 9.36
High-resolution autoradiogaphy. II. The problem of resolution. J Cell Biol (1962) 6.38
Radioautographic visualization of the incorporation of galactose-3H and mannose-3H by rat thyroids in vitro in relation to the stages of thyroglobulin synthesis. J Cell Biol (1969) 3.12
The visualization of human erythrocyte membrane proteins and glycoproteins in SDS polyacrylamide gels employing a single staining procedure. Anal Biochem (1976) 1.72
Sulfated compounds in the zymogen granules of the guinea pig pancreas. J Cell Biol (1978) 1.20
Solubilization of NADH-cytochrome b5 reductase from liver microsomes by lysosomal digestion. J Biochem (1970) 1.06
Molecular organization of rat prolactin granules. I. In vitro stability of intact and "membraneless" granules. J Cell Biol (1975) 1.04
Distribution and metabolism of glycoproteins and glycosaminoglycans in subcellular fractions of brain. Biochemistry (1975) 1.02
The identification of membrane glycocomponents in polyacrylamide gels: a rapid method using 125I-labeled lectins. Anal Biochem (1977) 1.02
Synaptosomal plasma membrane glycoproteins: fractionation by affinity chromatography on concanavalin A. Brain Res (1975) 1.02
Ionic interactions between bovine chymotrypsinogen A and chondroitin sulfate A.B.C.. A possible model for molecular aggregation in zymogen granules. J Cell Biol (1978) 0.98
Molecular organization of prolactin granules. III. Intracellular transport of sulfated glycosaminoglycans and glycoproteins of the bovine prolactin granule matrix. J Cell Biol (1980) 0.96
Rapid automatic analysis of sugar components of glycoproteins. II. Neutral sugars. Anal Biochem (1969) 0.95
Presence of sulfated proteoglycans in prolactin secretory granules isolated from the rat pituitary gland. Biochim Biophys Acta (1976) 0.94
Sulfated glycopeptides from rat brain glycoproteins. Biochemistry (1970) 0.91
Synthesis and subcellular distribution of heparan sulfate in the rat exocrine pancreas. Arch Biochem Biophys (1977) 0.87
Composition and biogenesis of complex carbohydrates of ox adrenal chromaffin granules. Neuroscience (1977) 0.87
Isolation of prolactin granules from rat anterior pituitary glands. Endocrinology (1973) 0.85
Ultrastructural localization of prolactin, growth hormone and luteinizing hormone by immunocytochemical techniques in the bovine pituitary. Cell Tissue Res (1976) 0.84
Studies on in vitro synthesis and secretion of growth hormone and prolactin. I. Hormone pulse labeling with radioactive leucine. Endocrinology (1972) 0.84
Separation of rat pituitary growth hormone and prolactin by SDS polyacrylamide gel electrophoresis. Endocrinology (1974) 0.83
Molecular and cellular physiology of intracellular calcium stores. Physiol Rev (1994) 5.04
CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci (2001) 4.12
"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells? Proc Natl Acad Sci U S A (1988) 2.99
Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons. Nature (1989) 2.94
Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells. J Cell Biol (1987) 2.57
Activation of a muscarinic receptor selectively inhibits a rapidly inactivated Ca2+ current in rat sympathetic neurons. Proc Natl Acad Sci U S A (1987) 2.54
Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway. J Cell Biol (1985) 2.53
Neurotransmitter release: fusion or 'kiss-and-run'? Trends Cell Biol (1994) 2.47
Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol (1984) 2.33
Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs. J Cell Biol (1978) 2.31
The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment. J Cell Biol (1990) 2.03
Composition of cellular membranes in the pancreas of the guinea pig. I. Isolation of membrane fractions. J Cell Biol (1971) 2.03
Synaptic vesicles: is kissing a matter of competence? Trends Cell Biol (2001) 2.00
Neurocan is upregulated in injured brain and in cytokine-treated astrocytes. J Neurosci (2000) 1.95
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol (2009) 1.89
The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth. J Cell Biol (1994) 1.83
Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells. J Biol Chem (1992) 1.80
Composition of cellular membranes in the pancreas of the guinea pig. II. Lipids. J Cell Biol (1971) 1.75
Overexpression of calreticulin increases the Ca2+ capacity of rapidly exchanging Ca2+ stores and reveals aspects of their lumenal microenvironment and function. J Cell Biol (1995) 1.66
BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+. J Biol Chem (1997) 1.65
Spontaneous [Ca2+]i fluctuations in rat chromaffin cells do not require inositol 1,4,5-trisphosphate elevations but are generated by a caffeine- and ryanodine-sensitive intracellular Ca2+ store. J Biol Chem (1990) 1.63
Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol (1987) 1.63
The cell biology of experimental pancreatitis. N Engl J Med (1987) 1.61
High-resolution calcium mapping of the endoplasmic reticulum-Golgi-exocytic membrane system. Electron energy loss imaging analysis of quick frozen-freeze dried PC12 cells. Mol Biol Cell (1997) 1.59
Endoplasmic reticulum: a dynamic patchwork of specialized subregions. Mol Biol Cell (1992) 1.59
Extracellular calcium and the organization of tight junctions in pancreatic acinar cells. Exp Cell Res (1976) 1.58
Pancreatitis. The role of lysosomes. Dig Dis Sci (1984) 1.56
Intracellular Ca2+ stores in chicken Purkinje neurons: differential distribution of the low affinity-high capacity Ca2+ binding protein, calsequestrin, of Ca2+ ATPase and of the ER lumenal protein, Bip. J Cell Biol (1991) 1.54
The hyaluronic acid binding region as a specific probe for the localization of hyaluronic acid in tissue sections. Application to chick embryo and rat brain. J Histochem Cytochem (1985) 1.52
Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature (1988) 1.52
Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe. J Invest Dermatol (1988) 1.48
Pathways of Ca2+ influx at the plasma membrane: voltage-, receptor-, and second messenger-operated channels. Exp Cell Res (1987) 1.46
Ca2+-dependent and -independent release of neurotransmitters from PC12 cells: a role for protein kinase C activation? J Cell Biol (1984) 1.46
Free cytoplasmic Ca2+ and neurotransmitter release: studies on PC12 cells and synaptosomes exposed to alpha-latrotoxin. Proc Natl Acad Sci U S A (1984) 1.46
Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain. J Biol Chem (1992) 1.45
Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules. J Cell Biol (1994) 1.44
Intracellular Ca2+ pools in PC12 cells. Three intracellular pools are distinguished by their turnover and mechanisms of Ca2+ accumulation, storage, and release. J Biol Chem (1991) 1.42
Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis. Am J Physiol (1982) 1.41
Identification of an O-glycosidic mannose-linked sialylated tetrasaccharide and keratan sulfate oligosaccharides in the chondroitin sulfate proteoglycan of brain. J Biol Chem (1986) 1.40
Freeze-fracture of drug-induced autophagocytosis in the mouse exocrine pancreas. Lab Invest (1980) 1.39
The endoplasmic-sarcoplasmic reticulum of smooth muscle: immunocytochemistry of vas deferens fibers reveals specialized subcompartments differently equipped for the control of Ca2+ homeostasis. J Cell Biol (1993) 1.38
Calcium and pancreatic secretion. I. Subcellular distribution of calcium and magnesium in the exocrine pancreas of the guinea pig. J Cell Biol (1975) 1.35
Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules. J Cell Biol (1993) 1.33
Composition of cellular membranes in the pancreas of the guinea pig. IV. Polyacrylamide gel electrophoresis and amino acid composition of membrane proteins. J Cell Biol (1972) 1.32
Mechanisms of signal transduction at the dopamine D2 receptor. Trends Pharmacol Sci (1989) 1.32
The major tyrosine-sulfated protein of the bovine anterior pituitary is a secretory protein present in gonadotrophs, thyrotrophs, mammotrophs, and corticotrophs. J Cell Biol (1985) 1.32
Tumor promoter phorbol 12-myristate, 13-acetate inhibits phosphoinositide hydrolysis and cytosolic Ca2+ rise induced by the activation of muscarinic receptors in PC12 cells. Biochem Biophys Res Commun (1985) 1.32
In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. Am J Physiol (1985) 1.31
Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R. J Comp Neurol (2000) 1.31
Composition of cellular membranes in the pancreas of the guinea pig. 3. Enzymatic activities. J Cell Biol (1971) 1.31
Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex. J Cell Biol (1980) 1.29
High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. Eur J Biochem (1999) 1.28
Insulin in the cerebrospinal fluid. Nature (1967) 1.28
Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue. J Biol Chem (1994) 1.27
Immunocytochemistry of calciosomes in liver and pancreas. J Cell Biol (1988) 1.27
Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase. Proc Natl Acad Sci U S A (1994) 1.25
Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization. J Clin Invest (1989) 1.23
Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations. J Cell Biol (1980) 1.23
Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. J Cell Sci (1999) 1.23
Novel mannitol-containing oligosaccharides obtained by mild alkaline borohydride treatment of a chondroitin sulfate proteoglycan from brain. J Biol Chem (1979) 1.23
Exocytosis and membrane recycling. Philos Trans R Soc Lond B Biol Sci (1981) 1.23
Pharmacological and functional properties of voltage-independent Ca2+ channels. Cell Calcium (1996) 1.23
Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F. J Biol Chem (1986) 1.23
Calreticulin is a candidate for a calsequestrin-like function in Ca2(+)-storage compartments (calciosomes) of liver and brain. Biochem J (1990) 1.21
EGF raises cytosolic Ca2+ in A431 and Swiss 3T3 cells by a dual mechanism. Redistribution from intracellular stores and stimulated influx. Exp Cell Res (1987) 1.21
The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. J Cell Biol (2000) 1.21
Glycosaminoglycans of brain during development. Biochemistry (1975) 1.20
Acid mucopolysaccharides and proteins of bovine whole brain, white matter and myelin. Biochim Biophys Acta (1967) 1.19
Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain. J Biol Chem (1999) 1.19
Voltage-dependent activation and inactivation of calcium channels in PC12 cells. Correlation with neurotransmitter release. J Biol Chem (1987) 1.19
Control of cytosolic free calcium in rat and chicken osteoclasts. The role of extracellular calcium and calcitonin. J Biol Chem (1989) 1.19
Isolation and characterization of developmentally regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal antibodies. J Biol Chem (1991) 1.18
Muscarinic receptor-induced phosphoinositide hydrolysis at resting cytosolic Ca2+ concentration in PC12 cells. J Cell Biol (1985) 1.18
Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS. J Neurosci (1999) 1.18
Activation of muscarinic receptors in PC12 cells. Stimulation of Ca2+ influx and redistribution. Biochem J (1986) 1.17
Generation of inositol phosphates, cytosolic Ca2+, and ionic fluxes in PC12 cells treated with bradykinin. J Biol Chem (1988) 1.15
Characterization of Slit protein interactions with glypican-1. J Biol Chem (2001) 1.15
Heterogeneity of microsomal Ca2+ stores in chicken Purkinje neurons. EMBO J (1991) 1.14
Vascular endothelial growth factor up-regulation and bronchial wall remodelling in asthma. Clin Exp Allergy (2005) 1.14
Ca2+ homeostasis in the endoplasmic reticulum: coexistence of high and low [Ca2+] subcompartments in intact HeLa cells. J Cell Biol (1997) 1.14
Analysis of photoneutron spectra produced in medical accelerators. Phys Med Biol (2000) 1.13
Studies on alpha-latrotoxin receptors in rat brain synaptosomes: correlation between toxin binding and stimulation of transmitter release. J Neurochem (1982) 1.13
Glypican and biglycan in the nuclei of neurons and glioma cells: presence of functional nuclear localization signals and dynamic changes in glypican during the cell cycle. J Cell Biol (1997) 1.13
TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-zeta/beta, and N-CAM. J Biol Chem (1996) 1.13
Brain contains HNK-1 immunoreactive O-glycans of the sulfoglucuronyl lactosamine series that terminate in 2-linked or 2,6-linked hexose (mannose). J Biol Chem (1997) 1.12
Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican. Biochem Biophys Res Commun (1998) 1.12