PubRank

A Shahinian

Author PubWeight™ 81.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995 16.19
2 Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993 9.84
3 Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 1997 6.15
4 FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998 5.29
5 Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 1997 4.23
6 T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999 4.20
7 ICOS is essential for effective T-helper-cell responses. Nature 2001 4.01
8 Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev 1998 3.92
9 CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity. Blood 1997 2.71
10 Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription. EMBO J 2000 2.48
11 Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 1997 2.46
12 LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J Exp Med 1996 2.14
13 Duration of TCR stimulation determines costimulatory requirement of T cells. Immunity 1996 2.08
14 The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity 1998 2.06
15 Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice. Cell 1996 1.78
16 Costimulation of CD28- T lymphocytes by 4-1BB ligand. J Immunol 1997 1.59
17 TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity 1999 1.56
18 Induction of unresponsiveness and impaired T cell expansion by staphylococcal enterotoxin B in CD28-deficient mice. J Exp Med 1996 1.16
19 Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. J Exp Med 1997 1.15
20 T cell responses are governed by avidity and co-stimulatory thresholds. Eur J Immunol 1996 1.05
21 Skin allograft rejection in CD28-deficient mice. Transplantation 1996 0.99
22 Preclinical evaluation of the penciclovir analog 9-(4-[(18)F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET. J Nucl Med 2001 0.87
23 Induction of autoimmunity in the absence of CD28 costimulation. J Immunol 1996 0.86
24 Evaluation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors. Nucl Med Biol 1999 0.82
25 Alterations in the level of CD45 surface expression affect the outcome of thymic selection. J Immunol 1997 0.80
26 CD28 is not required for rejection of unmanipulated syngeneic and autologous tumors. Eur J Immunol 1997 0.80
27 Acute graft-versus-host disease without costimulation via CD28. Transplantation 1997 0.79
28 CD4 negative mice as a model for immunodeficiency. Philos Trans R Soc Lond B Biol Sci 1993 0.77
29 Alloreactive gamma delta thymocytes utilize distinct costimulatory signals from peripheral T cells. J Immunol 1995 0.76