Published in RNA on July 01, 1995
Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother (2001) 4.17
23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. Proc Natl Acad Sci U S A (2005) 1.24
Effects on translation pausing of alterations in protein and RNA components of the ribosome exit tunnel. J Bacteriol (2008) 1.06
Two new point mutations at A2062 associated with resistance to 16-membered macrolide antibiotics in mutant strains of Mycoplasma hominis. Antimicrob Agents Chemother (2001) 0.91
Impact of ribosomal modification on the binding of the antibiotic telithromycin using a combined grand canonical monte carlo/molecular dynamics simulation approach. PLoS Comput Biol (2013) 0.88
Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target. RNA (1999) 0.81
Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase. RNA (1999) 0.78
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52
Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective. Microbiol Rev (1994) 9.74
Structure of ribosomal RNA. Annu Rev Biochem (1984) 9.44
Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid (1981) 9.00
Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extension. J Mol Biol (1986) 7.87
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie (1987) 4.47
Low-copy-number plasmid-cloning vectors amplifiable by derepression of an inserted foreign promoter. Gene (1984) 4.03
Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli. Nucleic Acids Res (1984) 3.94
Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli. Methods Enzymol (1988) 3.60
Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J Biol Chem (1983) 3.11
Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction. Gene (1982) 2.81
Chloramphenicol-erythromycin resistance mutations in a 23S rRNA gene of Escherichia coli. J Bacteriol (1985) 2.31
Keeping RNA happy. RNA (1995) 2.12
Functional interactions within 23S rRNA involving the peptidyltransferase center. J Bacteriol (1992) 1.74
Identification of a single base change in ribosomal RNA leading to erythromycin resistance. J Biol Chem (1992) 1.54
Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli 23S ribosomal RNA. Nucleic Acids Res (1992) 1.54
Erythromycin binding is reduced in ribosomes with conformational alterations in the 23 S rRNA peptidyl transferase loop. J Mol Biol (1993) 1.53
23S ribosomal ribonucleic acid of macrolide-producing streptomycetes contains methylated adenine. J Bacteriol (1979) 1.52
Point mutations in the 23 S rRNA genes of four lincomycin resistant Nicotiana plumbaginifolia mutants could provide new selectable markers for chloroplast transformation. Mol Gen Genet (1988) 1.46
Methylation of 23S rRNA caused by tlrA (ermSF), a tylosin resistance determinant from Streptomyces fradiae. J Bacteriol (1989) 1.43
The three-dimensional folding of ribosomal RNA; localization of a series of intra-RNA cross-links in 23S RNA induced by treatment of Escherichia coli 50S ribosomal subunits with bis-(2-chloroethyl)-methylamine. Nucleic Acids Res (1991) 1.39
Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase. J Bacteriol (1994) 1.10
23S rRNA domain V, a fragment that can be specifically methylated in vitro by the ErmSF (TlrA) methyltransferase. J Bacteriol (1994) 1.10
Binding sites of the antibiotics pactamycin and celesticetin on ribosomal RNAs. Biochimie (1992) 1.06
Specific structural probing of plasmid-coded ribosomal RNAs from Escherichia coli. Biochimie (1991) 1.02
A repeated decapeptide motif in the C-terminal domain of the ribosomal RNA methyltransferase from the erythromycin producer Saccharopolyspora erythraea. FEBS Lett (1990) 0.81
Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother (2001) 4.17
A "bulged" double helix in a RNA-protein contact site. Proc Natl Acad Sci U S A (1981) 3.16
The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol Microbiol (1999) 2.36
Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. J Bacteriol (2000) 2.25
Interconversion of active and inactive 30 S ribosomal subunits is accompanied by a conformational change in the decoding region of 16 S rRNA. J Mol Biol (1986) 1.97
Basis for prokaryotic specificity of action of aminoglycoside antibiotics. EMBO J (1999) 1.91
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. Mol Microbiol (2000) 1.91
Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse. Diabetologia (2012) 1.83
Isolation of temperature-sensitive mutants of 16 S rRNA in Escherichia coli. J Mol Biol (1989) 1.82
Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study. Antimicrob Agents Chemother (2003) 1.78
Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry. RNA (2000) 1.72
Specificity and stability of the Acromyrmex-Pseudonocardia symbiosis. Mol Ecol (2013) 1.54
The antibiotics micrococcin and thiostrepton interact directly with 23S rRNA nucleotides 1067A and 1095A. Nucleic Acids Res (1994) 1.46
Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction. J Mol Biol (1999) 1.32
Multicentric squamous cell carcinomas of the lower female genital tract. Eleven cases with epidermoid carcinoma of both vulva and cervix. Am J Obstet Gynecol (1967) 1.30
A ribonuclease-resistant region of 5S RNA and its relation to the RNA binding sites of proteins L18 and L25. Nucleic Acids Res (1979) 1.22
Higher order structure in the 3'-minor domain of small subunit ribosomal RNAs from a gram negative bacterium, a gram positive bacterium and a eukaryote. J Mol Biol (1983) 1.22
Antibiotic interactions at the GTPase-associated centre within Escherichia coli 23S rRNA. EMBO J (1989) 1.21
Ribosomal proteins L11 and L10.(L12)4 and the antibiotic thiostrepton interact with overlapping regions of the 23 S rRNA backbone in the ribosomal GTPase centre. J Mol Biol (1993) 1.18
Comparison of Escherichia coli tRNAPhe in the free state, in the ternary complex and in the ribosomal A and P sites by chemical probing. Eur J Biochem (1983) 1.16
Evidence for functional interaction between domains II and V of 23S ribosomal RNA from an erythromycin-resistant mutant. Proc Natl Acad Sci U S A (1985) 1.13
Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase. J Bacteriol (1994) 1.10
Development and testing of improved suicide functions for biological containment of bacteria. Appl Environ Microbiol (1995) 1.06
Binding site of ribosomal proteins on prokaryotic 5S ribonucleic acids: a study with ribonucleases. Biochemistry (1982) 1.05
Secondary structure of prokaryotic 5S ribosomal ribonucleic acids: a study with ribonucleases. Biochemistry (1981) 1.04
The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA. Mol Microbiol (2000) 1.03
Specific structural probing of plasmid-coded ribosomal RNAs from Escherichia coli. Biochimie (1991) 1.02
Pseudoknot in domain II of 23 S rRNA is essential for ribosome function. J Mol Biol (1995) 1.00
Recognition of nucleotide G745 in 23 S ribosomal RNA by the rrmA methyltransferase. J Mol Biol (2001) 0.99
Presence of N-acyl homoserine lactones in soil detected by a whole-cell biosensor and flow cytometry. Microb Ecol (2003) 0.92
Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. J Mol Biol (1996) 0.91
Metamobilomics--expanding our knowledge on the pool of plasmid encoded traits in natural environments using high-throughput sequencing. Clin Microbiol Infect (2012) 0.90
Cooperative assembly of proteins in the ribosomal GTPase centre demonstrated by their interactions with mutant 23S rRNAs. Nucleic Acids Res (1995) 0.87
Improved RNA cleavage by LNAzyme derivatives of DNAzymes. Biochem Soc Trans (2004) 0.86
ErmE methyltransferase recognition elements in RNA substrates. J Mol Biol (1998) 0.86
ErmE methyltransferase recognizes features of the primary and secondary structure in a motif within domain V of 23 S rRNA. J Mol Biol (1999) 0.85
Higher-order structure in the 3'-terminal domain VI of the 23 S ribosomal RNAs from Escherichia coli and Bacillus stearothermophilus. J Mol Biol (1984) 0.85
Transcription analysis of the Streptomyces coelicolor A3(2) rrnA operon. Microbiology (1994) 0.84
Requirement for a conserved, tertiary interaction in the core of 23S ribosomal RNA. Proc Natl Acad Sci U S A (1994) 0.84
Molecular mechanism of growth hormone signalling. Endocr J (1998) 0.83
Genetic labelling and application of the isoproturon-mineralizing Sphingomonas sp. strain SRS2 in soil and rhizosphere. Lett Appl Microbiol (2006) 0.82
Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target. RNA (1999) 0.81
Nickel-induced proliferation of both memory and naive T cells in patch test-negative individuals. Clin Exp Immunol (1999) 0.80
Problem patients with vulvar malignancy. Clin Obstet Gynecol (1967) 0.79
Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase. RNA (1999) 0.78
Nickel-induced activation of T cells in individuals with negative patch test to nickel sulphate. Arch Dermatol Res (1999) 0.78
Dexamethasone-induced parturition in cattle. Br Vet J (1974) 0.78
Identification of differentially expressed genes in chemically induced skin tumors. Mol Carcinog (1997) 0.78
Recognition determinants for proteins and antibiotics within 23S rRNA. Biochem Cell Biol (1996) 0.77
The role of GH receptor tyrosine phosphorylation in Stat5 activation. J Mol Endocrinol (1997) 0.77
Regulation of glucagon receptor expression. Acta Physiol Scand (1996) 0.76
Nurse-conducted smoking cessation with minimal intervention in a lung clinic: a randomized controlled study. Eur Respir J (1996) 0.76
The ribosomal S4-RNA fragment melts cooperatively when complexed with protein S4. FEBS Lett (1979) 0.75
A clinical stain for use in selecting biopsy sites in patients with vulvar disease. Obstet Gynecol (1966) 0.75
Echoencephalography in a large city hospital. Rocky Mt Med J (1966) 0.75
[A-scope ultrasonic technique in detection of pregnancy in sows (author's transl)]. Nord Vet Med (1974) 0.75
Reproductive efficiency and incidence of MMA after controlled farrowing using a prostaglandin analogue, cloprostenol. Nord Vet Med (1979) 0.75
[Incidence of MMA after prostaglangin-induced parturition in swine]. Tierarztl Prax (1977) 0.75
[Fibrous perimetritis in gilts resulting in dystocia. A preliminary report (author's transl)]. Nord Vet Med (1973) 0.75
[Induction of parturition in cows with a corticosteroid (dexamethasone)]. Nord Vet Med (1971) 0.75
Bowel cancer. N Z Med J (1979) 0.75
[Incidence of MMA after prostaglandin-induced parturition (author's transl)]. Nord Vet Med (1976) 0.75
[Porcine pregnancy detection with a newly developed ultrasonic a-scan-device (author's transl)]. Zuchthygiene (1976) 0.75
The accuracy of porcine pregnancy diagnosis by a newly developed ultrasonic A-scan tester. Br Vet J (1976) 0.75