PubRank

C L Cooney

Author PubWeight™ 58.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Thermophilic anaerobic digestion of solid waste for fuel gas production. Biotechnol Bioeng 1975 2.28
2 Enzymatic degradation of glycosaminoglycans. Crit Rev Biochem Mol Biol 1995 2.21
3 Microbial utilization of methanol. Adv Appl Microbiol 1972 2.17
4 Isolation and characterization of a thermotolerant methanol-utilizing yeast. Appl Microbiol 1973 1.95
5 Polysaccharide lyases. Appl Biochem Biotechnol 1986 1.81
6 Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding. J Biol Chem 1999 1.70
7 Purification and characterization of heparinase from Flavobacterium heparinum. J Biol Chem 1985 1.43
8 Growth of Enterobacter aerogenes in a chemostat with double nutrient limitations. Appl Environ Microbiol 1976 1.36
9 Heparinase inhibits neovascularization. Proc Natl Acad Sci U S A 1994 1.19
10 Differential anticoagulant activity of heparin fragments prepared using microbial heparinase. J Biol Chem 1982 1.17
11 Streptococcus mutans dextransucrase: a review. Adv Appl Microbiol 1978 1.16
12 Heparinase production by Flavobacterium heparinum. Appl Environ Microbiol 1981 1.15
13 Cloning and expression of heparinase I gene from Flavobacterium heparinum. Proc Natl Acad Sci U S A 1993 1.14
14 Mode of action of heparin lyase on heparin. Biochim Biophys Acta 1982 1.07
15 Model of oxygen transport limitations in hollow fiber bioreactors. Biotechnol Bioeng 1991 1.01
16 An enzymatic system for removing heparin in extracorporeal therapy. Science 1982 0.99
17 Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation. Proc Natl Acad Sci U S A 1996 0.99
18 Measurement of heat evolution and correlation with oxygen consumption during microbial growth. Biotechnol Bioeng 1969 0.98
19 An immobilized microbial heparinase for blood deheparinization. Appl Biochem Biotechnol 1984 0.97
20 Computer-aided material balancing for prediction of fermentation parameters. Biotechnol Bioeng 1977 0.95
21 Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum. Biochem J 1996 0.94
22 Bioreactors: design and operation. Science 1983 0.94
23 A stereochemical approach to pyranose ring flexibility: its implications for the conformation of dermatan sulfate. Proc Natl Acad Sci U S A 1994 0.93
24 Distribution of dextransucrase in Streptococcus mutans and observations on the effect of soluble dextran on dextransucrase activities. Infect Immun 1977 0.92
25 Production of gramicidin S synthetases by Bacillus brevis in continuous culture. J Gen Microbiol 1976 0.91
26 Transient response of Enterobacter aerogenes under a dual nutrient limitation in a chemostat. Biotechnol Bioeng 1976 0.89
27 Purification of plasmids by triplex affinity interaction. Nucleic Acids Res 1998 0.89
28 Heparinase I from Flavobacterium heparinum. Mapping and characterization of the heparin binding domain. J Biol Chem 1996 0.88
29 Immobilized heparin lyase system for blood deheparinization. Methods Enzymol 1988 0.88
30 Application of dynamic calorimetry for monitoring fermentation processes. Biotechnol Bioeng 1976 0.87
31 Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: problems and bottlenecks. Trends Biotechnol 1999 0.87
32 Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application. Proc Natl Acad Sci U S A 1999 0.86
33 Heparinase I from Flavobacterium heparinum: the role of the cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis. Biochemistry 1995 0.84
34 Process simulation for recombinant protein production: cost estimation and sensitivity analysis for heparinase I expressed in Escherichia coli. Biotechnol Bioeng 1997 0.84
35 Specific plate assay for bacterial heparinase. Appl Environ Microbiol 1990 0.84
36 Acetate kinase production by Escherichia coli during steady-state and transient growth in continuous culture. J Bacteriol 1978 0.83
37 Measurement and synthesis of insoluble and soluble dextran by Streptococcus mutans. J Dent Res 1977 0.83
38 Removal of the anticoagulant activities of the low molecular weight heparin fractions and fragments with flavobacterial heparinase. Thromb Res 1986 0.82
39 Immobilized mammalian cell cultivation in hollow fiber bioreactors. Biotechnol Adv 1990 0.81
40 A continuous assay for an intracellular enzyme: the analysis of acetate kinase in Escherichia coli. Anal Biochem 1976 0.81
41 Pencillin amidase production by Bacillus megaterium. Biotechnol Bioeng 1973 0.81
42 Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis. Biochemistry 1996 0.81
43 Microbial fermentative preparation of L-[15N2]lysine and its tracer: application to serum amino acid kinetic studies. Anal Biochem 1983 0.80
44 The release of heparinase from the periplasmic space of Flavobacterium heparinum by three-step osmotic shock. Appl Biochem Biotechnol 1991 0.80
45 Regional heparinization via simultaneous separation and reaction in a novel Taylor-Couette flow device. Biotechnol Bioeng 1999 0.80
46 Effects of oxygen on recombinant protein expression. Biotechnol Prog 1998 0.79
47 Thermophilic mixed culture of bacteria utilizing methanol for growth. Appl Microbiol 1974 0.78
48 Production of ethanol by Clostridium thermosaccharolyticum: I. Effect of cell recycle and environmental parameters. Biotechnol Bioeng 1989 0.78
49 Methanol Inhibition in Continuous Culture of Hansenula polymorpha. Appl Environ Microbiol 1981 0.78
50 Mammalian cell and protein distributions in ultrafiltration hollow fiber bioreactors. Biotechnol Bioeng 1990 0.78
51 Computer-aided baker's yeast fermentations. Biotechnol Bioeng 1977 0.77
52 Complex flexibility of the transforming growth factor beta superfamily. Proc Natl Acad Sci U S A 1995 0.77
53 Intracellular lytic enzyme systems and their use for disruption of Escherichia coli. Adv Biochem Eng Biotechnol 1990 0.77
54 Growth monitoring and control through computer-aided on-line mass balancing in a fed-batch penicillin fermentation. Biotechnol Bioeng 1983 0.76
55 Production of Maltase by Wild-Type and a Constitutive Mutant of Saccharomyces italicus. Appl Environ Microbiol 1982 0.75
56 Expression of a proline-enriched protein in Escherichia coli. Appl Environ Microbiol 1982 0.75
57 Sulfur regulation of heparinase and sulfatases in Flavobacterium heparinum. Appl Environ Microbiol 1986 0.75
58 Formation of Short-Chain Fatty Acids from H(2) and CO(2) by a Mixed Culture of Bacteria. Appl Environ Microbiol 1981 0.75
59 Enzyme catalysis in the presence of nonaqueous solvents using chloroperoxidase. Biotechnol Bioeng 1974 0.75
60 Design and evaluation of control strategies for high cell density fermentations. Biotechnol Bioeng 1992 0.75
61 Fermentation monitoring. Curr Opin Biotechnol 1992 0.75
62 Theoretical conversion yields for penicillin synthesis. Biotechnol Bioeng 1977 0.75
63 In vivo activity of microbial heparinase. Trans Am Soc Artif Intern Organs 1982 0.75
64 Optimization and simulation of continuous affinity-recycle extraction (care). Bioseparation 1990 0.75
65 Kinetics of immobilized heparinase in human blood. Ann Biomed Eng 1993 0.75
66 Acrylate fermentations. Basic Life Sci 1981 0.75
67 Studies on the overproduction of indole-containing metabolites by a methanol-utilizing yeast : Hansenula polymorpha. Appl Biochem Biotechnol 1982 0.75
68 Oxygen limitation on L-serine production in a hollow-fiber bioreactor. Appl Biochem Biotechnol 1986 0.75
69 Fermentation science: basic and applied research needs. Roundtable discussion. Basic Life Sci 1981 0.75
70 Immobilization of oligonucleotides on a large pore support for plasmid purification by triplex affinity interaction. Bioseparation 1999 0.75
71 Gene therapy: biotech's n + 1 technology. What they are teaching at MIT's Sloan School of Management. Biotechnology (N Y) 1994 0.75
72 Biotechnology has been associated with the pharmaceutical and brewing industries. Biotechnol Adv 1984 0.75
73 An in vitro assay to measure early calcium loss from surface enamel. J Dent Res 1974 0.75
74 Large scale preparation and characterization of mucopolysaccharase contamination free heparinase. Appl Biochem Biotechnol 1988 0.75
75 Production of ethanol by Clostridium thermosaccharolyticum: II. A quantitative model describing product distributions. Biotechnol Bioeng 1989 0.75
76 Growth monitoring and control in complex medium: a case study employing fed-batch penicillin fermentation and computer-aided on-line mass balancing. Biotechnol Bioeng 1983 0.75
77 Experiments and calculations concerning a thermal enzyme probe. Biochim Biophys Acta 1976 0.75
78 Heparinase: in vivo activity and immunogenicity in rabbits. J Lab Clin Med 1983 0.75
79 Esterification-coupled extraction of organic acids: partition enhancement and underlying reaction and distribution equilibria. Biotechnol Bioeng 1989 0.75
80 An overview of continuous protein purification processes. Biotechnol Adv 1990 0.75
81 Measurement of heat evolution and correlation with oxygen consumption during microbial growth. Reprinted from Biotechnology and Bioengineering, Vol. XI, Issue 3, Pages 269-281 (1968). Biotechnol Bioeng 2000 0.75
82 Continuous monitoring of nitrogenase activity in Azotobacter vinelandii fermentation using off-gas mass spectrometry. Biotechnol Bioeng 1995 0.75