Published in Hum Mol Genet on December 01, 1993
Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol (2001) 1.05
Epidermolysis bullosa simplex: a keratin 5 mutation is a fully dominant allele in epidermal cytoskeleton function. Am J Hum Genet (1995) 0.77
p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (1999) 13.21
Rescue of measles viruses from cloned DNA. EMBO J (1995) 7.87
Molecular and cellular biology of intermediate filaments. Annu Rev Biochem (1988) 5.48
Production and auto-induction of transforming growth factor-alpha in human keratinocytes. Nature (1987) 4.19
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55
Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature (1983) 3.51
Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Science (1995) 3.44
Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol (1989) 3.21
The molecular biology of intermediate filaments. Cell (1985) 3.17
Hydroxyurea-induced leg ulceration in 14 patients. Ann Intern Med (1998) 3.03
Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet (2001) 3.00
Multiple defects and perinatal death in mice deficient in follistatin. Nature (1995) 2.96
Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell (1978) 2.87
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium. Cancer Res (1986) 2.83
Functional analysis of activins during mammalian development. Nature (1995) 2.71
Overexpression of transforming growth factor alpha in psoriatic epidermis. Science (1989) 2.63
Role of molecular conformation in determining the electrophoretic properties of polynucleotides in agarose-acrylamide composite gels. Biochemistry (1971) 2.59
Structure and expression of a chicken gene coding for U1 RNA. Cell (1981) 2.51
Identification of a major keratinocyte cell envelope protein, loricrin. Cell (1990) 2.25
Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol (2000) 2.22
DNA probes specific for Entamoeba histolytica possessing pathogenic and nonpathogenic zymodemes. Infect Immun (1989) 2.22
Galactomannan antigenemia and antigenuria in aspergillosis: studies in patients and experimentally infected rabbits. J Infect Dis (1987) 2.18
Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival. Immunity (2001) 2.11
Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling. FASEB J (2000) 2.09
Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum. J Mol Med (Berl) (2000) 2.04
Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase. J Biol Chem (1997) 2.00
Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem (1984) 1.96
Quality of care and outcomes of adults with asthma treated by specialists and generalists in managed care. Arch Intern Med (2001) 1.96
A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin. Mol Cell Biol (1991) 1.93
Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem (1991) 1.91
Antibody responses in nasal secretions and serum of elderly persons following local or parenteral administration of inactivated influenza virus vaccine. J Immunol (1969) 1.91
Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res (2000) 1.88
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature (1986) 1.86
Role of molecular conformation in determining the electrophoretic properties of polynucleotides in agarose-acrylamide gels. II. Biochemistry (1972) 1.86
Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A (1985) 1.82
Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis. Nat Genet (1998) 1.82
Retracted Functional and nonfunctional measles virus matrix genes from lethal human brain infections. J Virol (1991) 1.82
Integrated control of growth and differentiation of normal human prokeratinocytes cultured in serum-free medium: clonal analyses, growth kinetics, and cell cycle studies. J Cell Physiol (1984) 1.81
Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus. Arch Dermatol (2001) 1.79
Possible role of transforming growth factor alpha in the pathogenesis of Ménétrier's disease: supportive evidence form humans and transgenic mice. Gastroenterology (1992) 1.77
Definition of the 5' and 3' ends of transcripts of the ovalbumin gene. Cell (1980) 1.77
Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis. Science (1992) 1.73
Hydroxyurea dermopathy: a unique lichenoid eruption complicating long-term therapy with hydroxyurea. J Am Acad Dermatol (1997) 1.68
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice. Proc Natl Acad Sci U S A (1993) 1.68
Analysis of the cornified cell envelope in lamellar ichthyosis. Arch Dermatol (1993) 1.67
A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein. Genes Dev (1994) 1.65
Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A (1983) 1.64
Pulmonary and mediastinal glomus tumors--report of five cases including a pulmonary glomangiosarcoma: a clinicopathologic study with literature review. Am J Surg Pathol (2000) 1.64
Lamellar ichthyosis is genetically heterogeneous--cases with normal keratinocyte transglutaminase. J Invest Dermatol (1995) 1.61
The peritrophic membrane as a barrier: its penetration by Plasmodium gallinaceum and the effect of a monoclonal antibody to ookinetes. Exp Parasitol (1991) 1.61
A homozygous nonsense mutation in the beta 3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa. Genomics (1994) 1.59
Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. Biochemistry (1978) 1.59
WHIM syndrome, an autosomal dominant disorder: clinical, hematological, and molecular studies. Am J Med Genet (2000) 1.58
Successful treatment of gastrointestinal vasculitis due to systemic lupus erythematosus with intravenous pulse cyclophosphamide: a clinical case report and review of the literature. Br J Rheumatol (1998) 1.56
An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol (2001) 1.55
Tissue plasminogen activator for treatment of livedoid vasculitis. Mayo Clin Proc (1992) 1.53
Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ (1990) 1.53
Ophthalmic abnormalities in patients with cutaneous T-cell lymphoma. Ophthalmology (1999) 1.53
The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins. Proc Natl Acad Sci U S A (1984) 1.52
Mutations in the gene encoding SLURP-1 in Mal de Meleda. Hum Mol Genet (2001) 1.50
Expression of p53 protein in benign and malignant epidermal pathologic conditions. J Am Acad Dermatol (1993) 1.50
Cell density and culture factors regulate keratinocyte commitment to differentiation and expression of suprabasal K1/K10 keratins. J Invest Dermatol (1995) 1.48
Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci U S A (1997) 1.47
Activating BRAF mutations in eruptive melanocytic naevi. Br J Dermatol (2010) 1.46
Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol (2000) 1.44
New techniques for the in vitro culture of human skin keratinocytes and perspectives on their use for grafting of patients with extensive burns. Mayo Clin Proc (1986) 1.44
Efficacy of vitamin D3 derivatives in the treatment of psoriasis vulgaris: a preliminary report. Mayo Clin Proc (1993) 1.43
Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits. J Biol Chem (1985) 1.43
Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A (1999) 1.42
Ultrastructural connective tissue abnormalities in patients with spontaneous cervicocerebral artery dissections. Ann Neurol (1998) 1.42
Trichothiodystrophy: update on the sulfur-deficient brittle hair syndromes. J Am Acad Dermatol (2001) 1.40
Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family. J Biol Chem (1994) 1.40
A 500-kb region on chromosome 16p13.1 contains the pseudoxanthoma elasticum locus: high-resolution mapping and genomic structure. J Mol Med (Berl) (2000) 1.39
[Epidermolysis bullosa dystrophica inversa: report on 2 sisters]. Hautarzt (1976) 1.39
Generation and properties of measles virus mutations typically associated with subacute sclerosing panencephalitis. Ann N Y Acad Sci (1994) 1.39
Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev (1997) 1.39
Treatment patterns among adult patients with asthma: factors associated with overuse of inhaled beta-agonists and underuse of inhaled corticosteroids. Arch Intern Med (2000) 1.39
Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin. Mol Psychiatry (2006) 1.38
Fibrillar protein deposits with tubular substructure in a systemic disease beginning as cutis laxa. Arch Dermatol (1993) 1.38
Prenatal diagnosis of junctional epidermolysis bullosa Herlitz type. Lancet (1989) 1.38
Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem (1985) 1.38
NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res (2000) 1.37
Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei. Nature (1979) 1.36
Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed. Biochemistry (1980) 1.36
Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature. J Am Acad Dermatol (1988) 1.35
A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest (1997) 1.35
Primary structure of tyrosinase from Streptomyces glaucescens. Biochemistry (1985) 1.35
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene (2006) 1.35
Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog (1993) 1.35
Mutations in the COL5A1 gene are causal in the Ehlers-Danlos syndromes I and II. Am J Hum Genet (1997) 1.33
Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts. FASEB J (2000) 1.32