Published in Growth Regul on February 01, 1994
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc Natl Acad Sci U S A (1999) 2.62
Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci U S A (2001) 2.35
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. Proc Natl Acad Sci U S A (2000) 1.90
IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth. Proc Natl Acad Sci U S A (2007) 1.88
Insulin-like growth factor-1 and delirium in critically ill mechanically ventilated patients: a preliminary investigation. Int Psychogeriatr (2011) 1.44
Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone. J Clin Invest (1995) 1.27
Role of oestrogen receptors alpha and beta in immune organ development and in oestrogen-mediated effects on thymus. Immunology (2001) 1.25
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice. Proc Natl Acad Sci U S A (2003) 1.11
Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy. J Physiol (2008) 1.11
Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study. J Clin Invest (1996) 1.00
Sex, Sport, IGF-1 and the Community Effect in Height Hypothesis. Int J Environ Res Public Health (2015) 0.98
Mesenchymally-derived insulin-like growth factor 1 provides a paracrine stimulus for trophoblast migration. BMC Dev Biol (2002) 0.98
A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGF-binding protein-3 complex to preterm infants. Pediatr Res (2009) 0.95
Size at birth and adult fat mass in twin sheep are determined in early gestation. J Physiol (2011) 0.92
White matter damage after chronic subclinical inflammation in newborn mice. J Child Neurol (2009) 0.90
The first-year growth response to growth hormone treatment predicts the long-term prepubertal growth response in children. BMC Med Inform Decis Mak (2009) 0.89
Models predicting the growth response to growth hormone treatment in short children independent of GH status, birth size and gestational age. BMC Med Inform Decis Mak (2007) 0.89
Growth factor deficiency in patients with ataxia telangiectasia. Clin Exp Immunol (2005) 0.87
Overexpression of lymphotoxin in T cells induces fulminant thymic involution. Am J Pathol (2008) 0.83
Longitudinal infusion of a complex of insulin-like growth factor-I and IGF-binding protein-3 in five preterm infants: pharmacokinetics and short-term safety. Pediatr Res (2012) 0.83
Differential changes in insulin-like growth factors and their binding proteins following asphyxia in the preterm fetal sheep. J Physiol (2001) 0.81
United States multicenter study of factors predicting the persistence of GH deficiency during the transition period between childhood and adulthood. Int J Pediatr Endocrinol (2013) 0.80
Copy number variants in short children born small for gestational age. Horm Res Paediatr (2014) 0.80
Bone mineral density in partially recovered early onset anorexic patients - a follow-up investigation. Child Adolesc Psychiatry Ment Health (2010) 0.79
Parenteral administration of twin-bearing ewes with L-arginine enhances the birth weight and brown fat stores in sheep. Springerplus (2013) 0.76
Loss of the pregnancy-induced rise in cortisol concentrations in the ewe impairs the fetal insulin-like growth factor axis. Reprod Fertil Dev (2011) 0.76
Insulin-Like Growth Factor 1 (IGF-1) in Parkinson's Disease: Potential as Trait-, Progression- and Prediction Marker and Confounding Factors. PLoS One (2016) 0.76
Impairment of bone health in pediatric patients with hemolytic anemia. PLoS One (2014) 0.76
Measuring growth hormone and insulin-like growth factor-I in infants: what is normal? Pediatr Endocrinol Rev (2013) 0.76
The Auxological and Biochemical Continuum of Short Children Born Small for Gestational Age (SGA) or with Normal Birth Size (Idiopathic Short Stature). Int J Pediatr Endocrinol (2010) 0.76
Reduced cortisol and metabolic responses of thin ewes to an acute cold challenge in mid-pregnancy: implications for animal physiology and welfare. PLoS One (2012) 0.75
Bone deficits in parenteral nutrition-dependent infants and children with intestinal failure are attenuated when accounting for slower growth. J Pediatr Gastroenterol Nutr (2013) 0.75
Development and verification of a pharmacokinetic model to optimize physiologic replacement of rhIGF-1/rhIGFBP-3 in preterm infants. Pediatr Res (2016) 0.75
Association between serum insulin-like growth factor I or IGF-binding protein 3 and estimated glomerular filtration rate: results of a population-based sample. BMC Nephrol (2012) 0.75
Reference Values for IGF-I Serum Concentrations: Comparison of Six Immunoassays. J Clin Endocrinol Metab (2016) 0.75
Determining the normal range for IGF-I, IGFBP-3, and ALS: new reference data based on current internal standards. Wien Med Wochenschr (2014) 0.75
IGF-binding protein-3 fragments in plasma of a child with acute renal failure. Pediatr Nephrol (2004) 0.75
Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition. Am J Physiol Endocrinol Metab (2000) 3.52
Neonatal leptin treatment reverses developmental programming. Endocrinology (2005) 3.51
Sedentary behavior during postnatal life is determined by the prenatal environment and exacerbated by postnatal hypercaloric nutrition. Am J Physiol Regul Integr Comp Physiol (2003) 1.86
Chronic maternal undernutrition in the rat leads to delayed postnatal growth and elevated blood pressure of offspring. Pediatr Res (1996) 1.36
A model of intrauterine growth retardation caused by chronic maternal undernutrition in the rat: effects on the somatotrophic axis and postnatal growth. J Endocrinol (1996) 1.26
Dysregulation of the adipoinsular axis -- a mechanism for the pathogenesis of hyperleptinemia and adipogenic diabetes induced by fetal programming. J Endocrinol (2001) 1.11
IGF-I treatment reduces hyperphagia, obesity, and hypertension in metabolic disorders induced by fetal programming. Endocrinology (2001) 1.08
Inverse changes in fetal insulin-like growth factor (IGF)-1 and IGF binding protein-1 in association with higher birth weight in maternal diabetes. Clin Endocrinol (Oxf) (2007) 1.05
Fetal growth and placental function. Mol Cell Endocrinol (1998) 1.02
The effect of a chronic maternal cortisol infusion on the late-gestation fetal sheep. J Endocrinol (2002) 1.00
Growth hormone as a neuronal rescue factor during recovery from CNS injury. Neuroscience (2001) 1.00
Insulin-like growth factor-1 (IGF-1) in mice reduces weight loss during starvation. Endocrinology (1989) 0.97
A role for the somatotropic axis in neural development, injury and disease. J Pediatr Endocrinol Metab (2000) 0.97
Enteral IGF-I enhances fetal growth and gastrointestinal development in oesophageal ligated fetal sheep. J Endocrinol (1999) 0.95
Adult growth hormone treatment reduces hypertension and obesity induced by an adverse prenatal environment. J Endocrinol (2002) 0.92
Glucose but not a mixed amino acid infusion regulates plasma insulin-like growth factor-I concentrations in fetal sheep. Pediatr Res (1993) 0.92
Improvement of diagnostic criteria in growth hormone insensitivity syndrome: solutions and pitfalls. Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes. Acta Paediatr Suppl (1994) 0.90
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) treatment of the GH-deficient dwarf rat: differential effects on IGF-I transcription start site expression in hepatic and extrahepatic tissues and lack of effect on type I IGF receptor mRNA expression. Mol Cell Endocrinol (1994) 0.89
Impaired sperm characteristics in postpubertal growth-hormone-deficient dwarf (dw/dw) rats. Anim Reprod Sci (1997) 0.88
Increased milk levels of insulin-like growth factor 1 (IGF-1) for the identification of bovine somatotropin (bST) treated cows. Analyst (1998) 0.87
Blood plasma concentrations of insulin-like growth factor-I (IGF-I) in resting standardbred horses. Vet J (2002) 0.87
Expression and regulation of insulin-like growth factor-I in the rat incisor. Growth Factors (1993) 0.86
Synergistic effect of insulin-like growth factor-I administration on the protein-sparing effects of total parenteral nutrition in fasted lambs. Endocrinology (1992) 0.86
Effects of long-term administration of pituitary-derived bovine growth hormone and estradiol on growth in steers. J Anim Sci (1990) 0.86
Fetal insulin-like growth factor (IGF)-I and IGF-II are regulated differently by glucose or insulin in the sheep fetus. Reprod Fertil Dev (1996) 0.86
Elevating maternal insulin-like growth factor-I in mice and rats alters the pattern of fetal growth by removing maternal constraint. J Endocrinol (1992) 0.85
Administration of growth hormone or IGF-I to pregnant rats on a reduced diet throughout pregnancy does not prevent fetal intrauterine growth retardation and elevated blood pressure in adult offspring. J Endocrinol (1999) 0.85
Growth restriction in dexamethasone-treated preterm infants may be mediated by reduced IGF-I and IGFBP-3 plasma concentrations. Clin Endocrinol (Oxf) (2001) 0.85
The fetal somatotropic axis during long term maternal undernutrition in sheep: evidence for nutritional regulation in utero. Endocrinology (1995) 0.85
Maternal undernutrition during the periconceptual period increases plasma taurine levels and insulin response to glucose but not arginine in the late gestational fetal sheep. Endocrinology (2001) 0.84
IGF-I treatment increases motility and improves morphology of immature spermatozoa in the GH-deficient dwarf (dw/dw) rat. Growth Horm IGF Res (1999) 0.84
The response of the hepatic insulin-like growth factor system to growth hormone and dexamethasone in calves. J Endocrinol (2003) 0.83
The effect of maternal starvation on plasma insulin-like growth factor I concentrations in the late gestation ovine fetus. Pediatr Res (1990) 0.83
Differential changes in insulin-like growth factors and their binding proteins following asphyxia in the preterm fetal sheep. J Physiol (2001) 0.81
Effects of recombinant IGF-I on protein and glucose metabolism in rTNF-infused lambs. Am J Physiol (1991) 0.81
Metabolic consequences of intrauterine growth retardation. Acta Paediatr Suppl (1996) 0.81
The endocrine role of insulin-like growth factor I. Acta Paediatr Scand Suppl (1991) 0.81
Receptors for insulin-like growth factor-II in the growing tip of the deer antler. J Endocrinol (1993) 0.80
Effects of melatonin implants on insulin-like growth factor 1 in male red deer (Cervus elaphus). Gen Comp Endocrinol (1992) 0.80
Insulin-like growth factors and their binding proteins in patients with growth hormone receptor deficiency: suggestions for new diagnostic criteria. The Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes. Acta Paediatr Suppl (1992) 0.80
Anabolic and cardiovascular effects of recombinant human growth hormone in surgical patients with sepsis. Br J Surg (1996) 0.80
Alterations in the neural growth hormone axis following hypoxic-ischemic brain injury. Brain Res Mol Brain Res (1999) 0.80
Fetal rat lung epithelium has a functional growth hormone receptor coupled to tyrosine kinase activity and insulin-like growth factor binding protein-2 production. J Mol Endocrinol (1998) 0.80
Fetal programming of insulin-like growth factor (IGF)-I and IGF-binding protein-3: evidence for an altered response to undernutrition in late gestation following exposure to periconceptual undernutrition in the sheep. J Endocrinol (1998) 0.80
Tissue distribution and ontogeny of growth hormone receptor messenger ribonucleic acid and ligand binding to hepatic tissue in the midgestation sheep fetus. Endocrinology (1993) 0.80
Photoperiod associated changes in insulin-like growth factor-I in reindeer. Endocrinology (1991) 0.79
Plasma clearance of radiolabelled IGF-1 in the late gestation ovine fetus. J Dev Physiol (1990) 0.79
Growth hormone increases breast milk volumes in mothers of preterm infants. Pediatrics (1996) 0.79
Developmental patterns of plasma insulin-like growth factor-1 concentrations in sheep. Domest Anim Endocrinol (1990) 0.79
The somatotrophic axis in young steers: influence of nutritional status on pulsatile release of growth hormone and circulating concentrations of insulin-like growth factor 1. J Endocrinol (1986) 0.79
Reproductive performance and fetal growth in female mice from lines divergently selected on the basis of plasma IGF-1 concentrations. J Reprod Fertil (1989) 0.79
The effect of the frequency of subcutaneous insulin-like growth factor-1 administration on weight gain in growth hormone deficient mice. Horm Metab Res (1991) 0.79
Human insulin-like growth factor I (IGF-I) produced in the mammary glands of transgenic rabbits: yield, receptor binding, mitogenic activity, and effects on IGF-binding proteins. Endocrinology (1997) 0.79
Body growth, carcass composition, and endocrine changes in lambs chronically treated with recombinantly derived insulin-like growth factor-I. Endocrinology (1992) 0.79
Insulin-like growth factors (IGFs) and IGF binding proteins in chronic renal failure: evidence for reduced secretion of IGFs. Acta Paediatr Scand Suppl (1991) 0.78
Placental development and fetal growth in growth hormone-treated ewes. Growth Horm IGF Res (1999) 0.78
Consequences of maternal undernutrition for fetal and postnatal hepatic insulin-like growth factor-I, growth hormone receptor and growth hormone binding protein gene regulation in the rat. J Mol Endocrinol (1998) 0.78
Growth allometry of organs, muscles and bones in mice from lines divergently selected on the basis of plasma insulin-like growth factor-I. Growth Dev Aging (1992) 0.78
Pharmacokinetics of glycine-proline-glutamate, the N-terminal tripeptide of insulin-like growth factor-1, in rats. Anal Biochem (2003) 0.78
Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd International Symposium on Insulin-like Growth Factors. J Endocrinol (1994) 0.78
Influence of nutrition and bovine growth hormone (GH) on hepatic GH binding, insulin-like growth factor-I and growth of lambs. J Endocrinol (1991) 0.78
Passive immunization against circulating insulin-like growth factor-I (IGF-I) increases protein catabolism in lambs: evidence for a physiological role for circulating IGF-I. J Endocrinol (1992) 0.78
Presence of insulin-like growth factor-I receptors and absence of growth hormone receptors in the antler tip. Endocrinology (1992) 0.78
Circulating insulin-like growth factor II/mannose-6-phosphate receptor and insulin-like growth factor binding proteins in fetal sheep plasma are regulated by glucose and insulin. Eur J Endocrinol (1994) 0.78
Fetal growth in late gestation--a constrained pattern of growth. Acta Paediatr Scand Suppl (1990) 0.78
Periconceptual undernutrition resets plasma IGFBP levels and alters the response of IGFBP-1, IGFBP-3 and IGF-1 to subsequent maternal undernutrition in fetal sheep. Prog Growth Factor Res (1995) 0.77
Ovine placental lactogen lacks direct somatogenic and anticatabolic actions in the postnatal lamb. J Endocrinol (1995) 0.77
The effects of octreotide on GH receptor and IGF-I expression in the GH-deficient rat. J Endocrinol (1996) 0.77
IGF-I and IGF-binding protein-3 in plasma of GH-deficient rats. J Endocrinol (1996) 0.77
Differential effects of maternal ovine placental lactogen and growth hormone (GH) administration on GH receptor, insulin-like growth factor (IGF)-1 and IGF binding protein-3 gene expression in the pregnant and fetal sheep. Growth Regul (1996) 0.77
Comparison of the effects of administration of recombinant bovine growth hormone or N-Met insulin-like growth factor-I to lactating goats. J Endocrinol (1989) 0.77
Effects of oral IGF-I or IGF-II on digestive organ growth in newborn piglets. Biol Neonate (1994) 0.77
Ontogenic differences in the nutritional regulation of circulating IGF binding proteins in sheep plasma. Acta Endocrinol (Copenh) (1992) 0.77
A homologous radioimmunoassay for ovine insulin-like growth factor-binding protein-2: ontogenesis and the response to growth hormone, placental lactogen and insulin-like growth factor-I treatment in sheep. J Endocrinol (1995) 0.77
A possible role for IGE-II: evidence in sheep for in vivo regulation of IGF-I mediated protein anabolism. Endocrinology (1992) 0.77
Influence of fetal and maternal genotype for circulating insulin-like growth factor I on fetal growth in mice. J Reprod Fertil (1994) 0.77
The nutritional regulation of circulating placental lactogen in fetal sheep. Pediatr Res (1992) 0.77
Pretreatment with bovine growth hormone is as effective as treatment during metabolic stress to reduce catabolism in fasted lambs. Endocrinology (1996) 0.76
Physiology of the somatotropic axis with particular reference to the ruminant. J Dairy Sci (1987) 0.76
20-kDa placental hGH-V has diminished diabetogenic and lactogenic activities compared with 22-kDa hGH-N while retaining antilipogenic activity. Am J Physiol Endocrinol Metab (2009) 0.76
The metabolic effects of endotoxin are differentially affected by the pattern of GH administration in the rat. J Endocrinol (2001) 0.76
Feed restriction in young bulls alters the onset of puberty in relationship with plasma insulin-like growth factor-I (IGF-I) and IGF-binding proteins. Domest Anim Endocrinol (2000) 0.76
Exogenous GH infusion to late-gestational fetal sheep does not alter fetal growth and metabolism. J Endocrinol (2000) 0.76
The effects of ovine placental lactogen infusion on metabolites, insulin-like growth factors and binding proteins in the fetal sheep. J Endocrinol (1995) 0.76
Serum insulin-like growth factor-I concentrations in late middle age: no association with birthweight in three UK cohorts. Acta Physiol Scand (2004) 0.76
Growth hormone stimulates galactopoiesis in healthy lactating women. Acta Endocrinol (Copenh) (1992) 0.76
Chronic treatment with bovine growth hormone upregulates high-affinity hepatic somatotropic receptors in sheep. Acta Endocrinol (Copenh) (1991) 0.75
Responses of young energy-restricted sheep to chronically administered insulin-like growth factor I (IGF-I): evidence that IGF-I suppresses the hepatic growth hormone receptor. Endocrinology (1996) 0.75
Role of testosterone in regulating the growth of mice from lines selected for low vs high plasma insulin-like growth factor-I concentrations. Acta Endocrinol (Copenh) (1989) 0.75
Gonadal suppression by a GnRH analogue does not alter somatic growth in rats with complete GH deficiency. J Endocrinol (2000) 0.75
Upregulation of GH receptor and GH binding protein during pregnancy in the GH deficient rat. Endocrine (1995) 0.75
Ovine placental lactogen is a potent somatogen in the growth hormone (GH)-deficient rat: comparison of somatogenic activity with bovine GH. Endocrinology (1992) 0.75
The circulating molecular weight forms of infused recombinant insulin-like growth factor-I and effects on glucose and fat metabolism in lambs. Diabetologia (1991) 0.75
Ontogeny of IGF-I responsiveness to bGH in young lambs. Domest Anim Endocrinol (1999) 0.75
Replicated selection for insulin-like growth factor-1 and body weight in mice. Theor Appl Genet (1991) 0.75
Regulation of the cell surface growth hormone receptor. Acta Paediatr Scand Suppl (1990) 0.75
The interrelationship between and the regulation of hepatic growth hormone receptors and circulating GH binding protein in the pig. Acta Endocrinol (Copenh) (1992) 0.75
Developmental patterns of plasma insulin-like growth factor-I (IGF-I) and body growth in mice from lines divergently selected on the basis of plasma IGF-I. J Endocrinol (1990) 0.75
IGFBP-2 expression in liver and mammary tissue in lactating and pregnant ewes. Acta Endocrinol (Copenh) (1993) 0.75
Disappearance of labelled IGF-2 from plasma of the ovine fetus in late gestation. J Dev Physiol (1990) 0.75