| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport.
|
J Membr Biol
|
1981
|
4.79
|
|
2
|
Potential energy barriers to ion transport within lipid bilayers. Studies with tetraphenylborate.
|
Biophys J
|
1975
|
3.56
|
|
3
|
Ion movement through gramicidin A channels. Single-channel measurements at very high potentials.
|
Biophys J
|
1983
|
3.47
|
|
4
|
Energetics of inclusion-induced bilayer deformations.
|
Biophys J
|
1998
|
3.19
|
|
5
|
Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step.
|
Biophys J
|
1983
|
3.15
|
|
6
|
Gramicidin channels.
|
Annu Rev Physiol
|
1984
|
3.00
|
|
7
|
Surface charges and ion channel function.
|
Annu Rev Physiol
|
1991
|
2.90
|
|
8
|
Ion movement through gramicidin A channels. Interfacial polarization effects on single-channel current measurements.
|
Biophys J
|
1983
|
2.87
|
|
9
|
Electrostatic interactions among hydrophobic ions in lipid bilayer membranes.
|
Biophys J
|
1978
|
2.80
|
|
10
|
Effect of phloretin on the permeability of thin lipid membranes.
|
J Gen Physiol
|
1976
|
2.72
|
|
11
|
Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block.
|
J Gen Physiol
|
1987
|
2.55
|
|
12
|
Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association.
|
Science
|
1990
|
2.31
|
|
13
|
Membrane stiffness and channel function.
|
Biochemistry
|
1996
|
2.19
|
|
14
|
Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration.
|
Biochemistry
|
1991
|
2.09
|
|
15
|
Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers.
|
J Gen Physiol
|
1994
|
2.06
|
|
16
|
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.
|
Biophys J
|
1984
|
2.04
|
|
17
|
Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels.
|
Biophys J
|
1999
|
2.01
|
|
18
|
Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A.
|
Biophys J
|
1986
|
1.97
|
|
19
|
Ion movement through gramicidin A channels. On the importance of the aqueous diffusion resistance and ion-water interactions.
|
Acta Physiol Scand Suppl
|
1980
|
1.96
|
|
20
|
On the importance of atomic fluctuations, protein flexibility, and solvent in ion permeation.
|
J Gen Physiol
|
2004
|
1.88
|
|
21
|
Gramicidin channel kinetics under tension.
|
Biophys J
|
1998
|
1.82
|
|
22
|
Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence.
|
J Mol Biol
|
1990
|
1.80
|
|
23
|
Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity.
|
Mol Pharmacol
|
2005
|
1.70
|
|
24
|
Lipid bilayer electrostatic energy, curvature stress, and assembly of gramicidin channels.
|
Biochemistry
|
1997
|
1.61
|
|
25
|
Induction of conductance heterogeneity in gramicidin channels.
|
Biochemistry
|
1989
|
1.58
|
|
26
|
Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures.
|
J Gen Physiol
|
1987
|
1.57
|
|
27
|
Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature.
|
Biophys J
|
2000
|
1.52
|
|
28
|
Kinetics of ion movement mediated by carriers and channels.
|
Methods Enzymol
|
1989
|
1.46
|
|
29
|
Cholesterol-induced protein sorting: an analysis of energetic feasibility.
|
Biophys J
|
2003
|
1.45
|
|
30
|
Amino acid substitutions and ion channel function. Model-dependent conclusions.
|
Biophys J
|
1992
|
1.45
|
|
31
|
Design and characterization of gramicidin channels.
|
Methods Enzymol
|
1999
|
1.35
|
|
32
|
On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer.
|
Biophys J
|
1992
|
1.34
|
|
33
|
Graphic representation of the results of kinetic analyses.
|
J Gen Physiol
|
1999
|
1.30
|
|
34
|
The conformational preference of gramicidin channels is a function of lipid bilayer thickness.
|
FEBS Lett
|
1997
|
1.29
|
|
35
|
Chloride--bicarbonate exchange in red blood cells: physiology of transport and chemical modification of binding sites.
|
Philos Trans R Soc Lond B Biol Sci
|
1982
|
1.21
|
|
36
|
On the helix sense of gramicidin A single channels.
|
Proteins
|
1992
|
1.19
|
|
37
|
Monazomycin-induced single channels. I. Characterization of the elementary conductance events.
|
J Gen Physiol
|
1982
|
1.17
|
|
38
|
Gramicidin channels that have no tryptophan residues.
|
Biochemistry
|
1992
|
1.16
|
|
39
|
Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy.
|
J Gen Physiol
|
1993
|
1.15
|
|
40
|
Gramicidin channel function does not depend on phospholipid chirality.
|
Biochemistry
|
1995
|
1.14
|
|
41
|
Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel.
|
J Mol Biol
|
1993
|
1.13
|
|
42
|
Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore.
|
Biophys J
|
1989
|
1.09
|
|
43
|
Electrogenic proton transport in epithelial membranes.
|
J Membr Biol
|
1982
|
1.07
|
|
44
|
Closed state of gramicidin channel detected by X-ray in-plane scattering.
|
Biophys Chem
|
1994
|
1.06
|
|
45
|
Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.
|
Biophys J
|
1992
|
1.05
|
|
46
|
Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels.
|
Biochemistry
|
1990
|
1.03
|
|
47
|
Gramicidin channels in phospholipid bilayers with unsaturated acyl chains.
|
Biophys J
|
1997
|
1.02
|
|
48
|
Gramicidins A, B, and C form structurally equivalent ion channels.
|
Biophys J
|
1990
|
0.98
|
|
49
|
Intrinsic characteristics of the proton pump in the luminal membrane of a tight urinary epithelium. The relation between transport rate and delta mu H.
|
J Gen Physiol
|
1985
|
0.98
|
|
50
|
On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study.
|
Biophys J
|
1987
|
0.97
|
|
51
|
On the adsorption of phloretin onto a black lipid membrane.
|
Biophys J
|
1979
|
0.95
|
|
52
|
Platelet-activating factor is a general membrane perturbant.
|
Biochim Biophys Acta
|
1989
|
0.95
|
|
53
|
Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue.
|
Biophys J
|
1994
|
0.93
|
|
54
|
Steady-state gating of batrachotoxin-modified sodium channels. Variability and electrolyte-dependent modulation.
|
J Gen Physiol
|
1991
|
0.92
|
|
55
|
Structural information from functional measurements: single-channel studies on gramicidin analogues.
|
Biophys J
|
1986
|
0.92
|
|
56
|
A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels.
|
Biophys J
|
1992
|
0.92
|
|
57
|
IFCC recommended reference method for the determination of the substance concentration of ionized calcium in undiluted serum, plasma or whole blood.
|
Clin Chem Lab Med
|
2000
|
0.91
|
|
58
|
Gramicidin single-channel properties show no solvent-history dependence.
|
Biophys J
|
1990
|
0.90
|
|
59
|
Surface charges near the guanidinium neurotoxin binding site.
|
Ann N Y Acad Sci
|
1986
|
0.90
|
|
60
|
Stabilizing effect of D-alanine2 in gramicidin channels.
|
Biochemistry
|
1995
|
0.89
|
|
61
|
Monazomycin-induced single channels. II. Origin of the voltage dependence of the macroscopic conductance.
|
J Gen Physiol
|
1982
|
0.86
|
|
62
|
Voltage-dependent gating of an asymmetric gramicidin channel.
|
Proc Natl Acad Sci U S A
|
1995
|
0.85
|
|
63
|
Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans.
|
Biochemistry
|
1999
|
0.85
|
|
64
|
Voltage-gated ion channels in nociceptors: modulation by cGMP.
|
J Neurophysiol
|
2004
|
0.84
|
|
65
|
The antimicrobial peptide gramicidin S permeabilizes phospholipid bilayer membranes without forming discrete ion channels.
|
Biochim Biophys Acta
|
2008
|
0.82
|
|
66
|
The anion transport protein of the red cell membrane. A zipper mechanism of anion exchange.
|
Tokai J Exp Clin Med
|
1982
|
0.82
|
|
67
|
Oxygen-linked hydrogen ion binding of human hemoglobin. Effects of carbon dioxide and 2,3-diphosphoglycerate. IV. Thermodynamical relationship between the variables.
|
Scand J Clin Lab Invest
|
1972
|
0.81
|
|
68
|
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
|
Biochemistry
|
2000
|
0.81
|
|
69
|
Influence of acylation on the channel characteristics of gramicidin A.
|
Biochemistry
|
1992
|
0.80
|
|
70
|
Carbodiimide modification reduces the conductance and increases the tetrodotoxin sensitivity in batrachotoxin-modified sodium channels.
|
Pflugers Arch
|
1992
|
0.80
|
|
71
|
Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins.
|
Biochemistry
|
1992
|
0.80
|
|
72
|
Helix sense of gramicidin channels as a "nonlocal" function of the primary sequence.
|
J Biol Chem
|
1994
|
0.79
|
|
73
|
The structure, cation binding, transport, and conductance of Gly15-gramicidin A incorporated into SDS micelles and PC/PG vesicles.
|
Biochemistry
|
2003
|
0.79
|
|
74
|
En bloc transplantation of pediatric kidneys into adult patients.
|
Arch Surg
|
1974
|
0.79
|
|
75
|
Functional carboxyl groups in the red cell anion exchange protein. Modification with an impermeant carbodiimide.
|
J Gen Physiol
|
1989
|
0.78
|
|
76
|
Design and characterization of gramicidin channels with side chain or backbone mutations.
|
Novartis Found Symp
|
1999
|
0.77
|
|
77
|
Platelet survival test. An accurate prediction of hyperacute rejection of renal allografts in rabbits.
|
Transplantation
|
1973
|
0.76
|
|
78
|
Effects of glycine substitutions on the structure and function of gramicidin a channels.
|
Biochemistry
|
2006
|
0.76
|
|
79
|
Dimer versus tetramer.
|
Biophys J
|
1992
|
0.75
|
|
80
|
Models for gramicidin channels.
|
Biophys J
|
1992
|
0.75
|
|
81
|
An unusual complication of gastric bypass: perforated antral ulcer.
|
Am J Gastroenterol
|
1982
|
0.75
|
|
82
|
The 52nd annual meeting and symposium of the Society of General Physiologists. Local calcium signaling in cell physiology.
|
J Gen Physiol
|
1999
|
0.75
|
|
83
|
Platelet survival test. A method to detect preimmunization in rabbits.
|
Transplantation
|
1973
|
0.75
|
|
84
|
[Hepatolenticular degeneration, Wilson's disease. A characteristics case with remission under penicillamine therapy].
|
Ugeskr Laeger
|
1969
|
0.75
|
|
85
|
Treatment of extensive renal calculi with extracorporeal surgery and autotransplantation.
|
Urology
|
1976
|
0.75
|
|
86
|
[Hepatolenticular degeneration. Wilson's disease].
|
Ugeskr Laeger
|
1969
|
0.75
|
|
87
|
Occlusion of the axillary artery complicating shoulder dislocation: case report.
|
Mil Med
|
1979
|
0.75
|
|
88
|
Nonoperative management of contained esophageal perforation.
|
Arch Surg
|
1981
|
0.75
|
|
89
|
The Journal of General Physiology.
|
J Gen Physiol
|
1997
|
0.75
|
|
90
|
The 50th Annual Meeting and Symposium of the Society of General Physiologists. Cytoskeletal regulation of membrane function.
|
J Gen Physiol
|
1997
|
0.75
|
|
91
|
Peptide backbone chemistry and membrane channel function: effects of a single amide-to-ester replacement on gramicidin channel structure and function.
|
Biochemistry
|
2001
|
0.75
|