Published in J Clin Invest on July 01, 1995
Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med (2012) 6.15
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol (2005) 5.88
Integrating mechanisms of pulmonary fibrosis. J Exp Med (2011) 3.57
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest (2007) 2.88
Tumor necrosis factor-alpha overexpression in lung disease: a single cause behind a complex phenotype. Am J Respir Crit Care Med (2005) 2.56
TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proc Natl Acad Sci U S A (2006) 2.14
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation. J Leukoc Biol (2011) 1.98
Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts. Am J Pathol (1998) 1.82
Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes. J Clin Invest (1997) 1.74
TNF-alpha receptor knockout mice are protected from the fibroproliferative effects of inhaled asbestos fibers. Am J Pathol (1998) 1.52
Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation. Am J Pathol (1997) 1.50
Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype. Am J Respir Cell Mol Biol (2007) 1.41
Interstitial fibrosis and growth factors. Environ Health Perspect (2000) 1.32
Soluble TNF mediates the transition from pulmonary inflammation to fibrosis. PLoS One (2006) 1.32
Novel therapeutic approaches for pulmonary fibrosis. Br J Pharmacol (2011) 1.24
Noncirrhotic portal fibrosis/idiopathic portal hypertension: APASL recommendations for diagnosis and treatment. Hepatol Int (2007) 1.24
The pulmonary physician in critical care * 6: The pathogenesis of ALI/ARDS. Thorax (2002) 1.22
Progress toward improving animal models for idiopathic pulmonary fibrosis. Am J Med Sci (2011) 1.19
A review of current and novel therapies for idiopathic pulmonary fibrosis. J Thorac Dis (2013) 1.18
Determinants of initiation and progression of idiopathic pulmonary fibrosis. Respirology (2009) 1.16
A critical role for alveolar macrophages in elicitation of pulmonary immune fibrosis. Immunology (2000) 1.15
Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis. J Leukoc Biol (2006) 1.12
TNF-α-stimulated fibroblasts secrete lumican to promote fibrocyte differentiation. Proc Natl Acad Sci U S A (2015) 1.07
Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor. Am J Pathol (1998) 1.07
Cytokine mediated tissue fibrosis. Biochim Biophys Acta (2012) 1.06
Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha. Proc Natl Acad Sci U S A (1997) 1.04
Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation. Biol Blood Marrow Transplant (2006) 1.04
Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase. Mol Biol Cell (2001) 1.02
Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1). J Toxicol Environ Health A (2010) 1.02
Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun. Mol Cell Biol (1998) 1.02
National Cancer Institute-National Heart, Lung and Blood Institute/pediatric Blood and Marrow Transplant Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: long-term organ damage and dysfunction. Biol Blood Marrow Transplant (2011) 1.01
TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells. Gene (2007) 1.00
Retinoic acid fails to reverse emphysema in adult mouse models. Thorax (2004) 0.96
Latent infection by γherpesvirus stimulates profibrotic mediator release from multiple cell types. Am J Physiol Lung Cell Mol Physiol (2010) 0.94
Soluble tumor necrosis factor receptor: enbrel (etanercept) for subacute pulmonary dysfunction following allogeneic stem cell transplantation. Biol Blood Marrow Transplant (2011) 0.94
Tumor necrosis factor-alpha inhibits collagen alpha1(I) gene expression and wound healing in a murine model of cachexia. Am J Pathol (1996) 0.91
Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy. Treat Respir Med (2006) 0.90
Anticytokine approaches in pulmonary fibrosis: bringing factors into focus. Thorax (1997) 0.89
FTS reduces bleomycin-induced cytokine and chemokine production and inhibits pulmonary fibrosis in mice. Clin Exp Immunol (2001) 0.89
Idiopathic pneumonia syndrome after bone marrow transplantation: the role of pre-transplant radiation conditioning and local cytokine dysregulation in promoting lung inflammation and fibrosis. Int J Exp Pathol (2001) 0.89
Toxicogenomic analysis of susceptibility to inhaled urban particulate matter in mice with chronic lung inflammation. Part Fibre Toxicol (2009) 0.89
Effect of pulmonary TNF-α overexpression on mouse isolated skeletal muscle function. Am J Physiol Regul Integr Comp Physiol (2011) 0.88
Reduced tumor necrosis factor-alpha and transforming growth factor-beta1 expression in the lungs of inbred mice that fail to develop fibroproliferative lesions consequent to asbestos exposure. Am J Pathol (1999) 0.88
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α. Am J Physiol Lung Cell Mol Physiol (2014) 0.87
Interstitial lung disease in rheumatoid arthritis in the era of biologics. Pulm Med (2011) 0.86
Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation. Am J Pathol (2010) 0.86
Ascorbic acid pre-treated quartz stimulates TNF-alpha release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation. Respir Res (2009) 0.86
Increased tumor necrosis factor-alpha (TNF-alpha) gene expression in parainfluenza type 1 (Sendai) virus-induced bronchiolar fibrosis. Am J Pathol (1998) 0.84
Tumour necrosis factor-alpha production in fibrosing alveolitis is macrophage subset specific. Respir Res (2001) 0.83
Surfactant protein D inhibits TNF-alpha production by macrophages and dendritic cells in mice. J Allergy Clin Immunol (2008) 0.83
The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice. Clin Exp Immunol (2010) 0.82
MicroRNAs as potential targets for progressive pulmonary fibrosis. Front Pharmacol (2015) 0.81
Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation. J Appl Physiol (1985) (2013) 0.81
Dihydroartemisinin supresses inflammation and fibrosis in bleomycine-induced pulmonary fibrosis in rats. Int J Clin Exp Pathol (2015) 0.81
Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis. Thorax (2012) 0.80
Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody. Toxicol Sci (2015) 0.79
Long-term exposure of chemokine CXCL10 causes bronchiolitis-like inflammation. Am J Respir Cell Mol Biol (2011) 0.78
Inflammatory response mechanisms exacerbating hypoxemia in coexistent pulmonary fibrosis and sleep apnea. Mediators Inflamm (2015) 0.77
Critical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice. Int J Chron Obstruct Pulmon Dis (2016) 0.77
Treatment with etanercept in a patient with rheumatoid arthritis-associated interstitial lung disease. Clin Med Insights Case Rep (2011) 0.76
Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation. Arthritis Res Ther (2016) 0.76
Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate. J Toxicol Pathol (2016) 0.75
Copper Deficiency in the Lungs of TNF-α Transgenic Mice. Front Physiol (2016) 0.75
Posttreatment with Protectin DX ameliorates bleomycin-induced pulmonary fibrosis and lung dysfunction in mice. Sci Rep (2017) 0.75
Myofibroblasts and lung fibrosis induced by carbon nanotube exposure. Part Fibre Toxicol (2016) 0.75
Effects of leflunomide on inflamation and fibrosis in bleomycine induced pulmonary fibrosis in wistar albino rats. J Thorac Dis (2013) 0.75
Effects of mineral fibers on the expression of genes whose product may play a role in fiber pathogenesis. Environ Health Perspect (1997) 0.75
Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway. Int J Nanomedicine (2016) 0.75
Changes in pulmonary histology and exfoliated bronchoalveolar cells induced by in vivo introduction of the tumor necrosis factor-alpha gene. Inflammation (2000) 0.75
Involvement of JNK in TNFα Driven Remodelling. Am J Respir Cell Mol Biol (2016) 0.75
Anti-TNFα Therapy in Inflammatory Lung Diseases bn. Pharmacol Ther (2017) 0.75
Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene (1991) 38.64
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature (1995) 11.89
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J (1991) 8.31
Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science (1985) 7.99
A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol (1986) 6.83
Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors. J Exp Med (1986) 5.09
Endothelial-leukocyte adhesion molecules. Annu Rev Immunol (1993) 4.96
Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci U S A (1991) 4.61
The murine transforming growth factor-beta precursor. J Biol Chem (1986) 3.67
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med (1989) 3.58
Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. Am J Pathol (1994) 3.57
Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes. J Cell Biol (1989) 3.55
Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature (1990) 3.46
Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation. Cell (1987) 3.46
Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol (1991) 2.89
Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis. N Engl J Med (1987) 2.62
Cell and tissue responses to oxidative damage. Lab Invest (1993) 2.45
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. Eur Respir J (1994) 2.41
Platelet-derived growth factor in idiopathic pulmonary fibrosis. J Clin Invest (1990) 2.29
Induction of transforming growth factor-alpha in activated human alveolar macrophages. Cell (1988) 2.13
Molecular cloning of murine intercellular adhesion molecule (ICAM-1). EMBO J (1989) 2.10
Bleomycin-induced pulmonary fibrosis in the rat: inhibition by indomethacin. Am J Pathol (1979) 1.96
Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos. J Cell Biol (1989) 1.88
Compartmentalization of intraalveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis (1989) 1.87
Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proc Natl Acad Sci U S A (1990) 1.54
Nucleotide sequence of the murine TNF locus, including the TNF-alpha (tumor necrosis factor) and TNF-beta (lymphotoxin) genes. Nucleic Acids Res (1987) 1.53
Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis. Am J Pathol (1990) 1.53
Transforming growth factor-alpha: structure and biological activities. J Cell Biochem (1986) 1.50
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med (1992) 1.46
Rat alveolar myofibroblasts acquire alpha-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis. Am J Pathol (1993) 1.44
Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis. Am J Pathol (1993) 1.42
The proteins of the surfactant system. Eur Respir J (1994) 1.40
Presence of platelet-derived growth factor in normal and fibrotic lung is specifically associated with interstitial macrophages, while both interstitial macrophages and alveolar epithelial cells express the c-sis proto-oncogene. Am J Respir Cell Mol Biol (1991) 1.33
Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect. Proc Natl Acad Sci U S A (1992) 1.31
Murine endothelial leukocyte-adhesion molecule 1 is a close structural and functional homologue of the human protein. Eur J Biochem (1992) 1.30
Two SP-C genes encoding human pulmonary surfactant proteolipid. J Biol Chem (1988) 1.23
An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium. Infect Immun (1993) 1.12
The v-sis transforming gene of simian sarcoma virus is a new onc gene of primate origin. Nature (1981) 1.11
Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung. J Histochem Cytochem (1992) 1.11
Expression of tumour necrosis factor-alpha in cryptogenic fibrosing alveolitis. Histopathology (1993) 0.95
A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice. Diabetologia (1994) 0.94
Pulmonary platelet trapping induced by bleomycin: correlation with fibrosis and involvement of the beta 2 integrins. Int J Exp Pathol (1994) 0.94
Patterns of pulmonary fibrosis. Pathol Annu (1986) 0.90
Correlation of tissue-specific methylation with gene inactivity in hepatitis B virus transgenic mice. Jpn J Cancer Res (1990) 0.85
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell (1989) 10.98
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (1987) 7.01
Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med (1989) 6.79
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology (1990) 6.34
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev (2001) 5.67
Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors. J Exp Med (1986) 5.09
Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. Mol Cell Biol (1990) 5.08
Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med (1990) 4.90
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science (1994) 4.81
The gut-associated lymphoid system: nature and properties of the large dividing cells. Eur J Immunol (1974) 4.76
A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med (2001) 4.68
Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex. J Exp Med (1977) 4.59
The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions. J Exp Med (1978) 4.57
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc Natl Acad Sci U S A (1995) 4.28
Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem (2000) 3.95
Diversity of antinuclear antibodies in progressive systemic sclerosis. Anti-centromere antibody and its relationship to CREST syndrome. Arthritis Rheum (1980) 3.87
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem (1997) 3.81
Molecular diversity of the NMDA receptor channel. Nature (1992) 3.76
Massive outbreak of Escherichia coli O157:H7 infection in schoolchildren in Sakai City, Japan, associated with consumption of white radish sprouts. Am J Epidemiol (1999) 3.75
Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med (1991) 3.63
Comparative studies of intracellular transport of secretory proteins. J Cell Biol (1978) 3.62
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease. J Exp Med (1987) 3.62
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med (1989) 3.58
Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature (1990) 3.46
Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation. Cell (1987) 3.46
Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to "nonmuscular" cells. Am J Pathol (1973) 3.36
Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor. Proc Natl Acad Sci U S A (1973) 3.25
Updated Kiel classification for lymphomas. Lancet (1988) 3.25
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity (2001) 3.13
Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice. Proc Natl Acad Sci U S A (1995) 3.08
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci U S A (1989) 3.03
Pathogenesis and reversibility of the pulmonary lesions of oxygen toxicity in monkeys. II. Ultrastructural and morphometric studies. Lab Invest (1969) 3.01
Expression vector system based on the chicken beta-actin promoter directs efficient production of interleukin-5. Gene (1989) 3.00
Mouse thymus-independent and thymus-derived lymphoid cells. I. Immunofluorescent and functional studies. J Exp Med (1972) 2.96
Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94
In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol (1983) 2.91
The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation. J Exp Med (1991) 2.82
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev Biol (1993) 2.79
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol (1994) 2.76
The distribution of large dividing lymph node cells in syngeneic recipient rats after intravenous injection. J Exp Med (1969) 2.76
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. Proc Natl Acad Sci U S A (1993) 2.74
An immunofluorescent study of pathogenic mechanisms in glomerular diseases. N Engl J Med (1966) 2.70
Fatal infection with a novel, unidentified mycobacterium in a man with the acquired immunodeficiency syndrome. N Engl J Med (1990) 2.54
Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J Clin Invest (1996) 2.49
The distribution of antigenic and nonantigenic compounds within draining lymph nodes. Lab Invest (1966) 2.49
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica. Cytokine (1993) 2.48
Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms. J Clin Invest (1986) 2.47
Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45
Morphological and immunochemical differences between keloid and hypertrophic scar. Am J Pathol (1994) 2.44
Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells. J Biol Chem (1995) 2.43
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. Eur Respir J (1994) 2.41
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism. Hum Mol Genet (1999) 2.32
Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc Natl Acad Sci U S A (2000) 2.32
Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport. J Cell Biol (1979) 2.29
Altered surfactant function and structure in SP-A gene targeted mice. Proc Natl Acad Sci U S A (1996) 2.29
The extrathymic T-cell development pathway. Immunol Today (1992) 2.27
Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Cell (1995) 2.25
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions. J Exp Med (1991) 2.24
Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science (1994) 2.24
Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol Rev (1989) 2.22
Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med (1999) 2.20
Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature (1992) 2.18
Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. J Biol Chem (1992) 2.18
cis-acting elements that confer lung epithelial cell expression of the CC10 gene. J Biol Chem (1992) 2.18
rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. Mol Cell Biol (1994) 2.12
Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung. J Immunol (2000) 2.12
FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am J Physiol Lung Cell Mol Physiol (2001) 2.12
Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest (1991) 2.11
"Contractile interstitial cells" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies. J Cell Biol (1974) 2.11
Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature (1977) 2.10
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem (1996) 2.03
Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity. J Clin Invest (1994) 1.96
Oxygen toxicity in mouse lung: pathways to cell death. Am J Respir Cell Mol Biol (1998) 1.94
Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection. Am J Respir Cell Mol Biol (1998) 1.92
Thymus-independent (B) cell proliferation in spleen cell cultures of mouse radiation chimeras stimulated by phytohemagglutinin or allogeneic cells. J Exp Med (1972) 1.90
Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas. Mod Pathol (1996) 1.90
An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J (1997) 1.90
Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice. Cancer Res (1992) 1.86
Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood. Am J Physiol Lung Cell Mol Physiol (2004) 1.84
Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases. Proc Natl Acad Sci U S A (1988) 1.82
Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest (1997) 1.81
Surfactant protein D enhances clearance of influenza A virus from the lung in vivo. J Immunol (2001) 1.79
Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice. J Exp Med (1994) 1.79
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur J Immunol (1991) 1.78
Surfactant protein-D regulates surfactant phospholipid homeostasis in vivo. J Biol Chem (1998) 1.77
Surfactant protein A-deficient mice are susceptible to group B streptococcal infection. J Immunol (1997) 1.77
Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. J Clin Invest (1999) 1.77