Published in Diabetologia on July 01, 1995
Mitochondrial genetics '98 is the bottleneck cracked? Am J Hum Genet (1998) 2.02
Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: support for a genetic bottleneck. Am J Hum Genet (1997) 1.56
Is Placental Mitochondrial Function a Regulator that Matches Fetal and Placental Growth to Maternal Nutrient Intake in the Mouse? PLoS One (2015) 1.40
Mitochondrial genetics. Br Med Bull (2013) 1.30
Multisystem manifestations of mitochondrial disorders. J Neurol (2009) 1.25
Transmission of mitochondrial DNA diseases and ways to prevent them. PLoS Genet (2010) 1.08
Mitochondria and diabetes mellitus: untangling a conflictive relationship? J Inherit Metab Dis (2009) 1.06
Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids. Genetics (2005) 1.00
Genetic Counselling for Maternally Inherited Mitochondrial Disorders. Mol Diagn Ther (2017) 0.92
Mitochondrial DNA disease and developmental implications for reproductive strategies. Mol Hum Reprod (2014) 0.90
Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release. Mol Aspects Med (2015) 0.77
Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature (1997) 7.33
Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med (1999) 6.94
Protective effect of breast feeding against infection. BMJ (1990) 5.88
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature (2000) 5.86
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nat Genet (1997) 4.77
Designing conditions for in vitro formation of amyloid protofilaments and fibrils. Proc Natl Acad Sci U S A (1999) 4.71
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature (2010) 4.52
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci U S A (1987) 4.19
A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat Genet (1998) 4.06
LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. Nat Genet (2000) 3.73
Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat Genet (2001) 3.50
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest (2000) 3.10
The perils of portliness: causes and consequences of visceral adiposity. Diabetes (2000) 2.96
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci U S A (2009) 2.95
Disease mapping models: an empirical evaluation. Disease Mapping Collaborative Group. Stat Med (2001) 2.88
Genetics of body-weight regulation. Nature (2000) 2.84
Change in obstetric practice in response to fear of litigation in the British Isles. Lancet (1991) 2.78
Confirmatory assay increases specificity of the chlamydiazyme test for Chlamydia trachomatis infection of the cervix. J Clin Microbiol (1990) 2.65
Linkage of type 2 diabetes to the glucokinase gene. Lancet (1992) 2.64
An activating mutation of AKT2 and human hypoglycemia. Science (2011) 2.60
Relation between early introduction of solid food to infants and their weight and illnesses during the first two years of life. BMJ (1993) 2.46
Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes (2001) 2.43
Declining T-cell immunity to influenza, 1977-82. Lancet (1983) 2.34
Quality of life measurements in patients with malignant disease: a review. J R Soc Med (1986) 2.28
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence? Diabetologia (2010) 2.21
Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes. Lancet (1987) 2.15
The use of various handwashing agents to decontaminate gloved hands. Br Dent J (1989) 2.03
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci U S A (2004) 2.03
Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection. Hepatology (1999) 2.02
Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. Int J Obes (Lond) (2009) 1.98
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest (1997) 1.95
The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology. Allergy (2007) 1.91
The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. Diabetologia (2009) 1.87
The evidence for beta blockers in heart failure. BMJ (1999) 1.84
Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy. J Med Genet (2002) 1.84
Partial leptin deficiency and human adiposity. Nature (2001) 1.83
Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals. Diabetologia (2009) 1.81
Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome. Clin Exp Allergy (2011) 1.81
Rapid reversal of hyperoxaluria in a rat model after probiotic administration of Oxalobacter formigenes. J Urol (2001) 1.74
The heart failure epidemic: exactly how big is it? Eur Heart J (2001) 1.73
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group. Pediatr Pulmonol (1998) 1.73
Genetic factors in human obesity. Obes Rev (2007) 1.72
Regulation of adipose cell number in man. Clin Sci (Lond) (1997) 1.72
Analysis of pace-maker and repolarization currents in frog atrial muscle. J Physiol (1976) 1.72
Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab (2006) 1.71
Effector functions of a monoclonal aglycosylated mouse IgG2a: binding and activation of complement component C1 and interaction with human monocyte Fc receptor. Mol Immunol (1985) 1.68
Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism. Lancet (1993) 1.65
Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology. Biochim Biophys Acta (2001) 1.63
Multivesicular exocytosis in rat pancreatic beta cells. Diabetologia (2011) 1.63
Oral androgens in the treatment of hypogonadal impotent men. J Urol (1994) 1.61
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis. J Mol Biol (2001) 1.57
Identification of the pace-maker current in frog atrium. J Physiol (1976) 1.56
Immune-mediated reactions to althesin (alphaxalone). Br J Anaesth (1976) 1.56
Evidence for gene-nutrient interaction at the PPARgamma locus. Diabetes (2001) 1.54
A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker. Diabetologia (2010) 1.53
Do facial averageness and symmetry signal health? Evol Hum Behav (2001) 1.52
Functional health status levels of primary care patients. JAMA (1983) 1.52
Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes (1997) 1.52
Changes in blood flow close to subcutaneous insulin injection sites in stable and brittle diabetics. Diabetes (1983) 1.51
Reactogenicity and immunogenicity of inactivated influenza A (H1N1) virus vaccine in unprimed children. Report to the Medical Research Council Committee on influenza and other respiratory virus vaccines. J Biol Stand (1980) 1.48
Triple H syndrome: a novel autoimmune endocrinopathy characterized by dysfunction of the hippocampus, hair follicle, and hypothalamic-pituitary adrenal axis. J Clin Endocrinol Metab (2000) 1.48
The emergence of oseltamivir-resistant pandemic influenza A (H1N1) 2009 virus amongst hospitalised immunocompromised patients in Scotland, November-December, 2009. Euro Surveill (2010) 1.46
Randomized clinical trial of fluid and salt restriction compared with a controlled liberal regimen in elective gastrointestinal surgery. Br J Surg (2013) 1.46
Expression of the thermogenic nuclear hormone receptor coactivator PGC-1alpha is reduced in the adipose tissue of morbidly obese subjects. Int J Obes Relat Metab Disord (2004) 1.46
Clinical studies of monovalent inactivated whole virus and subunit A/USSR/77 (H1N1) vaccine: serological responses and clinical reactions. J Biol Stand (1979) 1.45
A gene for congenital generalized lipodystrophy maps to human chromosome 9q34. J Clin Endocrinol Metab (1999) 1.44
Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes (1998) 1.43
Evaluation of Syva's enzyme immunoassay for the detection of Chlamydia trachomatis in urogenital specimens. Diagn Microbiol Infect Dis (1993) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40
Is the defect in pro-hormone processing in Type 2 diabetes mellitus restricted to the beta cell? Diabet Med (2001) 1.39
Type II diabetes of early onset: a distinct clinical and genetic syndrome? Br Med J (Clin Res Ed) (1987) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Severe insulin resistance, diabetes mellitus, hypertriglyceridemia, and pseudoacromegaly. J Clin Endocrinol Metab (1996) 1.39
Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro. Diabetologia (2005) 1.38
Attractiveness of facial averageness and symmetry in non-western cultures: in search of biologically based standards of beauty. Perception (2001) 1.37
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation. Mol Endocrinol (2001) 1.36
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Reactogenicity and immunogenicity of whole and ether-Tween-split influenza A virus vaccines in volunteers. J Infect Dis (1978) 1.33
Molecular characterization of the alpha-glucosidase gene (malA) from the hyperthermophilic archaeon Sulfolobus solfataricus. J Bacteriol (1998) 1.33
Monogenic human obesity syndromes. Recent Prog Horm Res (2004) 1.33
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Abnormal RNA processing associated with a novel tRNA mutation in mitochondrial DNA. A potential disease mechanism. J Biol Chem (1993) 1.31
Precision top-quark mass measurement at CDF. Phys Rev Lett (2012) 1.30
WNT10B mutations in human obesity. Diabetologia (2006) 1.29
Spectrum of spontaneous frameshift mutations. Sequences of bacteriophage T4 rII gene frameshifts. J Mol Biol (1986) 1.28
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Formation of amyloid fibrils by peptides derived from the bacterial cold shock protein CspB. Protein Sci (1999) 1.27
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes. Diabetologia (2006) 1.27
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet (2001) 1.26
Preparation of synthetic human islet amyloid polypeptide (IAPP) in a stable conformation to enable study of conversion to amyloid-like fibrils. FEBS Lett (2000) 1.25
Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes. Diabetes (1998) 1.25
The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation. Cell Death Differ (2009) 1.24
Inhibition of Neisseria gonorrhoeae by normal human saliva. Br J Vener Dis (1979) 1.23
Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance. J Clin Endocrinol Metab (1993) 1.22
Measurement of the cross section for prompt isolated diphoton production using the full CDF run II data sample. Phys Rev Lett (2013) 1.22