| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Cloning and characterization of a mammalian proton-coupled metal-ion transporter.
|
Nature
|
1997
|
9.98
|
|
2
|
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents.
|
Gastroenterology
|
1996
|
1.28
|
|
3
|
Wilson's disease, presenting as chronic active hepatitis.
|
Gastroenterology
|
1978
|
1.26
|
|
4
|
Increased expression of human ribosomal phosphoprotein P0 messenger RNA in hepatocellular carcinoma and colon carcinoma.
|
Cancer Res
|
1992
|
1.13
|
|
5
|
Prolonged survival in three brothers with severe type 2 Crigler-Najjar syndrome. Ultrastructural and metabolic studies.
|
Gastroenterology
|
1975
|
1.04
|
|
6
|
Role of the hepatocyte microtubular system in the excretion of bile salts and biliary lipid: implications for intracellular vesicular transport.
|
J Lipid Res
|
1988
|
1.02
|
|
7
|
Enhanced activity of the free radical producing enzyme xanthine oxidase in hypoxic rat liver. Regulation and pathophysiologic significance.
|
J Clin Invest
|
1991
|
1.02
|
|
8
|
Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis.
|
Hepatology
|
1995
|
1.01
|
|
9
|
Subcellular distribution and regulation of hepatic bilirubin UDP-glucuronyltransferase.
|
J Biol Chem
|
1984
|
1.00
|
|
10
|
Membrane lipid composition and vesicle size modulate bilirubin intermembrane transfer. Evidence for membrane-directed trafficking of bilirubin in the hepatocyte.
|
J Biol Chem
|
1994
|
0.99
|
|
11
|
Hepatic microsomal glucuronidation of bilirubin is modulated by the lipid microenvironment of membrane-bound substrate.
|
J Biol Chem
|
1986
|
0.97
|
|
12
|
Kinetics of bilirubin transfer between serum albumin and membrane vesicles. Insight into the mechanism of organic anion delivery to the hepatocyte plasma membrane.
|
J Biol Chem
|
1995
|
0.97
|
|
13
|
Sex differences in hepatic uptake of long chain fatty acids in single-pass perfused rat liver.
|
J Lipid Res
|
1981
|
0.94
|
|
14
|
Effect of dietary composition on the unconjugated hyperbilirubinaemia of Gilbert's syndrome.
|
Gut
|
1976
|
0.94
|
|
15
|
Mechanism of the spontaneous transfer of unconjugated bilirubin between small unilamellar phosphatidylcholine vesicles.
|
Biochemistry
|
1992
|
0.94
|
|
16
|
Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium-potassium-adenosinetriphosphatase activity.
|
Am J Physiol
|
1994
|
0.93
|
|
17
|
Fulminant Wilson's disease with haemolysis and renal failure: copper studies and assessment of dialysis regimens.
|
Br Med J
|
1977
|
0.92
|
|
18
|
The role of albumin in hepatic uptake processes.
|
Prog Liver Dis
|
1982
|
0.91
|
|
19
|
Hepatic microsomal glucuronidation of bilirubin in unilamellar liposomal membranes. Implications for intracellular transport of lipophilic substrates.
|
J Biol Chem
|
1984
|
0.91
|
|
20
|
Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin. Implications for the intracellular transport of nonsubstrate ligands in hepatocytes.
|
J Clin Invest
|
1995
|
0.91
|
|
21
|
Oxygen consumption by rat liver: effects of taurocholate and sulfobromophthalein transport, glucagon, and cation substitution.
|
Am J Physiol
|
1983
|
0.91
|
|
22
|
Hepatic uptake of albumin-bound substances: albumin receptor concept.
|
Am J Physiol
|
1983
|
0.90
|
|
23
|
A membrane transporter mediates access of uridine 5'-diphosphoglucuronic acid from the cytosol into the endoplasmic reticulum of rat hepatocytes: implications for glucuronidation reactions.
|
Biochim Biophys Acta
|
1988
|
0.88
|
|
24
|
A radiometric assay of copper binding in biological fluids and its application to alimentary secretions in normal subjects and Wilson's disease.
|
Clin Chim Acta
|
1971
|
0.88
|
|
25
|
Hepatic microsomal bilirubin UDP-glucuronosyltransferase. The kinetics of bilirubin mono- and diglucuronide synthesis.
|
J Biol Chem
|
1992
|
0.88
|
|
26
|
Evidence for a low Km transporter for non-transferrin-bound iron in isolated rat hepatocytes.
|
Am J Physiol
|
1995
|
0.87
|
|
27
|
Performance characteristics and results of a large-scale screening program for viral hepatitis and risk factors associated with exposure to viral hepatitis B and C: results of the National Hepatitis Screening Survey. National Hepatitis Surveillance Group.
|
Hepatology
|
1996
|
0.86
|
|
28
|
The role of conjugation reactions in enhancing biliary secretion of bile acids.
|
Biochem J
|
1983
|
0.85
|
|
29
|
Bilirubin update: formation, transport, and metabolism.
|
Prog Liver Dis
|
1982
|
0.84
|
|
30
|
Synthesis of bile acid monosulphates by the isolated perfused rat kidney.
|
Biochem J
|
1976
|
0.84
|
|
31
|
Deconjugation of bilirubin-IX alpha glucuronides: a physiologic role of hepatic microsomal beta-glucuronidase.
|
J Biol Chem
|
1993
|
0.84
|
|
32
|
Serum antioxidant activity in normal and abnormal subjects.
|
Ann Clin Biochem
|
1979
|
0.83
|
|
33
|
Hepatocyte cotransport of taurocholate and bilirubin glucuronides: role of microtubules.
|
Am J Physiol
|
1988
|
0.83
|
|
34
|
The role of tubular reabsorption in the renal excretion of bile acids.
|
Biochem J
|
1977
|
0.83
|
|
35
|
Red cell aplasia following prolonged D-penicillamine therapy.
|
J Clin Pathol
|
1976
|
0.83
|
|
36
|
Studies on the nature and excretion of biliary copper in man.
|
Clin Sci
|
1973
|
0.83
|
|
37
|
Ryanodine-induced calcium release from hepatic microsomes and permeabilized hepatocytes.
|
Am J Physiol
|
1995
|
0.82
|
|
38
|
Heme enhances hexobarbital metabolism in perfused rat liver after drug-mediated destruction of cytochrome P-450.
|
J Pharmacol Exp Ther
|
1981
|
0.82
|
|
39
|
Current concepts of bilirubin metabolism and hereditary hyperbilirubinemia.
|
Prog Liver Dis
|
1979
|
0.82
|
|
40
|
Gilbert's syndrome.
|
Baillieres Clin Gastroenterol
|
1989
|
0.81
|
|
41
|
Efflux of bilirubin into plasma following hepatic degradation of exogenous heme.
|
Proc Soc Exp Biol Med
|
1980
|
0.81
|
|
42
|
Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles.
|
Gastroenterology
|
1995
|
0.81
|
|
43
|
Transcellular transport of organic anions in hepatocytes: still a long way to go.
|
Hepatology
|
1991
|
0.81
|
|
44
|
Reduced oxidase activity in the caeruloplasmin of two families with Wilson's disease.
|
J Clin Pathol
|
1977
|
0.81
|
|
45
|
Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs.
|
Biochim Biophys Acta
|
1994
|
0.80
|
|
46
|
Visceral cryptococcosis without central nervous system or pulmonary involvement: presentation as hepatitis.
|
Med J Aust
|
1972
|
0.80
|
|
47
|
The influence of diet on unconjugated hyperbilirubinaemia in the Gunn rat.
|
Clin Sci Mol Med
|
1975
|
0.80
|
|
48
|
Taurocholate induces pericanalicular localization of C6-NBD-ceramide in isolated hepatocyte couplets.
|
Am J Physiol
|
1991
|
0.80
|
|
49
|
Hepatocellular expression of glucose-6-phosphatase is unaltered during hepatic regeneration.
|
Am J Physiol
|
1998
|
0.79
|
|
50
|
Copper content of human alimentary secretions.
|
Clin Biochem
|
1971
|
0.79
|
|
51
|
Excretion of conjugated bilirubin in the isolated perfused rat kidney.
|
Clin Sci Mol Med
|
1978
|
0.79
|
|
52
|
Ultrastructural changes in the isolated rat kidney induced by conjugated bilirubin and bile acids.
|
Br J Exp Pathol
|
1976
|
0.78
|
|
53
|
Cirrhosis as a consequence of graft-versus-host disease.
|
Gastroenterology
|
1987
|
0.78
|
|
54
|
Mechanisms and significance of fasting and dietary hyperbilirubinemia.
|
Semin Liver Dis
|
1983
|
0.78
|
|
55
|
Scatchard plots.
|
Science
|
1982
|
0.78
|
|
56
|
Membrane-membrane interactions associated with rapid transfer of liposomal bilirubin to microsomal UDP-glucuronyltransferase. Relevance for hepatocellular transport and biotransformation of hydrophobic substrates.
|
Biochem J
|
1987
|
0.78
|
|
57
|
Regulation of hepatocyte bile salt transporters during hepatic regeneration.
|
Am J Physiol
|
1997
|
0.78
|
|
58
|
Crigler-Najjar Type 1 syndrome: absence of hepatic bilirubin UDP-glucuronyl transferase activity and therapeutic responses to light.
|
Aust N Z J Med
|
1982
|
0.77
|
|
59
|
Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum.
|
Biochim Biophys Acta
|
1996
|
0.77
|
|
60
|
Treatment of Wilson's disease: in D-penicillamine we trust--what about zinc?
|
Hepatology
|
1987
|
0.77
|
|
61
|
Hypoxic liver injury and the ameliorating effects of fructose: the "glucose paradox" revisited.
|
Am J Physiol
|
1992
|
0.77
|
|
62
|
Diagnosis of hemochromatosis.
|
Gastroenterology
|
1983
|
0.77
|
|
63
|
Advances in hepatic transport: molecular mechanisms, genetic disorders, and treatment. A summary of the 1998 AASLD single topic conference.
|
Hepatology
|
1998
|
0.77
|
|
64
|
Liver cancer.
|
CA Cancer J Clin
|
1989
|
0.77
|
|
65
|
Regulation of bilirubin glucuronide synthesis in primate (Macaca fascicularis) liver. Kinetic analysis of microsomal bilirubin uridine diphosphate glucuronyltransferase.
|
Gastroenterology
|
1986
|
0.76
|
|
66
|
Primary biliary cirrhosis: new therapeutic directions.
|
Scand J Gastroenterol Suppl
|
1992
|
0.76
|
|
67
|
Binding of copper by human alimentary secretions.
|
Am J Clin Nutr
|
1971
|
0.76
|
|
68
|
Incorporation of haemoglobin haem into the rat hepatic haemoproteins tryptophan pyrrolase and cytochrome P-450.
|
Biochem J
|
1986
|
0.75
|
|
69
|
Crigler-Najjar disease type I: therapeutic approaches to genetic liver diseases into the next century.
|
Gastroenterology
|
1997
|
0.75
|
|
70
|
Hepatic disposition and biliary excretion of bilirubin and bilirubin glucuronides in intact rats. Differential processing of pigments derived from intra- and extrahepatic sources.
|
J Clin Invest
|
1987
|
0.75
|
|
71
|
Formation, hepatic metabolism, and transport of bile pigments: a status report.
|
Semin Liver Dis
|
1988
|
0.75
|
|
72
|
Jaundice following oral surgery: Gilberts syndrome.
|
Br J Oral Surg
|
1975
|
0.75
|
|
73
|
Interaction of uridine 5'-diphosphoglucuronic acid with microsomal UDP-glucuronosyltransferase in primate liver: the facilitating role of uridine 5'-diphospho-N-acetylglucosamine.
|
Biochim Biophys Acta
|
1988
|
0.75
|
|
74
|
Intracellular transport of small hydrophobic compounds by the hepatocyte.
|
Semin Liver Dis
|
1996
|
0.75
|
|
75
|
Evaluation of University of Wisconsin cold-storage solution in warm hypoxic perfusion of rat liver: the addition of fructose reduces injury.
|
Gastroenterology
|
1993
|
0.75
|
|
76
|
The role of dietary lipid in the regulation of unconjugated hyperbilirubinaemia in Gunn rats.
|
Clin Sci (Lond)
|
1979
|
0.75
|
|
77
|
Iron overload diseases.
|
Ala J Med Sci
|
1988
|
0.75
|
|
78
|
Effects of human alimentary secretions on 64 Cu diffusion in an in vitro system.
|
Aust J Biol Sci
|
1971
|
0.75
|
|
79
|
Genetic hemochromatosis: pathogenesis, diagnosis, and therapy.
|
Dig Dis
|
1997
|
0.75
|
|
80
|
The effect of carbenoxolone sodium on the plasma 11 hydroxycorticoid levels in chronic gastric ulceration.
|
Aust N Z J Med
|
1975
|
0.75
|
|
81
|
Heptolenticular degeneration (Wilson's disease) in an Australian Aboriginal.
|
Med J Aust
|
1970
|
0.75
|
|
82
|
The role of human bile in the absorption of endogenous and exogenous radiocopper.
|
Gut
|
1969
|
0.75
|
|
83
|
Mechanisms of formation, hepatic transport, and metabolism of bile pigments.
|
Prog Clin Biol Res
|
1984
|
0.75
|
|
84
|
Physical and biological properties of fluorescent dansylated bile salt derivatives: the role of steroid ring hydroxylation.
|
Biochim Biophys Acta
|
1991
|
0.75
|
|
85
|
Hepatic regeneration is associated with preservation of microsomal glucuronidation.
|
Hepatology
|
1996
|
0.75
|
|
86
|
Chronic polymyositis: complete heart block and cryoglobulinaemia.
|
Med J Aust
|
1974
|
0.75
|
|
87
|
Bilirubin metabolism and congenital jaundice.
|
Hosp Pract (Off Ed)
|
1985
|
0.75
|
|
88
|
Mechanistic and molecular aspects of hepatic bilirubin glucuronidation.
|
Prog Liver Dis
|
1990
|
0.75
|
|
89
|
Hereditary disorders of bilirubin metabolism.
|
Acta Hepatogastroenterol (Stuttg)
|
1974
|
0.75
|
|
90
|
Proceedings: Prolonged survival in the Crigler-Najjar syndrome: ultrastructural and dietary studies.
|
Gut
|
1974
|
0.75
|
|
91
|
The demonstration of copper-complex formation by endogenous alimentary chelates.
|
Gut
|
1969
|
0.75
|