Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarily on hepatitis C virus RNA level.

PubWeight™: 1.47‹?› | Rank: Top 5%

🔗 View Article (PMID 7590646)

Published in Hepatology on November 01, 1995

Authors

G Yamada1, M Takatani, F Kishi, M Takahashi, T Doi, T Tsuji, S Shin, M Tanno, M S Urdea, J A Kolberg

Author Affiliations

1: First Department of Internal Medicine, Okayama University Medical School, Japan.

Articles citing this

A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml. Nucleic Acids Res (1997) 4.40

Improved version 2.0 qualitative and quantitative AMPLICOR reverse transcription-PCR tests for hepatitis C virus RNA: calibration to international units, enhanced genotype reactivity, and performance characteristics. J Clin Microbiol (2000) 2.70

Accurate quantification of hepatitis C virus (HCV) RNA from all HCV genotypes by using branched-DNA technology. J Clin Microbiol (1996) 2.26

Genotype dependence of hepatitis C virus load measurement in commercially available quantitative assays. J Clin Microbiol (1999) 1.68

Interferon-alpha 2b combined with daily ketoprofen administration improves virological response in chronic hepatitis C: a prospective and randomised trial. Gut (2000) 1.45

Comparison of plasma virus loads among individuals infected with hepatitis C virus (HCV) genotypes 1, 2, and 3 by quantiplex HCV RNA assay versions 1 and 2, Roche Monitor assay, and an in-house limiting dilution method. J Clin Microbiol (1997) 1.43

Quantification of hepatitis C virus in human liver and serum samples by using LightCycler reverse transcriptase PCR. J Clin Microbiol (2002) 1.14

Genetic variation of hepatitis C virus in a cohort of injection heroin users in Wuhan, China. Virus Res (2008) 1.02

Performance characteristics of the COBAS Amplicor Hepatitis C Virus (HCV) Monitor, Version 2.0, International Unit assay and the National Genetics Institute HCV Superquant assay. J Clin Microbiol (2002) 0.97

Rapid normalization of alanine aminotransferase predicts viral response during combined peginterferon and ribavirin treatment in chronic hepatitis C patients. Korean J Hepatol (2012) 0.95

Correlation of viral loads with HCV genotypes: higher levels of virus were revealed among blood donors infected with 6a strains. PLoS One (2012) 0.87

Combination thymosin alpha 1 and lymphoblastoid interferon treatment in chronic hepatitis C. Gut (1996) 0.85

Assessment of spontaneous fluctuations of viral load in untreated patients with chronic hepatitis C by two standardized quantitation methods: branched DNA and Amplicor Monitor. J Clin Microbiol (1998) 0.82

Hepatitis C virus quantitation: optimization of strategies for detecting low-level viremia. J Clin Microbiol (2000) 0.82

The Effect Of Long Term and High Dose Interferon Treatment In Chronic Hepatitis C. Pathol Oncol Res (1996) 0.77

An analysis of risk factors for developing Hepatocellular carcinoma in a group of Hepatitis C patients with stage 3 fibrosis following interferon therapy. Cancer Inform (2008) 0.77

Endogenous interferon-alpha concentration and outcome of interferon treatment in patients with chronic hepatitis C. Dig Dis Sci (1997) 0.77

Study of the effect of antiviral therapy on homocysteinemia in hepatitis C virus- infected patients. BMC Gastroenterol (2012) 0.75

Viral and host factors in determining response of relapsers with chronic hepatitis C to retreatment with interferon. Dig Dis Sci (1999) 0.75

Articles by these authors

(truncated to the top 100)

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun (1999) 14.25

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85

Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet (1988) 8.76

Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region. J Gen Virol (1993) 8.07

Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1. DNA Res (1999) 7.39

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end. Proc Natl Acad Sci U S A (1991) 7.13

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation (2000) 6.96

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene (2008) 6.82

Development of a self-inactivating lentivirus vector. J Virol (1998) 6.60

Diversity of Chlamydia trachomatis major outer membrane protein genes. J Bacteriol (1987) 6.16

The dilemma of MDR-TB in the global era. Int J Tuberc Lung Dis (1998) 5.77

A single intravenous infusion of gamma globulin as compared with four infusions in the treatment of acute Kawasaki syndrome. N Engl J Med (1991) 5.76

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature (1997) 5.55

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation (2000) 5.36

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18

Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's. Science (1989) 5.08

Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas. J Magn Reson Imaging (1999) 4.94

Prediction of acute left main coronary artery obstruction by 12-lead electrocardiography. ST segment elevation in lead aVR with less ST segment elevation in lead V(1). J Am Coll Cardiol (2001) 4.81

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature (1986) 4.81

Comparison of MB-Check, BACTEC, and egg-based media for recovery of mycobacteria. J Clin Microbiol (1992) 4.55

Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet (1993) 4.51

The treatment of Kawasaki syndrome with intravenous gamma globulin. N Engl J Med (1986) 4.49

Homology requirements for recombination in Escherichia coli. Proc Natl Acad Sci U S A (1985) 4.46

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42

A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml. Nucleic Acids Res (1997) 4.40

Bell palsy and herpes simplex virus: identification of viral DNA in endoneurial fluid and muscle. Ann Intern Med (1996) 4.27

Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med (1998) 4.17

Initial and 6-month results of biodegradable poly-l-lactic acid coronary stents in humans. Circulation (2000) 4.05

Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell (1993) 4.04

Detection of Mycobacterium tuberculosis in clinical specimens by polymerase chain reaction and Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test. J Clin Microbiol (1993) 4.04

Sub-piconewton force fluctuations of actomyosin in vitro. Nature (1991) 3.89

Activation of a novel human transforming gene, ret, by DNA rearrangement. Cell (1985) 3.86

A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization. Cell (1989) 3.70

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun (1987) 3.46

Immunological nonidentity of heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli. Infect Immun (1981) 3.46

Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet (2000) 3.42

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A (1997) 3.40

Timely diagnosis of MDR-TB under program conditions: is rapid drug susceptibility testing sufficient? Int J Tuberc Lung Dis (2006) 3.34

Live vaccine used to prevent the spread of varicella in children in hospital. Lancet (1974) 3.24

The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli. Infect Immun (2000) 3.20

Isolation of the yeast calmodulin gene: calmodulin is an essential protein. Cell (1986) 3.17

Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization. Nucleic Acids Res (1986) 3.11

Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med (1996) 3.02

Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7. DNA Res (2001) 2.99

Use of unpurified synthetic deoxynucleotide primers for rapid dideoxynucleotide chain termination sequencing. DNA (1984) 2.96

Characterization of a multicomponent receptor for GDNF. Nature (1996) 2.92

Herpesviridae. Definition, provisional nomenclature, and taxonomy. The Herpesvirus Study Group, the International Committee on Taxonomy of Viruses. Intervirology (1981) 2.92

Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle. J Cell Biol (1995) 2.88

Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury. Proc Natl Acad Sci U S A (1999) 2.84

Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol (1992) 2.83

An Epstein-Barr virus-producer line Akata: establishment of the cell line and analysis of viral DNA. Virus Genes (1991) 2.77

The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. Science (1993) 2.77

Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1984) 2.74

Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization. Science (1985) 2.72

Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Nat Immunol (2000) 2.66

Application of branched DNA signal amplification to monitor human immunodeficiency virus type 1 burden in human plasma. J Infect Dis (1994) 2.60

An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res (2000) 2.59

Seroepidemiology of human herpesvirus 6 infection in normal children and adults. J Clin Microbiol (1989) 2.58

At least five related, but distinct, hepatitis C viral genotypes exist. Proc Natl Acad Sci U S A (1992) 2.56

Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions. J Gen Virol (1994) 2.53

The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur J Immunol (1992) 2.52

Kinetic and equilibrium characterization of the Tet repressor-tetracycline complex by fluorescence measurements. Evidence for divalent metal ion requirement and energy transfer. J Mol Biol (1986) 2.52

Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49

ret transforming gene encodes a fusion protein homologous to tyrosine kinases. Mol Cell Biol (1987) 2.48

Mutations in the rpoB gene of rifampin-resistant Mycobacterium tuberculosis strains isolated mostly in Asian countries and their rapid detection by line probe assay. J Clin Microbiol (1999) 2.46

Fractures of the coracoid process. J Bone Joint Surg Br (1997) 2.45

Use of minilaparotomy in the treatment of colonic cancer. Br J Surg (2001) 2.41

Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis. Tuber Lung Dis (1997) 2.34

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res (1998) 2.32

Diagnosis and therapy of Kawasaki disease in children. Circulation (1993) 2.32

The inhomogeneous structure of water at ambient conditions. Proc Natl Acad Sci U S A (2009) 2.31

A simple procedure for mass spectrometric microanalysis of 15N in particulate organic matter with special reference to 15N-tracer experiments. Anal Biochem (1977) 2.31

Synthesis and antitumor activity of benzimidazolyl-1,3,5-triazine and benzimidazolylpyrimidine derivatives. Chem Pharm Bull (Tokyo) (2000) 2.30

A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structure. J Exp Med (1993) 2.29

Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus. J Virol (1989) 2.28

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. Nature (1986) 2.28

Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci U S A (1999) 2.27

Isolation of human cDNA clones of myb-related genes, A-myb and B-myb. Nucleic Acids Res (1988) 2.26

Posttherapeutic intraaxial brain tumor: the value of perfusion-sensitive contrast-enhanced MR imaging for differentiating tumor recurrence from nonneoplastic contrast-enhancing tissue. AJNR Am J Neuroradiol (2000) 2.24

Requirements for the solubilization of immune aggregates by complement. The role of the classical pathway. J Clin Invest (1978) 2.24

LexA protein is a repressor of the colicin E1 gene. J Biol Chem (1983) 2.24

Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase. Biochemistry (1996) 2.24

Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle. Proc Natl Acad Sci U S A (1987) 2.22

Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature (1997) 2.20

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat Genet (1997) 2.20

Subcellular location of superoxide dismutase in spinach leaves and preparation and properties of crystalline spinach superoxide dismutase. Eur J Biochem (1973) 2.19

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7. J Biol Chem (2001) 2.19

Solubilization of antigen-antibody complexes: a new function of complement as a regulator of immune reactions. Prog Allergy (1980) 2.19

Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA. Nucleic Acids Res (2000) 2.16

Treatment of hepatocellular carcinoma: value of percutaneous microwave coagulation. AJR Am J Roentgenol (1995) 2.13

Structural requirements of tetracycline-Tet repressor interaction: determination of equilibrium binding constants for tetracycline analogs with the Tet repressor. Antimicrob Agents Chemother (1991) 2.12

Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol (2001) 2.12

Superoxide dismutases from a blue-green alga, Plectonema boryanum. J Biol Chem (1975) 2.11

Mass spectrometry proves under-O-glycosylation of glomerular IgA1 in IgA nephropathy. Kidney Int (2001) 2.10

Identification of a syntaxin-binding site on N-type calcium channels. Neuron (1994) 2.09

Novel combretastatin analogues effective against murine solid tumors: design and structure-activity relationships. J Med Chem (1998) 2.09

Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J Clin Invest (2001) 2.07

Construction and evaluation of an instrument for the automated synthesis of oligodeoxyribonucleotides. DNA (1984) 2.07

Patterns of recurrence after initial treatment in patients with small hepatocellular carcinoma. Hepatology (1997) 2.07