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Clinical pharmacology in the National Health Service. J R Soc Med (1978) 2.54

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Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet (1994) 6.89

Review of company postmarketing surveillance studies. BMJ (1992) 6.21

Attitudinal survey of adverse drug reaction reporting by medical practitioners in the United Kingdom. Br J Clin Pharmacol (1995) 4.72

Monitoring adverse reactions to drugs. Br Med J (1977) 4.41

A double-blind placebo-controlled study of buspirone in diazepam withdrawal in chronic benzodiazepine users. Br J Psychiatry (1990) 3.74

Extrapyramidal reactions with metoclopramide. Br Med J (Clin Res Ed) (1985) 2.97

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Clinical pharmacology in the National Health Service. J R Soc Med (1978) 2.54

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Prescribing at the interface between hospitals and general practitioners. BMJ (1992) 2.47

The role of the pharmaceutical industry in postgraduate medical education. Br J Clin Pharmacol (1977) 2.45

Clinical pharmacology clinics in general practice. Br Med J (1977) 2.28

Doctors and the drug makers. Lancet (1984) 2.09

Extending the role of the community pharmacist. BMJ (1991) 2.05

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Factors affecting warfarin requirements. A prospective population study. Eur J Clin Pharmacol (1979) 1.95

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Psoriasis and cancer. Br Med J (1979) 1.71

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Drug information centres: a clinical pharmacologist's view. Proc R Soc Med (1977) 1.66

Pharmacokinetics and clinical toxicity of quinine overdosage: lack of efficacy of techniques intended to enhance elimination. Q J Med (1985) 1.65

Predicting patients' warfarin requirements. Lancet (1977) 1.61

Postmarketing surveillance of adverse reactions to drugs. Br Med J (Clin Res Ed) (1984) 1.57

Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme. Br Med J (Clin Res Ed) (1987) 1.46

Low prevalence of hepatitis B in mental handicap hospital. Lancet (1989) 1.45

Hospital prescribing and usage of hypnotics and anxiolytics. Br J Clin Pharmacol (1991) 1.44

Geographical differences in adverse drug reaction reporting rates in the Northern Region. Br J Clin Pharmacol (1991) 1.43

Spontaneous periodic hypothermia: diencephalic epilepsy. Br Med J (1973) 1.39

Extrapyramidal reactions to prochlorperazine and haloperidol in the United Kingdom. Q J Med (1986) 1.39

Pharmacokinetics and pharmacodynamics of warfarin at steady state. Br J Clin Pharmacol (1979) 1.36

Which drug for the adult epileptic patient: phenytoin or valproate? Br Med J (Clin Res Ed) (1985) 1.36

Clinical pharmacology. Adverse reactions to drugs. Br Med J (Clin Res Ed) (1981) 1.35

A method for obtaining saliva samples from infants and young children. Br J Clin Pharmacol (1978) 1.32

Accuracy of hepatic adverse drug reaction reporting in one English health region. BMJ (1999) 1.31

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Prazosin, pharmacokinetics and concentration effect. Eur J Clin Pharmacol (1979) 1.26

The effects of salicylate on temperature regulation in the rabbit. J Physiol (1970) 1.24

The activity of aryl hydrocarbon hydroxylase in adult human skin. Br J Clin Pharmacol (1979) 1.22

Prediction of drug oxidation rates in man: lack of correlation with serum gamma-glutamyl transpeptidase and urinary excretion of D-glucaric acid and 6 beta-hydroxycortisol. Eur J Clin Pharmacol (1974) 1.22

Serum anticonvulsant concentrations and the risk of drug induced skin eruptions. J Neurol Neurosurg Psychiatry (1984) 1.22

The association of age and frailty with paracetamol conjugation in man. Age Ageing (1990) 1.22

Distribution and elimination kinetics of carbamazepine in man. Eur J Clin Pharmacol (1975) 1.20

Efficacy and pharmacokinetics of aspirin in post-operative dental pain. Br J Clin Pharmacol (1982) 1.18

Who are the frail elderly? Q J Med (1988) 1.17

Benzodiazepines. Br Med J (1977) 1.15

Family study of antipyrine clearance. Br Med J (Clin Res Ed) (1982) 1.15

Pharmacokinetics of pancuronium in patients with normal and impaired renal function. Br J Anaesth (1976) 1.15

Decreased epidermal aryl hydrocarbon hydroxylase and localized pustular psoriasis. Br J Dermatol (1980) 1.14

Transferable pyrogen in human experimental fever. Clin Sci (1971) 1.13

Pharmacokinetics of parenteral paracetamol and its analgesic effects in post-operative dental pain. Eur J Clin Pharmacol (1981) 1.12

Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. Lancet (1981) 1.11

Aryl hydrocarbon hydroxylase activity and psoriasis. Biochem Pharmacol (1983) 1.11

The effects of astemizole on histamine-induced weal and flare. Eur J Clin Pharmacol (1983) 1.10

Hepatic drug acetylation and oxidation: effects of aging in man. Br Med J (1977) 1.09

Acute thermoregulatory and cardiovascular effects of 6-hydroxydopamine administered centrally in rabbits and cats. Br J Pharmacol (1972) 1.09

A comparison of phenytoin and valproate in previously untreated adult epileptic patients. J Neurol Neurosurg Psychiatry (1982) 1.09

Predicting the dose of warfarin for therapeutic anticoagulation. Thromb Haemost (1982) 1.09

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The effect of adrenaline in lignocaine anaesthetic solutions on plasma potassium in healthy volunteers. Eur J Clin Pharmacol (1987) 1.03

Influence of the duration of experimental fever on salicylate antipyresis in the rabbit. Br J Pharmacol (1971) 1.03

Plasma concentrations of sodium valproate: their clinical value. Ann Neurol (1983) 1.02

Using the Adverse Reactions Register to study the effects of age and sex on adverse drug reactions. Stat Med (1988) 1.01

Plasma aspirin esterase: the influence of old age and frailty. Age Ageing (1989) 1.01

The effects of intradermal bradykinin are potentiated by angiotensin converting enzyme inhibitors in hypertensive patients. Br J Clin Pharmacol (1989) 1.00

Steady-state plasma concentrations of alprenolol in man. Eur J Clin Pharmacol (1974) 1.00

Hypothalamic endogenous noradrenaline and thermoregulation in the cat and rabbit. J Physiol (1972) 0.99

Plasma concentration of alpha-methyldopa and sulphate conjugate after oral administration of methyldopa and intravenous administration of methyldopa and methyldopa hydrochloride ethyl ester. Eur J Clin Pharmacol (1975) 0.99

The effect of age on the pharmacokinetics of diazepam. Clin Sci (Lond) (1980) 0.99

Antipyrine clearance in psoriasis. Br Med J (Clin Res Ed) (1981) 0.99

Labetalol, a cross-over double blind controlled trial. Eur J Clin Pharmacol (1978) 0.96

Aspirin metabolism and efficacy in postoperative dental pain. Br J Clin Pharmacol (1984) 0.96

Determinants of plasma alpha 1-acid glycoprotein (AAG) concentrations in health. Br J Clin Pharmacol (1985) 0.96

The effect of alcoholic cirrhosis on the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin in human liver. Eur J Clin Pharmacol (1984) 0.94

Extrapyramidal reactions to metoclopramide and prochlorperazine. Q J Med (1989) 0.94

The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver. Br J Clin Pharmacol (1983) 0.94

Review of yellow cards (1986): report to the Committee on the Safety of Medicines. Br J Clin Pharmacol (1988) 0.93

Spontaneous reporting of adverse drug reactions. Q J Med (1986) 0.92

Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. II. Relationship to its effect on blood pressure and plasma renin activity. Eur J Clin Pharmacol (1976) 0.92

Predicting warfarin requirements. Lancet (1979) 0.92

Adverse reactions to N-acetylcysteine. Hum Toxicol (1984) 0.92

Spironolactone--a weak enzyme inducer in man. J Pharm Pharmacol (1972) 0.92

Phenelzine: acetylator status and clinical response. Br J Clin Pharmacol (1979) 0.91

Anabolic steroids: the power and the glory? BMJ (1988) 0.91

A comparison of the effect of two different dental local anaesthetic solutions on plasma potassium concentration. Br Dent J (1987) 0.91

The biochemical and haemodynamic effects of adrenaline in lignocaine local anaesthetic solutions in patients having third molar surgery under general anaesthesia. Br J Oral Maxillofac Surg (1991) 0.90

Activity of esterases in plasma from Ghanaian and British subjects. Eur J Clin Pharmacol (1986) 0.90

The efficacy and pharmacokinetics of sodium salicylate in post-operative dental pain. Br J Clin Pharmacol (1984) 0.90

"Therapeutic" serum concentration of phenytoin: the influence of seizure type. J Neurol Neurosurg Psychiatry (1984) 0.89