J J Reynolds

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987 4.56
2 Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 1985 3.97
3 Comparison of human stromelysin and collagenase by cloning and sequence analysis. Biochem J 1986 3.31
4 Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts. J Exp Med 1974 2.36
5 Evidence that latent collagenases are enzyme-inhibitor complexes. Biochem J 1977 2.32
6 Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components. Biochem J 1983 2.17
7 Purification of rabbit bone inhibitor of collagenase. Biochem J 1981 2.12
8 Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase. Biochem J 1989 1.89
9 Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase. J Biol Chem 1985 1.86
10 Immunolocalization of tissue inhibitor of metalloproteinases (TIMP) in human cells. Characterization and use of a specific antiserum. J Cell Sci 1985 1.73
11 The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor. Biochem J 1983 1.72
12 Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens. Biochem J 1982 1.66
13 The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes. Biochem J 1980 1.64
14 Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin. Biochem J 1981 1.62
15 Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans. Biochem J 1978 1.60
16 The detection and characterisation of collagenase inhibitors from rabbit tissues in culture. Biochim Biophys Acta 1977 1.57
17 Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen. Biochim Biophys Acta 1985 1.56
18 Collagenase is a component of the specific granules of human neutrophil leucocytes. Biochem J 1977 1.55
19 An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases. Biochem J 1981 1.52
20 Characterization of a specific antiserum to rabbit stromelysin and demonstration of the synthesis of collagenase and stromelysin by stimulated rabbit articular chondrocytes. Coll Relat Res 1986 1.50
21 The role of plasminogen activators in the regulation of connective tissue metalloproteinases. Ann N Y Acad Sci 1992 1.48
22 Origin of plasma alpha2HS-glycoprotein and its accumulation in bone. Nature 1976 1.41
23 Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J Biol Chem 1995 1.41
24 Binding of gelatinases A and B to type-I collagen and other matrix components. Biochem J 1995 1.41
25 Cytochalasin B increases collagenase production by cells in vitro. Nature 1975 1.40
26 A new factor that may control collagen resorption. Lancet 1977 1.38
27 Pyrophosphate stimulation of calcium uptake into cultured embryonic bones. Fine structure of matrix vesicles and their role in calcification. Dev Biol 1973 1.37
28 Inhibition by calcitonin of bone resorption induced in vitro by vitamin A. Proc R Soc Lond B Biol Sci 1968 1.35
29 The origin of matrix metalloproteinases and their familial relationships. FEBS Lett 1991 1.34
30 Identification and partial characterization of an inhibitor of collagenase from rabbit bone. Biochem J 1977 1.34
31 Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3. Biochem J 1998 1.29
32 Rabbit bone collagenase inhibitor blocks the activity of other neutral metalloproteinases. Biochem Biophys Res Commun 1979 1.29
33 Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. Biochim Biophys Acta 1991 1.28
34 Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis. Ann Rheum Dis 1995 1.27
35 Binding of latent and high Mr active forms of stromelysin to collagen is mediated by the C-terminal domain. J Cell Sci 1991 1.26
36 The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1. Biochem J 1991 1.25
37 Purification and characterization of human 72-kDa gelatinase (type IV collagenase). Use of immunolocalisation to demonstrate the non-coordinate regulation of the 72-kDa and 95-kDa gelatinases by human fibroblasts. Biol Chem Hoppe Seyler 1991 1.24
38 Characterization of a specific antiserum for mammalian collagenase from several species: immunolocalization of collagenase in rabbit chondrocytes and uterus. J Cell Sci 1986 1.22
39 Metalloproteinases and tissue damage. Br J Rheumatol 1991 1.18
40 Mouse osteoblasts synthesize collagenase in response to bone resorbing agents. Biochim Biophys Acta 1984 1.13
41 Metalloproteinase inhibitors from bovine cartilage and body fluids. Eur J Biochem 1984 1.13
42 Pig interleukin 1 (catabolin) is a potent stimulator of bone resorption in vitro. Calcif Tissue Int 1985 1.13
43 Immunochemical studies with a specific antiserum to rabbit fibroblast collagenase. Biochem J 1975 1.11
44 Immunolocalization of metalloproteinases and their inhibitor in the rabbit growth plate. J Bone Joint Surg Am 1989 1.11
45 Inhibition of type I collagen film degradation by tumour cells using a specific antibody to collagenase and the specific tissue inhibitor of metalloproteinases (TIMP). Cell Biol Int Rep 1985 1.10
46 The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. J Cell Sci 1994 1.10
47 Purification and properties of a specific collagenase from rabbit synovial fibroblasts. Biochem J 1975 1.10
48 Gelatinase (type IV collagenase) immunolocalization in cells and tissues: use of an antiserum to rabbit bone gelatinase that identifies high and low Mr forms. J Cell Sci 1989 1.10
49 The effect of two diphosphonates on the resorption of mouse calvaria in vitro. Calcif Tissue Res 1972 1.07
50 Inhibition of bone resorption by selective inactivators of cysteine proteinases. J Cell Biochem 1994 1.06
51 Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor. J Periodontal Res 1982 1.06
52 Human osteoblasts in culture synthesize collagenase and other matrix metalloproteinases in response to osteotropic hormones and cytokines. J Cell Sci 1992 1.04
53 Characterization of collagenase, other metallo-proteinases and an inhibitor (TIMP) produced by human synovium and cartilage in culture. Clin Sci (Lond) 1981 1.04
54 Advances in understanding cell interactions in tissue resorption. Relevance to the pathogenesis of periodontal diseases and a new hypothesis. J Oral Pathol 1986 1.03
55 The effect of ascorbic acid on the growth of chick bone rudiments in chemically defined medium. Exp Cell Res 1966 1.03
56 Production of collagenase and inhibitor (TIMP) by normal, rheumatoid and osteoarthritic synovium in vitro: effects of hydrocortisone and indomethacin. Clin Sci (Lond) 1981 1.03
57 Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function. Endocrinology 1995 0.99
58 Gelatinase A (MMP-2) and cysteine proteinases are essential for the degradation of collagen in soft connective tissue. Matrix Biol 1998 0.99
59 The role of vitamin D metabolites in bone resorption. Calcif Tissue Res 1973 0.97
60 Tissue inhibitor of metalloproteinases (TIMP) regulates extracellular type I collagen degradation by chondrocytes and endothelial cells. J Cell Sci 1987 0.95
61 A factor synthesized by rabbit periosteal fibroblasts stimulates bone resorption and collagenase production by connective tissue cells in vitro. Biochim Biophys Acta 1984 0.95
62 Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts. Biochem J 1994 0.95
63 Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase. Biochem J 1995 0.94
64 Metalloproteinases and cancer invasion and metastasis. Int J Cancer 1989 0.94
65 Metalloproteinases are not involved in the phagocytosis of collagen fibrils by fibroblasts. Matrix 1989 0.92
66 Proteoglycan-degrading enzymes of rabbit fibroblasts and granulocytes. Biochem J 1978 0.92
67 Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture. Biochim Biophys Acta 1983 0.92
68 The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis. I. Synovium. Rheumatol Int 1981 0.92
69 Rabbit cranial suture fibroblasts under tension express a different collagen phenotype. Arch Oral Biol 1982 0.91
70 1,25-Dihydroxycholecalciferol increases bone resorption in thyroparathyroidectomised mice. Calcif Tissue Res 1976 0.91
71 Production of collagenase by human osteoblasts and osteoclasts in vivo. Bone 1996 0.90
72 The effect of hydrocortisone on the growth of chick bone rudiments in chemically defined medium. Exp Cell Res 1966 0.90
73 Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone. Cell Tissue Res 2000 0.89
74 Effect of streptococcal cell wall components on bone metabolism in vitro. Calcif Tissue Int 1982 0.89
75 The molecular and cellular interactions involved in connective tissue destruction. Br J Dermatol 1985 0.89
76 Gingival fibroblasts degrade type I collagen films when stimulated with tumor necrosis factor and interleukin 1: evidence that breakdown is mediated by metalloproteinases. J Periodontal Res 1989 0.89
77 A sensitive in vitro method for studying the induction and inhibition of bone resorption. Calcif Tissue Res 1970 0.88
78 Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells. Infect Immun 1987 0.88
79 The binding of rabbit bone inhibitor of collagenase to concanavalin A--Sepharose [proceedings]. Biochem Soc Trans 1980 0.88
80 Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases. Biochem J 1992 0.87
81 Evidence that species specificity and rate of collagen degradation are properties of collagen, not collagenase. Biochim Biophys Acta 1977 0.87
82 Effects of retinol and dexamethasone on cytokine-mediated control of metalloproteinases and their inhibitors by human articular chondrocytes and synovial cells in culture. Biochim Biophys Acta 1983 0.87
83 Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13. Biochemistry 1992 0.86
84 Inhibition by diphosphonates of bone resorption in mice and comparison with grey-lethal osteopetrosis. Calcif Tissue Res 1973 0.86
85 The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis. II. Articular cartilage. Rheumatol Int 1981 0.86
86 The effects of vitamin D analogues on bone resorption. Calcif Tissue Res 1974 0.85
87 Effects of products from macrophages, blood mononuclear cells and or retinol on collagenase secretion and collagen synthesis in chondrocyte culture. Biochim Biophys Acta 1982 0.85
88 Collagenase and collagenase inhibitor levels following changes in bone resorption in vitro. Calcif Tissue Int 1980 0.85
89 Effect of tensile mechanical stress on the synthesis of metalloproteinases by rabbit coronal sutures in vitro. Calcif Tissue Int 1980 0.84
90 An inhibitor of mammalian collagenase from foetal rabbit bone in culture. Biochem Soc Trans 1977 0.84
91 Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone. J Anat 1997 0.83
92 Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients. J Periodontal Res 1994 0.83
93 A fibrosarcoma model derived from mouse embryo cells: growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines. Int J Cancer 1984 0.83
94 Inhibition of stimulated bone resorption in vitro by TIMP-1 and TIMP-2. Biochim Biophys Acta 1993 0.83
95 Matrix metalloproteinases in the formation of human synovial joint cavities. J Anat 1996 0.82
96 Messenger function of prostaglandins in cell to cell interactions and control of proteinase activity in the rheumatoid joint. Int J Immunopharmacol 1982 0.82
97 The effects of serine proteinase inhibitors on bone resorption in vitro. J Endocrinol 2003 0.82
98 Effect of poly DL-lactide--co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit. Biomaterials 1994 0.82
99 The release of interleukin-1 beta, tumor necrosis factor-alpha and interferon-gamma by cultured peripheral blood mononuclear cells from patients with periodontitis. J Periodontal Res 1990 0.82
100 Zinc metalloenzyme properties of active and latent collagenase from rabbit bone. Biochem J 1981 0.82
101 Tissue inhibitor of metalloproteinases and collagenase inhibitory activity in lung secretions from patients with chronic obstructive bronchitis: effect of corticosteroid treatment. Thorax 1986 0.81
102 Rabbit cranial sutures in vitro: a new experimental model for studying the response of fibrous joints to mechanical stress. Calcif Tissue Int 1979 0.81
103 Collagenase activity from cultured non-gravid rabbit uterus. Biochem Soc Trans 1977 0.81
104 Rabbit models of arthritis: immunolocalization of matrix metalloproteinases and tissue inhibitor of metalloproteinase in synovium and cartilage. Am J Pathol 1993 0.81
105 Matrix metalloproteinases and TIMP-1 localization at sites of osteogenesis in the craniofacial region of the rabbit embryo. Anat Rec 1995 0.80
106 The effects of razoxane (ICRF 159) on the production of collagenase and inhibitor (TIMP) by stimulated rabbit articular chondrocytes. Biochem Pharmacol 1983 0.80
107 Bone-derived growth factors modulate collagenase and TIMP (tissue inhibitor of metalloproteinases) activity and type I collagen degradation by mouse calvarial osteoblasts. Bone Miner 1991 0.80
108 Stromelysin (MMP-3) synthesis is up-regulated in estrogen-deficient mouse osteoblasts in vivo and in vitro. J Bone Miner Res 1999 0.80
109 Degradation processes in bone and cartilage. Calcif Tissue Res 1970 0.79
110 The purification and partial characterization of bone resorptive polypeptides from bovine bone matrix. Biochim Biophys Acta 1994 0.79
111 The effects of dexamethasone in vitro on the production of collagenase and inhibitor by synovial and cartilage explants from the joints of rabbits with a proliferative arthritis. Rheumatol Int 1981 0.79
112 Degradation of type I collagen films by mouse osteoblasts is stimulated by 1,25 dihydroxyvitamin D3 and inhibited by human recombinant TIMP (tissue inhibitor of metalloproteinases). Biochem Biophys Res Commun 1987 0.79
113 Porcine collagenase from synovial fibroblasts: cDNA sequence and modulation of expression of RNA in vitro by various cytokines. Matrix 1991 0.78
114 Regional and temporal changes in the synthesis of matrix metalloproteinases and TIMP-1 during development of the rabbit mandibular condyle. J Anat 1994 0.78
115 Properties of rheumatoid and normal synovial tissue in vitro and cells derived from them. Production of prostaglandins and collagenase in response to factors derived from cultured blood mononuclear cells and from synovium. Rheumatol Int 1982 0.78
116 The synthesis of collagenase, gelatinase-A (72 kDa) and -B (95 kDa), and TIMP-1 and -2 by human osteoblasts from normal and arthritic bone. Bone 1995 0.78
117 The degradation of collagen in pig synovium in vitro and the effect of colchicine. Matrix 1989 0.78
118 Production of collagenase and inhibitor (TIMP) by intracranial tumors and dura in vitro. J Neurosurg 1983 0.78
119 Type I collagen degradation by mouse calvarial osteoblasts stimulated with 1,25-dihydroxyvitamin D-3: evidence for a plasminogen-plasmin-metalloproteinase activation cascade. Biochim Biophys Acta 1989 0.77
120 A second plasma calcium-lowering peptide from the human calcitonin precursor. Nature 1982 0.77
121 Stromelysin, gelatinase A and TIMP-1 in prosthetic interface tissue: a role for macrophages in tissue remodelling. Histopathology 1995 0.77
122 Time course of action of calcitonin on resorbing mouse bones in vitro. Nature 1968 0.77
123 Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts. Matrix 1989 0.77
124 Interactions in connective tissues involving monocyte/macrophages and control of production of proteinases and proteinase inhibitors. Agents Actions Suppl 1982 0.76
125 Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in mechanically deformed fibrous joints. Am J Orthod Dentofacial Orthop 1990 0.76
126 Metalloproteinase production by rabbit articular cartilage: comparison of the effects of interleukin-1 alpha in vitro and in vivo. Virchows Arch 1994 0.76
127 The use of in vitro models for investigating the response of fibrous joints to tensile mechanical stress. Am J Orthod 1984 0.76
128 Rabbit collagenase. Immunological identity of the enzymes released from cells and tissues in normal and pathological conditions. Biochem J 1975 0.75
129 Osteopetrotic (grey-lethal) bone produces collagenase and TIMP in organ culture: regulation by vitamin A. Biochem Biophys Res Commun 1990 0.75
130 The induction and inhibition of bone resorption in vitro. Calcif Tissue Res 1968 0.75
131 A second plasma calcium-lowering peptide from the human calcitonin precursor--a re-evaluation. Nature 1984 0.75
132 Comparison of the inhibition of avian and mammalian bone alkaline phosphatases by levamisole and compound R8231. Experientia 1977 0.75
133 The promotion and inhibition of collagen-breakdown in organ cultures of pig synovium: the requirement for serum components and the involvement of cyclic adenosine 3':5'-monophosphate (cAMP). Coll Relat Res 1986 0.75
134 Social work, survival, and the commercialization of health care. The newest challenge. Health Soc Work 1987 0.75
135 Inhibitory effect of salmon and other calcitonins on calcium release from mouse bone in vitro. Can J Physiol Pharmacol 1971 0.75
136 Bone-derived growth factor release from poly(alpha-hydroxy acid) implants in vitro. Biomaterials 1993 0.75
137 Rabbit calvarial osteoblasts in culture constitutively synthesize progelatinase-A, and TIMP-1 and TIMP-2. Biochim Biophys Acta 1994 0.75
138 Effect of environmental factors on the repair of bone in vitro. J Bone Joint Surg Br 1968 0.75
139 Identification of matrix metalloproteinases and their inhibitor in the articular disc of the craniomandibular joint of the rabbit. Arch Oral Biol 1996 0.75
140 The expression of matrix metalloproteinases and their inhibitors by pig synovial cells and their regulation by combinations of cytokines and growth factors. Comp Biochem Physiol B 1993 0.75
141 Love, medicine, and money: issues of access, use, and advocacy. Health Soc Work 1989 0.75
142 Inhibition of production and action of tissue metalloproteinases. Ann Biol Clin (Paris) 1986 0.75
143 The synthesis of collagen by chick bone rudiments in vitro. Exp Cell Res 1967 0.75
144 Clinical dimensions of discharge planning with the person with AIDS. Soc Work 1991 0.75
145 Species discrimination between calcitonins. Lancet 1968 0.75
146 An in vitro bioassay for 1,25-dihydroxyvitamin D3 and other antirachitic agents. Mol Cell Endocrinol 1977 0.75
147 The structure of senegenic acid, a nortriterpene artifact from Polygala senega. J Org Chem 1965 0.75
148 Case management as gatekeeping and utilization review: is the end in sight? Continuum Soc Soc Work Leadersh Health Care 2001 0.75
149 The effect of parathyroid hormone and vitamin D3 metabolites on CaBP synthesis by embryonic duodenum, in vitro. Horm Metab Res 1978 0.75
150 Inhibitory effect of follicle stimulating hormone on parathormone in the mouse--a possible explanation of postmenopausal osteoporosis. Isr J Med Sci 1982 0.75
151 The effects of antirheumatic drugs on the production of collagenase and tissue inhibitor of metalloproteinases (TIMP) by stimulated rabbit articular chrondrocytes. J Rheumatol 1984 0.75
152 The response of mouse bones to calcitonin preparations from different species. Calcif Tissue Res 1970 0.75
153 CaBP production by chick duodenum in vitro in response to vitamin D3, its metabolites and PTH. Calcif Tissue Res 1977 0.75