Published in J Chromatogr A on July 07, 1995
Oxidative stress, nitric oxide, and diabetes. Rev Diabet Stud (2010) 1.43
Oxidative stress in diabetes: implications for vascular and other complications. Int J Mol Sci (2013) 1.13
Evaluation of leukocyte esterase and nitrite strip tests to detect spontaneous bacterial peritonitis in cirrhotic patients. World J Gastroenterol (2007) 0.81
Reduced capacity of tumour blood vessels to produce endothelium-derived relaxing factor: significance for blood flow modification. Br J Cancer (1996) 0.80
Oxidative denitrification of N omega-hydroxy-L-arginine by the superoxide radical anion. Biochem J (1996) 0.78
Guidelines for the welfare and use of animals in cancer research. Br J Cancer (2010) 6.97
Electron-affinic sensitization. VII. A correlation between structures, one-electron reduction potentials, and efficiencies of nitroimidazoles as hypoxic cell radiosensitizers. Radiat Res (1976) 3.44
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res (1997) 2.96
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. Br J Cancer (2005) 2.85
Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues. Cancer Res (1999) 1.79
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res (2001) 1.75
The use of nitroaromatic compounds as hypoxic cell radiosensitizers. Curr Top Radiat Res Q (1977) 1.63
Mammalian cell toxicity of nitro compounds : dependence upon reduction potential. Biochem Biophys Res Commun (1976) 1.53
Structure-activity relationships in the development of hypoxic cell radiosensitizers. I. Sensitization efficiency. Int J Radiat Biol Relat Stud Phys Chem Med (1979) 1.47
An assessment of 31P MRS as a method of measuring pH in rat tumours. NMR Biomed (1993) 1.45
Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer (2000) 1.44
Interaction of dGMP radical with cysteamine and promethazine as possible model of DNA repair. Nature (1974) 1.42
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res (2001) 1.32
Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233). Biochem Pharmacol (1988) 1.28
Kinetics and mechanisms of hypochlorous acid reactions. Arch Biochem Biophys (1995) 1.28
Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers. Radiother Oncol (1992) 1.27
Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials. Br J Radiol (2003) 1.27
Smoking in help-seeking veterans with PTSD returning from Afghanistan and Iraq. Addict Behav (2008) 1.24
Oxygen inhibition of nitroreductase: electron transfer from nitro radical-anions to oxygen. Biochem Biophys Res Commun (1976) 1.20
Tumour vascular disrupting agents: combating treatment resistance. Br J Radiol (2008) 1.19
Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis. Biochem Biophys Res Commun (2001) 1.19
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study. Arch Biochem Biophys (1988) 1.17
Free hydroxyl radicals are formed on reaction between the neutrophil-derived species superoxide anion and hypochlorous acid. FEBS Lett (1993) 1.17
Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential. J Natl Cancer Inst (1980) 1.14
Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection. Br J Cancer (1991) 1.11
Kinetic modeling of hyperpolarized (13)C pyruvate metabolism in tumors using a measured arterial input function. Magn Reson Med (2012) 1.09
The effect of radiosensitizers on the pharmacokinetics of melphalan and cyclophosphamide in the mouse. Br J Cancer (1983) 1.08
Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy. Biochem Pharmacol (2001) 1.07
Neurotoxicity with desmethylmisonidazole. Br J Radiol (1981) 1.06
Electroporation of human microvascular endothelial cells: evidence for an anti-vascular mechanism of electrochemotherapy. Br J Cancer (2001) 1.03
Measurement of tumor oxygenation: in vivo comparison of a luminescence fiber-optic sensor and a polarographic electrode in the p22 tumor. Radiat Res (2001) 1.02
Cellular uptake of misonidazole and analogues with acidic or basic functions. Int J Radiat Biol Relat Stud Phys Chem Med (1985) 1.02
The use of ketamine plus diazepam anaesthesia to increase the radiosensitivity of a C3H mouse mammary adenocarcinoma in hyperbaric oxygen. Br J Radiol (1984) 1.01
In vivo assessment of basic 2-nitroimidazole radiosensitizers. Br J Cancer (1982) 1.00
Bioreductive fluorescent markers for hypoxic cells: a study of 2-nitroimidazoles with 1-substituents containing fluorescent, bridgehead-nitrogen, bicyclic systems. J Med Chem (1992) 1.00
Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide. Br J Cancer (2000) 0.99
Limitations of the reporter green fluorescent protein under simulated tumor conditions. Cancer Res (2001) 0.99
An automatic algorithm for the segmentation and morphological analysis of microvessels in immunostained histological tumour sections. J Microsc (2010) 0.98
Structure-activity relationships in the development of hypoxic cell radiosensitizers. II. Cytotoxicity and therapeutic ratio. Int J Radiat Biol Relat Stud Phys Chem Med (1979) 0.98
A drug for improved radiosensitization in radiotherapy. Br J Cancer (1980) 0.96
The energy metabolism of RIF-1 tumours following hydralazine. Radiother Oncol (1990) 0.96
Free-radical repair by a novel perthiol: reversible hydrogen transfer and perthiyl radical formation. Free Radic Res (1994) 0.96
Radicals from one-electron reduction of nitro compounds, aromatic N-oxides and quinones: the kinetic basis for hypoxia-selective, bioreductive drugs. Biochem Soc Symp (1995) 0.95
A serial study of the concentration of misonidazole in human tumors correlated with histologic structure. Int J Radiat Oncol Biol Phys (1981) 0.95
Effect of local radiotherapy for bone pain on urinary markers of osteoclast activity. Lancet (2000) 0.95
Nitric oxide production by tumour tissue: impact on the response to photodynamic therapy. Br J Cancer (2000) 0.95
Kinetics of superoxide scavenging by glutathione: an evaluation of its role in the removal of mitochondrial superoxide. Biochem Soc Trans (2003) 0.94
Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. Cancer Res (1997) 0.94
Characterisation of tumour blood flow using a 'tissue-isolated' preparation. Br J Cancer (1994) 0.93
Formation of hydroxyl radicals on reaction of hypochlorous acid with ferrocyanide, a model iron(II) complex. Free Radic Res (1994) 0.93
Ischemia reperfusion injury in tumors: the role of oxygen radicals and nitric oxide. Cancer Res (1995) 0.93
The concentration of desmethylmisonidazole in human tumours and in cerebrospinal fluid. Br J Cancer (1981) 0.93
Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid. Cancer Gene Ther (2000) 0.93
Perthiols as antioxidants: radical-scavenging and prooxidative mechanisms. Methods Enzymol (1995) 0.92
Measurement of oxygen tension in tumours by time-resolved fluorescence. Br J Cancer Suppl (1996) 0.92
Factors controlling the substrate specificity of peroxidases: kinetics and thermodynamics of the reaction of horseradish peroxidase compound I with phenols and indole-3-acetic acids. Biochemistry (1997) 0.92
The relationship between extracellular lactate and tumour pH in a murine tumour model of ischaemia-reperfusion. Br J Cancer (1997) 0.91
Antineoplastic agents 393. Synthesis of the trans-isomer of combretastatin A-4 prodrug. Anticancer Drug Des (1998) 0.91
One-electron reduction of 2- and 6-methyl-1,4-naphthoquinone bioreductive alkylating agents. J Med Chem (1986) 0.91
Nicotinamide pharmacokinetics in normal volunteers and patients undergoing palliative radiotherapy. Acta Oncol (1996) 0.90
Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions. Mol Cancer Ther (2001) 0.90
Measuring the velocity of fluorescently labelled red blood cells with a keyhole tracking algorithm. J Microsc (2008) 0.90
Some reactions and properties of nitro radical-anions important in biology and medicine. Environ Health Perspect (1985) 0.89
Enhancement of lipid peroxidation by indole-3-acetic acid and derivatives: substituent effects. Free Radic Res (1995) 0.89
Glutathione determination by the Tietze enzymatic recycling assay and its relationship to cellular radiation response. Br J Cancer (1995) 0.89
Measurement of tumor oxygenation: a comparison between polarographic needle electrodes and a time-resolved luminescence-based optical sensor. Radiat Res (1997) 0.89
Administration of nicotinamide during chart: pharmacokinetics, dose escalation, and clinical toxicity. Int J Radiat Oncol Biol Phys (1995) 0.89
Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. Clin Chim Acta (2001) 0.88
The combined measurement of blood flow and metabolism in RIF-1 tumours in vivo. A study using H2 flow and 31P NMR spectroscopy. NMR Biomed (1990) 0.88
The influence of vasoactive agents on the perfusion of tumours growing in three sites in the mouse. Int J Radiat Biol (1991) 0.88
High-performance liquid chromatographic determination of nicotinamide and its metabolites in human and murine plasma and urine. J Chromatogr (1992) 0.88
The effects of hyperoxic and hypercarbic gases on tumour blood flow. Br J Cancer (1999) 0.88
Factors influencing the chemosensitization of melphalan by misonidazole. Br J Cancer (1985) 0.87
The influence of nitric oxide on tumour vascular tone. Acta Oncol (1995) 0.87
Clinical experience with nitroimidazoles as radiosensitizers. Int J Radiat Oncol Biol Phys (1982) 0.87
Modification of tumor blood flow: current status and future directions. Semin Radiat Oncol (1998) 0.87
Effect of anemia on tumor radiosensitivity under normo and hyperbaric conditions. Int J Radiat Oncol Biol Phys (1987) 0.87
Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro. Biochem Pharmacol (1999) 0.87
Metabolic and clonogenic consequences of ischaemia reperfusion insult in solid tumours. Exp Physiol (1997) 0.87
Ruby laser irradiation (694 nm) of human skin biopsies: assessment by electron spin resonance spectroscopy of free radical production and oxidative stress during laser depilation. Photochem Photobiol (1999) 0.86
Toward targeted "oxidation therapy" of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids. Int J Radiat Oncol Biol Phys (1998) 0.86