Published in Adv Immunol on January 01, 1977
Antigen recognition by cloned cytotoxic T lymphocytes follows rules predicted by the altered-self hypothesis. J Exp Med (1982) 1.80
Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells. Proc Natl Acad Sci U S A (1978) 1.58
Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex. J Exp Med (1979) 1.48
Hapten-reactive inducer T cells. I. Definition of two classes of hapten-specific inducer cells. J Exp Med (1983) 1.33
Dissociation and exchange of the beta 2-microglobulin subunit of HLA-A and HLA-B antigens. Proc Natl Acad Sci U S A (1979) 1.31
Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus. J Exp Med (1983) 1.30
Identification of a fourth class of proteins linked to the murine major histocompatibility complex. Proc Natl Acad Sci U S A (1982) 1.27
HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus. J Exp Med (1979) 1.23
Immunohistochemical analysis of HLA (A, B, C) antigens in liver disease using a monoclonal antibody. Gut (1981) 1.23
Primary structural studies of an H-2L molecule confirm that it is a unique gene product with homology to H-2K and H-2D antigens. Proc Natl Acad Sci U S A (1980) 1.14
Quantitative differences in the expression of parentally-derived H-2 antigens in F1 hybrid mice affect T-cell responses. J Exp Med (1979) 1.12
Autoimmune diseases: immunopathology and etiopathogenesis. Am J Pathol (1982) 1.07
High-level expression of a cloned HLA heavy chain gene introduced into mouse cells on a bovine papillomavirus vector. Mol Cell Biol (1984) 0.99
Gluten-sensitive enteropathy. Influence of histocompatibility type on gluten sensitivity in vitro. J Clin Invest (1980) 0.99
T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes. J Exp Med (1980) 0.95
Murine retroviruses control class I major histocompatibility antigen gene expression via a trans effect at the transcriptional level. Mol Cell Biol (1987) 0.95
Monoclonal antibodies against human Ia antigens stimulate monocytes to secrete interleukin 1. Proc Natl Acad Sci U S A (1985) 0.92
T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten-specific cytolytic T lymphocytes. J Exp Med (1980) 0.89
Reversal of the metastatic phenotype in Lewis lung carcinoma cells after transfection with syngeneic H-2Kb gene. Proc Natl Acad Sci U S A (1988) 0.89
Binding of purified, soluble major histocompatibility complex polypeptide chains onto isolated T-cell receptors. I. Reactivity against allo- and self-determinants. J Exp Med (1979) 0.86
Role of self carriers in the immune response and tolerance. V. Reversal of trinitrophenyl-modified self suppression of the B-cell response by blocking of H-2 antigens. J Exp Med (1980) 0.84
Adoptive transfer of cross-protection among alphaviruses in mice requires allogeneic stimulation. Infect Immun (1979) 0.82
Analysis of cross-reactive antigen-specific T cell clones. Specific recognition of two major histocompatibility complex (MHC) and two non-MHC antigens by a single clone. J Exp Med (1983) 0.81
Regulation of T-cell-mediated lympholysis by the murine major histocompatibility complex. II. Control of cytotoxic responses to trinitrophenyl-K and -D self products by H-2K- and H-2D-Region genes. J Exp Med (1980) 0.81
H-2 restriction: independent recognition of H-2 and foreign antigen by a single receptor. Proc Natl Acad Sci U S A (1980) 0.80
Influence of monoclonal anti-Ia like antibodies on activation of human lymphocytes. Immunology (1982) 0.78
Genetic restriction of cytolysis during equid herpesvirus 1 subtype 2 infection. Clin Exp Immunol (1987) 0.77
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science (1984) 32.33
A TH1-->TH2 switch is a critical step in the etiology of HIV infection. Immunol Today (1993) 10.43
Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes. Eur J Immunol (1974) 6.20
Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester. Nature (1985) 5.06
Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol (1991) 4.69
Modulation of inflammation and immunity by cyclic AMP. Science (1974) 4.31
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging. J Clin Invest (1989) 3.92
Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I. T cell recognition of TNP in association with widely shared antigens. J Immunol (1978) 3.90
Role of the murine major histocompatibility complex in the specificity of in vitro T-cell-mediated lympholysis against chemically-modified autologous lymphocytes. Transplant Rev (1976) 3.87
Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1. J Infect Dis (1992) 3.27
Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals. J Clin Invest (1993) 3.19
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus. J Clin Invest (1994) 3.12
Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts. Eur J Immunol (1977) 3.05
The Th1-Th2 hypothesis of HIV infection: new insights. Immunol Today (1994) 3.01
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. Cell (1991) 2.83
Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev (1996) 2.77
Cellular differentiation of the immune system of mice. I. Separate splenic antigen-sensitive units for different types of anti-sheep antibody-forming cells. J Exp Med (1968) 2.51
Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection. J Natl Cancer Inst (1997) 2.45
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat Immunol (2000) 2.37
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro. Science (1993) 2.35
Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33
A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS). J Immunol (1986) 2.31
Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets. EMBO J (1987) 2.20
An immunoendocrinological hypothesis of HIV infection. Lancet (1994) 2.19
Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals. J Immunol (1991) 2.17
Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes. J Exp Med (1975) 2.14
Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels. Am J Cardiol (2000) 2.05
ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids. J Clin Invest (1995) 2.04
Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes. Cell (1987) 2.00
Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive hormones. J Clin Invest (1974) 1.98
Early T-helper cell defects in HIV infection. AIDS (1991) 1.93
CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells. J Immunol (1991) 1.82
Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals. Nature (1989) 1.80
Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals. J Clin Invest (1989) 1.77
B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation. Science (1974) 1.73
Distinct events in the immune response elicited by transferred marrow and thymus cells. I. Antigen requirements and priferation of thymic antigen-reactive cells. J Exp Med (1969) 1.72
Regulation of antibody response by cells expressing histamine receptors. J Exp Med (1972) 1.70
In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus. J Infect Dis (1995) 1.69
H-2-restricted cytotoxic effectors generated in vitro by the addition of trinitrophenyl-conjugated soluble proteins. J Exp Med (1978) 1.68
Multiplex messenger assay: simultaneous, quantitative measurement of expression of many genes in the context of T cell activation. Nucleic Acids Res (1996) 1.67
T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. Immunol Today (1989) 1.66
Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease. J Immunol (1987) 1.64
The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14. Nature (1986) 1.61
Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses. J Exp Med (1980) 1.61
Human immunodeficiency virus type 1 (HIV-1)-seronegative injection drug users at risk for HIV exposure have antibodies to HLA class I antigens and T cells specific for HIV envelope. J Infect Dis (1996) 1.61
Alloimmunization as an AIDS vaccine? Science (1993) 1.58
T cell subpopulations required for the human cytotoxic T lymphocyte response to influenza virus: evidence for T cell help. J Immunol (1981) 1.54
Functional and phenotypic alterations in T cell subsets during the course of MAIDS, a murine retrovirus-induced immunodeficiency syndrome. J Immunol (1989) 1.53
Exposure to human immunodeficiency virus (HIV) type I indicated by HIV-specific T helper cell responses before detection of infection by polymerase chain reaction and serum antibodies [corrected]. J Infect Dis (1991) 1.53
Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans. Nature (1988) 1.53
Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci U S A (1994) 1.53
Thymus-independence of slowly metabolized immunogens. Proc Natl Acad Sci U S A (1972) 1.52
Alloantigen-stimulated anti-HIV activity. Blood (1998) 1.51
Cellular differentiation of the immune system of mice. V. Class differentiation in marrow precursors of plaque-forming cells. J Exp Med (1969) 1.50
Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types. J Clin Invest (1991) 1.44
Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen. Immunol Rev (1991) 1.43
In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10. J Infect Dis (1996) 1.41
T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. Eur J Immunol (1994) 1.40
Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology. Cancer Res (1996) 1.39
Cell types required for H-2-restricted cytotoxic responses generated by trinitrobenzene sulfonate-modified syngeneic cells or trinitrophenyl-conjugated proteins. J Immunol (1979) 1.38
A strategy for prophylactic vaccination against HIV. Science (1993) 1.38
Genetic control of the immune response to staphylococcal nuclease. I. Ir-Nase: control of the antibody response to nuclease by the Ir region of the mouse H-2 complex. J Exp Med (1974) 1.36
HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood. JAMA (1994) 1.36
Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus. J Infect Dis (1996) 1.36
Pleiotropic loss of activation pathways in a T-cell receptor alpha-chain deletion variant of a cytolytic T-cell clone. Nature (1987) 1.34
Genetic control of immune responses. Curr Top Microbiol Immunol (1972) 1.34
T-cell proliferation to subinfectious SIV correlates with lack of infection after challenge of macaques. AIDS (1994) 1.32
Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen. Int Immunol (1992) 1.32
Cellular differentiation of the immune system of mice. IV. Lack of class differentiation in thymic antigen-reactive cells. J Exp Med (1969) 1.31
Engineered secreted T-cell receptor alpha beta heterodimers. Proc Natl Acad Sci U S A (1991) 1.30
HIV-1-specific cellular immune responses among HIV-1-resistant sex workers. Immunol Cell Biol (2000) 1.29
An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1990) 1.28
Cell-mediated lympholysis to H-2-matched target cells modified with a series of nitrophenyl compounds. J Exp Med (1976) 1.27
Cellular differentiation of the immune system of mice. II. Frequency of unipotent splenic antigen-sensitive units after immunization with sheep erythrocytes. J Exp Med (1969) 1.26
The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens. J Immunol (1980) 1.25
The role of thymus cells in the immune response to poly(Tyr, Glu)-polyD L Ala--polyLys as a function of the genetic constitution of the mouse strain. Eur J Immunol (1974) 1.24
Cellular differentiation of the immune system of mice. 3. Separate antigen-sensitive units for different types of anti-sheep immunocytes formed by marrow-thymus cell mixtures. J Exp Med (1969) 1.23
T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission. AIDS (2001) 1.23
Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules. Hum Immunol (1980) 1.22
Cluster formation in vitro by mouse spleen cells and sheep erythrocytes. J Immunol (1968) 1.21
Influence of human immunodeficiency virus-infected maternal environment on development of infant interleukin-12 production. J Infect Dis (2000) 1.21
Genetic control of the immune response to staphylococcal nuclease. III. Time-course and correlation between the response to native nuclease and the response to its polypeptide fragments. J Exp Med (1977) 1.20
HIV type 1 resistance in Kenyan sex workers is not associated with altered cellular susceptibility to HIV type 1 infection or enhanced beta-chemokine production. AIDS Res Hum Retroviruses (1998) 1.19
Lymphoid cell surface interaction structures detected using cytolysis-inhibiting monoclonal antibodies. Immunol Rev (1982) 1.18
In vitro induction of F1 hybrid anti-parent cell-mediated cytotoxicity. J Immunol (1976) 1.16
Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease. J Exp Med (1977) 1.15