A TH1-TH2-like switch in candidiasis: new perspectives for therapy.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 7648032)

Published in Trends Microbiol on June 01, 1995

Authors

P Puccetti1, L Romani, F Bistoni

Author Affiliations

1: Dept of Experimental Medicine, University of Rome Tor Vergata, Italy.

Articles citing this

Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo. J Exp Med (2000) 2.99

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans. J Exp Med (1996) 2.41

Immunopathogenesis of recurrent vulvovaginal candidiasis. Clin Microbiol Rev (1996) 1.90

Comparison of pathogenesis and host immune responses to Candida glabrata and Candida albicans in systemically infected immunocompetent mice. Infect Immun (2001) 1.75

Macrophages in resistance to candidiasis. Microbiol Mol Biol Rev (1997) 1.74

Interleukin-12 in infectious diseases. Clin Microbiol Rev (1997) 1.63

Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice. Infect Immun (2000) 1.39

Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans. J Exp Med (1998) 1.37

CD4+ T-helper-cell responses in mice with low-level Candida albicans infection. Infect Immun (1996) 1.18

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug. Front Microbiol (2012) 1.11

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study. Clin Infect Dis (2011) 1.00

Generation of a recombinant 65-kilodalton mannoprotein, a major antigen target of cell-mediated immune response to Candida albicans. Infect Immun (2000) 0.99

Biochemical and immunological characterization of MP65, a major mannoprotein antigen of the opportunistic human pathogen Candida albicans. Infect Immun (2000) 0.89

Candida albicans and Candida krusei differentially induce human blood mononuclear cell interleukin-12 and gamma interferon production. Infect Immun (2000) 0.89

NK cells mediate increase of phagocytic activity but not of proinflammatory cytokine (interleukin-6 [IL-6], tumor necrosis factor alpha, and IL-12) production elicited in splenic macrophages by tilorone treatment of mice during acute systemic candidiasis. Clin Diagn Lab Immunol (2002) 0.85

Hybrid phage displaying SLAQVKYTSASSI induces protection against Candida albicans challenge in BALB/c mice. Hum Vaccin Immunother (2014) 0.82

Invasive candidiasis stimulates hepatocyte and monocyte production of active transforming growth factor beta. Infect Immun (2001) 0.81

Measurement of T-cell-derived antigen binding molecules and immunoglobulin G specific to Candida albicans mannan in sera of patients with recurrent vulvovaginal candidiasis. Infect Immun (2000) 0.76

Oral candidiasis, HIV, and saliva glucocorticoids. Am J Pathol (1996) 0.75

Articles by these authors

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol (1990) 4.37

Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice. EMBO J (1995) 3.48

Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo. J Exp Med (2000) 2.99

Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance. Infect Immun (1991) 2.46

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans. J Exp Med (1996) 2.41

Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis. J Exp Med (1992) 2.37

CD4+ subset expression in murine candidiasis. Th responses correlate directly with genetically determined susceptibility or vaccine-induced resistance. J Immunol (1993) 2.30

Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans. Eur J Immunol (1993) 2.05

Evidence for macrophage-mediated protection against lethal Candida albicans infection. Infect Immun (1986) 1.86

An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasis. J Immunol (1997) 1.76

IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol (2010) 1.76

IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis. J Immunol (1994) 1.75

Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. J Immunol (1994) 1.72

Purified capsular polysaccharide of Cryptococcus neoformans induces interleukin-10 secretion by human monocytes. Infect Immun (1996) 1.71

A mannoprotein constituent of Candida albicans that elicits different levels of delayed-type hypersensitivity, cytokine production, and anticandidal protection in mice. Infect Immun (1994) 1.68

Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice. J Immunol (1997) 1.68

Interleukin-12 in infectious diseases. Clin Microbiol Rev (1997) 1.63

Th1 and Th2 cytokines in mice with invasive aspergillosis. Infect Immun (1997) 1.61

Postgrafting administration of granulocyte colony-stimulating factor impairs functional immune recovery in recipients of human leukocyte antigen haplotype-mismatched hematopoietic transplants. Blood (2001) 1.60

Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis. J Infect Dis (2008) 1.57

Role of L3T4+ lymphocytes in protective immunity to systemic Candida albicans infection in mice. Infect Immun (1989) 1.56

Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils. Infect Immun (1996) 1.53

Rapid methods to extract DNA and RNA from Cryptococcus neoformans. FEMS Yeast Res (2001) 1.52

Multicenter comparative evaluation of six commercial systems and the national committee for clinical laboratory standards m27-a broth microdilution method for fluconazole susceptibility testing of Candida species. J Clin Microbiol (2002) 1.51

Role of human alveolar macrophages as antigen-presenting cells in Cryptococcus neoformans infection. Am J Respir Cell Mol Biol (1994) 1.51

In vitro production of tumor necrosis factor by murine splenic macrophages stimulated with mannoprotein constituents of Candida albicans cell wall. Cell Immunol (1991) 1.49

T cell vaccination in mice with invasive pulmonary aspergillosis. J Immunol (2000) 1.48

The A-domain and the thrombospondin-related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands. EMBO J (1999) 1.47

Correlation between in vivo and in vitro studies of modulation of resistance to experimental Candida albicans infection by cyclophosphamide in mice. Infect Immun (1983) 1.43

T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development. J Infect Dis (1995) 1.41

Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice. Infect Immun (2000) 1.39

Cytokine- and T helper-dependent lung mucosal immunity in mice with invasive pulmonary aspergillosis. J Infect Dis (1998) 1.39

Cell wall components of Candida albicans as immunomodulators: induction of natural killer and macrophage-mediated peritoneal cell cytotoxicity in mice by mannoprotein and glucan fractions. J Gen Microbiol (1988) 1.38

Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans. J Exp Med (1998) 1.37

Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages. Clin Exp Immunol (1994) 1.37

Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii. Mol Cell Biol (2000) 1.36

Interleukin-12 but not interferon-gamma production correlates with induction of T helper type-1 phenotype in murine candidiasis. Eur J Immunol (1994) 1.33

In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells. J Immunol (1985) 1.30

T cell subsets and IFN-gamma production in resistance to systemic candidosis in immunized mice. J Immunol (1990) 1.29

Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. J Neuroimmunol (1995) 1.28

S100B expression in and effects on microglia. Glia (2001) 1.28

Antifungal type 1 responses are upregulated in IL-10-deficient mice. Microbes Infect (1999) 1.27

Interleukin-4 and -10 exacerbate candidiasis in mice. Eur J Immunol (1995) 1.27

Serodiagnosis of infectious diseases with antigen microarrays. J Appl Microbiol (2004) 1.25

Immunosuppressive effect of cyclosporin A on resistance to systemic infection with Candida albicans. J Med Microbiol (1989) 1.25

Protective immunity induced by low-virulence Candida albicans: cytokine production in the development of the anti-infectious state. Cell Immunol (1989) 1.21

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans. Mucosal Immunol (2009) 1.20

Natural cell-mediated cytotoxicity against Candida albicans induced by cyclophosphamide: nature of the in vitro cytotoxic effector. Infect Immun (1983) 1.20

Gamma interferon modifies CD4+ subset expression in murine candidiasis. Infect Immun (1992) 1.19

A comparison of experimental pathogenicity of Candida species in cyclophosphamide-immunodepressed mice. Sabouraudia (1984) 1.19

Interleukin-4 causes susceptibility to invasive pulmonary aspergillosis through suppression of protective type I responses. J Infect Dis (1999) 1.19

Iron overload alters innate and T helper cell responses to Candida albicans in mice. J Infect Dis (1997) 1.19

Cure of murine candidiasis by recombinant soluble interleukin-4 receptor. J Infect Dis (1994) 1.19

CD4+ T-helper-cell responses in mice with low-level Candida albicans infection. Infect Immun (1996) 1.18

Immunoadjuvant activity of amphotericin B as displayed in mice infected with Candida albicans. Antimicrob Agents Chemother (1985) 1.18

Encapsulation of Cryptococcus neoformans with glucuronoxylomannan inhibits the antigen-presenting capacity of monocytes. Infect Immun (1998) 1.16

NO-aspirin protects from T cell-mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines. Gastroenterology (2000) 1.13

Increase of mouse resistance to Candida albicans infection by thymosin alpha 1. Infect Immun (1982) 1.13

Dynamics of extracellular release of Aspergillus fumigatus DNA and galactomannan during growth in blood and serum. J Med Microbiol (2009) 1.13

Immunity to fungi: editorial overview. Res Immunol (1998) 1.12

IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection. J Immunol (1998) 1.12

Augmentation of GG2EE macrophage cell line-mediated anti-Candida activity by gamma interferon, tumor necrosis factor, and interleukin-1. Infect Immun (1990) 1.10

Experimental model of intracerebral infection with Cryptococcus neoformans: roles of phagocytes and opsonization. Infect Immun (1992) 1.10

[Use of potassium chloride hypertonic saline solution (3M KC1) for extraction of soluble antigens from Candida albicans]. Ann Sclavo (1976) 1.10

In-vitro killing of Candida species by murine immunoeffectors and its relationship to the experimental pathogenicity. Sabouraudia (1985) 1.09

IL-10 is required for development of protective Th1 responses in IL-12-deficient mice upon Candida albicans infection. J Immunol (1998) 1.09

Role of mannoprotein in induction and regulation of immunity to Cryptococcus neoformans. Infect Immun (2001) 1.08

Azole derivatives of 1,4-benzothiazine as antifungal agents. Bioorg Med Chem (1998) 1.08

Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells. J Infect Dis (1992) 1.07

Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. Int Immunol (1998) 1.07

Intracerebral transfer of an in vitro established microglial cell line: local induction of a protective state against lethal challenge with Candida albicans. J Neuroimmunol (1991) 1.07

Early induction of interleukin-12 by human monocytes exposed to Cryptococcus neoformans mannoproteins. Infect Immun (2000) 1.06

The contribution of PARs to inflammation and immunity to fungi. Mucosal Immunol (2008) 1.06

Impaired antifungal effector activity but not inflammatory cell recruitment in interleukin-6-deficient mice with invasive pulmonary aspergillosis. J Infect Dis (2001) 1.06

Impaired generation of bone marrow B lymphocytes in mice deficient in C/EBPbeta. Blood (1997) 1.06

Severity of group B streptococcal arthritis is correlated with beta-hemolysin expression. J Infect Dis (2000) 1.05

Chronic granulomatous disease. Cell Mol Life Sci (2009) 1.05

Inhibition of candidacidal activity of polymorphonuclear cells by alveolar macrophage-derived factor from lung cancer patients. Am Rev Respir Dis (1993) 1.05

Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: an ongoing dilemma or an unnecessary dispute? Med Mycol (1998) 1.04

Phagocytic killing of Candida albicans by different murine effector cells. Sabouraudia (1983) 1.04

A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis. Infect Immun (1998) 1.04

Biological role of Th cell subsets in candidiasis. Chem Immunol (1996) 1.04