The organisation of the axonal reticulum at a ligation, in in vitro incubated bovine splenic nerves.

Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics (1996) 3.56

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature (1999) 10.36

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature (1998) 7.43

Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci (2000) 3.38

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency. Proc Natl Acad Sci U S A (1999) 2.82

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells. Nat Cell Biol (2000) 2.53

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture. J Neurochem (2001) 1.73

The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein. J Cell Biol (2001) 1.46

Processing of beta-secretase by furin and other members of the proprotein convertase family. J Biol Chem (2000) 1.38

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability. Hum Mol Genet (2001) 1.33

Fusion of endosomes involved in synaptic vesicle recycling. Mol Biol Cell (1999) 1.29

Implication of APP secretases in notch signaling. J Mol Neurosci (2001) 1.09

Binding partners of Alzheimer's disease proteins: are they physiologically relevant? Neurobiol Dis (2000) 0.97

Presenilins and the intramembrane proteolysis of proteins: facts and fiction. Nat Cell Biol (2001) 0.96

Where Notch and Wnt signaling meet. The presenilin hub. J Cell Biol (2001) 0.95

Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. J Biol Chem (2001) 0.92

Gamma-secretase: never more enigmatic. Trends Neurosci (2001) 0.89

Alzheimer's presenilin 1 is a putative membrane receptor for rab GDP dissociation inhibitor. Hum Mol Genet (2000) 0.82

Alterations in GAP-43 and synapsin immunoreactivity provide evidence for synaptic reorganization in adult cat dorsal lateral geniculate nucleus following retinal lesions. Eur J Neurosci (1994) 0.82

Evidence for the co-storage and co-release of neuropeptide Y and noradrenaline from large dense cored vesicles in sympathetic nerves of the bovine vas deferens. Synapse (1988) 0.79

Presenilin 1: more than just gamma-secretase. Biochem Soc Trans (2005) 0.79

Chromogranin A processing in sympathetic neurons and release of chromogranin A fragments from sheep spleen. FEBS Lett (1992) 0.78

Chemical and biological characterization of thiol SAMs for neuronal cell attachment. Langmuir (2009) 0.78

Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1. Mol Med (1999) 0.77

Secretases as therapeutic targets for the treatment of Alzheimer's disease. Amyloid (2001) 0.76

Secretory vesicle-specific antibodies in the confocal study of exo-endocytosis dynamics. Methods (1999) 0.75

Ultrastructural localization of neuropeptide Y-immunoreactivity in the axonal reticulum elements, accumulating anterogradely in transected rat sciatic nerve. Brain Res (1993) 0.75

Conversion of angiotensin II into active fragments by an endosomal pathway in bovine adrenal medullary cells in primary culture. Endocrinology (1995) 0.75

Subcellular distribution and axonal transport of noradrenaline, dopamine-?-hydroxylase and neuropeptide Y in dog splenic nerve. Neurochem Int (1989) 0.75

Parkinsonian syndrome after cardiac arrest: radiological and neurochemical changes. Clin Neurol Neurosurg (1988) 0.75

New perspectives offered by combining a selective counterstaining (PTA) and postembedding lectin- or immuno-gold procedures. Prog Histochem Cytochem (1992) 0.75

Ultrastructural evidence for a separate, small synaptic vesicle (SSV) pathway in ligated bovine splenic nerves, incubated in vitro. Brain Res (1996) 0.75

Selective masking of M1-receptors in calf retina membranes by the venom of the marine snail Conus tessulatus. Neurochem Int (1993) 0.75

Peptide-functionalized microfabricated structures for improved on-chip neuronal adhesion. Conf Proc IEEE Eng Med Biol Soc (2008) 0.75