Published in Immunol Today on August 01, 1993
CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol (2004) 2.71
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo. Proc Natl Acad Sci U S A (1996) 1.49
An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function. J Cell Biol (1997) 1.46
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J Cell Biol (1996) 1.41
Melanoma x macrophage hybrids with enhanced metastatic potential. Clin Exp Metastasis (1998) 1.23
Role of hyaluronan in glioma invasion. Cell Adh Migr (2008) 1.16
Association between the rat homologue of CO-029, a metastasis-associated tetraspanin molecule and consumption coagulopathy. J Cell Biol (1998) 1.13
CD44 and the adhesion of neoplastic cells. Mol Pathol (1997) 1.12
Role of CD44 in the reaction of vascular smooth muscle cells to arterial wall injury. J Clin Invest (1996) 1.08
A cysteine residue located in the transmembrane domain of CD44 is important in binding of CD44 to hyaluronic acid. J Exp Med (1996) 0.99
Role of VEGF and CD44v6 in differentiating benign from malignant ascites. World J Gastroenterol (2003) 0.95
In vitro selection of exonic splicing enhancer sequences: identification of novel CD44 enhancers. Nucleic Acids Res (2001) 0.94
Two different functions for CD44 proteins in human myelopoiesis. J Clin Invest (1998) 0.91
Clinical significance of pAKT and CD44v6 overexpression with breast cancer. J Cancer Res Clin Oncol (2010) 0.91
Alterations of high endothelial venules in primary and metastatic tumors are correlated with lymph node metastasis of oral and pharyngeal carcinoma. Cancer Biol Ther (2013) 0.91
Serum levels of soluble CD44 variant isoforms are elevated in rheumatoid arthritis. Rheumatol Int (1997) 0.91
CD44 is not required for poliovirus replication. J Virol (1997) 0.88
Effect of cell fusion on metastatic ability of mouse hepatocarcinoma cell lines. World J Gastroenterol (1999) 0.88
CD44 isoform expression follows two alternative splicing pathways in breast tissue. Am J Pathol (1998) 0.86
CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells. Front Immunol (2015) 0.84
Expression of CD44 by rhabdomyosarcoma: a new prognostic marker? Br J Cancer (1999) 0.84
Multisite and bidirectional exonic splicing enhancer in CD44 alternative exon v3. RNA (2007) 0.83
Differential expression of CD44v6 in metastases of intestinal and diffuse types of gastric carcinoma. J Clin Pathol (1998) 0.83
CD44 isoforms containing exons V6 and V7 are differentially expressed on mitogenically stimulated normal and Epstein-Barr virus-transformed human B cells. Immunology (1995) 0.81
Modulation of superantigen-induced T-cell deletion by antibody anti-Pgp-1 (CD44). Immunology (1996) 0.80
CD44v6 expression in patients with stage II or stage III sporadic colorectal cancer is superior to CD44 expression for predicting progression. Int J Clin Exp Pathol (2015) 0.80
Identification of specific chondroitin sulfate species in cutaneous autoimmune disease. J Histochem Cytochem (2011) 0.79
Expression of A and H blood-group and of CD44 antigens during chemical rat colonic carcinogenesis. Glycoconj J (1997) 0.78
Expression and clinical significance of CD44V5 and CD44V6 in resectable colorectal cancer. J Cancer Res Clin Oncol (2004) 0.77
Histomolecular Structural Aspects of High Endothelial Vessels in Lymph Node and Its Significance in Oral Cancer and Metastasis. N Am J Med Sci (2015) 0.77
CD44v3 and v6 variant isoform expression correlates with poor prognosis in early-stage vulvar cancer. Br J Cancer (1998) 0.75
CD26-positive/CD326-negative circulating cancer cells as prognostic markers for colorectal cancer recurrence. Oncol Lett (2014) 0.75
CD 44 exon v6 as a predictor of lymphatic metastases in cervical carcinoma--an immunocytochemical study of 94 cases. Arch Gynecol Obstet (1995) 0.75
Rapid and reliable detection of CD44 variants in gastric carcinoma using a nested reverse transcription-polymerase chain reaction. Oncol Lett (2015) 0.75
Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion. Oncotarget (2016) 0.75
Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood (1994) 9.10
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell (1991) 7.29
Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell (1990) 6.56
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci U S A (1993) 4.97
Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters. Cell (1988) 4.13
Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. Am J Pathol (1999) 4.04
Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. Lancet (1994) 3.69
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. Genes Dev (2001) 3.65
Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene. Proc Natl Acad Sci U S A (1983) 3.42
CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet (1995) 3.07
Participation in normal immune responses of a metastasis-inducing splice variant of CD44. Science (1992) 3.05
CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol (2004) 2.71
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid. Oncogene (2001) 2.67
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J (1994) 2.58
Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties. Proc Natl Acad Sci U S A (1985) 2.47
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res (1993) 2.39
Autoregulation of fos: the dyad symmetry element as the major target of repression. EMBO J (1989) 2.37
CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines. Cancer Res (1991) 2.36
Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. J Immunol (1994) 2.11
A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps. J Cell Biol (1993) 2.06
Prevention of tumor metastasis formation by anti-variant CD44. J Exp Med (1993) 2.03
Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator. EMBO J (1998) 1.93
DNA sequences outside the receptor-binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones. EMBO J (1988) 1.93
Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion. Immunity (2001) 1.90
Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA. J Cell Biol (1992) 1.89
High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452. Am J Pathol (1988) 1.86
Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway. EMBO J (2001) 1.83
Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression. Curr Opin Cell Biol (1994) 1.79
The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription. Oncogene (1989) 1.78
Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44. J Exp Med (1993) 1.77
In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase. Proc Natl Acad Sci U S A (1975) 1.76
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth. Genes Dev (1998) 1.73
Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J (1992) 1.72
Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa. Cancer Res (1993) 1.68
Splicing choice from ten variant exons establishes CD44 variability. Nucleic Acids Res (1993) 1.68
Allosuppressor and allohelper T cells in acute and chronic graft-vs.-host disease. II. F1 recipients carrying mutations at H-2K and/or I-A. J Exp Med (1983) 1.66
The VLA-4/VCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium. J Immunol (1991) 1.63
Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met. J Biol Chem (1999) 1.58
Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA-1 pathway. J Immunol (1990) 1.58
Interdomain binding mediates tumor growth suppression by the NF2 gene product. Oncogene (1997) 1.55
Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines. Br J Cancer (2004) 1.54
Protein kinase induction in Escherichia coli by bacteriophage T7. Proc Natl Acad Sci U S A (1974) 1.54
DNA damage-induced gene expression: signal transduction and relation to growth factor signaling. Rev Physiol Biochem Pharmacol (1992) 1.52
CD44 acts both as a growth- and invasiveness-promoting molecule and as a tumor-suppressing cofactor. Ann N Y Acad Sci (2000) 1.52
Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy. J Virol (1998) 1.52
Adhesion molecules in the prognosis of diffuse large-cell lymphoma: expression of a lymphocyte homing receptor (CD44), LFA-1 (CD11a/18), and ICAM-1 (CD54). Leukemia (1990) 1.48
Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation. Cell Death Differ (2005) 1.46
An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function. J Cell Biol (1997) 1.46
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J Cell Biol (1996) 1.41
Loss of Ep-CAM (CO17-1A) expression predicts survival in patients with gastric cancer. Br J Cancer (2005) 1.38
The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma. Leukemia (2003) 1.37
Ultraviolet-radiation induced c-jun gene transcription: two AP-1 like binding sites mediate the response. Photochem Photobiol (1992) 1.37
Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization. Br J Cancer (2001) 1.34
Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7). J Exp Med (2000) 1.31
Dendritic cells and scavenger macrophages in chronic inflammatory bowel disease. Gut (1989) 1.29
Purification and properties of DNA-dependent RNA polymerases from yeast. Eur J Biochem (1972) 1.28
The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior. Cancer Res (1993) 1.28
A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells. Cancer Res (1993) 1.26
Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis. Gut (1995) 1.26
Heterogeneous ribonucleoprotein A1 is part of an exon-specific splice-silencing complex controlled by oncogenic signaling pathways. J Biol Chem (2000) 1.23
Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells. Virology (1985) 1.23
Comparison of immunohistochemistry and RT-PCR for detection of CD44v-expression, a new prognostic factor in human breast cancer. Int J Cancer (1995) 1.20
Dendritic cells and high endothelial venules in the rheumatoid synovial membrane. J Rheumatol (1990) 1.20
Surface protein expression and messenger RNA-splicing analysis of CD44 in uterine cervical cancer and normal cervical epithelium. Cancer Res (1994) 1.19
E. coli membranes become permeable to ions following T7-virus-infection. Mol Gen Genet (1976) 1.18
Antigenic differences between metastatic and nonmetastatic BSp73 rat tumor variants characterized by monoclonal antibodies. Cancer Res (1989) 1.18
Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family. Neurosci Lett (1989) 1.17
Characterization of BSp73, a spontaneous rat tumor and its in vivo selected variants showing different metastasizing capacities. Invasion Metastasis (1983) 1.17
High incidence of Kaposi sarcoma-associated herpesvirus infection in HIV-related solid immunoblastic/plasmablastic diffuse large B-cell lymphoma. Leukemia (2005) 1.16
Control of gene expression in bacteriophage T7: transcriptional controls. Mol Gen Genet (1974) 1.16
Trans-acting factors regulate the expression of CD44 splice variants. EMBO J (1996) 1.15
Signaling through CD44 is mediated by tyrosine kinases. Association with p56lck in T lymphocytes. J Biol Chem (1996) 1.14
Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway. J Exp Med (1997) 1.13
CD44 expression and regulation during mammary gland development and function. J Cell Sci (2000) 1.13
Association between the rat homologue of CO-029, a metastasis-associated tetraspanin molecule and consumption coagulopathy. J Cell Biol (1998) 1.13
High prevalence of oncogenic MYD88 and CD79B mutations in diffuse large B-cell lymphomas presenting at immune-privileged sites. Blood Cancer J (2013) 1.13
Transcription initiation of transfected mouse mammary tumor virus LTR DNA is regulated by glucocorticoid hormones. Nucleic Acids Res (1983) 1.13
CD70 represents the human ligand for CD27. Int Immunol (1994) 1.12
Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancer. Am J Pathol (2000) 1.12
Retardation of metastatic tumor growth after immunization with metastasis-specific monoclonal antibodies. Int J Cancer (1990) 1.11
Cell adhesion receptors in lymphoma dissemination. Blood (2000) 1.11
Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells. Cancer Res (1996) 1.11
Involvement of CD44 in cytoskeleton rearrangement and raft reorganization in T cells. J Cell Sci (2001) 1.10
Requirement for CD44 in proliferation and homing of hematopoietic precursor cells. J Leukoc Biol (1996) 1.10
Expression and release of CD27 in human B-cell malignancies. Blood (1993) 1.10
Interferon-gamma-deficient mice are resistant to the development of alopecia areata. Br J Dermatol (2006) 1.10