N Kartner

Author PubWeight™ 55.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell 1992 4.71
2 Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 1985 3.97
3 Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science 1983 3.88
4 Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 1985 3.59
5 Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP. EMBO J 1994 2.93
6 Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites. J Biol Chem 1993 2.85
7 The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells. J Biol Chem 1993 2.65
8 Limited proteolysis as a probe for arrested conformational maturation of delta F508 CFTR. Nat Struct Biol 1998 2.49
9 Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance. J Clin Oncol 1985 2.12
10 DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression. Mol Cell Biol 1982 2.03
11 Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene. J Biol Chem 1991 1.86
12 Multidrug resistance. Cancer Surv 1986 1.75
13 Multidrug-resistance phenotype in Chinese hamster ovary cells. Cancer Treat Rep 1983 1.72
14 P-glycoprotein in human sarcoma: evidence for multidrug resistance. J Clin Oncol 1987 1.64
15 Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein. Cancer Res 1983 1.53
16 The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH. J Biol Chem 1992 1.38
17 C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation. J Biol Chem 1999 1.32
18 COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments. J Cell Biol 2001 1.32
19 Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation. Biochem J 1997 1.26
20 cAMP-inducible chloride conductance in mouse fibroblast lines stably expressing the human cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A 1991 1.23
21 Regulation of CFTR expression and function during differentiation of intestinal epithelial cells. EMBO J 1992 1.18
22 Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells. Biochem J 1997 1.05
23 Isolation of plasma membranes from human skin fibroblasts. J Membr Biol 1977 0.97
24 Lectin-induced inhibition of plasma membrane 5'-nucleotidase: sensitivity of purified enzyme. Biochem Biophys Res Commun 1977 0.92
25 Expression of hamster P-glycoprotein and multidrug resistance in DNA-mediated transformants of mouse LTA cells. Mol Cell Biol 1987 0.89
26 Multidrug resistance. Breast Cancer Res Treat 1984 0.88
27 Altered plasma membrane ultrastructure in multidrug-resistant cells. Biochim Biophys Acta 1988 0.88
28 Induction of expression of the cystic fibrosis transmembrane conductance regulator. J Biol Chem 1992 0.86
29 Protein kinase C mediates down-regulation of cystic fibrosis transmembrane conductance regulator levels in epithelial cells. J Biol Chem 1993 0.84
30 Heterologous expression systems for study of cystic fibrosis transmembrane conductance regulator. Methods Enzymol 1998 0.83
31 Nature of the lectin-induced activation of plasma membrane Mg2+ATPase. J Biol Chem 1977 0.80
32 Expression of cell surface P-glycoprotein by an adriamycin-resistant murine fibrosarcoma. Cancer Chemother Pharmacol 1984 0.75