Flux, coupling, and selectivity in ionic channels of one conformation.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMC 1225775)

Published in Biophys J on August 01, 1993

Authors

D P Chen1, R S Eisenberg

Author Affiliations

1: Department of Physiology, Rush Medical College, Chicago, Illinois 60612.

Articles citing this

A lattice relaxation algorithm for three-dimensional Poisson-Nernst-Planck theory with application to ion transport through the gramicidin A channel. Biophys J (1999) 2.49

Permeation through an open channel: Poisson-Nernst-Planck theory of a synthetic ionic channel. Biophys J (1997) 2.29

A multi-substrate single-file model for ion-coupled transporters. Biophys J (1996) 1.57

Anomalous mole fraction effect, electrostatics, and binding in ionic channels. Biophys J (1998) 1.54

Electrostatics and the ion selectivity of ligand-gated channels. Biophys J (1998) 1.53

Theory for polymer analysis using nanopore-based single-molecule mass spectrometry. Proc Natl Acad Sci U S A (2010) 1.46

Conductance and permeability of the residual state of connexin43 gap junction channels. J Gen Physiol (2002) 1.41

Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels. Biophys J (1999) 1.38

Permeation through the calcium release channel of cardiac muscle. Biophys J (1997) 1.24

Sodium in gramicidin: an example of a permion. Biophys J (1995) 1.22

Charge selectivity of the designed uncharged peptide ion channel Ac-(LSSLLSL)3-CONH2. Biophys J (1995) 1.21

The role of the dielectric barrier in narrow biological channels: a novel composite approach to modeling single-channel currents. Biophys J (2003) 1.13

Selectivity and permeation in calcium release channel of cardiac muscle: alkali metal ions. Biophys J (1999) 1.09

(In)validity of the constant field and constant currents assumptions in theories of ion transport. Biophys J (1999) 1.03

Modeling and simulation of ion channels. Chem Rev (2012) 1.02

Geometry-induced asymmetric diffusion. Proc Natl Acad Sci U S A (2007) 0.97

Hydrodynamic model of temperature change in open ionic channels. Biophys J (1995) 0.97

Voltage-sensing and substate rectification: moving parts of connexin channels. J Gen Physiol (2002) 0.94

Nonlinear and asymmetric open channel characteristics of an ion-selective porin in planar membranes. Biophys J (1998) 0.85

Hemichannel composition and electrical synaptic transmission: molecular diversity and its implications for electrical rectification. Front Cell Neurosci (2014) 0.83

Mechanism of verapamil block of a neuronal delayed rectifier K channel: active form of the blocker and location of its binding domain. Br J Pharmacol (1999) 0.83

Structure-function study on a de novo synthetic hydrophobic ion channel. Biophys J (1999) 0.81

Auxin-driven patterning with unidirectional fluxes. J Exp Bot (2015) 0.80

Transport properties of single-file pores with two conformational states. Biophys J (1994) 0.78

Cation Selectivity in Biological Cation Channels Using Experimental Structural Information and Statistical Mechanical Simulation. PLoS One (2015) 0.75

Articles cited by this

A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol (1952) 160.83

The effect of sodium ions on the electrical activity of giant axon of the squid. J Physiol (1949) 149.79

The potassium permeability of a giant nerve fibre. J Physiol (1955) 27.53

Active transport of cations in giant axons from Sepia and Loligo. J Physiol (1955) 17.34

Ionic movements and electrical activity in giant nerve fibres. Proc R Soc Lond B Biol Sci (1958) 7.46

The electrostatic properties of membranes. Annu Rev Biophys Biophys Chem (1989) 5.37

Open-state substructure of single chloride channels from Torpedo electroplax. Philos Trans R Soc Lond B Biol Sci (1982) 5.26

Molecular architecture and electrostatic properties of a bacterial porin. Science (1991) 4.27

Nonlinear electrical effects in lipid bilayer membranes. I. Ion injection. Biophys J (1969) 3.90

Potassium movements in washed erythrocytes. J Physiol (1955) 3.61

Open-state substructure of inwardly rectifying potassium channels revealed by magnesium block in guinea-pig heart cells. J Physiol (1988) 3.29

Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations. Biophys J (1986) 3.19

Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step. Biophys J (1983) 3.15

Ion movement through gramicidin A channels. Interfacial polarization effects on single-channel current measurements. Biophys J (1983) 2.87

Molecular determinants of channel function. Physiol Rev (1992) 2.84

Steady-state coupling of ion-channel conformations to a transmembrane ion gradient. Science (1990) 2.80

Sodium permeability in toad nerve and in squid nerve. J Physiol (1960) 2.75

The role of the electrochemical gradient in determining potassium fluxes in frog striated muscle. J Gen Physiol (1968) 2.72

Transport proteins in bacteria: common themes in their design. Science (1992) 2.14

Potassium flux ratio in voltage-clamped squid giant axons. J Gen Physiol (1980) 2.05

Asymmetry in the mechanism for anion exchange in human red blood cell membranes. Evidence for reciprocating sites that react with one transported anion at a time. J Gen Physiol (1979) 2.04

Cellular transport mechanisms. Annu Rev Biochem (1978) 1.94

The three-dimensional structure of porin from Rhodobacter capsulatus at 3 A resolution. FEBS Lett (1990) 1.92

Surmounting barriers in ionic channels. Q Rev Biophys (1988) 1.47

Electrodiffusion of ions approaching the mouth of a conducting membrane channel. Biophys J (1988) 1.34

Sodium flux ratio in voltage-clamped squid giant axons. J Gen Physiol (1981) 1.33

Occluded cations in active transport. Annu Rev Biochem (1990) 1.24

Rapid release of 42K or 86Rb from two distinct transport sites on the Na,K-pump in the presence of Pi or vanadate. J Biol Chem (1987) 1.24

Constant fields and constant gradients in open ionic channels. Biophys J (1992) 1.23

Single-file diffusion through the Ca2+-activated K+ channel of human red cells. J Membr Biol (1985) 1.17

Rapid release of 42K and 86Rb from an occluded state of the Na,K-pump in the presence of ATP or ADP. J Biol Chem (1987) 1.13

Unidirectional flux ratio for potassium ions in depolarized frog skeletal muscle. Am J Physiol (1981) 1.06

Flux ratio theorems for nonstationary membrane transport with temporary capture of tracer. J Theor Biol (1986) 0.83

A calcium conducting channel akin to a calcium pump. J Membr Biol (1992) 0.83

Pump and exchanger mechanisms in a model of smooth muscle. Biophys Chem (1993) 0.82

Articles by these authors

Can patents deter innovation? The anticommons in biomedical research. Science (1998) 9.35

Capacitance of the surface and transverse tubular membrane of frog sartorius muscle fibers. J Gen Physiol (1969) 5.50

Ionic conductances of the surface and transverse tubular membranes of frog sartorius fibers. J Gen Physiol (1969) 5.45

Action potentials without contraction in frog skeletal muscle fibers with disrupted transverse tubules. Science (1967) 4.16

Action potentials, afterpotentials, and excitation-contraction coupling in frog sartorius fibers without transverse tubules. J Gen Physiol (1969) 3.86

Frog skeletal muscle fibers: changes in electrical properties after disruption of transverse tubular system. Science (1967) 3.76

Selective disruption of the sarcotubular system in frog sartorius muscle. A quantitative study with exogenous peroxidase as a marker. J Cell Biol (1968) 3.61

Impedance of frog skeletal muscle fibers in various solutions. J Gen Physiol (1974) 3.19

The maintenance of resting potentials in glycerol-treated muscle fibres. J Physiol (1971) 2.78

The role of the electrochemical gradient in determining potassium fluxes in frog striated muscle. J Gen Physiol (1968) 2.72

The spatial variation of membrane potential near a small source of current in a spherical cell. J Gen Physiol (1970) 2.70

Electrical properties of spherical syncytia. Biophys J (1979) 2.12

Diffusion theory and discrete rate constants in ion permeation. J Membr Biol (1988) 2.05

The equivalent circuit of single crab muscle fibers as determined by impedance measurements with intracellular electrodes. J Gen Physiol (1967) 1.97

Electrical properties of frog skeletal muscle fibers interpreted with a mesh model of the tubular system. Biophys J (1977) 1.88

The T-SR junction in contracting single skeletal muscle fibers. J Gen Physiol (1982) 1.74

Paralysis of frog skeletal muscle fibres by the calcium antagonist D-600. J Physiol (1983) 1.71

Electrical models of excitation-contraction coupling and charge movement in skeletal muscle. J Gen Physiol (1980) 1.68

Measurement of the impedance of frog skeletal muscle fibers. Biophys J (1974) 1.62

Electrical properties of structural components of the crystalline lens. Biophys J (1979) 1.56

The interpretation of current-voltage relations recorded from a spherical cell with a single microelectrode. Biophys J (1972) 1.49

Surmounting barriers in ionic channels. Q Rev Biophys (1988) 1.47

A cation channel in frog lens epithelia responsive to pressure and calcium. J Membr Biol (1986) 1.44

Circuit models of the passive electrical properties of frog skeletal muscle fibers. J Gen Physiol (1974) 1.42

Charge movement in skeletal muscle fibers paralyzed by the calcium-entry blocker D600. Proc Natl Acad Sci U S A (1984) 1.42

Current-voltage relationships in the crystalline lens. J Physiol (1976) 1.41

The lens as a nonuniform spherical syncytium. Biophys J (1981) 1.40

Derivation of Poisson and Nernst-Planck equations in a bath and channel from a molecular model. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 1.39

The role of the electrochemical gradient in determining potassium fluxes in frog striated muscle. J Gen Physiol (1968) 1.30

Constant fields and constant gradients in open ionic channels. Biophys J (1992) 1.23

Longitudinal impedance of skinned frog muscle fibers. J Gen Physiol (1974) 1.21

The capacitance of skeletal muscle fibers in solutions of low ionic strength. J Gen Physiol (1972) 1.16

Interpretation of some microelectrode measurements of electrical properties of cells. Annu Rev Biophys Bioeng (1973) 1.08

Longitudinal impedance of single frog muscle fibers. J Gen Physiol (1975) 1.03

The effect of 2-4 dinitrophenol on cell to cell communication in the frog lens. Exp Eye Res (1982) 1.03

Ionic channels in ocular epithelia. Ion Channels (1988) 1.02

Perfusing pipettes. Pflugers Arch (1990) 1.01

Structural analysis of electrical properties of cells and tissues. Crit Rev Bioeng (1980) 1.01

Dielectric boundary force and its crucial role in gramicidin. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 1.00

A theoretical analysis of the capacitance of muscle fibers using a distributed model of the tubular system. J Gen Physiol (1972) 0.99

Measurement, modeling, and analysis of the linear electrical properties of cells. Ann N Y Acad Sci (1977) 0.98

Hydrodynamic model of temperature change in open ionic channels. Biophys J (1995) 0.97

Electrical properties of sheep Purkinje strands. Electrical and chemical potentials in the clefts. Biophys J (1983) 0.95

The radial variation of potential in the transverse tubular system of skeletal muscle. J Gen Physiol (1971) 0.92

Calcium influx in contracting and paralyzed frog twitch muscle fibers. J Gen Physiol (1985) 0.91

Computing numerically the access resistance of a pore. Eur Biophys J (2005) 0.89

Transverse tubular system in glycerol-treated skeletal muscle. Science (1968) 0.89

K+-selective channel from sarcoplasmic reticulum of split lobster muscle fibers. J Gen Physiol (1989) 0.86

Saturation of conductance in single ion channels: the blocking effect of the near reaction field. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.85

Singular perturbation analysis of the steady-state Poisson-Nernst-Planck system: Applications to ion channels. Eur J Appl Math (2008) 0.84

Physiological role of the membranes and extracellular space with the ocular lens. Exp Eye Res (1982) 0.84

A calcium conducting channel akin to a calcium pump. J Membr Biol (1992) 0.83

The effects of the antibiotics gramicidin A, amphotericin B, and nystatin on the electrical properties of frog skeletal muscle. Biochim Biophys Acta (1973) 0.83

Perfusing patch pipettes. Methods Enzymol (1992) 0.81

Origins of open-channel noise in the large potassium channel of sarcoplasmic reticulum. J Gen Physiol (1994) 0.81

Middle lobe syndrome secondary to allergic bronchopulmonary aspergillosis. Ann Allergy (1980) 0.80

Electrical properties of the myotendon region of frog twitch muscle fibers measured in the frequency domain. Biophys J (1985) 0.80

Self-consistent analytic solution for the current and the access resistance in open ion channels. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.80

Impedance measurements as estimators of the properties of the extracellular space. Ann N Y Acad Sci (1986) 0.77

Analytical diffusion models for membrane channels. Ion Channels (1990) 0.77

Modified Donnan potentials for ion transport through biological ion channels. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 0.76

Memoryless control of boundary concentrations of diffusing particles. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.76

Integrated electrodes on a silicon based ion channel measurement platform. Biosens Bioelectron (2007) 0.76

Nebulization of amphotericin B. Am Rev Respir Dis (1971) 0.76

Multi-ion conduction bands in a simple model of calcium ion channels. Phys Biol (2013) 0.75

Complexities in solution. Trends Biochem Sci (1990) 0.75

Progressive pulmonary insufficiency due to mineral oil. Calif Med (1966) 0.75

Hodgkin's disease first suggested by sputum cytology. Chest (1974) 0.75

Effects of respiratory conditions on sedation and pre-medication in dentistry. J South Calif Dent Assoc (1971) 0.75

Studies on intact sarcoplasmic reticulum: patch clamp recording and tension measurement in lobster split muscle fibers. Methods Enzymol (1992) 0.75

Prolonged carboxyhemoglobin clearance in a patient with Waldenström's macroglobulinemia. Am J Emerg Med (1987) 0.75

Electrophysiology. Science (1982) 0.75

A new airway for tracheal or esophageal insertion: description and field experience. Ann Emerg Med (1980) 0.75

Membranes, calcium, and coupling. Can J Physiol Pharmacol (1987) 0.75

Structural complexity, circuit models, and ion accumulation. Fed Proc (1980) 0.75

Look at biological systems through an engineer's eyes. Nature (2007) 0.75

Effects of respiratory conditions on sedation and premedication in dentistry. J Contra Costa Dent Soc (1971) 0.75

Expanding technologies and responsibilities for respiratory care medical directors and practitioners. Respir Ther (1986) 0.75