| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Alkaloids from dendrobatid frogs: structures of two omega-hydroxy congeners of 3-butyl-5-propylindolizidine and occurrence of 2,5-disubstituted pyrrolidines and a 2,6-disubstituted piperidine.
|
J Nat Prod
|
1986
|
1.61
|
|
2
|
Stereoselective formation of bromobenzene glutathione conjugates.
|
Chem Biol Interact
|
1982
|
1.08
|
|
3
|
Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution.
|
Mol Pharmacol
|
1988
|
1.07
|
|
4
|
Occurrence of skin alkaloids in non-dendrobatid frogs from Brazil (Bufonidae), Australia (Myobatrachidae) and Madagascar (Mantellinae).
|
Toxicon
|
1984
|
0.94
|
|
5
|
The occurrence of pristane and phytane in man and animals.
|
Biochim Biophys Acta
|
1967
|
0.93
|
|
6
|
Mutagenic perylenequinone metabolites of Alternaria alternata: altertoxins I, II, and III.
|
J Nat Prod
|
1987
|
0.90
|
|
7
|
(5Z,9Z)-3-alkyl-5-methylindolizidines fromSolenopsis (Diplorhoptrum) species.
|
J Chem Ecol
|
1984
|
0.89
|
|
8
|
3-(glutathion-S-yl)acetaminophen: a biliary metabolite of acetaminophen.
|
Drug Metab Dispos
|
1982
|
0.89
|
|
9
|
Structure of satratoxin H, a metabolite of Stachybotrys atra. Application of proton and carbon-13 nuclear magnetic resonance.
|
J Org Chem
|
1977
|
0.88
|
|
10
|
Reductive-oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P-450.
|
Mol Pharmacol
|
1984
|
0.87
|
|
11
|
The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A.
|
J Antibiot (Tokyo)
|
1982
|
0.86
|
|
12
|
Artemisinin: an endoperoxidic antimalarial from Artemisia annua L.
|
Fortschr Chem Org Naturst
|
1997
|
0.84
|
|
13
|
13C nuclear magnetic resonance spectroscopy of native and recombined lipoproteins.
|
Proc Natl Acad Sci U S A
|
1974
|
0.84
|
|
14
|
Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac.
|
Chem Res Toxicol
|
1993
|
0.83
|
|
15
|
The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride.
|
Drug Metab Dispos
|
1981
|
0.82
|
|
16
|
Characterization by NMR of the heme-myoglobin adduct formed during the reductive metabolism of BrCCl3. Covalent bonding of the proximal histidine to the ring I vinyl group.
|
J Biol Chem
|
1991
|
0.82
|
|
17
|
2-Bromo-(diglutathion-S-yl)hydroquinone nephrotoxicity: physiological, biochemical, and electrochemical determinants.
|
Mol Pharmacol
|
1988
|
0.82
|
|
18
|
Glutathione conjugates of 2-bromohydroquinone are nephrotoxic.
|
Drug Metab Dispos
|
1985
|
0.81
|
|
19
|
Hydrogen peroxide-mediated alteration of the heme prosthetic group of metmyoglobin to an iron chlorin product: evidence for a novel oxidative pathway.
|
Proc Natl Acad Sci U S A
|
1997
|
0.80
|
|
20
|
Nephrotoxicity of chloroform: metabolism to phosgene by the mouse kidney.
|
Toxicol Appl Pharmacol
|
1984
|
0.80
|
|
21
|
Accumulation of oxygenated steryl esters in Wolman's disease.
|
J Lipid Res
|
1975
|
0.80
|
|
22
|
The structure of two isoflavones from the Abyssinian Berebera tree.
|
J Org Chem
|
1967
|
0.80
|
|
23
|
Oxidative cyclization, 1,4-benzothiazine formation and dimerization of 2-bromo-3-(glutathion-S-yl)hydroquinone.
|
Mol Pharmacol
|
1990
|
0.78
|
|
24
|
The mass spectra of pseudoguaianolides related to helenalin.
|
J Org Chem
|
1969
|
0.78
|
|
25
|
Metasternal gland secretion of the locust tree borer, Megacyllene robiniae (Coleoptera: Cerambycidae).
|
Comp Biochem Physiol B
|
1988
|
0.78
|
|
26
|
Formation of nontoxic reactive metabolites of p-bromophenol. Identification of a new glutathione conjugate.
|
Drug Metab Dispos
|
1984
|
0.77
|
|
27
|
Differences in the localization and extent of the renal proximal tubular necrosis caused by mercapturic acid and glutathione conjugates of 1,4-naphthoquinone and menadione.
|
Toxicol Appl Pharmacol
|
1990
|
0.77
|
|
28
|
Metabolism of alpha-naphthoflavone and beta-naphthoflavone by rat liver microsomes and highly purified reconstituted cytochrome P-450 systems.
|
J Biol Chem
|
1983
|
0.76
|
|
29
|
Two-dimensional J-resolved nuclear magnetic resonance spectral study of two bromobenzene glutathione conjugates.
|
Environ Health Perspect
|
1985
|
0.75
|
|
30
|
Studies on the Chemical Constituents of Premna fulva.
|
Planta Med
|
1991
|
0.75
|
|
31
|
Carbon-13 nuclear magnetic resonance studies of spironolactone and several related steroids.
|
Steroids
|
1980
|
0.75
|
|
32
|
Inactivation of horseradish peroxidase by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine.
|
Chem Res Toxicol
|
1995
|
0.75
|
|
33
|
Structural investigations of natural products by newer methods of NMR spectroscopy.
|
Fortschr Chem Org Naturst
|
1975
|
0.75
|
|
34
|
The use of stable isotopes to identify reactive metabolites and target macromolecules associated with toxicities of halogenated hydrocarbon compounds.
|
Xenobiotica
|
1992
|
0.75
|
|
35
|
Synthesis and nephrotoxicity of 6-bromo-2,5-dihydroxy-thiophenol.
|
Mol Pharmacol
|
1988
|
0.75
|
|
36
|
Structure of the novel heme adduct formed during the reaction of human hemoglobin with BrCCl3 in red cell lysates.
|
J Biol Chem
|
1994
|
0.75
|
|
37
|
Peyote alkaloids. IV. Structure of peyonine, novel beta-phenethylpyrrole from Lophophora williamsii.
|
J Pharm Sci
|
1968
|
0.75
|
|
38
|
Oxime formation in the reduction of a steroid nitroölefin.
|
Steroids
|
1966
|
0.75
|