An evolutionary conserved COUP-TF binding element in a neural-specific gene and COUP-TF expression patterns support a major role for COUP-TF in neural development.

PubWeight™: 0.92‹?›

🔗 View Article (PMID 7708064)

Published in Mol Endocrinol on December 01, 1994

Authors

X P Lu1, G Salbert, M Pfahl

Author Affiliations

1: La Jolla Cancer Research Foundation, California 92037.

Articles citing this

Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. PLoS Genet (2007) 1.52

COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Mol Cell Biol (1999) 1.28

Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells. Mol Cell Biol (2000) 1.17

Positive regulation of the vHNF1 promoter by the orphan receptors COUP-TF1/Ear3 and COUP-TFII/Arp1. Mol Cell Biol (1996) 1.07

Functional domains of the human orphan receptor ARP-1/COUP-TFII involved in active repression and transrepression. Mol Cell Biol (1997) 1.03

The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci (2009) 1.00

Transcriptional activation by the orphan nuclear receptor ARP-1. Nucleic Acids Res (1995) 0.98

COUP-TF II homodimers are formed in preference to heterodimers with RXR alpha or TR beta in intact cells. Nucleic Acids Res (1995) 0.96

Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2. J Biol Chem (1999) 0.95

The nuclear orphan receptors COUP-TF and ARP-1 positively regulate the trout estrogen receptor gene through enhancing autoregulation. Mol Cell Biol (1997) 0.92

Nuclear receptors in bone physiology and diseases. Physiol Rev (2013) 0.86

COUP-TFs and eye development. Biochim Biophys Acta (2014) 0.77

Articles by these authors

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature (1992) 4.44

How lac repressor binds to DNA. Nature (1972) 3.72

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature (1992) 3.39

A new retinoic acid receptor identified from a hepatocellular carcinoma. Nature (1988) 3.33

"Second" and "third operator" of the lac operon: an investigation of their role in the regulatory mechanism. J Mol Biol (1979) 2.56

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity. Nature (1989) 2.23

A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library. Science (1987) 2.21

COUP orphan receptors are negative regulators of retinoic acid response pathways. Mol Cell Biol (1992) 1.94

An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element. J Biol Chem (1996) 1.92

Retinoids selective for retinoid X receptor response pathways. Science (1992) 1.91

A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol (1994) 1.86

Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region. Cell (1982) 1.75

Repressors. Adv Protein Chem (1976) 1.51

Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol (1991) 1.44

A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter. Mol Endocrinol (1990) 1.43

Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities. Mol Cell Biol (1991) 1.41

A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature (1994) 1.31

Characteristics of tight binding repressors of the lac operon. J Mol Biol (1981) 1.29

Genetic analysis of the active sites of lac repressor. Genetics (1974) 1.27

DNA binding properties of glucocorticosteroid receptors bound to the steroid antagonist RU-486. EMBO J (1984) 1.27

Retinoic acid receptors and retinoid X receptor-alpha down-regulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity. Mol Endocrinol (1993) 1.24

Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching. Mol Cell Biol (1993) 1.22

Nuclear retinoic acid receptors: cloning, analysis, and function. Methods Enzymol (1990) 1.17

General features of steroid resistance on lymphoid cell lines. Mol Cell Endocrinol (1978) 1.16

The human estrogen receptor has transcriptional activator and repressor functions in the absence of ligand. New Biol (1990) 1.16

RAR gamma 2 expression is regulated through a retinoic acid response element embedded in Sp1 sites. Mol Cell Biol (1992) 1.15

Antagonism between retinoic acid receptors. Mol Cell Biol (1991) 1.14

lac Repressor-operator interaction. Analysis of the X86 repressor mutant. J Mol Biol (1976) 1.13

Genetic map of the lactose repressor gene (i) of Escherichia coli. Genetics (1972) 1.13

4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors. J Biol Chem (1996) 1.07

Correlation of glucocorticoid receptor binding sites on MMTV proviral DNA with hormone inducible transcription. Science (1983) 1.06

Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor. Mol Cell Biol (1994) 1.06

Effect of DNA denaturants on the lac repressor-operator interaction. Biochim Biophys Acta (1978) 1.05

Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation. Mol Cell Biol (1997) 1.04

A retinoic acid response element from the rat CRBPI promoter is activated by an RAR/RXR heterodimer. Biochem Biophys Res Commun (1992) 1.03

Inhibition of estrogen receptor activity by the tumor promoter 12-O-tetradeconylphorbol-13-acetate: a molecular analysis. Mol Endocrinol (1991) 1.02

Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities. Mol Endocrinol (1992) 1.02

TOR: a new orphan receptor expressed in the thymus that can modulate retinoid and thyroid hormone signals. Mol Endocrinol (1995) 1.01

Retinoic acid affects the expression of nuclear retinoic acid receptors in tissues of retinol-deficient rats. Proc Natl Acad Sci U S A (1991) 1.01

Interaction of glucocorticoid receptors from lymphoid cell lines with their nuclear acceptor sites. Mol Cell Endocrinol (1978) 0.99

Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo. Nat Med (1997) 0.99

DNA bending by retinoid X receptor-containing retinoid and thyroid hormone receptor complexes. Mol Cell Biol (1993) 0.98

Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity. J Med Chem (1995) 0.95

Hetero- and homodimeric receptors in thyroid hormone and vitamin A action. Receptor (1993) 0.94

Genomic organization of the retinoic acid receptor gamma gene. Nucleic Acids Res (1991) 0.93

A specific defect in the retinoic acid response associated with human lung cancer cell lines. Cancer Res (1994) 0.92

V-erbA requires auxiliary proteins for dominant negative activity. Oncogene (1993) 0.92

The nuclear orphan receptors COUP-TF and ARP-1 positively regulate the trout estrogen receptor gene through enhancing autoregulation. Mol Cell Biol (1997) 0.92

Ligand-binding domain of thyroid hormone receptors modulates DNA binding and determines their bifunctional roles. New Biol (1991) 0.92

A synthetic retinoid antagonist inhibits the human immunodeficiency virus type 1 promoter. Proc Natl Acad Sci U S A (1994) 0.91

DNA binding and dimerization determinants for thyroid hormone receptor alpha and its interaction with a nuclear protein. Mol Endocrinol (1991) 0.90

The LIM/homeodomain protein islet-1 modulates estrogen receptor functions. Mol Endocrinol (2000) 0.90

COUP-TFI (chicken ovalbumin upstream promoter-transcription factor I) regulates cell migration and axogenesis in differentiating P19 embryonal carcinoma cells. Mol Endocrinol (2000) 0.90

6'-substituted naphthalene-2-carboxylic acid analogs, a new class of retinoic acid receptor subtype-specific ligands. Biochem Biophys Res Commun (1991) 0.89

Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro. Blood (1996) 0.89

The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal. Mol Cell Biol (1996) 0.88

Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases. Cancer Res (2001) 0.88

Apoptosis induction and potent antiestrogen receptor-negative breast cancer activity in vivo by a retinoid antagonist. Cancer Res (1998) 0.88

Regulatory functions of a non-ligand-binding thyroid hormone receptor isoform. Cell Regul (1991) 0.88

Isolation of pseudorevertants of lac oc mutants: selection system for superoperator mutations. J Bacteriol (1976) 0.87

Identification of retinoids with nuclear receptor subtype-selective activities. Cancer Res (1991) 0.86

Analysis of steroid resistance in lymphoid cell hybrids. Somatic Cell Genet (1980) 0.86

Retinoic acid receptor gamma1 (RARgamma1) levels control RARbeta2 expression in SK-N-BE2(c) neuroblastoma cells and regulate a differentiation-apoptosis switch. Mol Cell Biol (1998) 0.84

Interaction of tight binding repressors with lac operators. An analysis by DNA-footprinting. J Mol Biol (1984) 0.84

The orphan receptor TAK1 acts as a repressor of RAR-, RXR- and T3R-mediated signaling pathways. Biochem Biophys Res Commun (1995) 0.84

A selective retinoid with high activity against an androgen-resistant prostate cancer cell type. Int J Cancer (1999) 0.83

Thyroid hormone receptors repress estrogen receptor activation of a TRE. Mol Endocrinol (1991) 0.83

Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity. J Med Chem (1993) 0.83

Monolayer and aggregate cultures of rainbow trout hepatocytes: long-term and stable liver-specific expression in aggregates. J Cell Sci (1993) 0.83

Tight-binding repressors of the lac operon: selection system and in vitro analysis. J Bacteriol (1979) 0.82

Thyroid hormone receptor homodimers can function as ligand-sensitive repressors. Mol Endocrinol (1995) 0.81

Potential role for retinoic acid receptor-gamma in the inhibition of breast cancer cells by selective retinoids and interferons. Cancer Res (1996) 0.80

Differential effects of all-trans and 13-cis-retinoic acid on mRNA levels of nuclear retinoic acid receptors in rat lung and liver. Biochem Biophys Res Commun (1991) 0.80

Similar ligand-induced conformational changes of thyroid hormone receptors regulate homo- and heterodimeric functions. J Biol Chem (1995) 0.80

Effects of nonylphenol on estrogen receptor conformation, transcriptional activity and sexual reversion in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol (2001) 0.79

Escape synthesis of beta-galactosidase in strains of Escherichia coli lysogenic for lambda cI-857-h-80-t-68-dlac. Mol Gen Genet (1969) 0.79

Serotonin and dopamine turnover in the female rainbow trout (Oncorhynchus mykiss) brain and pituitary: changes during the annual reproductive cycle. Gen Comp Endocrinol (1992) 0.78

Cooperation between the human estrogen receptor (ER) and MCF-7 cell-specific transcription factors elicits high activity of an estrogen-inducible enhancer from the trout ER gene promoter. Mol Endocrinol (1996) 0.78

Recombinant human retinoic acid receptor beta. Binding of synthetic retinoids and transcriptional activation. J Biol Chem (1994) 0.78

A novel class of retinoid antagonists and their mechanism of action. J Biol Chem (1996) 0.78

Coordinate expression of functionally distinct thyroid hormone receptor alpha isoforms during neonatal brain development. Mol Endocrinol (1991) 0.78

ET-1 expression and growth inhibition of prostate cancer cells: a retinoid target with novel specificity. Cancer Res (1998) 0.78

Mapping of I Gene mutations which lead to repressors with increased affinity for lac operator. J Mol Biol (1981) 0.77

Glucocorticoid hormone interactions with cloned proviral DNA of mouse mammary tumor virus. J Steroid Biochem (1984) 0.77

Interplay between liganded and orphan nuclear receptors controls reproductive pathways. Biochem Cell Biol (2000) 0.77

Variable responsiveness of hormone-inducible hybrid genes in different cell lines. Mol Endocrinol (1988) 0.77

Regulation of H1(0) gene expression by nuclear receptors through an unusual response element: implications for regulation of cell proliferation. DNA Cell Biol (1995) 0.77

A mutant lactose repressor with altered inducer and operator binding parameters. J Mol Biol (1985) 0.77

Retinoid actions and implications for prevention and therapy of oral cancer. Int J Oral Maxillofac Surg (1996) 0.76

Treatment of cervical intraepithelial neoplasia levels 2 and 3 with adapalene, a retinoid-related molecule. J Low Genit Tract Dis (2001) 0.76

Distribution of estrogen receptor-immunoreactive cells in the brain of the rainbow trout (Oncorhynchus mykiss). J Neuroendocrinol (1994) 0.76

Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function. Mol Endocrinol (1995) 0.76

Eukaryotic conditional expression system. Biotechniques (1999) 0.75

Molecular mechanisms of action for vitamin A-derived hormones. Prog Clin Biol Res (1994) 0.75