Tumors in Rubinstein-Taybi syndrome.

Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature (2011) 5.20

CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature (2011) 3.72

Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev (2000) 3.24

The sonic hedgehog-patched-gli pathway in human development and disease. Am J Hum Genet (2000) 2.42

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease. Am J Hum Genet (2005) 2.40

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci U S A (1997) 2.01

Congenital anomalies and childhood cancer in Great Britain. Am J Hum Genet (1997) 1.69

Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF. Mol Cell Biol (2003) 1.41

Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers. Mol Cell Biol (2000) 1.32

Rhabdomyosarcoma in adolescent and young adult patients: current perspectives. Adolesc Health Med Ther (2014) 1.28

Hypothesis: neoplasms in myotonic dystrophy. Cancer Causes Control (2009) 1.22

DNA sequencing of CREBBP demonstrates mutations in 56% of patients with Rubinstein-Taybi syndrome (RSTS) and in another patient with incomplete RSTS. Hum Genet (2005) 1.16

Rubinstein-Taybi syndrome: clinical features, genetic basis, diagnosis, and management. Ital J Pediatr (2015) 1.12

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease. Epigenomics (2012) 1.10

Rubinstein-taybi syndrome: a case report. Case Rep Dent (2012) 1.09

Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53. J Virol (2006) 1.07

Rubinstein-Taybi Syndrome: spectrum of CREBBP mutations in Italian patients. BMC Med Genet (2006) 1.06

Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1. Mol Cell Biol (2002) 1.03

Protein lysine acetylation by p300/CBP. Chem Rev (2015) 1.02

Rubinstein-taybi syndrome: a female patient with a de novo reciprocal translocation t(2; 16)(q36.3; p13.3) and dysgranulopoiesis. Clinics (Sao Paulo) (2010) 1.00

Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. Int J Oncol (2011) 1.00

Rubinstein-Taybi syndrome: Clinical profile of 11 patients and review of literature. Indian J Hum Genet (2012) 0.99

Is histone acetylation the most important physiological function for CBP and p300? Aging (Albany NY) (2012) 0.95

Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes. Epigenetics (2010) 0.94

The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway. Biochem J (2006) 0.91

KATs in cancer: functions and therapies. Oncogene (2015) 0.89

Regulation of ERK1 gene expression by coactivator proteins. Biochem J (2005) 0.87

Extracellular signals regulate rapid coactivator recruitment at AP-1 sites by altered phosphorylation of both CREB binding protein and c-jun. Mol Cell Biol (2008) 0.87

Epigenetic mechanisms of Rubinstein-Taybi syndrome. Neuromolecular Med (2014) 0.86

Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes. Nat Commun (2015) 0.86

A gain-of-function allele of cbp-1, the Caenorhabditis elegans ortholog of the mammalian CBP/p300 gene, causes an increase in histone acetyltransferase activity and antagonism of activated Ras. Mol Cell Biol (2005) 0.86

Epigenetics of neurological cancers. Future Oncol (2009) 0.85

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity? Toxicol Sci (2011) 0.85

Rhabdomyosarcomas: an overview on the experimental animal models. J Cell Mol Med (2012) 0.84

The importance of microsurgery in childhood meningioma: a case report. Childs Nerv Syst (2014) 0.84

Correlates of tumor development in patients with myotonic dystrophy. J Neurol (2012) 0.82

High frequency of copy number imbalances in Rubinstein-Taybi patients negative to CREBBP mutational analysis. Eur J Hum Genet (2010) 0.79

Rubinstein-Taybi syndrome with agenesis of corpus callosum. J Pediatr Neurosci (2015) 0.78

Pilomatrixomas in Rubinstein-Taybi syndrome. Am J Med Genet (1998) 0.78

Characterization of 14 novel deletions underlying Rubinstein-Taybi syndrome: an update of the CREBBP deletion repertoire. Hum Genet (2015) 0.78

Whole exome sequencing for a patient with Rubinstein-Taybi syndrome reveals de novo variants besides an overt CREBBP mutation. Int J Mol Sci (2015) 0.77

Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes. Sci Rep (2016) 0.76

Surgical treatment of scoliosis in Rubinstein-Taybi syndrome type 2: a case report. J Med Case Rep (2015) 0.75

Ultra-Rare Syndromes: The Example of Rubinstein-Taybi Syndrome. J Pediatr Genet (2015) 0.75

Rubinstein-Taybi Syndrome Associated with Pituitary Macroadenoma: A Case Report. Cureus (2017) 0.75

Acetyltransferases and tumour suppression. Breast Cancer Res (2000) 0.75

A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma. BMJ Case Rep (2014) 0.75

Diagnostic analysis of the Rubinstein-Taybi syndrome: five cosmids should be used for microdeletion detection and low number of protein truncating mutations. J Med Genet (2000) 1.26

Genotype-phenotype correlations in Rubinstein-Taybi syndrome. Am J Med Genet A (2008) 1.18

Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome. Am J Med Genet (2000) 1.04

Keloids and neoplasms in the Rubinstein-Taybi syndrome. Med Pediatr Oncol (1989) 1.01

Water intoxication secondary to feeding mismanagement. A preventable form of familial seizure disorder in infants. Am J Dis Child (1981) 0.97

Glaucoma and findings simulating glaucoma in the Rubinstein-Taybi syndrome. J Pediatr Ophthalmol Strabismus (1996) 0.83

Instability of the patellofemoral joint in Rubinstein-Taybi syndrome. J Pediatr Orthop (1998) 0.83

Surgical treatment of the thumb in the Rubinstein-Taybi syndrome. J Hand Surg Br (1987) 0.81

[Neuroophthalmologic characteristics of the wide "wide thumbs" syndrome of Rubinstein-Taybi. Apropos of an undetected case]. Rev Otoneuroophtalmol (1973) 0.76

Mental retardation, absence of patellae, and other malformations with chromosomal mosaicism. A follow-up report. J Pediatr (1968) 0.75

Letter: Fatherhood of the so-called Rubinstein-Taybi syndrome. Am J Dis Child (1974) 0.75