Published in J Clin Invest on June 01, 1995
Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS One (2012) 1.59
Involvement of serotonin and calcium channels in the intestinal fluid secretion evoked by bile salt and cholera toxin. Br J Pharmacol (1999) 0.97
Intestinal bile acid physiology and pathophysiology. World J Gastroenterol (2008) 0.95
Secretory diarrhoea: mechanisms and emerging therapies. Nat Rev Gastroenterol Hepatol (2015) 0.94
Enteric neurones modulate the colonic permeability response to luminal bile acids in rat colon in vivo. Gut (2004) 0.90
Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. Am J Physiol Cell Physiol (2013) 0.88
Esophageal visceral sensitivity to bile salts in patients with functional heartburn and in healthy control subjects. Dig Dis Sci (2005) 0.87
Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells. J Cell Mol Med (2009) 0.86
Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon. Dig Dis Sci (2001) 0.84
Ursodeoxycholic acid attenuates colonic epithelial secretory function. J Physiol (2013) 0.83
Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes. World J Gastrointest Pathophysiol (2010) 0.78
Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids. Front Nutr (2016) 0.78
Systemic phosphatidylcholine pretreatment protects canine esophageal mucosa during acute experimental biliary reflux. World J Gastroenterol (2006) 0.77
The Farnesoid X Receptor: Good for BAD. Cell Mol Gastroenterol Hepatol (2016) 0.76
The effect of biliary sphincterotomy on serum cholesterol level in postcholecystectomy patients: a pilot study. Can J Gastroenterol (2007) 0.75
Phospholipase C and src tyrosine kinases mediate neurotensin-stimulated Cl- secretion in rabbit proximal colon. Dig Dis Sci (2004) 0.75
The Effect of Deoxycholic Acid on Secretion and Motility in the Rat and Guinea Pig Large Intestine. J Neurogastroenterol Motil (2017) 0.75
Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man. J Clin Invest (1971) 4.18
Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride. Gastroenterology (1972) 2.73
Perfusion of the canine colon with unconjugated bile acids. Effect on water and electrolyte transport, morphology, and bile acid absorption. Gastroenterology (1970) 2.43
Unusual permeability properties of gastric gland cells. Nature (1994) 1.74
Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their first degree relatives. Gut (1994) 1.70
Intestinal permeability: functional assessment and significance. Clin Sci (Lond) (1992) 1.66
Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions. J Lipid Res (1992) 1.62
Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon. J Lab Clin Med (1979) 1.57
High pressure liquid chromatographic analysis of conjugated bile acids in human bile: simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids. J Lipid Res (1987) 1.51
Abnormal small intestinal permeability to sugars in patients with Crohn's disease of the terminal ileum and colon. Digestion (1983) 1.50
Bile salt alteration of colonic electrolyte transport: role of cyclic adenosine monophosphate. Gastroenterology (1975) 1.28
Transbilayer movement of bile acids in model membranes. Biochemistry (1987) 1.24
Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon. J Clin Invest (1973) 1.22
Cl- secretion induced by bile salts. A study of the mechanism of action based on a cultured colonic epithelial cell line. J Clin Invest (1989) 1.14
Factors in the mechanism of diarrhea in bile acid malabsorption: fecal pH--a key determinant. Gastroenterology (1981) 1.11
Immune-related intestinal Cl- secretion. I. Effect of histamine on the T84 cell line. Am J Physiol (1988) 1.09
Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84) J Clin Invest (1993) 1.09
Propranolol inhibits bile acid and fatty acid stimulation of cyclic AMP in human colon. Gastroenterology (1977) 1.07
Bile acid malabsorption and bile acid diarrhea in intestinal resection. Dig Dis Sci (1982) 1.06
Effect of ricinoleic acid and other laxatives on net water flux and prostaglandin E release by the rat colon. J Pharm Pharmacol (1979) 1.06
Ricinoleate and deoxycholate are calcium ionophores in jejunal brush border vesicles. J Membr Biol (1982) 1.04
Altered fecal bile acid pattern in patients with inflammatory bowel disease. Digestion (1986) 1.00
Activation of mast cells by bile acids. Gastroenterology (1991) 1.00
Dose-related effects of chenodeoxycholic acid in the rabbit colon. Dig Dis Sci (1980) 0.99
Franco-Belgian cooperative study of ursodeoxycholic acid in the medical dissolution of gallstones: a double-blind, randomized, dose-response study, and comparison with chenodeoxycholic acid. Hepatology (1984) 0.95
Role of prostaglandins in bile salt-induced changes in rat colonic structure and function. Clin Sci (Lond) (1981) 0.95
The importance of the enteric nervous system for the bile-salt-induced secretion in the small intestine of the rat. Scand J Gastroenterol (1983) 0.94
Structure of bile acids associated with secretion in the rat cecum. Gastroenterology (1979) 0.94
Effect of propranolol on ricinoleic acid- and deoxycholic acid-induced changes of intestinal electrolyte movement and mucosal permeability. Evidence against the importance of altered permeability in the production of fluid and electrolyte accumulation. Gastroenterology (1978) 0.86
Loss of absorptive capacity for sodium chloride as a cause of diarrhea following partial ileal and right colon resection. Dig Dis Sci (1989) 0.86
Dihydroxy bile salt-induced alterations in NaCl transport across the rabbit colon. Am J Physiol (1983) 0.85
Effect of ursodeoxycholic acid on intracellular pH in a bile duct epithelium-like cell line. Hepatology (1994) 0.83
Effects of chenodeoxy- and ursodeoxycholic acid on absorption, secretion and permeability in rat colon and small intestine. Digestion (1980) 0.83
Dihydroxy bile salt-induced secretion of rubidium ion across the rabbit distal colon. Am J Physiol (1987) 0.83
Effect of antihistamines on antigen-induced increase of rat tracheal mucous gel layer thickness. Int Arch Allergy Appl Immunol (1988) 0.81
Anticholinergic potency of diphenhydramine (Benadryl) measured against bethanechol in the gastric fistula dog. J Pharmacol Exp Ther (1983) 0.78
Dissolution of cholesterol gallstones by chenodeoxycholic acid. N Engl J Med (1972) 4.26
Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man. J Clin Invest (1971) 4.18
Organotypic slice cultures: a technique has come of age. Trends Neurosci (1997) 4.05
Miniature synaptic events maintain dendritic spines via AMPA receptor activation. Nat Neurosci (1999) 3.80
Breath test for altered bile-acid metabolism. Lancet (1971) 3.60
Detergent properties of bile salts: correlation with physiological function. Annu Rev Med (1967) 3.25
Letter: A simple calculation of the lithogenic index of bile: expressing biliary lipid composition on rectangular coordinates. Gastroenterology (1973) 3.09
Increased reflux of bile into the stomach in patients with gastric ulcer. Gastroenterology (1969) 2.86
The syndrome of ileal disease and the broken enterohepatic circulation: cholerheic enteropathy. Gastroenterology (1967) 2.81
Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride. Gastroenterology (1972) 2.73
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem (1998) 2.72
Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC). Gut (2003) 2.70
Paired-pulse facilitation and depression at unitary synapses in rat hippocampus: quantal fluctuation affects subsequent release. J Physiol (1996) 2.70
Long-term synaptic plasticity between pairs of individual CA3 pyramidal cells in rat hippocampal slice cultures. J Physiol (1998) 2.67
Sensitivity and specificity in tests of distal ileal function: prospective comparison of bile acid and vitamin B 12 absorption in ileal resection patients. Gastroenterology (1973) 2.42
Cholestyramine treatment of diarrhea associated with ileal resection. N Engl J Med (1969) 2.40
Acquired hyperoxaluria, nephrolithiasis, and intestinal disease. Description of a syndrome. N Engl J Med (1972) 2.21
Prospective comparison of indirect methods for detecting lactase deficiency. N Engl J Med (1975) 2.18
Action-potential propagation gated by an axonal I(A)-like K+ conductance in hippocampus. Nature (1997) 2.06
Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus. Neuron (1992) 2.06
Triolein breath test: a sensitive and specific test for fat malabsorption. Gastroenterology (1979) 1.98
Efficacy and specificity of chenodeoxycholic acid therapy for dissolving gallstones. N Engl J Med (1973) 1.98
Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion. Gastroenterology (1997) 1.95
Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology (1977) 1.92
Simultaneous measurements of total pancreatic, biliary, and gastric outputs in man using a perfusion technique. Gastroenterology (1970) 1.86
Monooctanoin, a dissolution agent for retained cholesterol bile duct stones: physical properties and clinical application. Gastroenterology (1980) 1.84
Radioimmunoassay of conjugated cholyl bile acids in serum. Gastroenterology (1973) 1.81
Temperature dependence of intrinsic membrane properties and synaptic potentials in hippocampal CA1 neurons in vitro. J Neurosci (1985) 1.80
Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: implications for the genesis of posttraumatic epilepsy. Nat Med (1997) 1.79
Effect of glycine-conjugated bile acids with and without lecithin on water and glucose absorption in perfused human jejunum. J Clin Invest (1973) 1.73
Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. J Clin Invest (1997) 1.68
Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. part I. Dig Dis Sci (1982) 1.67
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gastroenterology (1995) 1.66
The influence of bile salt structure on self-association in aqueous solutions. J Biol Chem (1983) 1.62
Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron (1997) 1.59
Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J Lipid Res (1984) 1.59
Dynamics of the enterohepatic circulation of bile acids. Postprandial serum concentrations of conjugates of cholic acid in health, cholecystectomized patients, and patients with bile acid malabsorption. N Engl J Med (1974) 1.58
A physicochemical approach to the intraluminal phase of fat absorption. Gastroenterology (1966) 1.57
Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon. J Lab Clin Med (1979) 1.57
Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinum toxin A and C, but not tetanus toxin. J Neurosci (1997) 1.55
Chemical treatment of stones in the biliary tree. Br J Surg (1986) 1.53
Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects. Mayo Clin Proc (1974) 1.53
Pancreozymin bioassay in man based on pancreatic enzyme secretion: potency of specific amino acids and other digestive products. J Clin Invest (1970) 1.51
High pressure liquid chromatographic analysis of conjugated bile acids in human bile: simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids. J Lipid Res (1987) 1.51
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. II. Glycine-conjugated dihydroxy bile acids. J Clin Invest (1972) 1.50
Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro. J Neurosci (1995) 1.50
Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons. Science (2001) 1.49
Sugar absorption by the biliary ductular epithelium of the rat: evidence for two transport systems. Gastroenterology (1992) 1.48
Absorption of cholesterol from a micellar solution: intestinal perfusion studies in man. J Clin Invest (1967) 1.46
Assay of urinary oxalate: six methodologies compared. Clin Chem (1983) 1.44
Mechanism of mu-opioid receptor-mediated presynaptic inhibition in the rat hippocampus in vitro. J Physiol (1993) 1.42
Assessment of activity in chronic active liver disease. Serum bile acids compared with conventional tests and histology. N Engl J Med (1974) 1.42
Bile acid malabsorption caused by ileal resection. Arch Intern Med (1972) 1.41
Biliary lipid output during three meals and an overnight fast. II. Effect of chenodeoxycholic acid treatment in gallstone subjects. Gut (1975) 1.41
The enterohepatic circulation of bile acids in man. Clin Gastroenterol (1977) 1.41
Asynchronous pre- and postsynaptic activity induces associative long-term depression in area CA1 of the rat hippocampus in vitro. Proc Natl Acad Sci U S A (1994) 1.41
Effect of replacement therapy with cholylsarcosine on fat malabsorption associated with severe bile acid malabsorption. Studies in dogs with ileal resection. Dig Dis Sci (1992) 1.39
Biliary lipid secretion in gallstone patients. Lancet (1973) 1.39
Maternal phenylketonuria: a continuing problem. Med J Aust (1999) 1.38
Physiology and pharmacology of unitary synaptic connections between pairs of cells in areas CA3 and CA1 of rat hippocampal slice cultures. J Neurophysiol (1995) 1.38
Long-term uncoupling of chloride secretion from intracellular calcium levels by Ins(3,4,5,6)P4. Nature (1994) 1.35
Retained biliary tract stones. Nonsurgical treatment with capmul 8210, a new cholesterol gallstone dissolution agent. Arch Surg (1981) 1.34
Plasma disappearance of radioactivity after intravenous injection of labeled bile acids in man. Gastroenterology (1975) 1.34
Disturbances in fat digestion induced by acidic jejunal pH due to gastric hypersecretion in man. Gastroenterology (1970) 1.33
Leptin acts as a mitogenic and antiapoptotic factor for colonic cancer cells. Br J Surg (2007) 1.32
Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). I. Chemical analysis and biological properties of PEG 400. Gastroenterology (1977) 1.29
Increased bacterial degradation of bile acids in cholecystectomized patients. Gastroenterology (1974) 1.27
Colonic absorption of unconjugated bile acids: perfusion studies in man. Dig Dis Sci (1979) 1.26
Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. Part II. Dig Dis Sci (1982) 1.26
Heterogeneity of synaptic plasticity at unitary CA3-CA1 and CA3-CA3 connections in rat hippocampal slice cultures. J Neurosci (1999) 1.25
Enzymatic measurement of choline-containing phospholipids in bile. J Lipid Res (1981) 1.24
Metabolism of lithocholate in healthy man. II. Enterohepatic circulation. Gastroenterology (1975) 1.22
Effect of oral chenodeoxycholic acid on bile acid kinetics and biliary lipid composition in women with cholelithiasis. J Clin Invest (1973) 1.22
Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion. J Biol Chem (1998) 1.20
Cooperative interactions in the induction of long-term potentiation and depression of synaptic excitation between hippocampal CA3-CA1 cell pairs in vitro. Proc Natl Acad Sci U S A (1996) 1.20
Intraductal mono-octanoin for the direct dissolution of bile duct stones: experience in 343 patients. Gut (1986) 1.18
Plasma beta-endorphin, adrenocorticotropin hormone, and cortisol in autism. J Child Psychol Psychiatry (1997) 1.18
Presynaptic inhibition of excitatory synaptic transmission by muscarinic and metabotropic glutamate receptor activation in the hippocampus: are Ca2+ channels involved? Neuropharmacology (1995) 1.18
Screening scale predicts patients successfully receiving long-term implantable left ventricular assist devices. Circulation (1995) 1.16
Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients. Gastroenterology (1975) 1.16
Validity and sensitivity of an intravenous bile acid tolerance test in patients with liver disease. N Engl J Med (1975) 1.16
Pretreatment biliary lipid composition in white patients with radiolucent gallstones in the National Cooperative Gallstone Study. Gastroenterology (1982) 1.14
One-step quantitative extraction of medium-chain and long-chain fatty acids from aqueous samples. J Lipid Res (1969) 1.13
Metabolism of lethocholate in healthy man. I. Biotransformation and biliary excretion of intravenously administered lithocholate, lithocholylglycine, and their sulfates. Gastroenterology (1975) 1.12
Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-nor-ursodeoxycholate in rodents. Gastroenterology (1986) 1.12
Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides. Arthritis Rheum (1986) 1.10
Identification and characterization of genes required for hyphal morphogenesis in the filamentous fungus Aspergillus nidulans. Genetics (1999) 1.10
Increased reflux of bile into the stomach in gastric ulcer. Gut (1968) 1.10
Calcium-independent actions of alpha-latrotoxin on spontaneous and evoked synaptic transmission in the hippocampus. J Neurophysiol (1996) 1.10
Nocturnal gallbladder storage and emptying in gallstone patients and healthy subjects. Gastroenterology (1978) 1.09
Silencing the beeper. N Engl J Med (1980) 1.09
Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells. Am J Physiol (1998) 1.09
Chemistry and enterohepatic circulation of bile acids. Hepatology (1984) 1.09
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. I. Cholylglycine. J Clin Invest (1972) 1.09