Published in Ann N Y Acad Sci on April 21, 1995
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest (2003) 2.23
Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. Cell Metab (2008) 2.17
Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation. Int J Exp Pathol (2000) 1.86
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. J Exp Med (2002) 1.67
Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med (2001) 1.29
The mechanisms of coronary restenosis: insights from experimental models. Int J Exp Pathol (2000) 1.22
Association between bone mineral densities and serum lipid profiles of pre- and post-menopausal rural women in South Korea. Osteoporos Int (2005) 1.18
Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves. J Clin Invest (1997) 1.16
Lipid profile, obesity and bone mineral density: the Hertfordshire Cohort Study. QJM (2007) 1.06
Increased serum osteopontin is a risk factor for osteoporosis in menopausal women. Osteoporos Int (2010) 1.05
Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. Am J Pathol (2006) 1.03
Inhibition of matrix metalloproteinases improves left ventricular function in mice lacking osteopontin after myocardial infarction. Mol Cell Biochem (2008) 1.00
Integrin alphavbeta3 is expressed in selected microvessels after focal cerebral ischemia. Am J Pathol (1996) 0.98
Established and newly proposed mechanisms of chronic cyclosporine nephropathy. Korean J Intern Med (2009) 0.97
The role of ERK signaling in protein hydrogel remodeling by vascular smooth muscle cells. Biomaterials (2007) 0.93
Clinical and echocardiographic correlates of plasma osteopontin in the community: the Framingham Heart Study. Heart (2006) 0.87
Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis. BMC Genomics (2009) 0.84
Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2012) 0.83
Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4. Stem Cell Res Ther (2015) 0.81
Mechanisms of Healing in Coiled Intracranial Aneurysms: A Review of the Literature. AJNR Am J Neuroradiol (2014) 0.81
Association between the hypomethylation of osteopontin and integrin β3 promoters and vascular smooth muscle cell phenotype switching in great saphenous varicose veins. Int J Mol Sci (2014) 0.81
Clinical Application of Mesenchymal Stem Cells and Novel Supportive Therapies for Oral Bone Regeneration. Biomed Res Int (2015) 0.79
Osteopontin expression in reactive lesions of gingiva. J Appl Oral Sci (2015) 0.79
Osteopontin regulates anabolic effect in human menopausal osteoporosis with intermittent parathyroid hormone treatment. Osteoporos Int (2010) 0.78
Human osteopontin: Potential clinical applications in cancer (Review). Int J Mol Med (2017) 0.75
Inhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin Cleavage. PLoS One (2016) 0.75
Plasma Osteopontin Levels and Adverse Cardiovascular Outcomes in the PEACE Trial. PLoS One (2016) 0.75
Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases. J Immunol Res (2016) 0.75
The Effect of Osteopontin on Microglia. Biomed Res Int (2017) 0.75
Re-expression of pro-fibrotic, embryonic preserved mediators in irradiated arterial vessels of the head and neck region. Strahlenther Onkol (2017) 0.75
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation (1986) 19.82
Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol (2000) 14.59
Phosphate regulation of vascular smooth muscle cell calcification. Circ Res (2000) 5.18
Selection and characterization of bovine aortic endothelial cells. In Vitro (1978) 4.09
Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization. J Clin Invest (1988) 3.76
Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy. Am J Psychiatry (1994) 3.75
Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol (2001) 3.66
Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci U S A (1989) 3.37
Replication of smooth muscle cells in vascular disease. Circ Res (1986) 2.98
Cell proliferation in human coronary arteries. Proc Natl Acad Sci U S A (1990) 2.90
Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse. Arterioscler Thromb Vasc Biol (2000) 2.77
Production of transforming growth factor beta 1 during repair of arterial injury. J Clin Invest (1991) 2.70
Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation (1999) 2.68
Inhibition of endothelial regeneration by type-beta transforming growth factor from platelets. Science (1986) 2.67
Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest (1992) 2.62
Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest (1993) 2.60
Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest (1991) 2.58
Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci U S A (2009) 2.51
NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. J Cell Biol (1998) 2.49
Endothelial regeneration. III. Time course of intimal changes after small defined injury to rat aortic endothelium. Lab Invest (1981) 2.46
Expression of the sis gene by endothelial cells in culture and in vivo. Proc Natl Acad Sci U S A (1984) 2.41
Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study. J Thromb Haemost (2007) 2.40
Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall. Circ Res (1991) 2.39
Population-based study of tamoxifen therapy and subsequent ovarian, endometrial, and breast cancers. J Natl Cancer Inst (1995) 2.36
Developmentally regulated production of platelet-derived growth factor-like molecules. Nature (1984) 2.30
Significance of quiescent smooth muscle migration in the injured rat carotid artery. Circ Res (1985) 2.28
PDGF ligand and receptor gene expression during repair of arterial injury. J Cell Biol (1990) 2.26
The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest (1995) 2.23
Skeletal myoblast transplantation for repair of myocardial necrosis. J Clin Invest (1996) 2.20
Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood (1997) 2.15
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem (2001) 2.12
Lipopolysaccharide-mediated bovine endothelial cell injury in vitro. Lab Invest (1983) 2.08
Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J Clin Invest (1995) 2.02
Cell replication in the aortic endothelium: a new method for study of the problem. Lab Invest (1973) 1.99
Cervical cancer screening among Cambodian-American women. Cancer Epidemiol Biomarkers Prev (1999) 1.95
Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD. J Clin Invest (1996) 1.94
An endothelial cell-derived growth factor. J Cell Biol (1980) 1.93
Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells. Proc Natl Acad Sci U S A (1988) 1.92
Congenital malformations in newborns of women with established and gestational diabetes in Washington State, 1984-91. Paediatr Perinat Epidemiol (1996) 1.91
Human papillomavirus 16 and 18 L1 serology compared across anogenital cancer sites. Cancer Res (2001) 1.89
Renal injury from angiotensin II-mediated hypertension. Hypertension (1992) 1.88
Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo. Am J Pathol (1998) 1.83
Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study. Obstet Gynecol (2000) 1.82
Human embryonic stem cell-derived cardiomyocytes engraft but do not alter cardiac remodeling after chronic infarction in rats. J Mol Cell Cardiol (2010) 1.75
Endothelial regeneration. V. Inhibition of endothelial regrowth in arteries of rat and rabbit. Lab Invest (1983) 1.75
Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol (1994) 1.74
Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res (1994) 1.73
Cofactors with human papillomavirus in a population-based study of vulvar cancer. J Natl Cancer Inst (1997) 1.72
Human papillomavirus infection and survival in oral squamous cell cancer: a population-based study. Otolaryngol Head Neck Surg (2001) 1.71
Electromechanical coupling between skeletal and cardiac muscle. Implications for infarct repair. J Cell Biol (2000) 1.66
Angiogenesis in human coronary atherosclerotic plaques. Am J Pathol (1994) 1.65
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect Immun (1999) 1.65
Alpha-v beta-3 integrin expression in normal and atherosclerotic artery. Circ Res (1995) 1.64
Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasia. Circ Res (1982) 1.64
Risk of stroke in young women and two prothrombotic mutations: factor V Leiden and prothrombin gene variant (G20210A) Stroke (1998) 1.63
Endothelial regneration. I. Quantitative analysis of initial stages of endothelial regeneration in rat aortic intima. Lab Invest (1978) 1.63
Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction. Am J Pathol (2001) 1.61
Critical aortic stenosis in the neonate. A comparison of balloon valvuloplasty and transventricular dilation. J Thorac Cardiovasc Surg (1995) 1.61
Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis. Kidney Int (1999) 1.60
Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells. Nat Med (2000) 1.60
The aortic intima. II. Repair of the aortic lining after mechanical denudation. Am J Pathol (1975) 1.59
Rat carotid neointimal smooth muscle cells reexpress a developmentally regulated mRNA phenotype during repair of arterial injury. Circ Res (1992) 1.59
Micro magnetic resonance angiography of the finger in systemic sclerosis. Rheumatology (Oxford) (2008) 1.58
Endothelial regeneration. II. Restitution of endothelial continuity. Lab Invest (1979) 1.58
Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J Urol (1999) 1.58
Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin. Circ Res (2001) 1.56
Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction? Cancer Epidemiol Biomarkers Prev (1999) 1.55
The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. Genes Dev (1996) 1.54
OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40. J Immunol (1998) 1.54
Smooth muscle cell hypertrophy versus hyperplasia in hypertension. Proc Natl Acad Sci U S A (1981) 1.51
Endothelial injury and regeneration. IV. Endotoxin: a nondenuding injury to aortic endothelium. Lab Invest (1983) 1.50
Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy. Circ Res (1993) 1.49
Tamoxifen therapy for breast cancer and endometrial cancer risk. J Natl Cancer Inst (1999) 1.47
Breast cancer incidence in Asian migrants to the United States and their descendants. Epidemiology (1995) 1.45
MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A (1997) 1.44
High efficiency myogenic conversion of human fibroblasts by adenoviral vector-mediated MyoD gene transfer. An alternative strategy for ex vivo gene therapy of primary myopathies. J Clin Invest (1998) 1.43
Colorectal cancer incidence in Asian migrants to the United States and their descendants. Cancer Causes Control (2000) 1.42
A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood (1997) 1.42
Proliferation and the monoclonal origins of atherosclerotic lesions. Annu Rev Med (1998) 1.42
The role of membrane-membrane interactions in the regulation of endothelial cell growth. J Cell Biol (1985) 1.41
Left ventricular morphology influences mortality after the Norwood operation. Heart (2009) 1.40
Activated neutrophils disrupt endothelial monolayer integrity by an oxygen radical-independent mechanism. Lab Invest (1985) 1.40
Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype. J Biol Chem (2001) 1.39
Evaluation of a fiberoptic blood gas monitor in neonates with congenital heart disease. Respir Care (2000) 1.39
Screening and treatment of distress. J Consult Clin Psychol (2001) 1.38
Severe left ventricular hypertrophy in pediatric dialysis: prevalence and predictors. Pediatr Nephrol (2000) 1.38
Vascular wall growth control: the role of the endothelium. Arteriosclerosis (1981) 1.35
Del1 induces integrin signaling and angiogenesis by ligation of alphaVbeta3. J Biol Chem (1999) 1.34
Neutrophil-endothelial cell interactions on endothelial monolayers grown on micropore filters. J Clin Invest (1981) 1.34
Liver cancer in Asian migrants to the United States and their descendants. Cancer Causes Control (1996) 1.34
Childhood brain tumor occurrence in relation to residential power line configurations, electric heating sources, and electric appliance use. Am J Epidemiol (1996) 1.33
Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activation. J Biol Chem (1999) 1.32
Clustering of replicating cells in aortic endothelium. Proc Natl Acad Sci U S A (1976) 1.31
Salt-sensitive hypertension develops after short-term exposure to Angiotensin II. Hypertension (1999) 1.29
Validation of a cognitive test for delirium in medical ICU patients. Psychosomatics (1996) 1.29
Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med (2001) 1.29
Characterization of cloned aortic smooth muscle cells from young rats. Am J Pathol (1994) 1.29