Published in Int J Exp Pathol on April 01, 1995
Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr (2006) 2.83
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J (2005) 2.34
Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr (2007) 1.76
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
The fetal origins of memory: the role of dietary choline in optimal brain development. J Pediatr (2006) 1.19
The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest (1955) 31.08
Serum glutamic pyruvic transaminase in cardiac with hepatic disease. Proc Soc Exp Biol Med (1956) 5.91
Signaling through phosphatidylcholine breakdown. J Biol Chem (1990) 5.36
Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger. Proc Natl Acad Sci U S A (1986) 2.54
In vivo studies on pathways for the biosynthesis of lecithin in the rat. J Lipid Res (1966) 1.64
Boehringer Mannheim Award lecture. Phosphatidylcholine metabolism: masochistic enzymology, metabolic regulation, and lipoprotein assembly. Biochem Cell Biol (1990) 1.32
Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets. Carcinogenesis (1983) 1.22
The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens. Carcinogenesis (1984) 1.08
Choline-deficiency fatty liver: impaired release of hepatic triglycerides. J Lipid Res (1968) 1.08
Effects of choline deficiency on rat hepatocytes. Fed Proc (1971) 1.03
Choline phospholipids: signal transduction and carcinogenesis. FASEB J (1993) 0.98
Studies on ethionine. VI. Sex-dependent behavior of methionine and ethionine in rats. J Biol Chem (1963) 0.97
Sex difference in ethionine inhibition of hepatic protein synthesis. J Biol Chem (1958) 0.93
Hepatocarcinogenic and promoting action of a choline-devoid diet in the rat. Cancer Res (1985) 0.92
Phospholipase C-mediated hydrolysis of phosphatidylcholine is a target of transforming growth factor beta 1 inhibitory signals. Mol Cell Biol (1992) 0.88
Sex differences in the metabolism of phosphatidyl cholines in rat liver. Biochim Biophys Acta (1967) 0.87
Choline enhances acetylaminofluorene promotion of liver carcinogenesis in female but not in male rats. Carcinogenesis (1992) 0.86
Regulation of protein turnover versus growth state: ascites hepatoma as a model for studies both in the animal and in vitro. Arch Biochem Biophys (1987) 0.83
Phosphatidylcholine peroxidation and liver cancer in mice fed a choline-deficient diet with ethionine. Free Radic Biol Med (1993) 0.82
Resistance of female Fischer-344 rats to the hepatonecrogenic and hepatocarcinogenic actions of a choline-devoid diet. Carcinogenesis (1991) 0.80
Differential effects of choline administration on liver microsomes of female and male rats. Exp Mol Pathol (1978) 0.80
Mechanisms of the enhanced liver carcinogenesis by choline in female rats: delay in liver growth after partial hepatectomy and stimulation of 2-AAF mitoinhibition. Carcinogenesis (1992) 0.80
Ethynylestradiol protection against methyl insufficiency in castrated male Wistar/Furth rats fed a methionine-choline-deficient diet. Carcinogenesis (1993) 0.79
Studies on ethionine. V. Sex difference in incorporation in vivo of ethionine into rat proteins. J Biol Chem (1961) 0.78
Effect of choline administration on the toxicity of N-nitrosodimethylamine in female rats. Toxicol Appl Pharmacol (1977) 0.78
Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast. N Engl J Med (1981) 7.53
Radiotherapy after breast-preserving surgery in women with localized cancer of the breast. N Engl J Med (1993) 3.54
Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am J Pathol (1998) 2.62
Local recurrences and distant metastases after conservative breast cancer treatments: partly independent events. J Natl Cancer Inst (1995) 2.52
Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomised trials on 1,973 patients. Eur J Cancer (1995) 2.30
Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more. J Natl Cancer Inst (1990) 2.25
Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells. Gastroenterology (1997) 2.16
Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes. Biochem J (1982) 2.11
Does postoperative radiation therapy represent a contraindication to expander-implant based immediate breast reconstruction? An update 2012-2014. Eur Rev Med Pharmacol Sci (2015) 2.09
Squamous cell carcinoma of the penis. J Am Acad Dermatol (1996) 2.06
Comparison of Halsted mastectomy with quadrantectomy, axillary dissection, and radiotherapy in early breast cancer: long-term results. Eur J Cancer Clin Oncol (1986) 2.05
Public health. The cholera crisis in Africa. Science (2009) 2.02
Production of antiendomysial antibodies after in-vitro gliadin challenge of small intestine biopsy samples from patients with coeliac disease. Lancet (1996) 1.94
Which kinds of lymph node metastases can FDG PET detect? A clinical study in melanoma. J Nucl Med (2000) 1.93
Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J Neurosci (2001) 1.86
Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types. J Biol Chem (1998) 1.83
Altered maturation of peripheral blood dendritic cells in patients with breast cancer. Br J Cancer (2003) 1.65
Central small size breast cancer: how to overcome the problem of nipple and areola involvement. Eur J Cancer (1993) 1.61
HNE interacts directly with JNK isoforms in human hepatic stellate cells. J Clin Invest (1998) 1.59
Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions. Biochem J (1985) 1.58
Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochem Biophys Res Commun (1993) 1.51
Risk of internal mammary lymph node metastases and its relevance on prognosis of breast cancer patients. Ann Surg (1983) 1.50
Distribution of axillary node metastases by level of invasion. An analysis of 539 cases. Cancer (1987) 1.48
Right ventricular myocardial function in ARF patients. PEEP as a challenge for the right heart. Intensive Care Med (1996) 1.44
Diminished response to cytotoxic therapy in G-6-PD deficiency. Lancet (1980) 1.39
On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis. Free Radic Biol Med (1996) 1.38
Hip fractures in Italy: 2000-2005 extension study. Osteoporos Int (2009) 1.36
Electron spin resonance studies on normal human uterus and cervix and on benign and malignant uterine tumors. Cancer Res (1981) 1.36
Exploring users' experiences of accessing out-of-hours primary medical care services. Qual Saf Health Care (2007) 1.33
Effect of CCl-4 in vitro and in vivo on lipid peroxidation of rat liver homogenates and subcellular fractions. Enzymologia (1965) 1.33
Mortality reduction in cardiac anesthesia and intensive care: results of the first International Consensus Conference. Acta Anaesthesiol Scand (2011) 1.31
Neural correlates of cognitive control of reaching movements in the dorsal premotor cortex of rhesus monkeys. J Neurophysiol (2011) 1.29
Liver regeneration in response to partial hepatectomy in rats treated with retrorsine: a kinetic study. J Hepatol (1999) 1.28
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Prognosis of breast cancer patients after mastectomy and dissection of internal mammary nodes. Ann Surg (1985) 1.27
Hepatic cholesterol in lead nitrate induced liver hyperplasia. Chem Biol Interact (1984) 1.26
4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications. Antioxid Redox Signal (1999) 1.24
The role of lipid peroxidation in liver damage. Chem Phys Lipids (1988) 1.24
Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis. Hepatology (1992) 1.23
Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2. Cell Death Differ (2008) 1.22
Cholesterol content in tumor tissues is inversely associated with high-density lipoprotein cholesterol in serum in patients with gastrointestinal cancer. Cancer (1994) 1.20
Assessing the professional performance of UK doctors: an evaluation of the utility of the General Medical Council patient and colleague questionnaires. Qual Saf Health Care (2008) 1.20
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
Specific helium-neon laser sensitivity of the purified cytochrome c oxidase. Int J Radiat Biol (2000) 1.18
Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine. Am J Pathol (2001) 1.17
Conservative treatment of breast cancer. A trial in progress at the Cancer Institute of Milan. Cancer (1977) 1.16
Capturing users' experience of UK out-of-hours primary medical care: piloting and psychometric properties of the Out-of-hours Patient Questionnaire. Qual Saf Health Care (2007) 1.14
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
A novel frameshift mutation of the mtDNA COIII gene leads to impaired assembly of cytochrome c oxidase in a patient affected by Leigh-like syndrome. Hum Mol Genet (2000) 1.13
Assessment of hospitalised cancer patients' needs by the Needs Evaluation Questionnaire. Ann Oncol (2000) 1.13
Association between [18F]fluorodeoxyglucose uptake and postoperative histopathology, hormone receptor status, thymidine labelling index and p53 in primary breast cancer: a preliminary observation. Eur J Nucl Med (1998) 1.11
Quantitative and qualitative cosmetic evaluation after conservative treatment for breast cancer. Eur J Cancer (1991) 1.11
Mortality reduction in cardiac anesthesia and intensive care: results of the first International Consensus Conference. HSR Proc Intensive Care Cardiovasc Anesth (2011) 1.11
A growth-constrained environment drives tumor progression invivo. Proc Natl Acad Sci U S A (2001) 1.11
Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. Lab Invest (1985) 1.09
Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study. Int J Obes (Lond) (2010) 1.09
Choline-deficiency fatty liver: impaired release of hepatic triglycerides. J Lipid Res (1968) 1.08
Distribution, density, and Lyme disease spirochete infection in Ixodes dammini (Acari: Ixodidae) on white-tailed deer in Maryland. J Med Entomol (1992) 1.07
Conservation surgery after primary chemotherapy in large carcinomas of the breast. Ann Surg (1995) 1.07
Expression of protein tyrosine phosphatase alpha (RPTPalpha) in human breast cancer correlates with low tumor grade, and inhibits tumor cell growth in vitro and in vivo. Oncogene (2000) 1.07
Sexual practices and attitudes of street youth in Belo Horizonte, Brazil. Street Youth Study Group. Soc Sci Med (1993) 1.07
The effect of rifampicin on mitochondrial RNA polymerase from rat liver. FEBS Lett (1970) 1.06
Cholesterol metabolism during the growth of a rat ascites hepatoma (Yoshida AH-130). Br J Cancer (1992) 1.06
Observation of a charged charmoniumlike structure in e+ e- → π+ π- J/ψ at sqrt[s] = 4.26 GeV. Phys Rev Lett (2013) 1.05
Possible role of aldehydic lipid peroxidation products as chemoattractants. Int J Tissue React (1987) 1.05
Growth kinetics and structure of fibrin gels. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 1.05
Gluten-sensitive disease with mild enteropathy. Gastroenterology (1996) 1.03
Chemotactic activity of the lipid peroxidation product 4-hydroxynonenal and homologous hydroxyalkenals. Biol Chem Hoppe Seyler (1986) 1.03
Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E. J Investig Med (1999) 1.02
Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells. J Biol Chem (2000) 1.01
Studies on fatty liver with isolated hepatocytes. II. The action of carbon tetrachloride on lipid peroxidation, protein, and triglyceride synthesis and secretion. Exp Mol Pathol (1979) 1.01
Increased risk of acute myeloid leukaemia due to polymorphisms in detoxification and DNA repair enzymes. Ann Oncol (2007) 1.00
Social networks and daily activities of street youth in Belo Horizonte, Brazil. Street Youth Study Group. Child Dev (1994) 0.99
Cell deletion by apoptosis during regression of renal hyperplasia. Am J Pathol (1989) 0.98
The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial. Osteoarthritis Cartilage (2013) 0.98
Transplantation of normal hepatocytes modulates the development of chronic liver lesions induced by a pyrrolizidine alkaloid, lasiocarpine. Carcinogenesis (1995) 0.97
Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique. Chem Biol Interact (1985) 0.97
The influence of radiotherapy on cosmetic outcome after breast conservative surgery. Int J Radiat Oncol Biol Phys (1995) 0.97
Single dilator vs. guide wire dilating forceps tracheostomy: a meta-analysis of randomised trials. Acta Anaesthesiol Scand (2013) 0.97
Hepatic glucose-6-phosphate dehydrogenase, cholesterogenesis, and serum lipoproteins in liver regeneration after partial hepatectomy. Exp Mol Pathol (1986) 0.97
Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-azacytidine. Leukemia (2011) 0.97
Spin trapping of free radical species produced during the microsomal metabolism of ethanol. Chem Biol Interact (1988) 0.96
Cell proliferation and promotion of rat liver carcinogenesis: different effect of hepatic regeneration and mitogen induced hyperplasia on the development of enzyme-altered foci. Carcinogenesis (1990) 0.96
Radioimmunoassay to detect antitransglutaminase autoantibodies is the most sensitive and specific screening method for celiac disease. Am J Gastroenterol (2001) 0.96
Alteration of Na+ homeostasis as a critical step in the development of irreversible hepatocyte injury after adenosine triphosphate depletion. Hepatology (1995) 0.96
Prognosis of breast cancer with axillary node metastases after surgical treatment only. Eur J Cancer Clin Oncol (1987) 0.95
The performance of poly-epsilon-caprolactone scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4. Biomaterials (2007) 0.95
Effects of carbon tetrachloride on isolated rat liver cells: stimulation of lipid peroxidation and inhibitory action of free-radical scavengers [proceedings]. Biochem Soc Trans (1978) 0.94
Novel heteroplasmic mtDNA mutation in a family with heterogeneous clinical presentations. Ann Neurol (2002) 0.94
An in-school CD-ROM asthma education program. J Sch Health (2000) 0.94
Prospective evaluation of fluorine-18-FDG PET in presurgical staging of the axilla in breast cancer. J Nucl Med (1998) 0.93
Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma. Ann Oncol (2007) 0.93
Paracetamol-stimulated lipid peroxidation in isolated rat and mouse hepatocytes. Chem Biol Interact (1983) 0.93
Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells. Cancer Res (1986) 0.93
Isolated cavernous sinus extramedullary relapse of chronic myelogenous leukemia following allogeneic stem cell transplant. Ann Hematol (2002) 0.93
Systemic cross-linked N-terminal telopeptide and procollagen I C-terminal extension peptide as markers of bone turnover after total hip arthroplasty. J Bone Joint Surg Br (2005) 0.93
The role of lipid peroxidation in CCl4-induced damage to liver microsomal enzymes: comparative studies in vitro using microsomes and isolated liver cells. Chem Biol Interact (1981) 0.93
Chemotactic activity of hydroxyalkenals on rat neutrophils. Int J Tissue React (1985) 0.92
Norfloxacin prophylaxis for neutropenic patients undergoing bone marrow transplantation. Bone Marrow Transplant (1989) 0.92
Efficacy, toxicity, and applicability of high-dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: five-year results. J Clin Oncol (1997) 0.91