Published in Hepatology on January 01, 1995
Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction. Eur J Clin Pharmacol (2008) 2.36
Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease. Drug Metab Dispos (2009) 1.67
Comparative Clinical Pharmacokinetics and Pharmacodynamics of HIV-1 Integrase Strand Transfer Inhibitors. Clin Pharmacokinet (2016) 0.85
Expression of P450 and nuclear receptors in normal and end-stage Chinese livers. World J Gastroenterol (2014) 0.85
Development of a Physiologically-Based Pharmacokinetic Model for Sirolimus: Predicting Bioavailability Based on Intestinal CYP3A Content. CPT Pharmacometrics Syst Pharmacol (2013) 0.83
Buprenorphine maintenance and mu-opioid receptor availability in the treatment of opioid use disorder: implications for clinical use and policy. Drug Alcohol Depend (2014) 0.82
Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis. Eur J Clin Pharmacol (2011) 0.81
The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity. Int J Mol Sci (2016) 0.79
A study of the relationship between serum bile acids and propranolol pharmacokinetics and pharmacodynamics in patients with liver cirrhosis and in healthy controls. PLoS One (2014) 0.78
Impaired irinotecan biotransformation in hepatic microsomal fractions from patients with chronic liver disease. Br J Clin Pharmacol (2010) 0.78
Clinical pharmacokinetics and pharmacodynamics of the endothelin receptor antagonist macitentan. Clin Pharmacokinet (2015) 0.78
Study of the Urinary Ratio of 6 beta-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases. Biomark Insights (2007) 0.77
Can paracetamol (acetaminophen) be administered to patients with liver impairment? Br J Clin Pharmacol (2015) 0.77
Effect of biliary obstruction and internal biliary drainage on hepatic cytochrome P450 isozymes in rats. World J Gastroenterol (2008) 0.77
Drug interactions: a primer for the gastroenterologist. Gastroenterol Hepatol (N Y) (2012) 0.77
Severe liver cirrhosis markedly reduces AhR-mediated induction of cytochrome P450 in rats by decreasing the transcription of target genes. PLoS One (2013) 0.77
Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma. Oncotarget (2016) 0.76
Gut-liver axis improves with meloxicam treatment after cirrhotic liver resection. World J Gastroenterol (2014) 0.76
Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach. Oncotarget (2016) 0.76
Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importance. World J Gastroenterol (2016) 0.75
Significance of the (13)C-caffeine breath test for patients with cirrhosis. Ann Gastroenterol (2014) 0.75
Serum alanine transaminase total bilirubin concentrations predict CYP3A activity as measured by midazolam and 1'-hydroxylation. Med Sci Monit (2015) 0.75
Pharmacokinetics of the New Hepatitis C Virus NS3 Protease Inhibitor Narlaprevir following Single-Dose Use with or without Ritonavir in Patients with Liver Cirrhosis. Antimicrob Agents Chemother (2016) 0.75
Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage Adjustments. Ther Adv Infect Dis (2014) 0.75
Experimental protoporphyria: effect of bile acids on liver damage induced by griseofulvin. Biomed Res Int (2015) 0.75
Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics. Drug Metab Dispos (2016) 0.75
The effect of mild and moderate hepatic impairment on the pharmacokinetics of valdecoxib, a selective COX-2 inhibitor. Eur J Clin Pharmacol (2005) 0.75
150 Patients with cardiac infarction treated in a coronary unit. Lancet (1967) 5.29
Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature (1981) 4.72
Epidemiology and host- and variety-dependent characteristics of infection due to Cryptococcus neoformans in Australia and New Zealand. Australasian Cryptococcal Study Group. Clin Infect Dis (2000) 3.71
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest (2000) 3.17
Etiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis (2001) 2.63
The development of smoking during adolescence--the MRC/Derbyshire Smoking Study. Int J Epidemiol (1983) 2.61
Hepatitis C virus in intravenous drug users. Med J Aust (1990) 2.33
Cost-effectiveness of cimetidine maintenance therapy in chronic gastric and duodenal ulcer. Gastroenterology (1990) 2.32
An improved parasitological technique for the diagnosis of African trypanosomiasis. Trans R Soc Trop Med Hyg (1977) 2.27
The nature of immunosuppression in Trypanosoma brucei infections in mice. II. The role of the T and B lymphocytes. Immunology (1974) 2.23
Androgen-induced hepatoma. Lancet (1975) 2.21
Results of the Scoliosis Research Society instrument for evaluation of surgical outcome in adolescent idiopathic scoliosis. A multicenter study of 244 patients. Spine (Phila Pa 1976) (1999) 2.21
Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology (1998) 2.19
The cost effectiveness of alpha interferon in the treatment of chronic active hepatitis C. Med J Aust (1994) 2.15
Barriers to successful tuberculosis treatment in Tomsk, Russian Federation: non-adherence, default and the acquisition of multidrug resistance. Bull World Health Organ (2007) 2.09
Michael Murray, ND a natural approach to health. Interview by Bonnie Horrigan. Altern Ther Health Med (1999) 2.03
Nutrition support in clinical practice: review of published data and recommendations for future research directions. National Institutes of Health, American Society for Parenteral and Enteral Nutrition, and American Society for Clinical Nutrition. JPEN J Parenter Enteral Nutr (1997) 1.94
Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization. J Virol (1992) 1.94
Susceptibility of inbred strains of mice to Trypanosoma congolense: correlation with changes in spleen lymphocyte populations. Clin Exp Immunol (1978) 1.90
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology (1996) 1.83
Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. J Neurosci (1999) 1.82
The nature of immunosuppression in Trypanosoma brucei infections in mice. I. The role of the macrophage. Immunology (1974) 1.81
Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress. Am J Physiol Gastrointest Liver Physiol (2001) 1.79
Host susceptibility to African trypanosomiasis: trypanotolerance. Adv Parasitol (1982) 1.75
Which patients with hepatitis C develop liver complications? Hepatology (2000) 1.73
Respiratory status and allergy nine to 10 years after acute bronchiolitis. Arch Dis Child (1997) 1.72
Neuropsychological dysfunction following repeat concussions in jockeys. J Neurol Neurosurg Psychiatry (2006) 1.71
Consultation in family practice obstetrics. Can Fam Physician (1995) 1.68
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
When and why children first start to smoke. Int J Epidemiol (1990) 1.61
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Triazolam and disinhibition. Lancet (1993) 1.54
Immunosuppression in Trypanosoma brucei infections in rats and mice. Trans R Soc Trop Med Hyg (1973) 1.53
Huntington's disease: clinical correlates of disability and progression. Neurology (2003) 1.52
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis. Lancet (1992) 1.51
Multicenter clinical trial of recombinant human insulin-like growth factor I in patients with acute renal failure. Kidney Int (1999) 1.51
What is the best predictor of spontaneous ventricular tachycardia and sudden death after myocardial infarction? Circulation (1991) 1.49
Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms. Gut (1985) 1.47
Mast cells and macromolecular leak in intestinal immunological reactions. The influence of sex of rats infected with Nippostrongylus brasiliensis. Immunology (1971) 1.46
Immune response of elderly individuals to a live attenuated varicella vaccine. J Infect Dis (1992) 1.45
Scintiphotographic evaluation of patients with suspected left ventricular aneurysm. Circulation (1974) 1.45
Some factors associated with mortality in perforated peptic ulcer: a case-control study. J Gastroenterol Hepatol (1996) 1.42
Renal graft thrombosis. A survey of 134 consecutive cases. Transplantation (1994) 1.42
Reproduction in a patient with trisomy 8 mosaicism: case report and literature review. Am J Med Genet (1998) 1.41
Antipyrine clearance and response to interferon treatment in patients with chronic active hepatitis C. Hepatology (1995) 1.41
A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA) Ann Intern Med (1991) 1.40
Dimensions of the human posterior septal space and coronary sinus. Am J Cardiol (1991) 1.40
Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta. Parasite Immunol (1995) 1.39
Maintaining effective pressure ulcer prevention programs. Medsurg Nurs (1994) 1.39
Confusion, cortical blindness and fever. Med J Aust (1995) 1.38
Comparison of sotalol with amiodarone for long-term treatment of spontaneous sustained ventricular tachyarrhythmia based on coronary artery disease. Eur Heart J (1999) 1.38
Diagnosing fever by touch: observational study. BMJ (1998) 1.38
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). Biochemistry (1997) 1.35
Spread of an emerging Mycobacterium tuberculosis drug-resistant strain in the western Cape of South Africa. Int J Tuberc Lung Dis (2007) 1.33
Enhanced drug metabolism in cigarette smokers. Br Med J (1976) 1.31
Factors that predict bleeding following endoscopic mucosal resection of large colonic lesions. Endoscopy (2011) 1.27
Rifampin chemoprophylaxis for household contacts of patients with invasive infections due to Haemophilus influenzae type b. J Pediatr (1981) 1.26
The biological suppression of malaria: an ecological and nutritional interrelationship of a host and two parasites. Am J Clin Nutr (1978) 1.25
Modification of vascular tone using iNOS under the control of a radiation-inducible promoter. Gene Ther (2000) 1.24
Experimental vaccinia infection of cattle: a comparison with other virus infections of cows' teats. Vet Rec (1971) 1.24
Respiratory syncytial virus matrix protein associates with nucleocapsids in infected cells. J Gen Virol (2002) 1.24
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
The relationship between bacterial cultures of the vaginal introitus and urinary infection. Br J Urol (1972) 1.23
Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat. Neurorehabil Neural Repair (2007) 1.23
Relative expression of progesterone receptors A and B in endometrioid cancers of the endometrium. Cancer Res (2001) 1.22
Transport of protein in goldfish optic nerve during regeneration. Exp Neurol (1969) 1.21
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Herbal hepatotoxicity: an expanding but poorly defined problem. J Gastroenterol Hepatol (2000) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF. Growth Factors (1990) 1.19
Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. Exp Neurol (2003) 1.19
Some factors associated with increased risk of smoking by children. J Child Psychol Psychiatry (1983) 1.18
Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin. Proc Natl Acad Sci U S A (1987) 1.17
Building and growing a hospital intranet: a case study. J Med Internet Res (2001) 1.17
The response of mice infected with T. brucei to the administration of sheep erythrocytes. Trans R Soc Trop Med Hyg (1973) 1.16
Changes in the morphology and amino acid incorporation of regenerating goldfish optic neurons. Exp Neurol (1969) 1.15
Restitution of function and collateral sprouting in the cat spinal cord: the partially hemisected animal. J Comp Neurol (1974) 1.15
NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry. J Biol Chem (2000) 1.15
Changes in criminal activity after entering methadone maintenance. Br J Addict (1992) 1.15
Anatomic VisualizeR: realizing the vision of a VR-based learning environment. Stud Health Technol Inform (1999) 1.15
An outbreak of drug-resistant tuberculosis caused by a Beijing strain in the western Cape, South Africa. Int J Tuberc Lung Dis (2006) 1.14
How hosts control worms. Nature (1997) 1.13
Drug metabolism in liver disease: activity of hepatic microsomal metabolizing enzymes. Clin Pharmacol Ther (1979) 1.13
Drug-induced cholestasis. Semin Gastrointest Dis (2001) 1.13
Effect of domperidone on the health-related quality of life of patients with symptoms of diabetic gastroparesis. Diabetes Care (1998) 1.12
Trypanosoma congolense: inheritance of susceptibility to infection in inbred strains of mice. Exp Parasitol (1979) 1.11
Left ventricular function in acute myocardial infarction evaluation by gated scintiphotography. Circulation (1974) 1.11
Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice. Lab Invest (1992) 1.11
PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice. Br J Cancer (2012) 1.10
A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proc Natl Acad Sci U S A (1997) 1.10
Comparison and validation of three measures of quality of life in patients with pulmonary hypertension. Intern Med J (2006) 1.10
Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2012) 1.10
Immune responses of elderly persons 4 years after receiving a live attenuated varicella vaccine. J Infect Dis (1994) 1.10
The pathology of Trypanosoma brucei infection in the rat. Res Vet Sci (1974) 1.10
Infective endocarditis: incidence and mortality in the North East Thames Region. Br Heart J (1988) 1.10