PubRank

P Strop

Author PubWeight™ 29.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sensitive, soluble chromogenic substrates for HIV-1 proteinase. J Biol Chem 1990 1.70
2 Synthetic peptides as substrates and inhibitors of human immune deficiency virus-1 protease. J Biol Chem 1988 1.35
3 Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites. Biochemistry 1992 1.33
4 Proteolytic processing of particle-associated retroviral polyproteins by homologous and heterologous viral proteinases. Eur J Biochem 1995 1.18
5 Structural and functional studies in vitro on the p6 protein from the HIV-1 gag open reading frame. Biochim Biophys Acta 1993 1.18
6 Assignment of the 1H nuclear magnetic resonance spectrum of the proteinase inhibitor IIA from bull seminal plasma by two-dimensional nuclear magnetic resonance at 500 MHz. J Mol Biol 1983 1.02
7 An engineered retroviral proteinase from myeloblastosis associated virus acquires pH dependence and substrate specificity of the HIV-1 proteinase. EMBO J 1992 0.98
8 Chromophoric and fluorophoric peptide substrates cleaved through the dipeptidyl carboxypeptidase activity of cathepsin B. Anal Biochem 1987 0.98
9 Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases. Biochem Biophys Res Commun 1990 0.95
10 Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor. Structure 1995 0.95
11 Cloning, bacterial expression, and characterization of the Mason-Pfizer monkey virus proteinase. J Biol Chem 1995 0.93
12 One-bead-one-structure combinatorial libraries. Biopolymers 1995 0.92
13 Crystal structures of dialkylglycine decarboxylase inhibitor complexes. J Mol Biol 1999 0.90
14 Sub-site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV-1. FEBS Lett 1990 0.89
15 Subsite specificity of the proteinase from myeloblastosis associated virus. FEBS Lett 1991 0.89
16 Processed enzymatically active protease (p15gag) of avian retrovirus obtained in an E. coli system expressing a recombinant precursor (Pr25lac-delta gag). FEBS Lett 1988 0.87
17 Reduced-bond tight-binding inhibitors of HIV-1 protease. Fine tuning of the enzyme subsite specificity. FEBS Lett 1992 0.86
18 Substrates and inhibitors of human T-cell leukemia virus type 1 (HTLV-1) proteinase. Leukemia 1997 0.85
19 Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. J Biol Chem 1999 0.85
20 Configurations of diastereomeric hydroxyethylene isosteres strongly affect biological activities of a series of specific inhibitors of human-immunodeficiency-virus proteinase. Eur J Biochem 1997 0.83
21 Specificity mapping of HIV-1 protease by reduced bond inhibitors. Arch Biochem Biophys 1993 0.83
22 Isolation, biochemical characterization and crystallization of the p15gag proteinase of myeloblastosis associated virus expressed in E. coli. Int J Biochem 1992 0.83
23 High-level expression of enzymatically active bovine leukemia virus proteinase in E. coli. FEBS Lett 1991 0.82
24 Enzyme-mediated spatial segregation on individual polymeric support beads: application to generation and screening of encoded combinatorial libraries. Proc Natl Acad Sci U S A 1996 0.81
25 Potency comparison of peptidomimetic inhibitors against HIV-1 and HIV-2 proteinases: design of equipotent lead compounds. Arch Biochem Biophys 1997 0.81
26 Peptide inhibitors of HIV-1 and HIV-2 proteases: a comparative study. Leukemia 1997 0.80
27 A globular protein with slower amide proton exchange from an alpha helix than from antiparallel beta sheets. Biochem Biophys Res Commun 1984 0.79
28 One bead-one compound combinatorial peptide library: different types of screening. Methods Enzymol 1996 0.79
29 Structural studies of the retroviral proteinase from avian myeloblastosis associated virus. Proteins 1992 0.79
30 Myeloblastosis associated virus (MAV) proteinase site-mutated to be HIV-like has a higher activity and allows production of infectious but morphologically altered virus. Virology 1993 0.77
31 Discovery of a novel, potent, and specific family of factor Xa inhibitors via combinatorial chemistry. Biochemistry 1998 0.77
32 Substrate cleavage by HIV-1 proteinase. Adv Exp Med Biol 1991 0.76
33 Isolation of human haemopexin by bioaffinity chromatography on haeme-sepharose. J Chromatogr 1981 0.75
34 Model study of hydrophobic interactions of alpha- and beta-trypsin and alpha-chymotrypsin. J Chromatogr 1983 0.75
35 Characterization of the proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance. Stability, amide proton exchange and mobility of aromatic residues. J Mol Biol 1983 0.75
36 Biological tolerance of copolymers of 2-hydroxyethyl methacrylate-vinylpyridine. Polim Med 1976 0.75
37 Ion-exchange derivatives of Spheron. V. Sulphate and sulpho derivatives. J Chromatogr 1984 0.75
38 Separation of alkyl derivatives of uracil by solvophobic adsorption chromatography on spheron. J Chromatogr 1977 0.75
39 Modifying the substrate specificity of chymosin. Biochem Soc Trans 1991 0.75
40 Separation of oligonucleotides on ion-exchange derivatives of Spheron. J Chromatogr 1979 0.75
41 Similarity of hydrophobic properties of alpha-fetoprotein and albumin. Oncodev Biol Med 1981 0.75
42 Preliminary structural comparison of the proteinase isoinhibitors IIA and IIB from bull seminal plasma based on individual assignments of the 1H nuclear magnetic resonance spectra by two-dimensional nuclear magnetic resonance at 500 MHz. J Mol Biol 1983 0.75
43 A spectroscopic study of the hemin-human-alpha-fetoprotein system. Ann N Y Acad Sci 1983 0.75
44 15gag proteinase of myeloblastosis-associated virus: specificity studies with substrate-based inhibitors. Arch Biochem Biophys 1992 0.75
45 Fluorescence spectroscopy, fluorescence polarization, and circular dichroism in studies on pH-dependent changes in the alpha-fetoprotein molecule. Ann N Y Acad Sci 1983 0.75
46 Mapping the active site of factor Xa by selective inhibitors: an NMR and MD study. Proteins 1998 0.75
47 Chromatography of biopolymers and their fragments on ion-exchange derivatives of the hydrophilic macroporous synthetic gel spheron. J Chromatogr 1976 0.75
48 Conformational transitions of human alpha-1 fetoprotein and serum albumin at acid and alkaline pH. Int J Biochem 1984 0.75
49 Development of a nonradioactive ribonuclease H assay. Anal Biochem 1996 0.75