Published in J Am Coll Cardiol on November 01, 1994
Safety and efficiency of emergency department assessment of chest discomfort. CMAJ (2004) 2.09
Use of emergency observation and assessment wards: a systematic literature review. Emerg Med J (2003) 1.94
Chest pain with nondiagnostic electrocardiogram in the emergency department: a randomized controlled trial of two cardiac marker regimens. CMAJ (2000) 1.49
Waste in the U.S. Health care system: a conceptual framework. Milbank Q (2008) 1.41
Managing demand for secondary care services: the changing context. BMJ (1998) 1.35
Is a chest pain observation unit likely to be cost saving in a British hospital? Emerg Med J (2001) 1.26
Direct hospital costs of chest pain patients attending the emergency department: a retrospective study. BMC Emerg Med (2006) 1.15
ROMEO: a rapid rule out strategy for low risk chest pain. Does it work in a UK emergency department? Emerg Med J (2002) 1.11
The limited incorporation of economic analyses in clinical practice guidelines. J Gen Intern Med (2002) 1.10
Program description: a hospitalist-run, medical short-stay unit in a teaching hospital. CMAJ (2000) 1.10
Role of the short stay observation ward in accident and emergency departments in the United Kingdom. J Accid Emerg Med (1998) 1.03
Predicting observation unit treatment failures in patients with skin and soft tissue infections. Int J Emerg Med (2008) 0.97
Structure, process and outcomes of chest pain units established in the ESCAPE trial. Emerg Med J (2007) 0.94
Chest pain evaluation units West J Med (2000) 0.82
The Short Stay Unit as a new option for hospitals: a review of the scientific literature. Med Sci Monit (2011) 0.77
Acute chest pain--identification of patients at low risk for coronary events. The impact of symptoms, medical history and risk factors. Wien Klin Wochenschr (2004) 0.77
Identification of patients with evolving coronary syndromes by using statistical models with data from the time of presentation. Heart (2005) 0.77
Identifying Patient Risk: The Basis for Rational Discharge Planning After Acute Myocardial Infarction. J Thromb Thrombolysis (1996) 0.76
Observation Units as Substitutes for Hospitalization or Home Discharge. Ann Emerg Med (2015) 0.75
The NVVC working group guidelines for the management of patients with non-ST-elevation acute coronary syndromes. Neth Heart J (2002) 0.75
Triple Rule Out versus CT Angiogram Plus Stress Test for Evaluation of Chest Pain in the Emergency Department. West J Emerg Med (2015) 0.75
The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. JAMA (1996) 17.62
Relationship between cancer patients' predictions of prognosis and their treatment preferences. JAMA (1998) 12.60
Does housestaff discontinuity of care increase the risk for preventable adverse events? Ann Intern Med (1994) 10.29
Chronic fatigue syndrome: a working case definition. Ann Intern Med (1988) 9.12
Performance of a five-item mental health screening test. Med Care (1991) 8.76
Foundations of cost-effectiveness analysis for health and medical practices. N Engl J Med (1977) 8.60
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III. Science (1985) 8.53
Recommendations for reporting cost-effectiveness analyses. Panel on Cost-Effectiveness in Health and Medicine. JAMA (1996) 8.52
Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med (1977) 8.24
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation (1999) 8.17
Survival after cardiopulmonary resuscitation in the hospital. N Engl J Med (1983) 8.07
Clinical prediction rules. Applications and methodological standards. N Engl J Med (1985) 7.72
Five-hundred life-saving interventions and their cost-effectiveness. Risk Anal (1995) 7.45
Adverse outcomes of underuse of beta-blockers in elderly survivors of acute myocardial infarction. JAMA (1997) 7.42
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell (1985) 7.29
The value of the autopsy in three medical eras. N Engl J Med (1983) 7.00
Cyclin activation of p34cdc2. Cell (1990) 6.87
The role of cost-effectiveness analysis in health and medicine. Panel on Cost-Effectiveness in Health and Medicine. JAMA (1996) 6.80
Contaminant blood cultures and resource utilization. The true consequences of false-positive results. JAMA (1991) 6.28
Guided medication dosing for inpatients with renal insufficiency. JAMA (2001) 6.25
Forecasting coronary heart disease incidence, mortality, and cost: the Coronary Heart Disease Policy Model. Am J Public Health (1987) 6.21
Quality of informed consent in cancer clinical trials: a cross-sectional survey. Lancet (2001) 6.07
A clinical prediction rule for delirium after elective noncardiac surgery. JAMA (1994) 5.92
The cost effectiveness of combination antiretroviral therapy for HIV disease. N Engl J Med (2001) 5.89
Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments) Am J Respir Crit Care Med (1996) 5.82
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell (1995) 5.73
The emerging role of "hospitalists" in the American health care system. N Engl J Med (1996) 5.40
The recent decline in mortality from coronary heart disease, 1980-1990. The effect of secular trends in risk factors and treatment. JAMA (1997) 5.36
The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions. J Virol (1992) 5.30
The impact of a regulation restricting medical house staff working hours on the quality of patient care. JAMA (1993) 5.11
Drug complications in outpatients. J Gen Intern Med (2000) 5.04
The cost of a successful delivery with in vitro fertilization. N Engl J Med (1994) 4.94
Inactivation of the sodium current in Myxicola giant axons. Evidence for coupling to the activation process. J Gen Physiol (1972) 4.92
Performance of screening and diagnostic tests. Application of receiver operating characteristic analysis. Arch Gen Psychiatry (1987) 4.62
Adult (not internal) medicine. Ann Intern Med (1997) 4.60
Physician reporting compared with medical-record review to identify adverse medical events. Ann Intern Med (1993) 4.60
Probabilistic sensitivity analysis using Monte Carlo simulation. A practical approach. Med Decis Making (1985) 4.47
Confounding: essence and detection. Am J Epidemiol (1981) 4.47
Gains in life expectancy from medical interventions--standardizing data on outcomes. N Engl J Med (1998) 4.47
Quantitative description of sodium and potassium currents and computed action potentials in Myxicola giant axons. J Gen Physiol (1973) 4.44
Current- and voltage-clamped studies on Myxicola giant axons. Effect of tetrodotoxin. J Gen Physiol (1969) 4.36
A randomized trial of a computer-based intervention to reduce utilization of redundant laboratory tests. Am J Med (1999) 4.24
Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as compared with dual-chamber pacing. Pacemaker Selection in the Elderly Investigators. N Engl J Med (1998) 4.22
Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intracellular transport of the Gag precursor. J Virol (1993) 4.20
Potential identifiability and preventability of adverse events using information systems. J Am Med Inform Assoc (1995) 4.14
Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function. N Engl J Med (1985) 4.00
Is the professional satisfaction of general internists associated with patient satisfaction? J Gen Intern Med (2000) 3.83
Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients. Science (1985) 3.81
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J (1988) 3.77
Expected gains in life expectancy from various coronary heart disease risk factor modifications. Circulation (1991) 3.75
Comparative reproducibility and validity of systems for assessing cardiovascular functional class: advantages of a new specific activity scale. Circulation (1981) 3.74
The decline in ischemic heart disease mortality rates. An analysis of the comparative effects of medical interventions and changes in lifestyle. Ann Intern Med (1984) 3.71
Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am J Med (1989) 3.65
Health values of hospitalized patients 80 years or older. HELP Investigators. Hospitalized Elderly Longitudinal Project. JAMA (1998) 3.47
Preoperative renal risk stratification. Circulation (1997) 3.47
Evaluation of the patient with acute chest pain. N Engl J Med (2000) 3.42
Assessment of operative risk in patients undergoing lung resection. Importance of predicted pulmonary function. Chest (1994) 3.31
Predicting bacteremia in hospitalized patients. A prospectively validated model. Ann Intern Med (1990) 3.31
Cost-effectiveness of interventions to prevent or treat coronary heart disease. Annu Rev Public Health (1985) 3.31
Clinical outcomes and costs of transcatheter as compared with surgical closure of patent ductus arteriosus. The Patient Ductus Arteriosus Closure Comparative Study Group. N Engl J Med (1993) 3.27
A new HTLV-III/LAV protein encoded by a gene found in cytopathic retroviruses. Science (1986) 3.20
Antigens encoded by the 3'-terminal region of human T-cell leukemia virus: evidence for a functional gene. Science (1984) 3.20
Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners. Proc Natl Acad Sci U S A (1987) 3.18
Resuscitation preferences among patients with severe congestive heart failure: results from the SUPPORT project. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. Circulation (1998) 3.11
ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J (2009) 3.08
The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. Ann Intern Med (1995) 3.08
Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J Biol Chem (1991) 3.06
Carbon-halogen bond cleavage. 3. Studies on bacterial halidohrolases. J Biol Chem (1968) 3.06
Development of the 'Activities of Daily Vision Scale'. A measure of visual functional status. Med Care (1992) 3.06
A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients. Science (1985) 3.05
Critical pathways as a strategy for improving care: problems and potential. Ann Intern Med (1995) 3.03
Rapid classification of positive blood cultures. Prospective validation of a multivariate algorithm. JAMA (1992) 3.02
Effect of race on the presentation and management of patients with acute chest pain. Ann Intern Med (1993) 3.00
Generation and characterization of monoclonal antibodies to the putative CD4-binding domain of human immunodeficiency virus type 1 gp120. J Virol (1989) 3.00
Heterogeneity of therapeutic responses in asthma. Br Med Bull (2000) 2.86
Quality of informed consent: a new measure of understanding among research subjects. J Natl Cancer Inst (2001) 2.85
Rectification in instantaneous potassium current-voltage relations in Myxicola giant axons. J Physiol (1971) 2.84
Use and misuse of the term "cost effective" in medicine. N Engl J Med (1986) 2.82
Mutations in the cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein impair the incorporation of Env proteins into mature virions. J Virol (1993) 2.80
HIV-1 Langerhans' cell tropism associated with heterosexual transmission of HIV. Science (1996) 2.79
Distribution studies of salicylazosulfapyridine and its metabolites. Gastroenterology (1973) 2.72