Published in Mol Microbiol on September 01, 1993
A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc Natl Acad Sci U S A (1998) 9.05
RTX proteins: a highly diverse family secreted by a common mechanism. FEMS Microbiol Rev (2010) 2.13
Acylation of Escherichia coli hemolysin: a unique protein lipidation mechanism underlying toxin function. Microbiol Mol Biol Rev (1998) 1.49
Protein secretion by hybrid bacterial ABC-transporters: specific functions of the membrane ATPase and the membrane fusion protein. EMBO J (1995) 1.19
Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin. Infect Immun (1999) 1.19
Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells. Infect Immun (1995) 1.17
Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites. Infect Immun (2000) 1.15
RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharides. Proc Natl Acad Sci U S A (2008) 1.10
Acyltransferases in bacteria. Microbiol Mol Biol Rev (2013) 0.96
Re-evaluation of a bacterial antifreeze protein as an adhesin with ice-binding activity. PLoS One (2012) 0.94
Random and directed mutagenesis to elucidate the functional importance of helix II and F-989 in the C-terminal secretion signal of Escherichia coli hemolysin. J Bacteriol (1996) 0.90
Ehrlichia chaffeensis tandem repeat proteins and Ank200 are type 1 secretion system substrates related to the repeats-in-toxin exoprotein family. Front Cell Infect Microbiol (2011) 0.89
The C-terminal domain is essential for protective activity of the Bordetella pertussis adenylate cyclase-hemolysin. Infect Immun (1995) 0.89
Modulation of the epithelial sodium channel (ENaC) by bacterial metalloproteases and protease inhibitors. PLoS One (2014) 0.85
Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens. PLoS One (2015) 0.82
Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme. Pathog Dis (2015) 0.82
Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3. Elife (2015) 0.80
Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro. Mol Microbiol (2016) 0.79
Directionality of substrate translocation of the hemolysin A Type I secretion system. Sci Rep (2015) 0.77
In vivo quantification of the secretion rates of the hemolysin A Type I secretion system. Sci Rep (2016) 0.75
A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc Natl Acad Sci U S A (1998) 9.05
The calmodulin-sensitive adenylate cyclase of Bordetella pertussis: cloning and expression in Escherichia coli. Mol Microbiol (1988) 4.15
The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18). J Exp Med (2001) 2.12
Bordetella pertussis adenylate cyclase. Purification, characterization, and radioimmunoassay. J Biol Chem (1986) 1.68
Protein-protein interaction between Bacillus stearothermophilus tyrosyl-tRNA synthetase subdomains revealed by a bacterial two-hybrid system. J Mol Microbiol Biotechnol (2001) 1.67
A bacterial two-hybrid system that exploits a cAMP signaling cascade in Escherichia coli. Methods Enzymol (2000) 1.63
Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli. J Biol Chem (1994) 1.41
Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase. Infect Immun (1990) 1.41
Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. Characterization of multiple calcium-binding sites and calcium-induced conformational changes. J Biol Chem (1995) 1.33
In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes. J Immunol (1996) 1.33
Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus. Proc Natl Acad Sci U S A (1997) 1.28
Identification of residues essential for catalysis and binding of calmodulin in Bordetella pertussis adenylate cyclase by site-directed mutagenesis. EMBO J (1989) 1.27
Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities. J Biol Chem (1992) 1.19
Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells. Proc Natl Acad Sci U S A (1998) 1.19
Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells. Infect Immun (1995) 1.17
High-level synthesis of active adenylate cyclase toxin of Bordetella pertussis in a reconstructed Escherichia coli system. Gene (1991) 1.16
Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope. J Immunol (1999) 1.13
Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway. J Immunol (1999) 1.11
Sensitive genetic screen for protease activity based on a cyclic AMP signaling cascade in Escherichia coli. J Bacteriol (2000) 1.07
Interaction of calmodulin with striatin, a WD-repeat protein present in neuronal dendritic spines. J Biol Chem (1998) 1.01
Characterization of ATP and calmodulin-binding properties of a truncated form of Bacillus anthracis adenylate cyclase. Biochemistry (1990) 0.98
Immunological relatedness between Bordetella pertussis and rat brain adenylyl cyclases. Biochemistry (1988) 0.97
Synthesis and secretion of Bordetella pertussis adenylate cyclase as a 200-kilodalton protein. Infect Immun (1990) 0.95
Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice. Mucosal Immunol (2011) 0.90
Expression and characterization of calcium-myristoyl switch proteins. Methods Enzymol (1995) 0.86
Bordetella pertussis adenylate cyclase: the gene and the protein. Tokai J Exp Clin Med (1988) 0.84
Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells. Methods Enzymol (2000) 0.83
Characterization of recombinant Bordetella pertussis adenylate cyclase toxins carrying passenger proteins. Res Microbiol (2001) 0.82
Characterization of mutant Bordetella pertussis adenylate cyclase toxins with reduced affinity for calmodulin. Implications for the mechanism of toxin entry into target cells. Eur J Biochem (1997) 0.81
Bordetella pertussis adenylate cyclase toxin as a tool to analyze molecular interactions in a bacterial two-hybrid system. Int J Med Microbiol (2000) 0.79
Bordetella pertussis adenylate cyclase toxin: a versatile screening tool. Toxicon (2002) 0.78
Ca2+-myristoyl switch and membrane binding of chemically acylated neurocalcins. Biochemistry (2001) 0.78
Affinity-based chromatography utilizing genetically engineered proteins. Interaction of Bordetella pertussis adenylate cyclase with calmodulin. J Biol Chem (1988) 0.77
Characterization of a beta-galactosidase hybrid protein carrying the catalytic domain of Escherichia coli adenylate cyclase. Eur J Biochem (1986) 0.77
The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells. Toxicon (2002) 0.76
Bordetella pertussis adenylate cyclase: a toxin with multiple talents. Zentralbl Bakteriol (1993) 0.76
Purification and immunological characterization of bacterial and secreted adenylate cyclase of "Bordetella pertussis". Ann Sclavo Collana Monogr (1986) 0.75
Gene isolation by direct in situ cAMP binding. Gene (1987) 0.75