Autocrine stimulation of a human lung mesothelioma cell line is mediated through the transforming growth factor alpha/epidermal growth factor receptor mitogenic pathway.

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Published in Br J Cancer on November 01, 1994

Authors

I A Mórocz1, D Schmitter, B Lauber, R A Stahel

Author Affiliations

1: Department of Medicine, University Hospital, Zurich, Switzerland.

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Multiple mechanisms for the carcinogenic effects of asbestos and other mineral fibers. Environ Health Perspect (1989) 1.02

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Loss of growth responsiveness to epidermal growth factor and enhanced production of alpha-transforming growth factors in ras-transformed mouse mammary epithelial cells. J Cell Physiol (1987) 0.93

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Growth factors: regulation of normal and neoplastic growth. J Pathol (1993) 0.90

Tumorigenicity of human mesothelial cell line transfected with EJ-ras oncogene. J Natl Cancer Inst (1989) 0.89

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Anchorage-independent growth of normal human mesothelial cells: a sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum. In Vitro Cell Dev Biol (1985) 0.87

Human epidemiology: a review of fiber type and characteristics in the development of malignant and nonmalignant disease. Environ Health Perspect (1990) 0.87

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Differential responses to growth factors by normal human mesothelial cultures from individual donors. J Cell Physiol (1989) 0.84

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Biotinylated epidermal growth factor: a useful tool for the histochemical analysis of specific binding sites. Histochem J (1990) 0.81

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