J K Belknap

Author PubWeight™ 115.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology (Berl) 1997 5.03
2 In silico mapping of complex disease-related traits in mice. Science 2001 4.67
3 Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception. Pain 1999 2.87
4 Localization of genes affecting alcohol drinking in mice. Alcohol Clin Exp Res 1994 2.14
5 Quantitative trait loci affecting peak bone mineral density in mice. J Bone Miner Res 1998 2.08
6 Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals. Alcohol Clin Exp Res 1990 2.03
7 Gender specificity in the genetic determinants of peak bone mass. J Bone Miner Res 2001 1.80
8 High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption. Mamm Genome 1998 1.75
9 Intracerebroventricular injections in mice. Some methodological refinements. J Pharmacol Methods 1986 1.74
10 Genetic animal models of alcohol and drug abuse. Science 1994 1.61
11 Heritability of nociception II. 'Types' of nociception revealed by genetic correlation analysis. Pain 1999 1.53
12 Orphanin FQ is a functional anti-opioid peptide. Neuroscience 1996 1.48
13 Novel embryonic genes are preferentially expressed by autonomously replicating rat embryonic and neointimal smooth muscle cells. Circ Res 2000 1.45
14 Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice. J Neurosci 1997 1.41
15 Identifying genes for alcohol and drug sensitivity: recent progress and future directions. Trends Neurosci 1999 1.37
16 Acute dependence on depressant drugs is determined by common genes in mice. J Pharmacol Exp Ther 1991 1.26
17 Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ. Neurosci Lett 1996 1.25
18 Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media. J Clin Invest 1995 1.23
19 Genetic determinants of sensitivity to ethanol in inbred mice. Behav Neurosci 1994 1.12
20 Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. Psychopharmacology (Berl) 1991 1.11
21 Confirmation and fine mapping of chromosomal regions influencing peak bone mass in mice. J Bone Miner Res 2001 1.07
22 Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred mice. J Pharmacol Exp Ther 1996 1.06
23 Identification of a sex-specific quantitative trait locus mediating nonopioid stress-induced analgesia in female mice. J Neurosci 1997 1.05
24 Quantitative trait loci influencing morphine antinociception in four mapping populations. Mamm Genome 2001 1.04
25 Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains. J Neurosci 1997 1.03
26 Hybrid mice as genetic models of high alcohol consumption. Behav Genet 2009 1.02
27 Harnessing the mouse to unravel the genetics of human disease. Genes Brain Behav 2002 1.01
28 Preabsorptive vs. postabsorptive control of ethanol intake in C57BL/6J and DBA/2J mice. Behav Genet 1977 1.00
29 Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay. J Pharmacol Exp Ther 1996 0.99
30 Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice. Genes Brain Behav 2013 0.99
31 Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide. Neuroreport 1996 0.99
32 Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption. Mamm Genome 1998 0.99
33 Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by delta2-opioid receptors. Pain 1997 0.97
34 The genetics of pain and pain inhibition. Proc Natl Acad Sci U S A 1996 0.96
35 The alpha 3 subunit gene of the nicotinic acetylcholine receptor is a candidate gene for ethanol stimulation. Genes Brain Behav 2008 0.96
36 Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression. Brain Res 1999 0.94
37 Mapping genes that regulate density of dopamine transporters and correlated behaviors in recombinant inbred mice. J Pharmacol Exp Ther 2001 0.94
38 Effects of convulsants on handling-induced convulsions in mice selected for ethanol withdrawal severity. Brain Res 1991 0.94
39 Phenotypic characterization of mice bred for high and low peak bone mass. J Bone Miner Res 2001 0.92
40 Cocaine-induced seizure thresholds: quantitative trait loci detection and mapping in two populations derived from the C57BL/6 and DBA/2 mouse strains. J Pharmacol Exp Ther 2000 0.92
41 Drug withdrawal convulsions and susceptibility to convulsants after short-term selective breeding for acute ethanol withdrawal. Behav Brain Res 1998 0.92
42 Use of recombinant inbred strains for studying genetic determinants of responses to alcohol. Alcohol Alcohol Suppl 1994 0.90
43 Characterization of the quantitative trait locus for haloperidol-induced catalepsy on distal mouse chromosome 1. Genes Brain Behav 2007 0.90
44 Proinflammatory cytokine and chemokine gene expression profiles in subcutaneous and visceral adipose tissue depots of insulin-resistant and insulin-sensitive light breed horses. J Vet Intern Med 2010 0.90
45 Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice. J Pharmacol Exp Ther 1994 0.89
46 Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia. Pharmacol Biochem Behav 1997 0.89
47 Genetic analysis of sensitization and tolerance to cocaine. J Pharmacol Exp Ther 1994 0.89
48 Laminar inflammatory gene expression in the carbohydrate overload model of equine laminitis. Equine Vet J 2011 0.89
49 Genetic determinants of sensitivity to diazepam in inbred mice. Behav Neurosci 1998 0.89
50 Behavior genetic analyses of drug withdrawal. Alcohol Alcohol Suppl 1993 0.87
51 Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice. Behav Neurosci 1995 0.86
52 Disparate spinal and supraspinal opioid antinociceptive responses in beta-endorphin-deficient mutant mice. Neuroscience 2000 0.85
53 Genetic determinants of ethanol reinforcement. Ann N Y Acad Sci 1992 0.85
54 Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3. Genes Brain Behav 2008 0.85
55 Insulin resistance selectively alters cell-surface glucose transporters but not their total protein expression in equine skeletal muscle. J Vet Intern Med 2011 0.84
56 Hypothetical quantitative trait loci (QTL) for circadian period of locomotor activity in CXB recombinant inbred strains of mice. Behav Genet 1996 0.84
57 Laparoscopic ovariectomy using sequential electrocoagulation and sharp transection of the equine mesovarium. Vet Surg 2001 0.84
58 Increased expression of MAIL, a cytokine-associated nuclear protein, in the prodromal stage of black walnut-induced laminitis. Equine Vet J 2004 0.83
59 Heritability of the blood pressure response to acute ethanol exposure in five inbred strains of mice. Alcohol Clin Exp Res 2000 0.83
60 Laminar leukocyte accumulation in horses with carbohydrate overload-induced laminitis. J Vet Intern Med 2010 0.83
61 Alcohol withdrawal and magnesium deficiency in mice. Pharmacol Biochem Behav 1978 0.83
62 Use of recombinant inbred strains to assess vulnerability to drug abuse at the genetic level. J Addict Dis 1991 0.83
63 Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (Serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity. J Pharmacol Exp Ther 1999 0.82
64 Developmental regulation of perlecan gene expression in aortic smooth muscle cells. Matrix Biol 1996 0.81
65 Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia. Brain Res 1994 0.81
66 Genomewide search for epistasis in a complex trait: pentobarbital withdrawal convulsions in mice. Behav Genet 2001 0.81
67 Extrastriatal dopamine D2 receptors: distribution, pharmacological characterization and region-specific regulation by clozapine. J Pharmacol Exp Ther 1992 0.81
68 Proinflammatory cytokine responses of cultured equine keratinocytes to bacterial pathogen-associated molecular pattern motifs. Equine Vet J 2010 0.81
69 Naturally occurring compensated insulin resistance selectively alters glucose transporters in visceral and subcutaneous adipose tissues without change in AS160 activation. Biochim Biophys Acta 2011 0.81
70 Potential pleiotropic effects of Mpdz on vulnerability to seizures. Genes Brain Behav 2004 0.81
71 Stereotypic behaviors in mice selectively bred for high and low methamphetamine-induced stereotypic chewing. Psychopharmacology (Berl) 2001 0.81
72 Hexokinase redistribution in vivo. Biochim Biophys Acta 1990 0.80
73 Continuous digital hypothermia initiated after the onset of lameness prevents lamellar failure in the oligofructose laminitis model. Equine Vet J 2013 0.80
74 Expression and activity of collagenases in the digital laminae of horses with carbohydrate overload-induced acute laminitis. J Vet Intern Med 2013 0.79
75 Effect of acute alcohol withdrawal on sensitivity to pro- and anticonvulsant treatments in WSP mice. Alcohol Clin Exp Res 1993 0.79
76 Selective breeding for high and low levels of opiate-induced analgesia in mice. Behav Genet 1983 0.79
77 Distribution of insulin receptor and insulin-like growth factor-1 receptor in the digital laminae of mixed-breed ponies: an immunohistochemical study. Equine Vet J 2012 0.78
78 Expression of interleukin-1beta in the digital laminae of horses in the prodromal stage of experimentally induced laminitis. Am J Vet Res 2001 0.78
79 Identification of a locus on mouse chromosome 17 associated with high-affinity choline uptake using BXD recombinant inbred mice and quantitative trait loci analysis. Genomics 1995 0.78
80 Digital hypothermia inhibits early lamellar inflammatory signalling in the oligofructose laminitis model. Equine Vet J 2011 0.78
81 Lung endothelial cell proliferation in normal and pulmonary hypertensive neonatal calves. Am J Physiol 1998 0.78
82 Ganglioneuroma as a cause of small intestinal obstruction in the horse: a case report. Cornell Vet 1989 0.78
83 Alcohol dependence and withdrawal: a genetic animal model. Ann Med 1990 0.78
84 Laminar xanthine oxidase, superoxide dismutase and catalase activities in the prodromal stage of black-walnut induced equine laminitis. Equine Vet J 2007 0.77
85 Differential neurosensitivity to three alcohols and phenobarbital in C57BL/6J and DBA/2J mice. Behav Genet 1982 0.77
86 Genetic approaches to drug dependence. Trends Pharmacol Sci 1992 0.77
87 Acute morphine dependence in mice selectively-bred for high and low analgesia. Neurosci Lett 1998 0.77
88 Calprotectin in myeloid and epithelial cells of laminae from horses with black walnut extract-induced laminitis. J Vet Intern Med 2009 0.77
89 Effects of acute and chronic barbiturate administration on synaptosomal calcium accumulation. Mol Pharmacol 1979 0.77
90 Barbiturate physical dependence in mice: effects of neuroleptics and diazepam on the withdrawal syndrome. Clin Toxicol 1978 0.77
91 Nitrous oxide antinociception in BXD recombinant inbred mouse strains and identification of quantitative trait loci. Brain Res 1996 0.77
92 Tissue concentrations of 4-HNE in the black walnut extract model of laminitis: indication of oxidant stress in affected laminae. Vet Immunol Immunopathol 2008 0.77
93 NMDA receptor subunit mRNA and protein expression in ethanol-withdrawal seizure-prone and -resistant mice. Alcohol Clin Exp Res 2001 0.77
94 Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalities. Brain Res 1993 0.77
95 Sepsis-related laminitis. Equine Vet J 2012 0.77
96 Sensitivity to the anticonvulsant effects of ethanol and pentobarbital in mouse lines genetically selected for ethanol sensitivity. Alcohol Clin Exp Res 1989 0.76
97 Role of oxidative tissue injury in the pathophysiology of experimentally induced equine laminitis: a comparison of 2 models. J Vet Intern Med 2011 0.76
98 Sample preparation for inositol measurement: Sep-Pak C18 use in detergent removal. Anal Biochem 1986 0.76
99 Quantitative trait loci associated with the behavioral response of B x D recombinant inbred mice to restraint stress: a preliminary communication. Behav Genet 1995 0.76
100 Presence of mononuclear cells in normal and affected laminae from the black walnut extract model of laminitis. Equine Vet J 2011 0.76
101 Laminar regulation of STAT1 and STAT3 in black walnut extract and carbohydrate overload induced models of laminitis. J Vet Intern Med 2012 0.76
102 Strategies for identifying genes underlying drug abuse susceptibility. NIDA Res Monogr 1996 0.76
103 Quantitative trait loci for acute behavioral sensitivity to paraoxon. Neurotoxicol Teratol 2000 0.76
104 Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines. Behav Genet 1995 0.76
105 DSLET (D-ser2-leu5-enkephalin-Thr6) produces analgesia on the hot plate by mechanisms largely different from DAGO and morphine-like opioids. Life Sci 1987 0.76
106 Characterization of cultured smooth muscle cells obtained from the palmar digital arteries of horses. Am J Vet Res 2000 0.76
107 In vivo and in vitro evidence of the involvement of CXCL1, a keratinocyte-derived chemokine, in equine laminitis. J Vet Intern Med 2009 0.76
108 Quantitative trait loci: mapping drug and alcohol-related genes. Adv Pharmacol 1998 0.75
109 Effect of dietary nonstructural carbohydrate content on activation of 5'-adenosine monophosphate-activated protein kinase in liver, skeletal muscle, and digital laminae of lean and obese ponies. J Vet Intern Med 2014 0.75
110 Selective breeding for levorphanol-induced antinociception on the hot-plate assay: commonalities in mechanism of action with morphine, pentazocine, ethylketocyclazocine, U-50488H and clonidine in mice. J Pharmacol Exp Ther 1987 0.75
111 Detection and mapping of quantitative trait loci that determine responsiveness of mice to nitrous oxide antinociception. Neuroscience 2004 0.75
112 The D2 receptor gene. Science 1994 0.75
113 Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity. J Pharmacol Exp Ther 1986 0.75
114 Regulation of hypoxia-inducible factor-1α and related genes in equine digital lamellae and in cultured keratinocytes. Equine Vet J 2013 0.75
115 Investigation of mRNA expression of tumor necrosis factor-alpha, interleukin-1beta, and cyclooxygenase-2 in cultured equine digital artery smooth muscle cells after exposure to endotoxin. Am J Vet Res 2001 0.75
116 Barbiturate physical dependence in mice: effects on body temperature regulation. J Pharmacol Exp Ther 1981 0.75
117 Tolerance to barbiturate and chlorpromazine-induced central nervous system sedation -- involvement of calcium-mediated stimulus-secretion coupling. Biochem Pharmacol 1979 0.75
118 The effects of alcohol withdrawal and acute doses of alcohol on the acid-base balance in mice and rats. Drug Alcohol Depend 1982 0.75
119 Internet resources for genomic, bioinformatics, and medical genetics information. Curr Protoc Neurosci 2003 0.75
120 Barbiturate dependence in mice: effects of continuous vs. discontinuous drug administration. Psychopharmacology (Berl) 1977 0.75
121 Allosteric regulation of the N-methyl-D-aspartate receptor-linked ion channel complex and effects of ethanol in ethanol-withdrawal seizure-prone and -resistant mice. J Neurochem 1995 0.75
122 Barbiturate dependence in mice: effects of propranolol on the withdrawal syndrome. Proc Soc Exp Biol Med 1980 0.75
123 Barbiturate dependence in mice: evidence for beta-adrenergic receptor proliferation in brain. Res Commun Chem Pathol Pharmacol 1978 0.75
124 Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia. Brain Res 1999 0.75
125 Intercorrelations between levorphanol induced antinociception, hypothermia, activity and constipation in a genetically heterogeneous mouse population, and the results of selective breeding for antinociception. Proc West Pharmacol Soc 1982 0.75
126 Commonalities between gas anesthetics (nitrous oxide, nitrogen and/or argon) and ethanol intoxication in hot and cold selection line mice. Biomed Sci Instrum 1991 0.75
127 Handling-induced convulsions (HIC) as a sensitive index of hyperexcitability associated with the high pressure nervous syndrome (HPNS). Biomed Sci Instrum 1988 0.75
128 Induction and reversal of the magnesium deficiency syndrome in inbred mice. Exp Neurol 1977 0.75
129 Barbiturate withdrawal and magnesium deficiency in mice. Psychopharmacology (Berl) 1978 0.75
130 Ethanol sleep times and hepatic alcohol and aldehyde dehydrogenase activities in mice. Physiol Behav 1972 0.75
131 Hindlimb laminar inflammatory response is similar to that present in forelimbs after carbohydrate overload in horses. Equine Vet J 2011 0.75
132 Effect of intravenous lidocaine administration on laminar inflammation in the black walnut extract model of laminitis. Equine Vet J 2010 0.75
133 Pharmacogenetic tools in the study of drug tolerance and dependence. Subst Alcohol Actions Misuse 1980 0.75